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GPCR/Proteína-G

GPCR/Proteína-G

Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.

Subcategorias de "GPCR/Proteína-G"

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Foram encontrados 5352 produtos de "GPCR/Proteína-G"

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  • SR 140333

    CAS:
    <p>SR 140333 is a NK1 receptor antagonist.</p>
    Fórmula:C37H45Cl3N2O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:656.12
  • BNS808

    CAS:
    <p>BNS808 is an orally active, selective CB1R antagonist with an IC50 of 0.8 nM, demonstrating significant selectivity for CB2R and minimal brain penetration. It is being studied for the treatment of obesity and related metabolic complications, such as metabolic dysfunction-associated steatotic liver disease (MASLD). BNS808 reduces drug exposure to the central nervous system, enhancing safety, and minimizes drug interactions through high plasma protein binding.</p>
    Fórmula:C25H20Cl3N3O3S
    Cor e Forma:Solid
    Peso molecular:548.869
  • MED 27

    CAS:
    <p>MED 27 is an inhibitor of thromboxane synthase and thromboxane A2 receptors. It effectively inhibits rat platelet aggregation at doses significantly lower than those required for acetylsalicylic acid.</p>
    Fórmula:C24H25N5O5
    Cor e Forma:Solid
    Peso molecular:463.49
  • AAZ-A 154 mesylate

    CAS:
    <p>AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.</p>
    Fórmula:C15H24N2O4S
    Cor e Forma:Solid
    Peso molecular:328.43
  • AAZ-A 154

    CAS:
    <p>AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.</p>
    Fórmula:C14H20N2O
    Cor e Forma:Solid
    Peso molecular:232.32
  • SGL5213

    CAS:
    <p>SGL5213 is a potent oral SGLT1 inhibitor (IC50: 29 nM) with potential for treating type 2 diabetes.</p>
    Fórmula:C37H55N3O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:669.85
  • AAZ-A 154 benzoate

    CAS:
    <p>AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.</p>
    Fórmula:C21H26N2O3
    Cor e Forma:Solid
    Peso molecular:354.44
  • Pexacerfont

    CAS:
    <p>Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).</p>
    Fórmula:C18H24N6O
    Pureza:99.77%
    Cor e Forma:Solid
    Peso molecular:340.42
  • Protease-Activated Receptor-1 antagonist 3


    <p>PAR-1 antagonist 3: potent (IC50: 7 nM), binds hERG K+ channels (IC50: 9 μM).</p>
    Fórmula:C30H34N4O3
    Cor e Forma:Solid
    Peso molecular:498.62
  • Taprostene

    CAS:
    <p>Taprostene (CG-4203), a stable Prostacyclin analogue, protects endothelium and myocardium post-ischemia in cats, with minimal hemodynamic impact.</p>
    Fórmula:C24H30O5
    Cor e Forma:Solid
    Peso molecular:398.49
  • NCATS-SM4420

    CAS:
    <p>NCATS-SM4420 (Compound A35) is an orally effective ligand for the thyroid-stimulating hormone receptor (TSHR) that inhibits the proliferation of MDA-T32 and MDA-T85 cells both in vitro and in vivo, with IC50 values of 0.71 μM and 0.38 μM, respectively. Additionally, it suppresses the metastasis of MDA-T85F1 in mice. NCATS-SM4420 holds potential for research in the field of thyroid cancer.</p>
    Fórmula:C31H27N3O5
    Cor e Forma:Solid
    Peso molecular:521.56
  • Zafirlukast metabolite M1

    CAS:
    <p>Zafirlukast metabolite M1 (compound 15) is an inhibitor used in the treatment of asthma and other allergic pulmonary conditions, effectively antagonizing leukotriene activity.</p>
    Fórmula:C25H25N3O4S
    Cor e Forma:Solid
    Peso molecular:463.549
  • PF-06372222

    CAS:
    <p>PF-06372222: a small-molecule that modulates GCGR and antagonizes GLP-1R, affecting insulin and glucagon.</p>
    Fórmula:C26H28F3N5O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:515.53
  • (-)-5-HT2C agonist-3

    CAS:
    <p>Compound (−)-19, also known as (-)-5-HT2C agonist-3, is a selective 5-HT2C agonist exhibiting a preference for Gq signaling. It demonstrates efficiency with EC50 values for 5-HT2 receptor subtypes as follows: 5-HT2C at 103 nM, 5-HT2B at 570 nM, and 5-HT2A at 72 nM. This compound is utilized in research on antipsychotics.</p>
    Fórmula:C19H23ClFNO2
    Cor e Forma:Solid
    Peso molecular:351.84
  • A3AR antagonist 5

    CAS:
    <p>A3AR antagonist 5 (Compound 16) acts as a selective antagonist for the human adenosine A3 receptor (human adenosine A3 receptor), with an affinity expressed as a pC value of 4.542 μM.</p>
    Fórmula:C18H16N2O2S
    Cor e Forma:Solid
    Peso molecular:324.40
  • AAZ-A 154 hydrobromide

    CAS:
    <p>AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.</p>
    Fórmula:C14H21BrN2O
    Cor e Forma:Solid
    Peso molecular:313.23
  • AAZ-A 154 hydrochloride

    CAS:
    <p>AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.</p>
    Fórmula:C14H21ClN2O
    Cor e Forma:Solid
    Peso molecular:268.78
  • AMG-369

    CAS:
    <p>AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.</p>
    Fórmula:C26H22FN3O2S
    Pureza:98.04% - 98.92%
    Cor e Forma:Solid
    Peso molecular:459.54
  • Histamine H3 antagonist-1

    CAS:
    <p>Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].</p>
    Fórmula:C24H28F3N3O2
    Cor e Forma:Solid
    Peso molecular:447.49
  • TM38837

    CAS:
    <p>CB1 antagonist 4 is an inverse agonist of cannabinoid receptor 1 (CB1) with an IC50 of 0.4 nM. It can reduce body weight, improve plasma inflammatory markers, and enhance glucose homeostasis [1].</p>
    Fórmula:C27H20Cl2F3N7O
    Cor e Forma:Solid
    Peso molecular:586.40
  • Neladenoson

    CAS:
    <p>Neladenoson is an effective and selective agonist of the Adenosine A1 Receptor (A1R). EGFR-IN-162 shows potential for research in heart failure.</p>
    Fórmula:C29H24ClN5O2S2
    Cor e Forma:Solid
    Peso molecular:574.12
  • CCR1 antagonist 13

    CAS:
    <p>CCR1 antagonist13 is a selective small molecule antagonist of CCR1.</p>
    Fórmula:C25H27ClFN3O4
    Cor e Forma:Solid
    Peso molecular:487.95
  • HU 433

    CAS:
    <p>HU 433, a synthetic cannabinoid, acts as a CB2 receptor agonist and is an enantiomer of HU 308. It provides anti-inflammatory and neuroprotective effects by binding to the CB2 receptor, primarily found on immune cells, thereby modulating immune responses and inflammation. Additionally, HU 433 influences microglial signaling pathways, particularly LPS and IFNγ-mediated routes, affecting the phosphorylation of MAPKs, including ERK1/2, JNK, p38, and Akt. This compound is valuable in researching neuroinflammation and retinal diseases.</p>
    Fórmula:C27H42O3
    Cor e Forma:Solid
    Peso molecular:414.62
  • (2R,3S)-Azelaprag

    CAS:
    <p>(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist</p>
    Fórmula:C25H29N7O4S
    Pureza:97.47% - >99.99%
    Cor e Forma:Soild
    Peso molecular:523.61
  • CVN766

    CAS:
    <p>CVN766 is an orally active orexin 1 receptor antagonist with blood-brain permeability, demonstrating IC50 values of 8 nM for OX1R and &gt;10 μM for OX2R. CVN766 can be used to study schizophrenia [1].</p>
    Fórmula:C20H21F3N8O
    Cor e Forma:Solid
    Peso molecular:446.43
  • NBI 35965 hydrochloride

    CAS:
    <p>NBI 35965 hydrochloride is a selective CRF1 (corticotropin-releasing factor receptor 1) antagonist that is both orally active and capable of penetrating the brain. It possesses a K i value of 4 nM and a pK i of 8.5, and does not affect CRF2. This compound effectively diminishes CRF or stress-triggered ACTH (adrenocorticotropic hormone) production in vivo, demonstrating pIC 50 values of 7.1 and 6.9. Additionally, NBI 35965 hydrochloride exhibits anxiolytic properties [1] [2].</p>
    Fórmula:C21H23Cl3N4
    Cor e Forma:Solid
    Peso molecular:437.79
  • SSTR5 antagonist 6

    CAS:
    <p>SSTR5 antagonist 6, an orally active antagonist specific to the somatostatin receptor subtype 5 (SSTR5), exhibits an IC50 value of 24 nM. This compound is utilized in researching type 2 diabetes [1].</p>
    Fórmula:C22H28ClN3O4
    Cor e Forma:Solid
    Peso molecular:433.93
  • SJPYT-310

    CAS:
    <p>SJPYT-310 is a selective PXR antagonist, exhibiting no noticeable cytotoxicity.</p>
    Fórmula:C27H36N4O3
    Cor e Forma:Solid
    Peso molecular:464.6
  • Acyline

    CAS:
    <p>Acyline, a GnRH antagonist, suppresses gonadotropins and testosterone in animals and maintains the effect for 2 weeks in men with one dose.</p>
    Fórmula:C80H102ClN15O14
    Cor e Forma:Solid
    Peso molecular:1533.21
  • GLP-1 receptor agonist 11

    CAS:
    <p>GLP-1 Receptor Agonist 11 (compound 3) acts as an effective agonist for the GLP Receptor, finding use in research related to conditions like diabetes and non-alc. fatty liver disease [1].</p>
    Fórmula:C31H31ClFN3O4
    Cor e Forma:Solid
    Peso molecular:564.05
  • CB2R/5-HT1AR agonist 1

    CAS:
    <p>Compound 2o, also known as CB2R/5-HT1AR agonist 1, serves as a partial orally active agonist for the CB2 receptor (EC50 = 479.6 nM) and a full agonist for the 5-HT1A receptor (EC50 = 2.7 μM). This compound demonstrates both anti-anxiety and anti-depressive effects and has favorable pharmacokinetic properties [1].</p>
    Fórmula:C24H33NO3
    Cor e Forma:Solid
    Peso molecular:383.52
  • Tebideutorexant

    CAS:
    <p>Tebideutorexant, an orexin-1 receptor antagonist, shows anti-panic effects in rodents and humans, providing a tool for stress response and psychiatric research.</p>
    Fórmula:C23H16D2F4N4O2
    Pureza:98.89%
    Cor e Forma:Solid
    Peso molecular:460.42
  • Mrgx2 antagonist-3

    CAS:
    <p>Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of the MrgX2 receptor, with an IC50 range of 0.042-2.5 nM. It blocks downstream G protein signaling and β-arrestin recruitment, inhibiting Mrgx2 receptor-mediated calcium influx and cell degranulation. Mrgx2 antagonist-3 shows potential for research in inflammation-associated diseases and pruritus, such as chronic urticaria and allergic asthma.</p>
    Fórmula:C15H15F2N3O
    Cor e Forma:Solid
    Peso molecular:291.30
  • GRK6-IN-5

    CAS:
    <p>GRK6-IN-5 is an inhibitor of the GRK6 polypeptide, with an IC50 of 4.48 μM. GRK6-IN-5 is utilized in research focused on hematological malignancies, inflammatory diseases, and autoimmune disorders.</p>
    Fórmula:C23H21N3O2
    Cor e Forma:Solid
    Peso molecular:371.432
  • MRGPRX2 modulator-1

    CAS:
    <p>MRGPRX2 modulator-1 (example 17), a modulator of the mas-related G-protein receptor X2 (MRGPRX2), is employed in studies focused on inflammation, pain, and autoimmune disorders [1].</p>
    Fórmula:C20H19F6N5O
    Cor e Forma:Solid
    Peso molecular:459.39
  • BIBO3304 diTFA

    CAS:
    <p>BIBO3304 (diTFA), a selective neuropeptide Y (NPY) Y1 receptor antagonist, demonstrates oral efficacy. It exhibits high affinity for Y1 receptors in both humans and rats, with IC50 values of 0.38 nM and 0.72 nM, respectively. Additionally, BIBO3304 (diTFA) enhances bone-tendon healing via the Wnt/β-catenin signaling pathway [1] [2] [3].</p>
    Fórmula:C33H37F6N7O7
    Cor e Forma:Solid
    Peso molecular:757.68
  • Aeruginosin 98-B

    CAS:
    <p>Aeruginosin 98-B, a protease inhibitor, effectively inhibits trypsin, plasmin, and thrombin with IC50 values of 0.6, 7.0, and 10.0 μg/mL, respectively.</p>
    Fórmula:C29H46N6O9S
    Cor e Forma:Solid
    Peso molecular:654.78
  • Pareptide monohydrochloride

    CAS:
    <p>Pareptide monohydrochloride is a metabolically stable analog of melatonin inhibitor (MIF).</p>
    Fórmula:C14H27ClN4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:334.84
  • Protease-Activated Receptor-1 antagonist 1


    <p>Compound 13 is a PAR-1 antagonist with a 3 nM IC50, useful for thrombosis and heart disease research.</p>
    Fórmula:C25H24F2N2O3
    Cor e Forma:Solid
    Peso molecular:438.47
  • RU 52583

    CAS:
    <p>RU 52583 is an alpha 2-adrenergic receptor antagonist.</p>
    Fórmula:C18H20N2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:264.36
  • Befiradol hydrochloride

    CAS:
    <p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>
    Fórmula:C20H23Cl2F2N3O
    Pureza:99.1%
    Cor e Forma:Solid
    Peso molecular:430.32
  • Apafant

    CAS:
    <p>Apafant (WEB 2086) is a PAF antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.</p>
    Fórmula:C22H22ClN5O2S
    Pureza:99.56%
    Cor e Forma:Solid
    Peso molecular:455.96
  • A2A receptor antagonist 2


    <p>A2A receptor antagonist 2 is a highly selective and potent antagonist of the adenosine A2Areceptor (IC50: 8.3 nM).</p>
    Fórmula:C25H28FN7O3
    Cor e Forma:Solid
    Peso molecular:493.53
  • Disulergine

    CAS:
    <p>Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.</p>
    Fórmula:C17H24N4O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:348.46
  • CCR1 antagonist 11 hydrochloride


    <p>Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.</p>
    Cor e Forma:Solid
  • A1AR antagonist 1


    <p>Compound 18g, a potent A1AR blocker with Ki: 2.08 nM (hA1), 6.91 nM (hA2A), 31.2 nM (hA2B).</p>
    Fórmula:C18H14N4O
    Cor e Forma:Solid
    Peso molecular:302.33
  • Ophiobolin C

    CAS:
    <p>inhibitor of human CCR5 binding to HIV-1 gp120</p>
    Fórmula:C25H38O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:386.57
  • CS-003 Free base

    CAS:
    <p>CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats respiratory diseases.</p>
    Fórmula:C34H38Cl2N2O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:673.65
  • Burapitant

    CAS:
    <p>Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.</p>
    Fórmula:C31H35Cl2F6N3O3
    Pureza:>99.99% - >99.99%
    Cor e Forma:Solid
    Peso molecular:682.52
  • MSX-3

    CAS:
    <p>MSX-3 is an antagonist of the A2A adenosine receptor and a prodrug of MSX-2.</p>
    Fórmula:C21H23N4Na2O7P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:520.389
  • AA 497 (Free Base)

    CAS:
    <p>AA 497, a beta-2 agonist, causes relaxation and suppresses Ca spike frequency.</p>
    Fórmula:C14H21NO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:251.32
  • RGS10 modulator-1

    CAS:
    <p>RGS10 modulator-1 (compound 15) is an effective regulator of RGS10. It significantly reverses IFNγ-induced expression of both RGS10 protein and mRNA, as well as COX-2 mRNA and iNOS expression triggered by IFNγ.</p>
    Fórmula:C16H15BrN2O3S2
    Cor e Forma:Solid
    Peso molecular:427.336
  • ONO-9780307

    CAS:
    <p>ONO-9780307 is a specific antagonist of LPA1 (lysophosphatidic acid receptor 1) (IC50: 2.7 nM).</p>
    Fórmula:C30H35NO7
    Cor e Forma:Solid
    Peso molecular:521.6
  • U92016A hydrochloride

    CAS:
    <p>U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.</p>
    Fórmula:C19H26ClN3
    Cor e Forma:Solid
    Peso molecular:331.89
  • Beloxepin

    CAS:
    <p>Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.</p>
    Fórmula:C19H21NO2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:295.38
  • MK-3207 Hydrochloride

    CAS:
    <p>MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.</p>
    Fórmula:C31H30ClF2N5O3
    Pureza:98.19%
    Cor e Forma:Solid
    Peso molecular:594.05
  • LK 11

    CAS:
    <p>LK-11, an alkaloid derivative, inhibits the passive uptake of norepinephrine (NA) by synaptic vesicles in the thalamus, similarly to cocaine.</p>
    Fórmula:C15H26N2O3
    Cor e Forma:Solid
    Peso molecular:282.38
  • SphK1-IN-1


    <p>SphK1-IN-1: SphK1 ATPase inhibitor, IC50=2.48 μM, potential for cancer research.</p>
    Fórmula:C22H22N6O2
    Cor e Forma:Solid
    Peso molecular:402.45
  • Setomagpran

    CAS:
    <p>Setomagpran is an antagonist of the mas-related G protein-coupled receptor (MRGPR) and possesses anti-inflammatory properties.</p>
    Fórmula:C22H19Cl2F6N5O
    Cor e Forma:Solid
    Peso molecular:554.316
  • LX2761

    CAS:
    <p>LX2761 is a stable inhibitor for SGLT1/2 with IC50s of 2.2/2.7 nM; it targets SGLT1 in the GI tract.</p>
    Fórmula:C32H47N3O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:601.80
  • AH22921

    CAS:
    <p>AH22921 is an EP4 prostaglandin receptor antagonist with the ability to antagonize the activation of adenylyl cyclase by prostaglandins in CHO cells. It induces a rightward shift in the PGE? concentration-response curve in these cells, functioning as a non-competitive antagonist. AH22921 is selective for the EP4 receptor, inhibiting its activity in CHO cells without affecting the PGE? concentration-response curve in NPE cells that contain the EP2 receptor.</p>
    Fórmula:C29H35NO5
    Cor e Forma:Solid
    Peso molecular:477.59
  • H3R antagonist 1

    CAS:
    <p>H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).</p>
    Fórmula:C19H23N3O3
    Cor e Forma:Solid
    Peso molecular:341.4
  • TAAR1 agonist 3

    CAS:
    <p>TAAR1 agonist 3 is a potent agonist of Trace Amine-Associated Receptor 1 (TAAR1) with a pEC50 value of 7.6. Additionally, it acts as a full agonist at the α2AR with a pEC50 of 6. TAAR1 agonist 3 is utilized in the research of neuropsychiatric disorders.</p>
    Fórmula:C10H13NO
    Cor e Forma:Solid
    Peso molecular:163.22
  • NK-1 Antagonist 1

    CAS:
    <p>NK-1 Antagonist 1 is a NK-1 receptor antagonist.</p>
    Fórmula:C25H23F6N5O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:539.47
  • CB1/2 agonist 1


    <p>Potent CB1/2 agonist 1; crosses blood-brain barrier; anti-inflammatory, analgesic; for multiple sclerosis research.</p>
    Fórmula:C21H24BrFN2O2
    Cor e Forma:Solid
    Peso molecular:435.33
  • Aclidinium

    CAS:
    <p>Aclidinium, a dual-action compound, serves as a long-acting muscarinic antagonist and a β2-adrenoceptor (β2-AR) agonist, exhibiting bronchodilator properties. It effectively reduces lung hyperinflation, enhances lung function, and prolongs exercise endurance time. This compound is commonly utilized in studies focusing on chronic obstructive pulmonary disease (COPD).</p>
    Fórmula:C26H30NO4S2
    Cor e Forma:Solid
    Peso molecular:484.65
  • YGZ-331

    CAS:
    <p>YGZ-331, a sedative hypnotic, acts by elevating GABA levels as a derivative of the adenosine nucleoside NGBA. It functions through activating A1R and A2aR, and inhibiting the phosphorylation of CaMKII (pCaMKII), thereby exerting its calming effects. Additionally, YGZ-331 reduces spontaneous motor activity in mice.</p>
    Fórmula:C19H23N5O4
    Cor e Forma:Solid
    Peso molecular:385.42
  • VA012

    CAS:
    <p>VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. It has been shown to reduce food intake and prevent weight gain during subchronic administration without causing central nervous system-related discomfort. VA012 is applicable in obesity research.</p>
    Fórmula:C21H19N3
    Cor e Forma:Solid
    Peso molecular:313.40
  • (S)-Bucindolol

    CAS:
    (S)-Bucindolol is an enantiomer of bucindolol, specifically a β1-adrenergic receptor antagonist. It is primarily utilized in research related to heart failure.
    Fórmula:C22H25N3O2
    Cor e Forma:Solid
    Peso molecular:363.45
  • RF9 hydrochloride


    <p>RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).</p>
    Fórmula:C26H39ClN6O3
    Cor e Forma:Solid
    Peso molecular:519.08
  • DA-302168S

    CAS:
    <p>DA-302168S is an orally active, selective GLP-1R agonist with an EC50 value of 1.32 nM. It promotes insulin secretion and has a hypoglycemic effect. Additionally, DA-302168S reduces food intake. It primarily activates GLP-1R in humans and monkeys, with minimal effect on GLP-1R in rats, mice, and dogs. DA-302168S can be used for research in type 2 diabetes and obesity.</p>
    Fórmula:C33H24ClF2N3O5
    Cor e Forma:Solid
    Peso molecular:616.011
  • LJ-4517


    <p>LJ-4517 is an effective A2AAR antagonist (Ki=18.3 nM). LJ-4517 can effectively replace the binding of [3H] ZM241385 at WT A2AAR.</p>
    Fórmula:C19H21N5O3S
    Cor e Forma:Solid
    Peso molecular:399.47
  • TAAR1 agonist 2

    CAS:
    <p>TAAR1 agonist 2 (compound 30), a full agonist at trace amine-associated receptor 1 (TAAR1) (pEC50=7.5), also displays agonistic properties at H1 receptors and activates various muscarinic acetylcholine receptors, including the M2 receptor (pEC50=5). This compound is utilized in researching neuropsychiatric diseases.</p>
    Fórmula:C9H11NO
    Cor e Forma:Solid
    Peso molecular:149.19
  • 5-HT2A/5-HT2C inverse agonist 1

    CAS:
    <p>5-HT2A/5-HT2C inverse agonist 1 serves as a dual and potent inverse agonist for the 5-HT2A and 5-HT2C receptors, with hERG inhibition properties that mitigate cardiovascular risks. Demonstrating significant antipsychotic efficacy in the MK-801-induced mouse model, this compound holds potential for psychosis research.</p>
    Fórmula:C24H35N5O2
    Cor e Forma:Solid
    Peso molecular:425.57
  • GLP-1 receptor agonist 16

    CAS:
    <p>GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.</p>
    Fórmula:C33H31ClFN3O4
    Cor e Forma:Solid
    Peso molecular:588.068
  • SB 243213 dihydrochloride

    CAS:
    <p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>
    Fórmula:C22H21Cl2F3N4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:501.33
  • 8-iso Prostaglandin F3α

    CAS:
    <p>8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA.</p>
    Fórmula:C20H32O5
    Cor e Forma:Solid
    Peso molecular:352.47
  • NK1 receptor antagonist 2

    CAS:
    <p>NK1 Receptor Antagonist 2, a compound targeting the NK1 receptor, holds potential for tinnitus and hearing loss research.</p>
    Fórmula:C31H35F7N4O2
    Cor e Forma:Solid
    Peso molecular:628.62
  • BI-685509

    CAS:
    <p>BI-685509: potent, oral sGC activator, boosts cGMP, enhances NO pathways, for CKD/DKD research.</p>
    Fórmula:C34H38N4O5
    Cor e Forma:Solid
    Peso molecular:582.69
  • MRT-92

    CAS:
    <p>MRT-92 is an antagonist of Smoothened (Smo) with anti-cancer activity, featuring a binding affinity (Ki) of 0.7 nM. It inhibits the Hedgehog signaling pathway by obstructing the overlapping binding sites within the transmembrane domain of the Smoothened receptor and suppresses the proliferation of cerebellar granule cells in rodents (IC50=0.4 nM). MRT-92 is utilized for research into cerebellar gliomas.</p>
    Fórmula:C33H34N4O5
    Cor e Forma:Solid
    Peso molecular:566.65
  • S1PR1 agonist 2

    CAS:
    <p>S1PR1 agonist 2 is potent for autoimmune research (from WO2021175225A1).</p>
    Fórmula:C25H25N5O4
    Cor e Forma:Solid
    Peso molecular:459.50
  • PAR-2-IN-2

    CAS:
    <p>PAR-2-IN-2 (compound P-596) is an inhibitor of protease-activated receptor 2 (PAR-2), with an IC50 of 10.79 μM for SLIGKV and an IC50 greater than 200 μM for trypsin.</p>
    Fórmula:C25H20F3N5O2
    Cor e Forma:Solid
    Peso molecular:479.454
  • Mafoprazine

    CAS:
    <p>Mafoprazine, a phenylpiperazine derivative, exhibits varying affinities for neuronal receptors, primarily exerting its antipsychotic effects through blocking D2 receptors and enhancing α-adrenergic activity. It also increases the activity of dopamine metabolites.</p>
    Fórmula:C22H28FN3O3
    Cor e Forma:Solid
    Peso molecular:401.47
  • ATX inhibitor 27

    CAS:
    <p>ATX inhibitor 27 (Compound 31) is an ATX inhibitor. It demonstrates IC50 values of 13 nM against human autotaxin (hATX) and 23 nM against lysophosphatidylcholine (LPC). By inhibiting the ATX enzyme, ATX inhibitor 27 reduces LPA levels in the body. This compound is applicable in research related to ATX-LPA-associated conditions such as inflammation, neurodegenerative disorders, and cancer.</p>
    Fórmula:C26H26ClN5O3
    Cor e Forma:Solid
    Peso molecular:491.97
  • Teoprolol

    CAS:
    <p>Teoprolol is a blocker of β-adrenergic receptor.</p>
    Fórmula:C23H30N6O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:454.52
  • YM158 free base

    CAS:
    <p>YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87).</p>
    Fórmula:C32H33ClN6O5S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:681.22
  • Atumelnant

    CAS:
    <p>Atumelnant (CRN04894) is an MC2R antagonist used in the study of congenital adrenocortical hyperplasia (CAH) and Cushing's disease (CD).</p>
    Fórmula:C33H42F3N5O3
    Pureza:98.41%
    Cor e Forma:Solid
    Peso molecular:613.71
  • Rocavorexant

    CAS:
    <p>Rocavorexant is an antagonist of the orexin-1 receptor (orexin-1 receptor), exhibiting a pIC50 value of 9.1 for human OX1 and a pIC50 of 6.0 for human OX2.</p>
    Fórmula:C18H19F3N8O
    Cor e Forma:Solid
    Peso molecular:420.392
  • Nolpitantium besilate

    CAS:
    <p>Nolpitantium besilate is a neurokinin-1 receptor antagonist.</p>
    Fórmula:C43H50Cl2N2O5S
    Cor e Forma:Solid
    Peso molecular:777.84
  • Udifitimod

    CAS:
    <p>Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.</p>
    Fórmula:C25H33NO2
    Cor e Forma:Solid
    Peso molecular:379.54
  • Vofopitant

    CAS:
    <p>Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).</p>
    Fórmula:C21H23F3N6O
    Pureza:97.86%
    Cor e Forma:Solid
    Peso molecular:432.44
  • AZD-5672

    CAS:
    <p>AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.</p>
    Fórmula:C32H38F2N2O5S2
    Pureza:98.1%
    Cor e Forma:Solid
    Peso molecular:632.78
  • LSN3318839

    CAS:
    <p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>
    Fórmula:C26H23Cl2N3O2
    Pureza:99.21%
    Cor e Forma:Solid
    Peso molecular:480.39
  • Vofopitant dihydrochloride

    CAS:
    <p>Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.</p>
    Fórmula:C21H25Cl2F3N6O
    Pureza:98.99%
    Cor e Forma:Solid
    Peso molecular:505.36
  • Dersimelagon

    CAS:
    <p>Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.</p>
    Fórmula:C36H45F4N3O5
    Pureza:97.35% - 98.23%
    Cor e Forma:Solid
    Peso molecular:675.75
  • BMS-986141

    CAS:
    <p>BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614</p>
    Fórmula:C27H23N5O5S2
    Pureza:98.43% - 99.26%
    Cor e Forma:Solid
    Peso molecular:561.63
  • BQ-788

    CAS:
    <p>BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.</p>
    Fórmula:C34H51N5O7
    Pureza:98.81%
    Cor e Forma:Solid
    Peso molecular:641.8
  • SB-423562

    CAS:
    <p>SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.</p>
    Fórmula:C26H32N2O4
    Pureza:99.22%
    Cor e Forma:Solid
    Peso molecular:436.54
  • SB-224289 hydrochloride

    CAS:
    <p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>
    Fórmula:C32H33ClN4O3
    Pureza:97.82% - 98.99%
    Cor e Forma:Solid
    Peso molecular:557.08
  • Treprostinil diethanolamine

    CAS:
    <p>Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,</p>
    Fórmula:C27H45NO7
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:495.65
  • PF-07258669

    CAS:
    <p>PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.</p>
    Fórmula:C25H27FN6O2
    Pureza:99.9%
    Cor e Forma:Solid
    Peso molecular:462.52
  • AZD5462

    CAS:
    <p>AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.</p>
    Fórmula:C30H41FN2O6
    Pureza:98.32% - 99.63%
    Cor e Forma:Solid
    Peso molecular:544.65
  • Rolapitant hydrochloride

    CAS:
    <p>Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki of 0.66 nM.</p>
    Fórmula:C25H27ClF6N2O2
    Pureza:98.35% - 99.79%
    Cor e Forma:Solid
    Peso molecular:536.94
  • Pumosetrag Hydrochloride

    CAS:
    <p>Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.</p>
    Fórmula:C15H18ClN3O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:339.84

    Ref: TM-T16683

    1mg
    Descontinuado
    Produto descontinuado
  • CYM 9484

    CAS:
    <p>CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.</p>
    Fórmula:C27H31N3O3S2
    Cor e Forma:Solid
    Peso molecular:509.68

    Ref: TM-T10921

    1mg
    Descontinuado
    2mg
    Descontinuado
    Produto descontinuado
  • Metipranolol hydrochloride

    CAS:
    <p>Metipranolol hydrochloride is a non-selective β-adrenergic receptor blocking agent.</p>
    Fórmula:C17H28ClNO4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:345.86

    Ref: TM-T16066

    1mg
    Descontinuado
    2mg
    Descontinuado
    Produto descontinuado
  • ML-00253764 hydrochloride

    CAS:
    <p>ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).</p>
    Fórmula:C18H19BrClFN2O
    Cor e Forma:Solid
    Peso molecular:413.71

    Ref: TM-T12072

    1mg
    Descontinuado
    Produto descontinuado
  • 7-Desmethyl-agomelatine

    CAS:
    <p>7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.</p>
    Fórmula:C14H15NO2
    Cor e Forma:Solid
    Peso molecular:229.27

    Ref: TM-T10193

    1mg
    Descontinuado
    Produto descontinuado
  • Protease-Activated Receptor-4

    CAS:
    <p>Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.</p>
    Fórmula:C33H46N8O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:666.77

    Ref: TM-T7380

    1mg
    Descontinuado
    Produto descontinuado
  • (Rac)-Rotigotine hydrochloride

    CAS:
    <p>(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.</p>
    Fórmula:C19H26ClNOS
    Cor e Forma:Solid
    Peso molecular:351.93

    Ref: TM-T12676

    1ml*10 (DMSO)
    Descontinuado
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  • ML-290

    CAS:
    <p>ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.</p>
    Fórmula:C24H21F3N2O5S
    Cor e Forma:Solid
    Peso molecular:506.49

    Ref: TM-T16101

    1mg
    Descontinuado
    Produto descontinuado
  • BIBP3226 TFA

    CAS:
    <p>BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).</p>
    Fórmula:C29H32F3N5O5
    Cor e Forma:Solid
    Peso molecular:587.59

    Ref: TM-T10540

    1mg
    Descontinuado
    Produto descontinuado
  • SB-399885 hydrochloride

    CAS:
    <p>SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.</p>
    Fórmula:C18H22Cl3N3O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:482.81

    Ref: TM-T12843

    1mg
    Descontinuado
    Produto descontinuado
  • Beraprost sodium

    CAS:
    <p>Beraprost sodium is a stable and orally active prodrug of PGI2.</p>
    Fórmula:C24H29NaO5
    Cor e Forma:Solid
    Peso molecular:420.481

    Ref: TM-T13859

    1mg
    Descontinuado
    Produto descontinuado
  • HOKU-81

    CAS:
    <p>HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.</p>
    Fórmula:C12H18ClNO2
    Cor e Forma:Solid
    Peso molecular:243.73

    Ref: TM-T15498

    1mg
    Descontinuado
    Produto descontinuado
  • JMV 2959

    CAS:
    <p>JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).</p>
    Fórmula:C30H32N6O2
    Cor e Forma:Solid
    Peso molecular:508.61

    Ref: TM-T11719L

    1mg
    Descontinuado
    2mg
    Descontinuado
    Produto descontinuado
  • SR 146131

    CAS:
    <p>SR 146131 is a potent and selective agonist of the nonpeptide receptor.</p>
    Fórmula:C32H36ClN3O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:610.16

    Ref: TM-T16935

    1mg
    Descontinuado
    Produto descontinuado
  • Arotinolol

    CAS:
    <p>Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.</p>
    Fórmula:C15H21N3O2S3
    Cor e Forma:White Solid
    Peso molecular:371.54

    Ref: TM-T10371

    1mg
    Descontinuado
    Produto descontinuado
  • SHA 68

    CAS:
    <p>SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR) with IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107.</p>
    Fórmula:C26H24FN3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:445.49

    Ref: TM-T12895

    1mg
    Descontinuado
    Produto descontinuado
  • Vornorexant

    CAS:
    <p>Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.</p>
    Fórmula:C23H22FN7O2
    Cor e Forma:Solid
    Peso molecular:447.474

    Ref: TM-T39004

    Produto descontinuado
  • Sarizotan

    CAS:
    <p>Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.</p>
    Fórmula:C22H21FN2O
    Cor e Forma:Solid
    Peso molecular:348.421

    Ref: TM-T40439

    Produto descontinuado
  • Picumeterol

    CAS:
    <p>Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that can be used to improve lung function and reduce airway hyperreactivity in patients with asthma.</p>
    Fórmula:C21H29Cl2N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:426.38

    Ref: TM-T68129

    Produto descontinuado
  • TAK-683

    CAS:
    <p>TAK-683: a full KISS1R agonist, IC50=170 pM; a nonapeptide metastin analog with human EC50=0.96 nM, rat EC50=1.6 nM.</p>
    Fórmula:C64H83N17O13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1298.45

    Ref: TM-TP2156L

    100mg
    Descontinuado
    500mg
    Descontinuado
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  • Amelubant

    CAS:
    <p>Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.</p>
    Fórmula:C33H34N2O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:538.63

    Ref: TM-T14210

    100mg
    Descontinuado
    500mg
    Descontinuado
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  • 1-Oleoyl Lysophosphatidic Acid

    CAS:
    <p>1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.</p>
    Fórmula:C21H41O7P
    Cor e Forma:Solid
    Peso molecular:436.52

    Ref: TM-T36907

    22.91mM*1
    Descontinuado
    22.91mM*100
    Descontinuado
    22.91mM*2.5
    Descontinuado
    22.91mM*500
    Descontinuado
    Produto descontinuado
  • TAK-448

    CAS:
    <p>TAK-448 (MVT-602), a potent KISS1R agonist, IC50: 460 pM, EC50: 632 pM, trialed for Prostate Cancer and Hypogonadism.</p>
    Fórmula:C58H80N16O14
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1225.36

    Ref: TM-TP1094

    1mg
    Descontinuado
    5mg
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  • Propiram fumarate HCl

    CAS:
    <p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>
    Fórmula:C16H25N3O·xClH
    Pureza:99.25%
    Cor e Forma:Soild

    Ref: TM-T28453L

    1mg
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  • CRTh2 antagonist 3

    CAS:
    <p>CRTh2 antagonist 3, a potent molecule, activates PDK1 (EC50=2μM, Kd=8.4μM) and may cause cardiovascular inflammation.</p>
    Fórmula:C19H20N2O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:356.44

    Ref: TM-T10890

    100mg
    Descontinuado
    500mg
    Descontinuado
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  • (R)-(-)-α-Methylhistamine dihydrochloride

    CAS:
    <p>R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.</p>
    Fórmula:C6H13Cl2N3
    Cor e Forma:Solid
    Peso molecular:198.09

    Ref: TM-T24698

    Produto descontinuado
  • dapitant

    CAS:
    <p>Dapitant, a non-peptide, selective antagonist of human NKI receptors, is representative of the 7,7,4-triarylperhydroisoindol-4-ols.</p>
    Fórmula:C37H39NO4
    Cor e Forma:Solid
    Peso molecular:561.71

    Ref: TM-T68049

    Produto descontinuado
  • BX471 hydrochloride

    CAS:
    <p>BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.</p>
    Fórmula:C21H25Cl2FN4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:471.35

    Ref: TM-T14845

    Produto descontinuado
  • Desmethyl cariprazine

    CAS:
    <p>Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).</p>
    Fórmula:C20H30Cl2N4O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:413.38

    Ref: TM-T15100

    100mg
    Descontinuado
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  • 4-Hydroxypropranolol hydrochloride

    CAS:
    <p>4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).</p>
    Fórmula:C16H22ClNO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:311.8

    Ref: TM-T10150

    100mg
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  • 4-Hydroxyatomoxetine

    CAS:
    <p>4-Hydroxyatomoxetine, an active metabolite of Atomoxetine, is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.</p>
    Fórmula:C17H21NO2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:271.35

    Ref: TM-T10145

    100mg
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  • 3-Hydroxybenzylamine

    CAS:
    <p>3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.</p>
    Fórmula:C7H9NO
    Cor e Forma:Solid
    Peso molecular:123.155

    Ref: TM-T124305

    Produto descontinuado
  • Patecibart

    CAS:
    <p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>
    Pureza:98%
    Cor e Forma:Liquid

    Ref: TM-T81538

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  • BRL 15572

    CAS:
    <p>BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.</p>
    Fórmula:C25H27ClN2O
    Cor e Forma:Solid
    Peso molecular:406.95

    Ref: TM-T64501

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  • (Rac)-Zevaquenabant

    CAS:
    <p>(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.</p>
    Fórmula:C25H21ClF3N5O2S
    Cor e Forma:Solid
    Peso molecular:547.98

    Ref: TM-T39074

    Produto descontinuado
  • Canagliflozin-d4

    CAS:
    <p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>
    Fórmula:C24H25FO5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:448.54

    Ref: TM-T10669

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  • 2-Methyl-5-HT hydrochloride

    CAS:
    <p>2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>
    Fórmula:C11H15ClN2O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:226.7

    Ref: TM-T10075L2

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  • Pamoic acid

    CAS:
    <p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>
    Fórmula:C23H16O6
    Pureza:99.99%
    Cor e Forma:Fine Yellow Powder
    Peso molecular:388.37

    Ref: TM-T8353

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  • AM-2232

    CAS:
    <p>AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.</p>
    Fórmula:C24H20N2O
    Pureza:99.37%
    Cor e Forma:Solid
    Peso molecular:352.43

    Ref: TM-T21450

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  • Neurokinin antagonist 1

    CAS:
    <p>Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.</p>
    Fórmula:C38H40N4O3
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:600.75

    Ref: TM-T10056

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  • MEN11467

    CAS:
    <p>MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.</p>
    Fórmula:C38H40N4O3
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:600.75

    Ref: TM-T12000

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  • Flumexadol

    CAS:
    <p>Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.</p>
    Fórmula:C11H12F3NO
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:231.21

    Ref: TM-T11302

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  • 2-Arachidonoylglycerol

    CAS:
    <p>In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand</p>
    Fórmula:C23H38O4
    Pureza:95%
    Cor e Forma:Liquid
    Peso molecular:378.55

    Ref: TM-T14011

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  • GR 218,231

    CAS:
    <p>GR 218,231 is a selective antagonist of D3 dopamine receptor.</p>
    Fórmula:C24H33NO3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:415.59

    Ref: TM-T27431

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  • Imetit dihydrobromide

    CAS:
    <p>Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).</p>
    Fórmula:C6H12Br2N4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:332.06

    Ref: TM-T15565

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  • S1P1 agonist 6

    CAS:
    <p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>
    Fórmula:C25H26F3NO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:445.47

    Ref: TM-T79816

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  • AEF0117

    CAS:
    <p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>
    Fórmula:C29H40O3
    Pureza:99.58%
    Cor e Forma:Solid
    Peso molecular:436.63

    Ref: TM-T79909

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  • 2-MNG

    CAS:
    <p>2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.</p>
    Fórmula:C8H8N2O3S
    Cor e Forma:Liquid
    Peso molecular:212.23

    Ref: TM-T89029

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  • Dimethandrolone Undecanoate

    CAS:
    <p>Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.</p>
    Fórmula:C31H50O3
    Pureza:99.65% - >99.99%
    Cor e Forma:Solid
    Peso molecular:470.73

    Ref: TM-T27176

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