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GPCR/Proteína-G

GPCR/Proteína-G

Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.

Subcategorias de "GPCR/Proteína-G"

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Foram encontrados 5352 produtos de "GPCR/Proteína-G"

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  • RWJ 676070
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    RWJ 676070

    CAS:
    <p>RWJ 676070 is an antagonist of vasopressin V1A/V2 receptor.</p>
    Fórmula:C30H26ClFN2O5
    Cor e Forma:Solid
    Peso molecular:548.99

    Ref: TM-T28629

  • Benzoquinamide hydrochloride
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    Benzoquinamide hydrochloride

    CAS:
    <p>Benzoquinamide hydrochloride (3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride) is an antiemetic</p>
    Fórmula:C22H33ClN2O5
    Pureza:97.13% - 99.56%
    Cor e Forma:Solid
    Peso molecular:440.96

    Ref: TM-T9881

  • P2Y14 antagonist 1
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    P2Y14 antagonist 1

    <p>P2Y14 antagonist 1 (compound 45) is a highly selective and orally active P2Y14 receptor antagonist with an IC50 value of 0.70 nM. It demonstrates significant anti-inflammatory effects by effectively reducing pulmonary infiltration of immune cells and inflammatory responses through the inhibition of the NLRP3 signaling pathway. P2Y14 antagonist 1 is suitable for studying acute lung injury.</p>
    Fórmula:C24H21N3O3
    Cor e Forma:Solid
    Peso molecular:399.442

    Ref: TM-T205734

  • M617
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    M617

    CAS:
    <p>Galanin GAL1 agonist, Ki: GAL1 0.23 nM, GAL2 5.71 nM; boosts rat appetite, lessens inflammation pain.</p>
    Fórmula:C112H161N29O28
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2361.68

    Ref: TM-TP1993

  • 15(S)-15-methyl Prostaglandin E2
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    15(S)-15-methyl Prostaglandin E2

    CAS:
    <p>15(S)-15-methyl PGE2: A stable PGE2 analog; strong antiulcer with double PGE2 affinity; excels PGE1 in uterine contraction.</p>
    Fórmula:C21H34O5
    Cor e Forma:Solid
    Peso molecular:366.49

    Ref: TM-T36154

  • Logotipo do CymitQuimica
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    GLI1-IN-3

    <p>GLI1-IN-3 (Compound 11a) is a triterpenoid-like compound that inhibits Hedgehog signaling in cancer cells with GLI1 overexpression. It suppresses the proliferation of non-small cell lung cancer and prostate cancer cell lines with excessive Hh signaling activation. Additionally, GLI1-IN-3 reduces the expression of GLI1 protein and its target genes associated with tumor progression and proliferation in A549 and DU-145 cancer cells.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T206757

  • GLP-1 receptor agonist 4
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    GLP-1 receptor agonist 4

    CAS:
    <p>GLP-1 receptor agonist 4 targets GLP-1R, EC50 64.5 nM, potential diabetes treatment research.</p>
    Fórmula:C51H44Cl2N4O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:879.82

    Ref: TM-T11405

  • PZ-128
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    PZ-128

    CAS:
    <p>PZ-128, a PAR1 antagonist, is used potentially for the treatment of thrombosis.</p>
    Fórmula:C55H99N13O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1086.46

    Ref: TM-T28477

  • Cetirizine methyl ester
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    Cetirizine methyl ester

    CAS:
    <p>Cetirizine methyl ester is a Cetirizine impurity, a long-acting, oral H1-antihistamine and hydroxyzine metabolite.</p>
    Fórmula:C22H27ClN2O3
    Cor e Forma:Solid
    Peso molecular:402.91

    Ref: TM-T73933

  • Fasitibant chloride hydrochloride
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    Fasitibant chloride hydrochloride

    CAS:
    <p>Fasitibant chloride( MEN16132) is an effective and selective non-peptide antagonist of kinin B2 receptor.</p>
    Fórmula:C36H50Cl4N6O6S
    Cor e Forma:Solid
    Peso molecular:836.7

    Ref: TM-T31747

  • SR-31747 free base
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    SR-31747 free base

    CAS:
    <p>SR-31747: immunosuppressive anti-inflammatory agent, inhibits cell growth by blocking sterol isomerase.</p>
    Fórmula:C23H34ClN
    Cor e Forma:Solid
    Peso molecular:359.98

    Ref: TM-T38720

  • Adrenomedullin (16-31), human
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    Adrenomedullin (16-31), human

    CAS:
    <p>Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM).</p>
    Fórmula:C82H129N25O21S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1865.19

    Ref: TM-TP1486

  • ACTH (11-24)
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    ACTH (11-24)

    CAS:
    <p>ACTH (11-24) is an adrenocorticotrophin fragment, stimulates cortisol, and antagonizes ACTH (1-39)/(1-10) in adrenal cells.</p>
    Fórmula:C77H134N24O16
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1652.04

    Ref: TM-TP1248

  • 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide
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    17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide

    CAS:
    <p>Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis.</p>
    Fórmula:C27H39NO4
    Cor e Forma:Solid
    Peso molecular:441.612

    Ref: TM-T37941

  • Plecanatide acetate
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    Plecanatide acetate

    CAS:
    <p>Plecanatide acetate: GC-C receptor agonist, EC50=190 nM (T84 cells), anti-inflammatory in murine colitis.</p>
    Fórmula:C67H108N18O28S4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1741.94

    Ref: TM-T12501

  • Besipirdine hydrochloride
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    Besipirdine hydrochloride

    CAS:
    <p>Besipirdine hydrochloride is a non-receptor-dependent cholinomimetic compound with cardiovascular activity that inhibits the uptake of biogenic amines.</p>
    Fórmula:C16H18ClN3
    Pureza:98.45%
    Cor e Forma:Soild
    Peso molecular:287.79

    Ref: TM-T26778L

  • Hemokinin 1 (mouse)
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    Hemokinin 1 (mouse)

    CAS:
    <p>Hemokinin 1 (mouse) is a selective excitogen 1 receptor agonist with a Ki value of 0.175 nM for the human NK1 receptor and 560 nM for the human NK2 receptor.</p>
    Fórmula:C61H100N22O15S
    Pureza:98%
    Cor e Forma:White Powder
    Peso molecular:1413.65

    Ref: TM-TP1772

  • 16-phenoxy tetranor Prostaglandin F2α methyl ester
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    16-phenoxy tetranor Prostaglandin F2α methyl ester

    CAS:
    <p>Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.</p>
    Fórmula:C23H32O6
    Cor e Forma:Solid
    Peso molecular:404.503

    Ref: TM-T37937

  • allo-Yohimbine
    Targetmol
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    allo-Yohimbine

    CAS:
    <p>allo-Yohimbine is a biochemical.</p>
    Fórmula:C21H26N2O3
    Cor e Forma:Solid
    Peso molecular:354.44

    Ref: TM-T29884

  • RC-3095
    Targetmol
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    RC-3095

    CAS:
    <p>RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.</p>
    Fórmula:C56H79N15O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1106.32

    Ref: TM-TP1470