GPCR/Proteína-G

Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.

Subcategorias de "GPCR/Proteína-G"

Exibir 18 mais subcategorias

Foram encontrados 5378 produtos de "GPCR/Proteína-G"

Pureza (%)

100

produtos por página.

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[Gln8]-C517 (LH-RH), chicken
CAS:
- 47922-48-5
[Gln8] LH-RH: Avian hypothalamic peptide; prompts anterior pituitary to release gonadotropins, controlling reproduction.
Fórmula:C₅₄H₇₁N₁₅O₁₄
Pureza:98%
Cor e Forma:Solid
Peso molecular:1154.23
Ref: TM-TP1648
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Bim 21009
CAS:
- 106881-54-3
Bim 21009 is an inhibitor of gonadorelin.
Fórmula:C₇₄H₉₂ClN₁₇O₁₃
Pureza:98%
Cor e Forma:Solid
Peso molecular:1463.08
Ref: TM-T25154
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α-Helical CRF(9-41)
CAS:
- 90880-23-2
Corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).
Fórmula:C₁₆₆H₂₇₄N₄₆O₅₃S₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:3827
Ref: TM-TP2048
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Adenosine receptor antagonist 1
CAS:
- 2682930-40-9
A2aR-selective antagonist with IC50 of 0.29 nM; 14x more selective over A2bR.
Fórmula:C₂₂H₁₅ClFN₇O
Cor e Forma:Solid
Peso molecular:447.86
Ref: TM-T40307
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Vapiprost hydrochloride
CAS:
- 87248-13-3
Vapiprost hydrochloride is a biochemicla.
Fórmula:C₃₀H₄₀ClNO₄
Cor e Forma:Solid
Peso molecular:514.1
Ref: TM-T35038
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TRV045
CAS:
- 2256030-24-5
TRV045 is a selective agonist of the sphingosine-1-phosphate (S1P) subtype 1 receptor and does not impact lymphocyte trafficking. It possesses antiepileptic properties.
Fórmula:C₁₈H₁₈N₄O₃
Cor e Forma:Solid
Peso molecular:338.36
Ref: TM-T203071
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SGLT1/2-IN-2
CAS:
- 2387812-73-7
SGLT1/2-IN-2 is a chemical compound with robust dual inhibitory properties, exhibiting potent activities against SGLT1 (IC50 = 96 nM) and SGLT2 (IC50 = 1.3 nM).
Fórmula:C₂₃H₂₆F₂O₇
Cor e Forma:Solid
Peso molecular:452.451
Ref: TM-T39966
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Gulgafafusp alfa
CAS:
- 2642374-02-3
Gulgafafusp alfa is a human IgG2κ monoclonal antibody that selectively binds to the glucagon-like peptide 1 receptor (GLP1R) [1].
Cor e Forma:Liquid
Ref: TM-T80565
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Mapenterol hydrochloride
CAS:
- 54238-51-6
Mapenterol hydrochloride is an agonist of β2-adrenergic receptor.
Fórmula:C₁₄H₂₁Cl₂F₃N₂O
Pureza:98.11% - 99.98%
Cor e Forma:Solid
Peso molecular:361.23
Ref: TM-T40622
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BMS-604992 free base
CAS:
- 760944-56-7
BMS-604992 (EX-1314), a selective GHSR agonist, binds strongly (ki=2.3 nM), is orally active, and increases rodent food intake.
Fórmula:C₂₄H₃₁N₇O₅
Cor e Forma:Solid
Peso molecular:497.556
Ref: TM-T40876
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Bradykinin (1-7)
CAS:
- 23815-87-4
Bradykinin (1-7), an amino-truncated peptide derived from Bradykinin, is a metabolite formed through enzymatic cleavage by endopeptidase.
Fórmula:C₃₅H₅₂N₁₀O₉
Pureza:98%
Cor e Forma:White Lyophilized Powder
Peso molecular:756.85
Ref: TM-TP1210
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GLP-1R agonist 27
GLP-1R agonist 27 (compound 21) is a potent and orally active GLP-1R agonist. It enhances the accumulation of cyclic adenosine monophosphate (cAMP), reduces blood glucose levels, and decreases food intake. GLP-1R agonist 27 shows potential for research in obesity and type 2 diabetes mellitus (T2DM).
Fórmula:C₃₂H₃₃N₅O₄Se
Cor e Forma:Solid
Peso molecular:630.6
Ref: TM-T204289
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(S)-Osanetant
CAS:
- 182621-58-5
(S)-Osanetant, an S-enantiomer, is a selective NK3 antagonist with potential for treating schizophrenia and has anxiolytic and antidepressant effects.
Fórmula:C₃₅H₄₁Cl₂N₃O₂
Cor e Forma:Solid
Peso molecular:606.62
Ref: TM-T74413
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NI-203
NI-203 is a monoclonal antibody inhibitor that targets amylin and shows potential for research in type 2 diabetes.
Cor e Forma:Odour Liquid
Ref: TM-T9901A-993
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Mosliciguat
CAS:
- 2231749-54-3
Mosliciguat is a guanylate cyclase activator.
Fórmula:C₄₁H₃₆ClF₃N₂O₅
Cor e Forma:Solid
Peso molecular:729.19
Ref: TM-T39723
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Sufotidine
CAS:
- 80343-63-1
Sufotidine (AH 25352X) is a highly selective competitive H2 receptor antagonist.
Fórmula:C₂₀H₃₁N₅O₃S
Pureza:99.03% - 99.92%
Cor e Forma:Solid
Peso molecular:421.56
Ref: TM-T68146
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SC 31391
CAS:
- 144730-93-8
SC 31391 is a PGE1 analog.
Fórmula:C₂₄H₃₂O₆
Cor e Forma:Solid
Peso molecular:416.51
Ref: TM-T34550
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Paynantheine
CAS:
- 4697-66-9
Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.
Fórmula:C₂₃H₂₈N₂O₄
Cor e Forma:Solid
Peso molecular:396.48
Ref: TM-T203202
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γ1-MSH
CAS:
- 72629-65-3
Endogenous melanocortin MC3 receptor agonist (pKi = 7.46) that displays ~ 40-fold selectivity over MC4.
Fórmula:C₇₂H₉₇N₂₁O₁₄S
Pureza:98%
Cor e Forma:Solid
Peso molecular:1512.76
Ref: TM-TP1892
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L-803087 TFA
CAS:
- 1786412-46-1
L-803087 TFA: potent sst4 agonist, Ki=0.7 nM, >280x selective vs other somatostatin receptors; boosts AMPA, heightens seizures.
Fórmula:C₂₇H₃₀F₅N₅O₅
Cor e Forma:Solid
Peso molecular:599.55
Ref: TM-T39207