GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.948 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(409 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5373 produtos de "GPCR/Proteína-G"
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WIN 62577
CAS:<p>WIN 62577 is a species-selective tachykinin NK1 receptor antagonist and also serves as an allosteric enhancer with micromolar potency at M3 receptors. Additionally, WIN 62577 demonstrates potent antiviral activity against SARS-CoV-2.</p>Fórmula:C29H31N3OCor e Forma:SolidPeso molecular:437.576LY 215840
CAS:<p>5-HT2/5-HT7 receptor antagonist</p>Fórmula:C24H33N3O2Pureza:98%Cor e Forma:SolidPeso molecular:395.54Ro-24-4736
CAS:<p>Ro 24-4736 is an effective and selective platelet-activating factor antagonist.</p>Fórmula:C31H20ClN5OSPureza:98%Cor e Forma:SolidPeso molecular:546.04Serlopitant
CAS:<p>Serlopitant is a selective antagonist of Neurokinin-1 (NK-1) receptor.</p>Fórmula:C29H28F7NO2Cor e Forma:SolidPeso molecular:555.53L-97-1
CAS:<p>L-97-1 is an antagonist of the adenosine A1 receptor.</p>Fórmula:C29H38N6O3Pureza:98%Cor e Forma:SolidPeso molecular:518.65Butopamine hydrochloride
CAS:<p>Butopamine hydrochloride is an orally active inotropic compound that is more effective at increasing heart rate compared to Dobutamine.</p>Fórmula:C18H24ClNO3Cor e Forma:SolidPeso molecular:337.84CBR Agonist-1
<p>CBR Agonist-1 targets CB1R and CB2R with Ki of 0.18 μM and 1.22 μM, useful for studying cannabinoid-related diseases.</p>Fórmula:C27H27FN4OCor e Forma:SolidPeso molecular:442.53MK-0812
CAS:<p>MK-0812 is a dual antagonist of the CCR2 and CCR5 receptors that can alleviate adipose inflammation in ob/ob mice.</p>Fórmula:C24H34F3N3O3Pureza:98%Cor e Forma:SolidPeso molecular:469.54PF-4693627
CAS:<p>PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM).</p>Fórmula:C26H29Cl2N3O3Pureza:98%Cor e Forma:SolidPeso molecular:502.43INCB-9471 dihydrochloride
CAS:<p>INCB-9471 HCl: a potent CCR5 antagonist, blocks monocyte migration & HIV-1.</p>Fórmula:C30H42Cl2F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:632.59RS 12254
CAS:<p>RS 12254 is a dopamine agonist and antihypertensive agent.</p>Fórmula:C28H40N2O4Pureza:98%Cor e Forma:SolidPeso molecular:468.63Opipramol dihydrochloride
CAS:<p>Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) primarily functioning as a sigma (σ) receptor agonist. It interacts effectively with sigma recognition sites, having a Ki value of 50 nM. Opipramol is applicable in the study of generalized anxiety disorder (GAD).</p>Fórmula:C23H31Cl2N3OCor e Forma:SolidPeso molecular:436.418PAR4 antagonist 3
CAS:<p>PAR4 antagonist3 (Compound 36) is a selective antagonist of protease-activated receptor 4 (PAR4). It exhibits antiplatelet activity with an IC50 of 26.1 nM and enhances metabolic stability in human liver microsomes, with a half-life (T1/2) of 97.6 minutes.</p>Fórmula:C22H16FN3O5SPeso molecular:453.44AA 497 (Free Base)
CAS:<p>AA 497, a beta-2 agonist, causes relaxation and suppresses Ca spike frequency.</p>Fórmula:C14H21NO3Pureza:98%Cor e Forma:SolidPeso molecular:251.32SAR-150640
CAS:SAR-150640, a selective β3-adrenergic receptor agonist, prevents an increase in MMP activity and production observed after LPS stimulation or in cases of chorioamnionitis.Fórmula:C25H35ClN2O7SCor e Forma:SolidPeso molecular:543.07NK1 receptor antagonist 2
CAS:<p>NK1 Receptor Antagonist 2, a compound targeting the NK1 receptor, holds potential for tinnitus and hearing loss research.</p>Fórmula:C31H35F7N4O2Cor e Forma:SolidPeso molecular:628.62Tipindole
CAS:<p>Tipindole is a serotonin antagonist utilized in research related to depression.</p>Fórmula:C16H20N2O2SCor e Forma:SolidPeso molecular:304.41RBM10-8
CAS:<p>RBM10-8 irreversibly inhibits human sphingosine-1- phosphate lyase (hS1PL) while behaving also as an enzyme substrate.</p>Fórmula:C17H36NO5PCor e Forma:SolidPeso molecular:365.45UK-432097
CAS:<p>UK 432097 is an adenosine A2A agonist.</p>Fórmula:C40H47N11O6Cor e Forma:SolidPeso molecular:777.87BIIE-0246 HCl
CAS:<p>BIIE-0246: A potent, non-peptide Y2 receptor antagonist; >650-fold more selective than Y1, Y4, Y5.</p>Fórmula:C49H59Cl2N11O6Cor e Forma:SolidPeso molecular:968.97AL 8810
CAS:<p>AL-8810 is an 11β-fluoro analog of PGF 2α with selective antagonist effects at the PGF 2α receptor (FP receptor) [1].</p>Fórmula:C24H31FO4Cor e Forma:SolidPeso molecular:402.5ZK118182 isopropyl ester
CAS:<p>ZK118182 isopropyl ester is a PG analog with potent DP-agonist activity (EC50 = 16.5 nM) and high affinity for the DP receptor (Ki = 74 nM).</p>Fórmula:C23H37ClO5Pureza:98%Cor e Forma:SolidPeso molecular:428.99A2A receptor antagonist 2
<p>A2A receptor antagonist 2 is a highly selective and potent antagonist of the adenosine A2Areceptor (IC50: 8.3 nM).</p>Fórmula:C25H28FN7O3Cor e Forma:SolidPeso molecular:493.53GnRH-R antagonist 1
CAS:<p>Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.</p>Fórmula:C31H28F5N7O6SPureza:98%Cor e Forma:SolidPeso molecular:721.65Taranabant
CAS:<p>Taranabant: potent CB1 receptor inverse agonist; inhibits agonists with 0.13 nM Ki in vitro.</p>Fórmula:C27H25ClF3N3O2Pureza:99.06% - 99.06%Cor e Forma:SolidPeso molecular:515.96CP-608039
CAS:<p>CP-608039 is a selective adenosine A3 receptor agonist for both human A3 and human A1 receptors.</p>Fórmula:C23H25ClN8O5Cor e Forma:SolidPeso molecular:528.95ONO-9780307
CAS:<p>ONO-9780307 is a specific antagonist of LPA1 (lysophosphatidic acid receptor 1) (IC50: 2.7 nM).</p>Fórmula:C30H35NO7Cor e Forma:SolidPeso molecular:521.6U92016A hydrochloride
CAS:<p>U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.</p>Fórmula:C19H26ClN3Cor e Forma:SolidPeso molecular:331.89GPBAR1-IN-3
CAS:<p>GPBAR1-IN-3 (Compound 14) is both a selective agonist for GPBAR1, with an EC50 value of 0.17 μM, and an antagonist for CysLT1R [1].</p>Fórmula:C21H23NO2Cor e Forma:SolidPeso molecular:321.41RF9 hydrochloride
<p>RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).</p>Fórmula:C26H39ClN6O3Cor e Forma:SolidPeso molecular:519.08Tiprenolol hydrochloride
CAS:<p>Tiprenolol hydrochloride is a β-adrenoceptor (β-adrenoceptor) antagonist. This compound is effective in eliminating ventricular arrhythmias in dogs caused by intravenous administration of adrenaline, following inhalation of halothane.</p>Fórmula:C13H22ClNO2SCor e Forma:SolidPeso molecular:291.84TM38837
CAS:<p>CB1 antagonist 4 is an inverse agonist of cannabinoid receptor 1 (CB1) with an IC50 of 0.4 nM. It can reduce body weight, improve plasma inflammatory markers, and enhance glucose homeostasis [1].</p>Fórmula:C27H20Cl2F3N7OCor e Forma:SolidPeso molecular:586.40ASN-1377642
CAS:<p>ASN-1377642 is an NK1 receptor antagonist with a Ki value of 251 nM. It demonstrates antitumor activity in breast cancer cells with high expression of NK1R-Tr.</p>Fórmula:C21H16ClN5OSCor e Forma:SolidPeso molecular:421.90HU 433
CAS:<p>HU 433, a synthetic cannabinoid, acts as a CB2 receptor agonist and is an enantiomer of HU 308. It provides anti-inflammatory and neuroprotective effects by binding to the CB2 receptor, primarily found on immune cells, thereby modulating immune responses and inflammation. Additionally, HU 433 influences microglial signaling pathways, particularly LPS and IFNγ-mediated routes, affecting the phosphorylation of MAPKs, including ERK1/2, JNK, p38, and Akt. This compound is valuable in researching neuroinflammation and retinal diseases.</p>Fórmula:C27H42O3Cor e Forma:SolidPeso molecular:414.62(2R,3S)-Azelaprag
CAS:<p>(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist</p>Fórmula:C25H29N7O4SPureza:97.47% - >99.99%Cor e Forma:SoildPeso molecular:523.61SSTR4 agonist 4
CAS:<p>SSTR4 agonist 4, potent in pain research, shows promise in rodent pain models, with potential for Alzheimer's due to hippocampus activity.</p>Fórmula:C19H26N4OCor e Forma:SolidPeso molecular:326.44Mafoprazine
CAS:<p>Mafoprazine, a phenylpiperazine derivative, exhibits varying affinities for neuronal receptors, primarily exerting its antipsychotic effects through blocking D2 receptors and enhancing α-adrenergic activity. It also increases the activity of dopamine metabolites.</p>Fórmula:C22H28FN3O3Cor e Forma:SolidPeso molecular:401.47BW A868C
CAS:BW A868C is a potent, selective PGD2 antagonist and a BW245C analogue, inert to other prostaglandin receptors.Fórmula:C25H37N3O5Cor e Forma:SolidPeso molecular:459.58Mrgx2 antagonist-3
CAS:<p>Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of the MrgX2 receptor, with an IC50 range of 0.042-2.5 nM. It blocks downstream G protein signaling and β-arrestin recruitment, inhibiting Mrgx2 receptor-mediated calcium influx and cell degranulation. Mrgx2 antagonist-3 shows potential for research in inflammation-associated diseases and pruritus, such as chronic urticaria and allergic asthma.</p>Fórmula:C15H15F2N3OCor e Forma:SolidPeso molecular:291.30YNT-3708
CAS:<p>YNT-3708 is an orexin receptor (OXR) agonist, exhibiting EC50 values of 14.6 nM for OX1R and 277 nM for OX2R.</p>Fórmula:C35H36N4O6SCor e Forma:SolidPeso molecular:640.749PF-9404C
CAS:<p>PF-9404C: S-S diastereoisomer, beta-blocker with vasodilation, boosts cyclic GMP in rat aorta cells from 3 to 53 pmol/mg protein.</p>Fórmula:C16H25N3O9Pureza:98%Cor e Forma:SolidPeso molecular:403.38GRK6-IN-5
CAS:<p>GRK6-IN-5 is an inhibitor of the GRK6 polypeptide, with an IC50 of 4.48 μM. GRK6-IN-5 is utilized in research focused on hematological malignancies, inflammatory diseases, and autoimmune disorders.</p>Fórmula:C23H21N3O2Cor e Forma:SolidPeso molecular:371.432MRGPRX2 modulator-1
CAS:<p>MRGPRX2 modulator-1 (example 17), a modulator of the mas-related G-protein receptor X2 (MRGPRX2), is employed in studies focused on inflammation, pain, and autoimmune disorders [1].</p>Fórmula:C20H19F6N5OCor e Forma:SolidPeso molecular:459.39APJ receptor agonist 8
CAS:<p>APJ receptor agonist 8 is a small molecule agonist of the APJ receptor, enhancing load-independent cardiac contractility in isolated perfused rat hearts.</p>Fórmula:C24H27N7O5SPureza:98.31% - 99.60%Cor e Forma:SolidPeso molecular:525.58Aeruginosin 98-B
CAS:<p>Aeruginosin 98-B, a protease inhibitor, effectively inhibits trypsin, plasmin, and thrombin with IC50 values of 0.6, 7.0, and 10.0 μg/mL, respectively.</p>Fórmula:C29H46N6O9SCor e Forma:SolidPeso molecular:654.78Ersentilide
CAS:<p>Ersentilide, a benzamide derivative, functions as both a β1-adrenergic receptor antagonist and an Ikr blocker. It has demonstrated efficacy in animal models of cardiac arrhythmias.</p>Fórmula:C21H26N4O5SCor e Forma:SolidPeso molecular:446.52Sulfinalol hydrochloride
CAS:<p>Sulfinalol hydrochloride is an orally active β-adrenoceptor (β-adrenoceptor) antagonist that exhibits direct vasodilatory activity. It is also classified as an antihypertensive agent.</p>Fórmula:C20H28ClNO4SCor e Forma:SolidPeso molecular:413.96Alixorexton
CAS:<p>Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.</p>Fórmula:C21H30N2O5SCor e Forma:SolidPeso molecular:422.538Elzasonan hydrochloride
CAS:<p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>Fórmula:C22H24Cl3N3OSCor e Forma:SolidPeso molecular:484.87RS 61756-007
CAS:<p>RS 61756-007 is a selective thromboxane receptor (TP) agonist.</p>Fórmula:C23H28O5Pureza:98%Cor e Forma:SolidPeso molecular:384.47LY 245769
CAS:<p>LY 245769 is an inhibitor of leukotriene E4 (LTE4).</p>Fórmula:C25H33F3N8OSPureza:98%Cor e Forma:SolidPeso molecular:550.64Leukotriene B4 dimethyl amide
CAS:<p>LTB4 dimethyl amide: inhibits human neutrophil degranulation and rat lysozyme release; antagonizes LTB4 receptor on guinea pig lung membranes (Ki = 130 nM).</p>Fórmula:C22H37NO3Cor e Forma:SolidPeso molecular:363.53UTPγS trisodium salt
CAS:<p>P2Y2 and P2Y4 receptor agonist</p>Fórmula:C9H12N2Na3O14P3SPureza:98%Cor e Forma:SolidPeso molecular:566.152,3-dinor-11β-Prostaglandin F2α
CAS:<p>2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where</p>Fórmula:C18H30O5Cor e Forma:SolidPeso molecular:326.43SB 258741 hydrochloride
<p>SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].</p>Fórmula:C19H31ClN2O2SCor e Forma:SolidPeso molecular:386.98MRS2179 tetrasodium hydrate
<p>MRS2179 blocks turkey P2Y1 receptor (Kb 102 nM, pA2 6.99), affects platelet aggregation, and has varying IC50s on P2 receptors.</p>Fórmula:C11H15N5Na4O10P2Cor e Forma:SolidPeso molecular:576.21BAY-899
CAS:<p>BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.</p>Fórmula:C25H19F2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:459.45SORT1-IN-5
CAS:<p>SORT1-IN-5 (compound 3) is a SORT1 inhibitor capable of crossing the blood-brain barrier. The MSOH salt form of SORT1-IN-5 exhibits a certain degree of oral bioavailability.</p>Fórmula:C19H31NO6SCor e Forma:SolidPeso molecular:401.52D1R antagonist 1
CAS:<p>Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].</p>Fórmula:C22H26BrNO4Pureza:98%Cor e Forma:SolidPeso molecular:448.35Dinoxyline
CAS:<p>Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.</p>Fórmula:C15H13NO3Cor e Forma:SolidPeso molecular:255.27Teoprolol
CAS:<p>Teoprolol is a blocker of β-adrenergic receptor.</p>Fórmula:C23H30N6O4Pureza:98%Cor e Forma:SolidPeso molecular:454.52PAR-2-IN-2
CAS:<p>PAR-2-IN-2 (compound P-596) is an inhibitor of protease-activated receptor 2 (PAR-2), with an IC50 of 10.79 μM for SLIGKV and an IC50 greater than 200 μM for trypsin.</p>Fórmula:C25H20F3N5O2Cor e Forma:SolidPeso molecular:479.454MrgprX2 antagonist-6
<p>MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.</p>Fórmula:C24H23F3N6O3Cor e Forma:SolidPeso molecular:500.47CCR1 antagonist 13
CAS:<p>CCR1 antagonist13 is a selective small molecule antagonist of CCR1.</p>Fórmula:C25H27ClFN3O4Cor e Forma:SolidPeso molecular:487.95TAK-661
CAS:<p>TAK-661 is an inhibitor of eosinophil chemotaxis (eosinophil chemotaxis) that significantly alleviates late-phase bronchoconstriction while inhibiting the proliferation of eosinophils in bronchoalveolar lavage (BAL) and their infiltration into the airway walls.</p>Fórmula:C13H21N5O3SCor e Forma:SolidPeso molecular:327.40HU-308
CAS:<p>HU-308, a synthetic cannabinoid analogue, is a highly selective agonist of the CB2 receptor. It demonstrates an affinity for the CB2 receptor that is over 440 times greater than its affinity for the CB1 receptor, which are predominantly found in immune cells. This compound plays a crucial role in modulating the immunosuppressive effects of the endocannabinoid system (ECS). Additionally, HU-308 possesses anti-inflammatory and neuroprotective properties, and it regulates the function of microglia. Its potential applications include research into neuroinflammation and retinal diseases.</p>Fórmula:C27H42O3Cor e Forma:SolidPeso molecular:414.62CCR1 antagonist 11 hydrochloride
<p>Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.</p>Cor e Forma:SolidCVN766
CAS:<p>CVN766 is an orally active orexin 1 receptor antagonist with blood-brain permeability, demonstrating IC50 values of 8 nM for OX1R and >10 μM for OX2R. CVN766 can be used to study schizophrenia [1].</p>Fórmula:C20H21F3N8OCor e Forma:SolidPeso molecular:446.43Protease-Activated Receptor-1 antagonist 2
<p>Selective, orally active PAR-1 antagonist with an IC50 of 7 nM, potential for cardiovascular disease studies.</p>Cor e Forma:SolidApafant
CAS:<p>Apafant (WEB 2086) is a PAF antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.</p>Fórmula:C22H22ClN5O2SPureza:99.56%Cor e Forma:SolidPeso molecular:455.96Remlifanserin
CAS:Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).Fórmula:C24H29F2N3O2Cor e Forma:SolidPeso molecular:429.50(S)-YNT-3708
CAS:<p>(S)-YNT-3708 is the S-isomer of YNT-3708, demonstrating relatively low activity against OX1R and OX2R receptors, with EC50 values of 3595 nM and 1661 nM, respectively.</p>Fórmula:C35H36N4O6SCor e Forma:SolidPeso molecular:640.749Etoperidone
CAS:<p>Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).</p>Fórmula:C19H28ClN5OCor e Forma:SolidPeso molecular:377.91Org 274179-0
CAS:<p>Org 274179-0 is an effective allosteric antagonist of the thyroid-stimulating hormone (TSH) receptor, with an IC50 in the nanomolar range. It fully inhibits TSH (and TSI)-mediated activation of the TSH receptor with minimal impact on the efficacy of TSH. This compound can be utilized in studies of Graves' disease (GD).</p>Fórmula:C28H27F3N2O2Cor e Forma:SolidPeso molecular:480.521ATL444
CAS:<p>ATL444 is an adenosine receptor antagonist with affinity (Ki values) for rA1AR, rA2AAR, rA2BAR, and rA3AR of 7.0, 2.5, 61.8, and >1000 nM, respectively.</p>Fórmula:C17H19N5OCor e Forma:SolidPeso molecular:309.37Rivenprost
CAS:<p>Rivenprost, selective EP4 agonist (Ki: 0.7 nM), promotes bone growth, osteoblast differentiation, and aids wound healing.</p>Fórmula:C24H34O6SCor e Forma:SolidPeso molecular:450.59Oral antiplatelet agent 1
CAS:<p>Oral antiplatelet agent 1 is a potent antiplatelet agent with an IC50 of 2.94 μM in vitro.</p>Fórmula:C23H24N4O5SPureza:98%Cor e Forma:SolidPeso molecular:468.53AMG-369
CAS:<p>AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.</p>Fórmula:C26H22FN3O2SPureza:98.04% - 98.92%Cor e Forma:SolidPeso molecular:459.54ASP-2205
CAS:<p>ASP-2205, a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM), enhances the urethral closure reflex mediated by the genital nerve, thereby preventing urinary incontinence.</p>Fórmula:C19H28N2OCor e Forma:SolidPeso molecular:300.44AH22921
CAS:<p>AH22921 is an EP4 prostaglandin receptor antagonist with the ability to antagonize the activation of adenylyl cyclase by prostaglandins in CHO cells. It induces a rightward shift in the PGE? concentration-response curve in these cells, functioning as a non-competitive antagonist. AH22921 is selective for the EP4 receptor, inhibiting its activity in CHO cells without affecting the PGE? concentration-response curve in NPE cells that contain the EP2 receptor.</p>Fórmula:C29H35NO5Cor e Forma:SolidPeso molecular:477.59UR-AK49
CAS:<p>UR-AK49 (compound 11) is an agonist for the human histamine H1 and H2 receptors. It exhibits an EC50 of 23 nM in the GTPase assay involving hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. UR-AK49 is applicable in neurologically related research.</p>Fórmula:C16H27N5OCor e Forma:SolidPeso molecular:305.42Tipelukast
CAS:<p>Tipelukast (KCA 757), an oral drug for asthma research, blocks leukotrienes and fights inflammation and fibrosis.</p>Fórmula:C29H38O7SPureza:>99.99%Cor e Forma:SolidPeso molecular:530.67SGLT1/2-IN-8
CAS:<p>SGLT1/2-IN-8 (compound 8) is a potent and orally active dual inhibitor of SGLT1/2, exhibiting IC50 values of 4 nM and 1 nM, respectively. It shows antihyperglycemic properties, making it suitable for related research.</p>Fórmula:C22H26O6Cor e Forma:SolidPeso molecular:386.438MDA77
CAS:<p>MDA77 is a CB2 agonist with an EC50 value of 5.82 nM and exhibits no activity towards CB1.</p>Fórmula:C21H23N3O3Cor e Forma:SolidPeso molecular:365.43SGLT1/2-IN-1
CAS:<p>SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor.</p>Fórmula:C25H28O8Cor e Forma:SolidPeso molecular:456.48Tebideutorexant
CAS:<p>Tebideutorexant, an orexin-1 receptor antagonist, shows anti-panic effects in rodents and humans, providing a tool for stress response and psychiatric research.</p>Fórmula:C23H16D2F4N4O2Pureza:98.89%Cor e Forma:SolidPeso molecular:460.42Aplaviroc
CAS:<p>Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.</p>Fórmula:C33H43N3O6Pureza:97.98% - 98.26%Cor e Forma:SolidPeso molecular:577.71RGH-122
CAS:<p>RGH-122 (compound 43), characterized as an orally active, potent, and selective hV1a receptor antagonist, demonstrates significant affinity with a K i value of 0.3 nM and an IC 50 of 0.9 nM. It exhibits microsomal stability, indicated by a CL int value of 13/28/25 μL/min/mg [1].</p>Fórmula:C24H25ClN4O3Cor e Forma:SolidPeso molecular:452.93CCR5 antagonist 1
CAS:<p>CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.</p>Fórmula:C39H46ClF2N5O3SPureza:98%Cor e Forma:SolidPeso molecular:738.33BI 639667
CAS:BI 639667, an azaindazole-class compound, potently inhibits CCR1 (IC50=1.8 nM in calcium flux assays).Fórmula:C22H18FN5O3SPureza:99.86%Cor e Forma:SolidPeso molecular:451.47Cendifensine
CAS:<p>Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).</p>Fórmula:C14H17Cl2NOCor e Forma:SolidPeso molecular:286.197GRK6-IN-4
CAS:<p>GRK6-IN-4 is an inhibitor of G protein-coupled receptor kinase 6 (GRK6) with an IC50 value of 1.56 μM. GRK6-IN-4 is applicable for research related to hematological malignancies, inflammatory diseases, and autoimmune disorders.</p>Fórmula:C15H15N5Cor e Forma:SolidPeso molecular:265.313BMS-741672
CAS:<p>BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.</p>Fórmula:C25H33F3N6O2Cor e Forma:SolidPeso molecular:506.56MSX-3
CAS:<p>MSX-3 is an antagonist of the A2A adenosine receptor and a prodrug of MSX-2.</p>Fórmula:C21H23N4Na2O7PPureza:98%Cor e Forma:SolidPeso molecular:520.389PF-07054894
CAS:<p>PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.</p>Fórmula:C24H30N6O4Cor e Forma:SolidPeso molecular:466.53Protease-Activated Receptor-1 antagonist 1
<p>Compound 13 is a PAR-1 antagonist with a 3 nM IC50, useful for thrombosis and heart disease research.</p>Fórmula:C25H24F2N2O3Cor e Forma:SolidPeso molecular:438.47Monlunabant
CAS:<p>Monlunabant ((S)-MRI-1891), a solid dispersion compound, functions as an inhibitor of the cannabinoid CB1 receptor [1].</p>Fórmula:C26H22ClF3N6O3SPureza:98%Cor e Forma:SolidPeso molecular:591.00BAY 38-7271
CAS:<p>BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) & 5.96 nM (CB2).</p>Fórmula:C20H21F3O5SPureza:98%Cor e Forma:SolidPeso molecular:430.44UNC10099984A
CAS:<p>UNC10099984A (Compound 6) is a functionally selective ligand for the dopamine D2 receptor, exhibiting a Ki value of 4.6 nM and an EC50 of 6.2 nM for β-arrestin. This compound is useful for research into central nervous system diseases related to the D2 receptor.</p>Fórmula:C24H29Cl2N3O2Cor e Forma:SolidPeso molecular:462.41CCG258208
CAS:<p>GRKs-IN-1 has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).</p>Fórmula:C24H25FN4O4Pureza:98%Cor e Forma:SolidPeso molecular:452.48AChE/BChE-IN-21
CAS:<p>AChE/BChE-IN-21 is an antagonist of the histamine H3 receptor, a calcium channel blocker, and an acetylcholinesterase inhibitor. It exhibits neuroprotective activities against H2O2 and Aβ1-40, and can restore cognitive functions in AD mice.</p>Fórmula:C38H54N4O4Cor e Forma:SolidPeso molecular:630.86Rodatristat ethyl
CAS:<p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.</p>Fórmula:C29H31ClF3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:590.04Iralukast (CGP 45715A)
CAS:<p>Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.</p>Fórmula:C38H37F3O8SCor e Forma:SolidPeso molecular:710.76EP-3945
CAS:<p>EP-3945 is an agonist of Mas-related G protein-coupled receptors (MRGPR), exhibiting greater potency than the small molecule agonist β-Alanine targeting MRGPRD. MRGPRs play a crucial role in inflammatory itch and pain perception. These receptors interact with Gq (MRGPRX2, MRGPRX4, and MRGPRX1 are coupled with Gq; MRGPRX2 and MRGPRD couple with Gi), with EP-3945 having an EC50 value of 211.6 nM for Gq.</p>Fórmula:C24H26N4O3Cor e Forma:SolidPeso molecular:418.488F 14679
CAS:<p>F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.</p>Fórmula:C21H25ClF2N4OPureza:99.09%Cor e Forma:SolidPeso molecular:422.9GLP-1 receptor agonist 11
CAS:<p>GLP-1 Receptor Agonist 11 (compound 3) acts as an effective agonist for the GLP Receptor, finding use in research related to conditions like diabetes and non-alc. fatty liver disease [1].</p>Fórmula:C31H31ClFN3O4Cor e Forma:SolidPeso molecular:564.05Tonapofylline
CAS:<p>Tonapofylline, orally active, selectively blocks A1 adenosine receptor (Ki: 7.4 nM), used in heart failure research.</p>Fórmula:C22H32N4O4Pureza:98.57%Cor e Forma:SolidPeso molecular:416.51LB-102
CAS:<p>LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.</p>Fórmula:C18H29N3O4SCor e Forma:SolidPeso molecular:383.51BMS-986141
CAS:<p>BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614</p>Fórmula:C27H23N5O5S2Pureza:98.43% - 99.26%Cor e Forma:SolidPeso molecular:561.63BQ-788
CAS:<p>BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.</p>Fórmula:C34H51N5O7Pureza:98.81%Cor e Forma:SolidPeso molecular:641.8SB-423562
CAS:<p>SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.</p>Fórmula:C26H32N2O4Pureza:99.22%Cor e Forma:SolidPeso molecular:436.54Vofopitant
CAS:<p>Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).</p>Fórmula:C21H23F3N6OPureza:97.86%Cor e Forma:SolidPeso molecular:432.44Dersimelagon
CAS:<p>Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.</p>Fórmula:C36H45F4N3O5Pureza:97.35% - 98.23%Cor e Forma:SolidPeso molecular:675.75SB-224289 hydrochloride
CAS:<p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>Fórmula:C32H33ClN4O3Pureza:97.82% - 98.99%Cor e Forma:SolidPeso molecular:557.08LSN3318839
CAS:<p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>Fórmula:C26H23Cl2N3O2Pureza:99.21%Cor e Forma:SolidPeso molecular:480.39AZD-5672
CAS:<p>AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.</p>Fórmula:C32H38F2N2O5S2Pureza:98.1%Cor e Forma:SolidPeso molecular:632.78Vofopitant dihydrochloride
CAS:Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.Fórmula:C21H25Cl2F3N6OPureza:98.99%Cor e Forma:SolidPeso molecular:505.36AZD5462
CAS:<p>AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.</p>Fórmula:C30H41FN2O6Pureza:98.32% - 99.63%Cor e Forma:SolidPeso molecular:544.65PF-07258669
CAS:<p>PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.</p>Fórmula:C25H27FN6O2Pureza:99.9%Cor e Forma:SolidPeso molecular:462.52Treprostinil diethanolamine
CAS:<p>Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,</p>Fórmula:C27H45NO7Pureza:99.86%Cor e Forma:SolidPeso molecular:495.65Rolapitant hydrochloride
CAS:<p>Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki of 0.66 nM.</p>Fórmula:C25H27ClF6N2O2Pureza:98.35% - 99.79%Cor e Forma:SolidPeso molecular:536.94(Rac)-Rotigotine hydrochloride
CAS:<p>(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.</p>Fórmula:C19H26ClNOSCor e Forma:SolidPeso molecular:351.93SHA 68
CAS:<p>SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR) with IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107.</p>Fórmula:C26H24FN3O3Pureza:98%Cor e Forma:SolidPeso molecular:445.49Arotinolol
CAS:<p>Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.</p>Fórmula:C15H21N3O2S3Cor e Forma:White SolidPeso molecular:371.54Pumosetrag Hydrochloride
CAS:<p>Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.</p>Fórmula:C15H18ClN3O2SPureza:98%Cor e Forma:SolidPeso molecular:339.84HOKU-81
CAS:<p>HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.</p>Fórmula:C12H18ClNO2Cor e Forma:SolidPeso molecular:243.737-Desmethyl-agomelatine
CAS:<p>7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.</p>Fórmula:C14H15NO2Cor e Forma:SolidPeso molecular:229.27ML-00253764 hydrochloride
CAS:<p>ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).</p>Fórmula:C18H19BrClFN2OCor e Forma:SolidPeso molecular:413.71ML-290
CAS:<p>ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.</p>Fórmula:C24H21F3N2O5SCor e Forma:SolidPeso molecular:506.49CYM 9484
CAS:CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.Fórmula:C27H31N3O3S2Cor e Forma:SolidPeso molecular:509.68Protease-Activated Receptor-4
CAS:<p>Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.</p>Fórmula:C33H46N8O7Pureza:98%Cor e Forma:SolidPeso molecular:666.77Metipranolol hydrochloride
CAS:<p>Metipranolol hydrochloride is a non-selective β-adrenergic receptor blocking agent.</p>Fórmula:C17H28ClNO4Pureza:98%Cor e Forma:SolidPeso molecular:345.86SB-399885 hydrochloride
CAS:SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.Fórmula:C18H22Cl3N3O4SPureza:98%Cor e Forma:SolidPeso molecular:482.81BIBP3226 TFA
CAS:<p>BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).</p>Fórmula:C29H32F3N5O5Cor e Forma:SolidPeso molecular:587.59JMV 2959
CAS:JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).Fórmula:C30H32N6O2Cor e Forma:SolidPeso molecular:508.61SR 146131
CAS:<p>SR 146131 is a potent and selective agonist of the nonpeptide receptor.</p>Fórmula:C32H36ClN3O5SPureza:98%Cor e Forma:SolidPeso molecular:610.16Beraprost sodium
CAS:Beraprost sodium is a stable and orally active prodrug of PGI2.Fórmula:C24H29NaO5Cor e Forma:SolidPeso molecular:420.481BRL 15572
CAS:<p>BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.</p>Fórmula:C25H27ClN2OCor e Forma:SolidPeso molecular:406.95(Rac)-Zevaquenabant
CAS:<p>(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.</p>Fórmula:C25H21ClF3N5O2SCor e Forma:SolidPeso molecular:547.98(R)-(-)-α-Methylhistamine dihydrochloride
CAS:<p>R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.</p>Fórmula:C6H13Cl2N3Cor e Forma:SolidPeso molecular:198.09Goserelin acetate(65807-02-5 Free base)
<p>Goserelin acetate （ICI-118630 acetate） is a naturally occurring decapeptide, a GnRH (gonadotropin releasing hormone) agonist that reduces the production of sex hormones (testosterone and estrogen) for the treatment of prostate cancer, breast cancer and endometriosis.</p>Pureza:99.77%Cor e Forma:Odour SolidVornorexant
CAS:<p>Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.</p>Fórmula:C23H22FN7O2Cor e Forma:SolidPeso molecular:447.474TAK-448
CAS:<p>TAK-448 (MVT-602), a potent KISS1R agonist, IC50: 460 pM, EC50: 632 pM, trialed for Prostate Cancer and Hypogonadism.</p>Fórmula:C58H80N16O14Pureza:98%Cor e Forma:SolidPeso molecular:1225.36dapitant
CAS:<p>Dapitant, a non-peptide, selective antagonist of human NKI receptors, is representative of the 7,7,4-triarylperhydroisoindol-4-ols.</p>Fórmula:C37H39NO4Cor e Forma:SolidPeso molecular:561.71GSK-3050002
<p>GSK-3050002 (HGS-1035) is a humanized IgG1 antibody that targets and binds to CCL20. It holds potential for inflammation research. For isotype control, refer to Human IgG1 kappa, Isotype Control.</p>Cor e Forma:Odour Liquid4-Hydroxypropranolol hydrochloride
CAS:<p>4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).</p>Fórmula:C16H22ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:311.8Desmethyl cariprazine
CAS:<p>Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).</p>Fórmula:C20H30Cl2N4OPureza:98%Cor e Forma:SolidPeso molecular:413.38Anti-GLP1R Antibody
<p>Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.</p>Cor e Forma:Odour LiquidAmelubant
CAS:<p>Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.</p>Fórmula:C33H34N2O5Pureza:98%Cor e Forma:SolidPeso molecular:538.63TAK-683
CAS:<p>TAK-683: a full KISS1R agonist, IC50=170 pM; a nonapeptide metastin analog with human EC50=0.96 nM, rat EC50=1.6 nM.</p>Fórmula:C64H83N17O13Pureza:98%Cor e Forma:SolidPeso molecular:1298.45BX471 hydrochloride
CAS:<p>BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.</p>Fórmula:C21H25Cl2FN4O3Pureza:98%Cor e Forma:SolidPeso molecular:471.35CRTh2 antagonist 3
CAS:<p>CRTh2 antagonist 3, a potent molecule, activates PDK1 (EC50=2μM, Kd=8.4μM) and may cause cardiovascular inflammation.</p>Fórmula:C19H20N2O3SPureza:98%Cor e Forma:SolidPeso molecular:356.444-Hydroxyatomoxetine
CAS:<p>4-Hydroxyatomoxetine, an active metabolite of Atomoxetine, is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.</p>Fórmula:C17H21NO2Pureza:98%Cor e Forma:SolidPeso molecular:271.35Propiram fumarate HCl
CAS:<p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>Fórmula:C16H25N3O·xClHPureza:99.25%Cor e Forma:SoildPicumeterol
CAS:<p>Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that can be used to improve lung function and reduce airway hyperreactivity in patients with asthma.</p>Fórmula:C21H29Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:426.381-Oleoyl Lysophosphatidic Acid
CAS:<p>1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.</p>Fórmula:C21H41O7PCor e Forma:SolidPeso molecular:436.52Ref: TM-T36907
Produto descontinuadoSarizotan
CAS:<p>Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.</p>Fórmula:C22H21FN2OCor e Forma:SolidPeso molecular:348.421Patecibart
CAS:<p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>Pureza:98%Cor e Forma:Liquid3-Hydroxybenzylamine
CAS:<p>3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.</p>Fórmula:C7H9NOCor e Forma:SolidPeso molecular:123.155Canagliflozin-d4
CAS:<p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>Fórmula:C24H25FO5SPureza:98%Cor e Forma:SolidPeso molecular:448.54Ref: TM-T10669
Produto descontinuadoAM-2232
CAS:<p>AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.</p>Fórmula:C24H20N2OPureza:99.37%Cor e Forma:SolidPeso molecular:352.432-Methyl-5-HT hydrochloride
CAS:2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Fórmula:C11H15ClN2OPureza:98%Cor e Forma:SolidPeso molecular:226.7Pamoic acid
CAS:<p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>Fórmula:C23H16O6Pureza:99.99%Cor e Forma:Fine Yellow PowderPeso molecular:388.372-Arachidonoylglycerol
CAS:<p>In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand</p>Fórmula:C23H38O4Pureza:95%Cor e Forma:LiquidPeso molecular:378.55GR 218,231
CAS:<p>GR 218,231 is a selective antagonist of D3 dopamine receptor.</p>Fórmula:C24H33NO3SPureza:98%Cor e Forma:SolidPeso molecular:415.59Imetit dihydrobromide
CAS:<p>Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).</p>Fórmula:C6H12Br2N4SPureza:98%Cor e Forma:SolidPeso molecular:332.06Flumexadol
CAS:<p>Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.</p>Fórmula:C11H12F3NOPureza:98%Cor e Forma:SolidPeso molecular:231.21Neurokinin antagonist 1
CAS:<p>Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.</p>Fórmula:C38H40N4O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:600.75MEN11467
CAS:MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.Fórmula:C38H40N4O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:600.75AEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Fórmula:C29H40O3Pureza:99.58%Cor e Forma:SolidPeso molecular:436.63S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Fórmula:C25H26F3NO3Pureza:98%Cor e Forma:SolidPeso molecular:445.47Dimethandrolone Undecanoate
CAS:<p>Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.</p>Fórmula:C31H50O3Pureza:99.65% - >99.99%Cor e Forma:SolidPeso molecular:470.73Ref: TM-T27176
Produto descontinuado2-MNG
CAS:<p>2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.</p>Fórmula:C8H8N2O3SCor e Forma:LiquidPeso molecular:212.23
