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GPCR/Proteína-G

GPCR/Proteína-G

Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.

Subcategorias de "GPCR/Proteína-G"

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Foram encontrados 5352 produtos de "GPCR/Proteína-G"

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  • UMB24

    CAS:
    <p>UMB24 is an effective antagonist of the σ2 receptor, exhibiting dissociation constants (Ki values) of 170 nM for the σ2 receptor and 322 nM for the σ1 receptor. This compound mitigates cocaine-induced convulsions and hyperactivity without causing mortality.</p>
    Fórmula:C17H21N3
    Cor e Forma:Solid
    Peso molecular:267.37
  • hA3AR agonist 1


    <p>hA3AR agonist 1 is a potent human A 3 adenosine receptor (hA 3 AR) agonist (Ki = 2.40 nM) .</p>
    Fórmula:C10H14N6OS
    Cor e Forma:Solid
    Peso molecular:266.32
  • S1PR1 agonist 1

    CAS:
    <p>S1PR1 agonist 1 is a potent agonist of S1PR1. S1PR1 agonist 1 has potential in autoimmune diseases.</p>
    Fórmula:C29H30N4O4
    Cor e Forma:Solid
    Peso molecular:498.57
  • MK-3207

    CAS:
    <p>MK-3207 is a potent, oral CGRP receptor antagonist with high selectivity for human and monkey receptors, inhibiting blood flow in vivo.</p>
    Fórmula:C31H29F2N5O3
    Cor e Forma:Solid
    Peso molecular:557.59
  • Leukotriene B4 dimethyl amide

    CAS:
    <p>LTB4 dimethyl amide: inhibits human neutrophil degranulation and rat lysozyme release; antagonizes LTB4 receptor on guinea pig lung membranes (Ki = 130 nM).</p>
    Fórmula:C22H37NO3
    Cor e Forma:Solid
    Peso molecular:363.53
  • Rodatristat

    CAS:
    <p>Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).</p>
    Fórmula:C27H27ClF3N5O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:561.98
  • MrgprX2 antagonist-7


    <p>MrgprX2 antagonist-7 is an anti-allergic agent with significant anti-allergic effects and inhibits mast cell degranulation.</p>
    Fórmula:C24H22ClF3N6O3
    Cor e Forma:Solid
    Peso molecular:534.92
  • 1'-Naphthoyl-2-methylindole

    CAS:
    <p>1'-Naphthoyl-2-methylindole (Compound 88) acts as a cannabinoid mimic and an inhibitor of Win 55212-2, displaying a 34% inhibition of [3H]Win 55212-2 binding to cannabinoid receptors at a concentration of 3 μM.</p>
    Fórmula:C20H15NO
    Cor e Forma:Solid
    Peso molecular:285.34
  • SAR-150640

    CAS:
    <p>SAR-150640, a selective β3-adrenergic receptor agonist, prevents an increase in MMP activity and production observed after LPS stimulation or in cases of chorioamnionitis.</p>
    Fórmula:C25H35ClN2O7S
    Cor e Forma:Solid
    Peso molecular:543.07
  • GAT564


    <p>GAT564, an allosteric CB1R modulator, shows EC50s of 87 nM (cAMP) &amp; 320 nM (β-arrestin2) and lowers IOP effectively in glaucoma mice.</p>
    Fórmula:C20H16N2O2S
    Cor e Forma:Solid
    Peso molecular:348.42
  • GPR27 agonist-1

    CAS:
    <p>GPR27 agonist-1 (compound I) is a selective agonist for GPR27 with a pEC50 value of 6.34.</p>
    Fórmula:C19H14Cl2N2O3S
    Cor e Forma:Solid
    Peso molecular:421.30
  • BAY 38-7271

    CAS:
    <p>BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) &amp; 5.96 nM (CB2).</p>
    Fórmula:C20H21F3O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:430.44
  • MDA77

    CAS:
    <p>MDA77 is a CB2 agonist with an EC50 value of 5.82 nM and exhibits no activity towards CB1.</p>
    Fórmula:C21H23N3O3
    Cor e Forma:Solid
    Peso molecular:365.43
  • A1/A3 AR antagonist 1


    <p>Compound 10 is a potent dual A1/A3 AR antagonist, with Ki values of 37.6 nM (hA1), 25.4 nM (hA3), and 1.47 nM (rA1), studied in renal, lung, and Alzheimer's.</p>
    Fórmula:C24H18N2O3S
    Cor e Forma:Solid
    Peso molecular:414.48
  • DM-4111

    CAS:
    <p>DM-4111, one of the primary monohydroxy metabolites of Tolvaptan, is an effective vasopressin V2 receptor (vasopressin V2 receptor) inhibitor. By inhibiting water reabsorption in renal tubules, it facilitates the excretion of electrolyte-free water. DM-4111 holds potential for research in cardiovascular diseases.</p>
    Fórmula:C26H25ClN2O4
    Cor e Forma:Solid
    Peso molecular:464.94
  • UR-AK49

    CAS:
    <p>UR-AK49 (compound 11) is an agonist for the human histamine H1 and H2 receptors. It exhibits an EC50 of 23 nM in the GTPase assay involving hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. UR-AK49 is applicable in neurologically related research.</p>
    Fórmula:C16H27N5O
    Cor e Forma:Solid
    Peso molecular:305.42
  • MRS2279 diammonium

    CAS:
    <p>MRS2279 diammonium, a P2Y1 antagonist with K i 2.5 nM, IC 50 51.6 nM, blocks ADP-induced platelet aggregation, pK b 8.05.</p>
    Fórmula:C13H24ClN7O8P2
    Cor e Forma:Solid
    Peso molecular:503.77
  • Neladenoson

    CAS:
    <p>Neladenoson is an effective and selective agonist of the Adenosine A1 Receptor (A1R). EGFR-IN-162 shows potential for research in heart failure.</p>
    Fórmula:C29H24ClN5O2S2
    Cor e Forma:Solid
    Peso molecular:574.12
  • H3R antagonist 1

    CAS:
    <p>H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).</p>
    Fórmula:C19H23N3O3
    Cor e Forma:Solid
    Peso molecular:341.4
  • APJ receptor agonist 3

    CAS:
    <p>APJ receptor agonist 3 is a highly effective and orally administerable agonist of the APJ receptor, demonstrating a potent EC50 value of 0.027 nM.</p>
    Fórmula:C26H29ClN4O5
    Cor e Forma:Solid
    Peso molecular:512.98
  • BMS-986120

    CAS:
    BMS-986120: Oral, reversible PAR4 antagonist. IC50: 9.5 nM (human), 2.1 nM (monkey). Potent, selective antiplatelet.
    Fórmula:C23H23N5O5S2
    Cor e Forma:Solid
    Peso molecular:513.59
  • CCR1 antagonist 13

    CAS:
    <p>CCR1 antagonist13 is a selective small molecule antagonist of CCR1.</p>
    Fórmula:C25H27ClFN3O4
    Cor e Forma:Solid
    Peso molecular:487.95
  • Histamine H3 antagonist-1

    CAS:
    <p>Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].</p>
    Fórmula:C24H28F3N3O2
    Cor e Forma:Solid
    Peso molecular:447.49
  • VGD071

    CAS:
    <p>VGD071, a compound that targets sortilin, presents a promising avenue for forthcoming research utilizing mouse models of breast cancer.</p>
    Fórmula:C32H41N3O4S2
    Cor e Forma:Solid
    Peso molecular:595.82
  • NK-1 Antagonist 1

    CAS:
    <p>NK-1 Antagonist 1 is a NK-1 receptor antagonist.</p>
    Fórmula:C25H23F6N5O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:539.47
  • Taprostene

    CAS:
    <p>Taprostene (CG-4203), a stable Prostacyclin analogue, protects endothelium and myocardium post-ischemia in cats, with minimal hemodynamic impact.</p>
    Fórmula:C24H30O5
    Cor e Forma:Solid
    Peso molecular:398.49
  • YGZ-331

    CAS:
    <p>YGZ-331, a sedative hypnotic, acts by elevating GABA levels as a derivative of the adenosine nucleoside NGBA. It functions through activating A1R and A2aR, and inhibiting the phosphorylation of CaMKII (pCaMKII), thereby exerting its calming effects. Additionally, YGZ-331 reduces spontaneous motor activity in mice.</p>
    Fórmula:C19H23N5O4
    Cor e Forma:Solid
    Peso molecular:385.42
  • Lisuride

    CAS:
    <p>Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.</p>
    Fórmula:C20H26N4O
    Cor e Forma:Solid
    Peso molecular:338.45
  • MK-3207 Hydrochloride

    CAS:
    <p>MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.</p>
    Fórmula:C31H30ClF2N5O3
    Pureza:98.19%
    Cor e Forma:Solid
    Peso molecular:594.05
  • PD 136450

    CAS:
    <p>PD-136,450: partial stomach secretory agonist, full pancreas agonist in rats; potential acid-reducing drug, adjuvant for gastrin-sensitive tumors.</p>
    Fórmula:C35H40N4O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:612.72
  • FR-145715

    CAS:
    <p>FR-145715 is a histamine H2 receptor antagonist characterized by its specific anti-Helicobacter pylori activity. This compound is utilized in the study of gastric lesions.</p>
    Fórmula:C16H21N5O2S
    Cor e Forma:Solid
    Peso molecular:347.44
  • ATL444

    CAS:
    <p>ATL444 is an adenosine receptor antagonist with affinity (Ki values) for rA1AR, rA2AAR, rA2BAR, and rA3AR of 7.0, 2.5, 61.8, and &gt;1000 nM, respectively.</p>
    Fórmula:C17H19N5O
    Cor e Forma:Solid
    Peso molecular:309.37
  • Nipradolol

    CAS:
    <p>Nipradolol blocks alpha-1-adrenergic receptors, lowers IOP in rabbits, and reduces NA-induced muscle contraction and dog artery vasodilation.</p>
    Fórmula:C15H22N2O6
    Cor e Forma:Solid
    Peso molecular:326.35
  • Iralukast (CGP 45715A)

    CAS:
    <p>Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.</p>
    Fórmula:C38H37F3O8S
    Cor e Forma:Solid
    Peso molecular:710.76
  • HU 433

    CAS:
    <p>HU 433, a synthetic cannabinoid, acts as a CB2 receptor agonist and is an enantiomer of HU 308. It provides anti-inflammatory and neuroprotective effects by binding to the CB2 receptor, primarily found on immune cells, thereby modulating immune responses and inflammation. Additionally, HU 433 influences microglial signaling pathways, particularly LPS and IFNγ-mediated routes, affecting the phosphorylation of MAPKs, including ERK1/2, JNK, p38, and Akt. This compound is valuable in researching neuroinflammation and retinal diseases.</p>
    Fórmula:C27H42O3
    Cor e Forma:Solid
    Peso molecular:414.62
  • (2R,3S)-Azelaprag

    CAS:
    <p>(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist</p>
    Fórmula:C25H29N7O4S
    Pureza:97.47% - >99.99%
    Cor e Forma:Soild
    Peso molecular:523.61
  • VA012

    CAS:
    <p>VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. It has been shown to reduce food intake and prevent weight gain during subchronic administration without causing central nervous system-related discomfort. VA012 is applicable in obesity research.</p>
    Fórmula:C21H19N3
    Cor e Forma:Solid
    Peso molecular:313.40
  • R-137696

    CAS:
    <p>R-137696 is an orally active 5-HT1A receptor agonist that facilitates the relaxation of the proximal stomach. It is utilized in research related to functional dyspepsia.</p>
    Fórmula:C17H23N3O2
    Cor e Forma:Solid
    Peso molecular:301.38
  • BAY-899

    CAS:
    <p>BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.</p>
    Fórmula:C25H19F2N5O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:459.45
  • Flucopride

    CAS:
    <p>Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.</p>
    Fórmula:C22H33FN2O2
    Cor e Forma:Solid
    Peso molecular:376.51
  • AL 6598

    CAS:
    <p>AL 6598, a prodrug of PGD2 agonist AL 6556, reduces IOP by 53% at 1μg twice daily in monkeys; binds DP receptors with Ki of 3.2μM.</p>
    Fórmula:C23H39ClO5
    Cor e Forma:Solid
    Peso molecular:431.01
  • ATX inhibitor 27

    CAS:
    <p>ATX inhibitor 27 (Compound 31) is an ATX inhibitor. It demonstrates IC50 values of 13 nM against human autotaxin (hATX) and 23 nM against lysophosphatidylcholine (LPC). By inhibiting the ATX enzyme, ATX inhibitor 27 reduces LPA levels in the body. This compound is applicable in research related to ATX-LPA-associated conditions such as inflammation, neurodegenerative disorders, and cancer.</p>
    Fórmula:C26H26ClN5O3
    Cor e Forma:Solid
    Peso molecular:491.97
  • (S)-Bucindolol

    CAS:
    (S)-Bucindolol is an enantiomer of bucindolol, specifically a β1-adrenergic receptor antagonist. It is primarily utilized in research related to heart failure.
    Fórmula:C22H25N3O2
    Cor e Forma:Solid
    Peso molecular:363.45
  • CVN766

    CAS:
    <p>CVN766 is an orally active orexin 1 receptor antagonist with blood-brain permeability, demonstrating IC50 values of 8 nM for OX1R and &gt;10 μM for OX2R. CVN766 can be used to study schizophrenia [1].</p>
    Fórmula:C20H21F3N8O
    Cor e Forma:Solid
    Peso molecular:446.43
  • AFP-07

    CAS:
    <p>AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor.</p>
    Fórmula:C22H29F2NaO5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:434.45
  • TAAR1 agonist 2

    CAS:
    <p>TAAR1 agonist 2 (compound 30), a full agonist at trace amine-associated receptor 1 (TAAR1) (pEC50=7.5), also displays agonistic properties at H1 receptors and activates various muscarinic acetylcholine receptors, including the M2 receptor (pEC50=5). This compound is utilized in researching neuropsychiatric diseases.</p>
    Fórmula:C9H11NO
    Cor e Forma:Solid
    Peso molecular:149.19
  • SEP-363856 mesylate

    CAS:
    <p>SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.</p>
    Fórmula:C10H17NO4S2
    Cor e Forma:Solid
    Peso molecular:279.38
  • Monlunabant

    CAS:
    <p>Monlunabant ((S)-MRI-1891), a solid dispersion compound, functions as an inhibitor of the cannabinoid CB1 receptor [1].</p>
    Fórmula:C26H22ClF3N6O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:591.00
  • NBI 35965 hydrochloride

    CAS:
    <p>NBI 35965 hydrochloride is a selective CRF1 (corticotropin-releasing factor receptor 1) antagonist that is both orally active and capable of penetrating the brain. It possesses a K i value of 4 nM and a pK i of 8.5, and does not affect CRF2. This compound effectively diminishes CRF or stress-triggered ACTH (adrenocorticotropic hormone) production in vivo, demonstrating pIC 50 values of 7.1 and 6.9. Additionally, NBI 35965 hydrochloride exhibits anxiolytic properties [1] [2].</p>
    Fórmula:C21H23Cl3N4
    Cor e Forma:Solid
    Peso molecular:437.79
  • L-365260 hemihydrate


    <p>L-365260 hemihydrate: selective oral CCK-B/gastrin blocker, Ki=1.9/2.0 nM, competes with guinea pig receptors.</p>
    Fórmula:C24H24N4O3
    Cor e Forma:Solid
    Peso molecular:407.47
  • SSTR5 antagonist 6

    CAS:
    <p>SSTR5 antagonist 6, an orally active antagonist specific to the somatostatin receptor subtype 5 (SSTR5), exhibits an IC50 value of 24 nM. This compound is utilized in researching type 2 diabetes [1].</p>
    Fórmula:C22H28ClN3O4
    Cor e Forma:Solid
    Peso molecular:433.93
  • AGH-107

    CAS:
    <p>AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.</p>
    Fórmula:C13H12IN3
    Cor e Forma:Solid
    Peso molecular:337.16
  • Sulamserod hydrochloride

    CAS:
    <p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>
    Fórmula:C19H29Cl2N3O5S
    Cor e Forma:Solid
    Peso molecular:482.42
  • AM8936


    <p>AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.</p>
    Fórmula:C25H33NO3
    Cor e Forma:Solid
    Peso molecular:395.53
  • DA-302168S

    CAS:
    <p>DA-302168S is an orally active, selective GLP-1R agonist with an EC50 value of 1.32 nM. It promotes insulin secretion and has a hypoglycemic effect. Additionally, DA-302168S reduces food intake. It primarily activates GLP-1R in humans and monkeys, with minimal effect on GLP-1R in rats, mice, and dogs. DA-302168S can be used for research in type 2 diabetes and obesity.</p>
    Fórmula:C33H24ClF2N3O5
    Cor e Forma:Solid
    Peso molecular:616.011
  • MRGPRX1 agonist 4


    <p>Potent, oral MRGPRX1 agonist 4 modulates receptor positively (EC50: 0.1 μM) and reduces mice's thermal allergy response.</p>
    Fórmula:C23H17Cl2F3N2O2S
    Cor e Forma:Solid
    Peso molecular:513.36
  • LP 12 hydrochloride hydrate


    <p>LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.</p>
    Fórmula:C32H39N3O·HCl·xH2O
    Cor e Forma:Solid
  • H3R antagonist 5

    CAS:
    <p>H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.</p>
    Fórmula:C23H32N2O4
    Cor e Forma:Solid
    Peso molecular:400.511
  • RTIOXA-43

    CAS:
    <p>RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.</p>
    Fórmula:C37H37N5O5S
    Pureza:99.17%
    Cor e Forma:Solid
    Peso molecular:663.79
  • 2,3-dinor-11β-Prostaglandin F2α

    CAS:
    <p>2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where</p>
    Fórmula:C18H30O5
    Cor e Forma:Solid
    Peso molecular:326.43
  • CCR1 antagonist 11 hydrochloride


    <p>Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.</p>
    Cor e Forma:Solid
  • Ro4368554

    CAS:
    <p>Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.</p>
    Fórmula:C19H21N3O2S
    Cor e Forma:Solid
    Peso molecular:355.454
  • Dopamine D3 receptor antagonist-2


    <p>Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.</p>
    Fórmula:C23H27Cl2N3O3
    Cor e Forma:Solid
    Peso molecular:464.38
  • H1R ligand-1

    CAS:
    <p>H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.</p>
    Fórmula:C19H23NO
    Cor e Forma:Solid
    Peso molecular:281.392
  • TAK-637

    CAS:
    <p>TAK-637 is a tachykinin 1 (NK1) receptor antagonist.</p>
    Fórmula:C30H25F6N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:573.53
  • SGL5213

    CAS:
    <p>SGL5213 is a potent oral SGLT1 inhibitor (IC50: 29 nM) with potential for treating type 2 diabetes.</p>
    Fórmula:C37H55N3O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:669.85
  • BRD50837

    CAS:
    <p>BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).</p>
    Fórmula:C26H32ClN3O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:550.07
  • Tipindole

    CAS:
    <p>Tipindole is a serotonin antagonist utilized in research related to depression.</p>
    Fórmula:C16H20N2O2S
    Cor e Forma:Solid
    Peso molecular:304.41
  • Sulfinalol hydrochloride

    CAS:
    <p>Sulfinalol hydrochloride is an orally active β-adrenoceptor (β-adrenoceptor) antagonist that exhibits direct vasodilatory activity. It is also classified as an antihypertensive agent.</p>
    Fórmula:C20H28ClNO4S
    Cor e Forma:Solid
    Peso molecular:413.96
  • NMDAR antagonist 5

    CAS:
    <p>NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET). It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 μM) and effective activity on monoamine transporters (SERT IC50= 1.1 μM, DAT IC50= 0.7 μM, NET IC50= 2.7 μM). NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50&gt; 100 μM; cardiac toxicity IC50= 24.5 μM). It has antidepressant properties and is useful for depression research.</p>
    Fórmula:C17H21N3
    Cor e Forma:Solid
    Peso molecular:267.369
  • Cloprostenol

    CAS:
    <p>Cloprostenol is a synthetic prostaglandin and PGF2α analogue used in animals to terminate pregnancy and induce corpus luteum dissolution.</p>
    Fórmula:C22H29ClO6
    Pureza:99.81%
    Cor e Forma:Clear Colorless To Light Yellowish Liquid
    Peso molecular:424.92
  • Serotonin maleate

    CAS:
    <p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>
    Fórmula:C14H16N2O5
    Cor e Forma:Solid
    Peso molecular:292.287
  • Alixorexton

    CAS:
    <p>Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.</p>
    Fórmula:C21H30N2O5S
    Cor e Forma:Solid
    Peso molecular:422.538
  • BNS808

    CAS:
    <p>BNS808 is an orally active, selective CB1R antagonist with an IC50 of 0.8 nM, demonstrating significant selectivity for CB2R and minimal brain penetration. It is being studied for the treatment of obesity and related metabolic complications, such as metabolic dysfunction-associated steatotic liver disease (MASLD). BNS808 reduces drug exposure to the central nervous system, enhancing safety, and minimizes drug interactions through high plasma protein binding.</p>
    Fórmula:C25H20Cl3N3O3S
    Cor e Forma:Solid
    Peso molecular:548.869
  • Becondogrel

    CAS:
    <p>Becondogrel (2-Oxoclopidogrel) is a metabolite of Clopidogrel. It irreversibly inhibits the P2Y12 receptor, thereby preventing platelet aggregation and thrombosis.</p>
    Fórmula:C16H16ClNO3S
    Cor e Forma:Solid
    Peso molecular:337.821
  • P2Y14R antagonist 4

    CAS:
    <p>Compound 25l, also known as P2Y14R antagonist 4, is an orally active antagonist of the P2Y14R receptor with an IC50 of 5.6 nM. It exhibits higher binding affinity for P2Y14R compared to other PPTN receptors. P2Y14R antagonist 4 also possesses anti-inflammatory properties, reducing the release of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α) induced by LPS.</p>
    Fórmula:C27H27F3N2O4S
    Cor e Forma:Solid
    Peso molecular:532.574
  • Gemilukast

    CAS:
    <p>Gemilukast (ONO-6950) is a cysteinyl leukotriene 1 and 2 receptor inhibitor that inhibits bronchoconstriction and is used in the treatment of asthma.</p>
    Fórmula:C36H37F2NO5
    Pureza:98.27% - 99.5%
    Cor e Forma:Solid
    Peso molecular:601.68
  • (R)-MrgprX2 antagonist-3

    CAS:
    <p>(R)-MrgprX2 antagonist-3 is an antagonist of MrgprX2. It is applicable in the study of inflammatory skin diseases. For more detailed information, please refer to compound E118 in patent document WO2021092240A1.</p>
    Fórmula:C16H20FN3O2S
    Peso molecular:337.41
  • Zaladenant

    CAS:
    <p>Zaladenant is an adenosine receptor antagonist with antitumor properties.</p>
    Fórmula:C19H15F3N6O
    Cor e Forma:Solid
    Peso molecular:400.357
  • BIIE-0246 HCl

    CAS:
    <p>BIIE-0246: A potent, non-peptide Y2 receptor antagonist; &gt;650-fold more selective than Y1, Y4, Y5.</p>
    Fórmula:C49H59Cl2N11O6
    Cor e Forma:Solid
    Peso molecular:968.97
  • D3/5-HT receptor modulator-1

    CAS:
    <p>D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.</p>
    Fórmula:C24H29N3O2
    Cor e Forma:Solid
    Peso molecular:391.506
  • 25B-NBOH hydrochloride

    CAS:
    <p>25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.</p>
    Fórmula:C17H21BrClNO3
    Cor e Forma:Solid
    Peso molecular:402.711
  • LY3154207

    CAS:
    <p>LY3154207: selective, potent oral human dopamine D1 receptor PAM, low agonist activity, EC50=3 nM.</p>
    Fórmula:C24H29Cl2NO3
    Cor e Forma:Solid
    Peso molecular:450.4
  • SJPYT-310

    CAS:
    <p>SJPYT-310 is a selective PXR antagonist, exhibiting no noticeable cytotoxicity.</p>
    Fórmula:C27H36N4O3
    Cor e Forma:Solid
    Peso molecular:464.6
  • Nifeviroc

    CAS:
    <p>Nifeviroc (TD-0232) is an orally active CCR5 antagonist, useful in HIV-1 infection research.</p>
    Fórmula:C33H42N4O6
    Pureza:98.14%
    Cor e Forma:Solid
    Peso molecular:590.71
  • GnRH-R antagonist 1

    CAS:
    <p>Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.</p>
    Fórmula:C31H28F5N7O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:721.65
  • RF9 hydrochloride


    <p>RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).</p>
    Fórmula:C26H39ClN6O3
    Cor e Forma:Solid
    Peso molecular:519.08
  • Dersimelagon

    CAS:
    <p>Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.</p>
    Fórmula:C36H45F4N3O5
    Pureza:97.35% - 98.23%
    Cor e Forma:Solid
    Peso molecular:675.75
  • Treprostinil diethanolamine

    CAS:
    <p>Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,</p>
    Fórmula:C27H45NO7
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:495.65
  • BQ-788

    CAS:
    <p>BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.</p>
    Fórmula:C34H51N5O7
    Pureza:98.81%
    Cor e Forma:Solid
    Peso molecular:641.8
  • AZD5462

    CAS:
    <p>AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.</p>
    Fórmula:C30H41FN2O6
    Pureza:98.32% - 99.63%
    Cor e Forma:Solid
    Peso molecular:544.65
  • PF-07258669

    CAS:
    <p>PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.</p>
    Fórmula:C25H27FN6O2
    Pureza:99.9%
    Cor e Forma:Solid
    Peso molecular:462.52
  • LSN3318839

    CAS:
    <p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>
    Fórmula:C26H23Cl2N3O2
    Pureza:99.21%
    Cor e Forma:Solid
    Peso molecular:480.39
  • SB-224289 hydrochloride

    CAS:
    <p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>
    Fórmula:C32H33ClN4O3
    Pureza:97.82% - 98.99%
    Cor e Forma:Solid
    Peso molecular:557.08
  • SB-423562

    CAS:
    <p>SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.</p>
    Fórmula:C26H32N2O4
    Pureza:99.22%
    Cor e Forma:Solid
    Peso molecular:436.54
  • AZD-5672

    CAS:
    <p>AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.</p>
    Fórmula:C32H38F2N2O5S2
    Pureza:98.1%
    Cor e Forma:Solid
    Peso molecular:632.78
  • BMS-986141

    CAS:
    <p>BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614</p>
    Fórmula:C27H23N5O5S2
    Pureza:98.43% - 99.26%
    Cor e Forma:Solid
    Peso molecular:561.63
  • Vofopitant dihydrochloride

    CAS:
    <p>Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.</p>
    Fórmula:C21H25Cl2F3N6O
    Pureza:98.99%
    Cor e Forma:Solid
    Peso molecular:505.36
  • Vofopitant

    CAS:
    <p>Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).</p>
    Fórmula:C21H23F3N6O
    Pureza:97.86%
    Cor e Forma:Solid
    Peso molecular:432.44
  • Rolapitant hydrochloride

    CAS:
    <p>Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki of 0.66 nM.</p>
    Fórmula:C25H27ClF6N2O2
    Pureza:98.35% - 99.79%
    Cor e Forma:Solid
    Peso molecular:536.94
  • Pumosetrag Hydrochloride

    CAS:
    <p>Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.</p>
    Fórmula:C15H18ClN3O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:339.84

    Ref: TM-T16683

    1mg
    Descontinuado
    Produto descontinuado
  • SR 146131

    CAS:
    <p>SR 146131 is a potent and selective agonist of the nonpeptide receptor.</p>
    Fórmula:C32H36ClN3O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:610.16

    Ref: TM-T16935

    1mg
    Descontinuado
    Produto descontinuado
  • Beraprost sodium

    CAS:
    <p>Beraprost sodium is a stable and orally active prodrug of PGI2.</p>
    Fórmula:C24H29NaO5
    Cor e Forma:Solid
    Peso molecular:420.481

    Ref: TM-T13859

    1mg
    Descontinuado
    Produto descontinuado
  • ML-00253764 hydrochloride

    CAS:
    <p>ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).</p>
    Fórmula:C18H19BrClFN2O
    Cor e Forma:Solid
    Peso molecular:413.71

    Ref: TM-T12072

    1mg
    Descontinuado
    Produto descontinuado
  • Arotinolol

    CAS:
    <p>Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.</p>
    Fórmula:C15H21N3O2S3
    Cor e Forma:White Solid
    Peso molecular:371.54

    Ref: TM-T10371

    1mg
    Descontinuado
    Produto descontinuado
  • (Rac)-Rotigotine hydrochloride

    CAS:
    <p>(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.</p>
    Fórmula:C19H26ClNOS
    Cor e Forma:Solid
    Peso molecular:351.93

    Ref: TM-T12676

    1ml*10 (DMSO)
    Descontinuado
    Produto descontinuado
  • SHA 68

    CAS:
    <p>SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR) with IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107.</p>
    Fórmula:C26H24FN3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:445.49

    Ref: TM-T12895

    1mg
    Descontinuado
    Produto descontinuado
  • 7-Desmethyl-agomelatine

    CAS:
    <p>7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.</p>
    Fórmula:C14H15NO2
    Cor e Forma:Solid
    Peso molecular:229.27

    Ref: TM-T10193

    1mg
    Descontinuado
    Produto descontinuado
  • Protease-Activated Receptor-4

    CAS:
    <p>Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.</p>
    Fórmula:C33H46N8O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:666.77

    Ref: TM-T7380

    1mg
    Descontinuado
    Produto descontinuado
  • HOKU-81

    CAS:
    <p>HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.</p>
    Fórmula:C12H18ClNO2
    Cor e Forma:Solid
    Peso molecular:243.73

    Ref: TM-T15498

    1mg
    Descontinuado
    Produto descontinuado
  • BIBP3226 TFA

    CAS:
    <p>BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).</p>
    Fórmula:C29H32F3N5O5
    Cor e Forma:Solid
    Peso molecular:587.59

    Ref: TM-T10540

    1mg
    Descontinuado
    Produto descontinuado
  • SB-399885 hydrochloride

    CAS:
    <p>SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.</p>
    Fórmula:C18H22Cl3N3O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:482.81

    Ref: TM-T12843

    1mg
    Descontinuado
    Produto descontinuado
  • ML-290

    CAS:
    <p>ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.</p>
    Fórmula:C24H21F3N2O5S
    Cor e Forma:Solid
    Peso molecular:506.49

    Ref: TM-T16101

    1mg
    Descontinuado
    Produto descontinuado
  • Metipranolol hydrochloride

    CAS:
    <p>Metipranolol hydrochloride is a non-selective β-adrenergic receptor blocking agent.</p>
    Fórmula:C17H28ClNO4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:345.86

    Ref: TM-T16066

    1mg
    Descontinuado
    2mg
    Descontinuado
    Produto descontinuado
  • CYM 9484

    CAS:
    <p>CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.</p>
    Fórmula:C27H31N3O3S2
    Cor e Forma:Solid
    Peso molecular:509.68

    Ref: TM-T10921

    1mg
    Descontinuado
    2mg
    Descontinuado
    Produto descontinuado
  • JMV 2959

    CAS:
    <p>JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).</p>
    Fórmula:C30H32N6O2
    Cor e Forma:Solid
    Peso molecular:508.61

    Ref: TM-T11719L

    1mg
    Descontinuado
    2mg
    Descontinuado
    Produto descontinuado
  • Picumeterol

    CAS:
    <p>Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that can be used to improve lung function and reduce airway hyperreactivity in patients with asthma.</p>
    Fórmula:C21H29Cl2N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:426.38

    Ref: TM-T68129

    Produto descontinuado
  • Anti-GLP1R Antibody


    <p>Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.</p>
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-804

    1mg
    Descontinuado
    5mg
    Descontinuado
    Produto descontinuado
  • Patecibart

    CAS:
    <p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>
    Pureza:98%
    Cor e Forma:Liquid

    Ref: TM-T81538

    1mg
    Descontinuado
    5mg
    Descontinuado
    50mg
    Descontinuado
    Produto descontinuado
  • BX471 hydrochloride

    CAS:
    <p>BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.</p>
    Fórmula:C21H25Cl2FN4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:471.35

    Ref: TM-T14845

    Produto descontinuado
  • TAK-683

    CAS:
    <p>TAK-683: a full KISS1R agonist, IC50=170 pM; a nonapeptide metastin analog with human EC50=0.96 nM, rat EC50=1.6 nM.</p>
    Fórmula:C64H83N17O13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1298.45

    Ref: TM-TP2156L

    100mg
    Descontinuado
    500mg
    Descontinuado
    Produto descontinuado
  • Sarizotan

    CAS:
    <p>Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.</p>
    Fórmula:C22H21FN2O
    Cor e Forma:Solid
    Peso molecular:348.421

    Ref: TM-T40439

    Produto descontinuado
  • Goserelin acetate(65807-02-5 Free base)


    <p>Goserelin acetate (ICI-118630 acetate) is a naturally occurring decapeptide, a GnRH (gonadotropin releasing hormone) agonist that reduces the production of sex hormones (testosterone and estrogen) for the treatment of prostate cancer, breast cancer and endometriosis.</p>
    Pureza:99.77%
    Cor e Forma:Odour Solid

    Ref: TM-T36918L

    1mg
    Descontinuado
    5mg
    Descontinuado
    10mg
    Descontinuado
    25mg
    Descontinuado
    50mg
    Descontinuado
    100mg
    Descontinuado
    Produto descontinuado
  • TAK-448

    CAS:
    <p>TAK-448 (MVT-602), a potent KISS1R agonist, IC50: 460 pM, EC50: 632 pM, trialed for Prostate Cancer and Hypogonadism.</p>
    Fórmula:C58H80N16O14
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1225.36

    Ref: TM-TP1094

    1mg
    Descontinuado
    5mg
    Descontinuado
    Produto descontinuado
  • 4-Hydroxyatomoxetine

    CAS:
    <p>4-Hydroxyatomoxetine, an active metabolite of Atomoxetine, is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.</p>
    Fórmula:C17H21NO2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:271.35

    Ref: TM-T10145

    100mg
    Descontinuado
    500mg
    Descontinuado
    Produto descontinuado
  • GSK-3050002


    <p>GSK-3050002 (HGS-1035) is a humanized IgG1 antibody that targets and binds to CCL20. It holds potential for inflammation research. For isotype control, refer to Human IgG1 kappa, Isotype Control.</p>
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-766

    1mg
    Descontinuado
    5mg
    Descontinuado
    Produto descontinuado
  • 1-Oleoyl Lysophosphatidic Acid

    CAS:
    <p>1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.</p>
    Fórmula:C21H41O7P
    Cor e Forma:Solid
    Peso molecular:436.52

    Ref: TM-T36907

    22.91mM*1
    Descontinuado
    22.91mM*100
    Descontinuado
    22.91mM*2.5
    Descontinuado
    22.91mM*500
    Descontinuado
    Produto descontinuado
  • 4-Hydroxypropranolol hydrochloride

    CAS:
    <p>4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).</p>
    Fórmula:C16H22ClNO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:311.8

    Ref: TM-T10150

    100mg
    Descontinuado
    500mg
    Descontinuado
    Produto descontinuado
  • Amelubant

    CAS:
    <p>Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.</p>
    Fórmula:C33H34N2O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:538.63

    Ref: TM-T14210

    100mg
    Descontinuado
    500mg
    Descontinuado
    Produto descontinuado
  • CRTh2 antagonist 3

    CAS:
    <p>CRTh2 antagonist 3, a potent molecule, activates PDK1 (EC50=2μM, Kd=8.4μM) and may cause cardiovascular inflammation.</p>
    Fórmula:C19H20N2O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:356.44

    Ref: TM-T10890

    100mg
    Descontinuado
    500mg
    Descontinuado
    Produto descontinuado
  • Propiram fumarate HCl

    CAS:
    <p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>
    Fórmula:C16H25N3O·xClH
    Pureza:99.25%
    Cor e Forma:Soild

    Ref: TM-T28453L

    1mg
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  • 3-Hydroxybenzylamine

    CAS:
    <p>3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.</p>
    Fórmula:C7H9NO
    Cor e Forma:Solid
    Peso molecular:123.155

    Ref: TM-T124305

    Produto descontinuado
  • Vornorexant

    CAS:
    <p>Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.</p>
    Fórmula:C23H22FN7O2
    Cor e Forma:Solid
    Peso molecular:447.474

    Ref: TM-T39004

    Produto descontinuado
  • (R)-(-)-α-Methylhistamine dihydrochloride

    CAS:
    <p>R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.</p>
    Fórmula:C6H13Cl2N3
    Cor e Forma:Solid
    Peso molecular:198.09

    Ref: TM-T24698

    Produto descontinuado
  • dapitant

    CAS:
    <p>Dapitant, a non-peptide, selective antagonist of human NKI receptors, is representative of the 7,7,4-triarylperhydroisoindol-4-ols.</p>
    Fórmula:C37H39NO4
    Cor e Forma:Solid
    Peso molecular:561.71

    Ref: TM-T68049

    Produto descontinuado
  • Desmethyl cariprazine

    CAS:
    <p>Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).</p>
    Fórmula:C20H30Cl2N4O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:413.38

    Ref: TM-T15100

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  • BRL 15572

    CAS:
    <p>BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.</p>
    Fórmula:C25H27ClN2O
    Cor e Forma:Solid
    Peso molecular:406.95

    Ref: TM-T64501

    Produto descontinuado
  • (Rac)-Zevaquenabant

    CAS:
    <p>(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.</p>
    Fórmula:C25H21ClF3N5O2S
    Cor e Forma:Solid
    Peso molecular:547.98

    Ref: TM-T39074

    Produto descontinuado
  • Canagliflozin-d4

    CAS:
    <p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>
    Fórmula:C24H25FO5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:448.54

    Ref: TM-T10669

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  • AM-2232

    CAS:
    <p>AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.</p>
    Fórmula:C24H20N2O
    Pureza:99.37%
    Cor e Forma:Solid
    Peso molecular:352.43

    Ref: TM-T21450

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  • Pamoic acid

    CAS:
    <p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>
    Fórmula:C23H16O6
    Pureza:99.99%
    Cor e Forma:Fine Yellow Powder
    Peso molecular:388.37

    Ref: TM-T8353

    1ml*10 (DMSO)
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  • 2-Methyl-5-HT hydrochloride

    CAS:
    <p>2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>
    Fórmula:C11H15ClN2O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:226.7

    Ref: TM-T10075L2

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  • 2-Arachidonoylglycerol

    CAS:
    <p>In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand</p>
    Fórmula:C23H38O4
    Pureza:95%
    Cor e Forma:Liquid
    Peso molecular:378.55

    Ref: TM-T14011

    5mg
    Descontinuado
    26.4mM*100
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  • MEN11467

    CAS:
    <p>MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.</p>
    Fórmula:C38H40N4O3
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:600.75

    Ref: TM-T12000

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  • Imetit dihydrobromide

    CAS:
    <p>Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).</p>
    Fórmula:C6H12Br2N4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:332.06

    Ref: TM-T15565

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  • Flumexadol

    CAS:
    <p>Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.</p>
    Fórmula:C11H12F3NO
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:231.21

    Ref: TM-T11302

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  • GR 218,231

    CAS:
    <p>GR 218,231 is a selective antagonist of D3 dopamine receptor.</p>
    Fórmula:C24H33NO3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:415.59

    Ref: TM-T27431

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  • Neurokinin antagonist 1

    CAS:
    <p>Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.</p>
    Fórmula:C38H40N4O3
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:600.75

    Ref: TM-T10056

    1mg
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  • AEF0117

    CAS:
    <p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>
    Fórmula:C29H40O3
    Pureza:99.58%
    Cor e Forma:Solid
    Peso molecular:436.63

    Ref: TM-T79909

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  • S1P1 agonist 6

    CAS:
    <p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>
    Fórmula:C25H26F3NO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:445.47

    Ref: TM-T79816

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  • 2-MNG

    CAS:
    <p>2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.</p>
    Fórmula:C8H8N2O3S
    Cor e Forma:Liquid
    Peso molecular:212.23

    Ref: TM-T89029

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  • Dimethandrolone Undecanoate

    CAS:
    <p>Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.</p>
    Fórmula:C31H50O3
    Pureza:99.65% - >99.99%
    Cor e Forma:Solid
    Peso molecular:470.73

    Ref: TM-T27176

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