GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.949 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5378 produtos de "GPCR/Proteína-G"
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SJPYT-310
CAS:<p>SJPYT-310 is a selective PXR antagonist, exhibiting no noticeable cytotoxicity.</p>Fórmula:C27H36N4O3Cor e Forma:SolidPeso molecular:464.6Acyline
CAS:<p>Acyline, a GnRH antagonist, suppresses gonadotropins and testosterone in animals and maintains the effect for 2 weeks in men with one dose.</p>Fórmula:C80H102ClN15O14Cor e Forma:SolidPeso molecular:1533.21GLP-1 receptor agonist 11
CAS:<p>GLP-1 Receptor Agonist 11 (compound 3) acts as an effective agonist for the GLP Receptor, finding use in research related to conditions like diabetes and non-alc. fatty liver disease [1].</p>Fórmula:C31H31ClFN3O4Cor e Forma:SolidPeso molecular:564.05CS-0777
CAS:<p>CS-0777 is a potent, selective, and orally active S1P1 agonist (sphingosine 1-phosphate receptor modulator).</p>Fórmula:C21H31N2O5PCor e Forma:SolidPeso molecular:422.45PSB 36
CAS:<p>A1 adenosine receptor antagonist</p>Fórmula:C21H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:386.495-HT6R/MAO-B modulator 1
<p>5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.</p>Fórmula:C33H38N4O3SCor e Forma:SolidPeso molecular:570.74SphK2-IN-1
CAS:<p>SphK2-IN-1 is an SphK2 inhibitor with an IC50 value of 0.359 μM. SphK2-IN-1 can be used to study cancer, inflammation, neurological and cardiovascular diseases.</p>Fórmula:C23H22ClF3N8OCor e Forma:SolidPeso molecular:518.92LY3154207
CAS:<p>LY3154207: selective, potent oral human dopamine D1 receptor PAM, low agonist activity, EC50=3 nM.</p>Fórmula:C24H29Cl2NO3Cor e Forma:SolidPeso molecular:450.425B-NBOH hydrochloride
CAS:<p>25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.</p>Fórmula:C17H21BrClNO3Cor e Forma:SolidPeso molecular:402.711D3/5-HT receptor modulator-1
CAS:<p>D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.</p>Fórmula:C24H29N3O2Cor e Forma:SolidPeso molecular:391.506Tofogliflozin
CAS:Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).Fórmula:C22H26O6Pureza:98%Cor e Forma:SolidPeso molecular:386.44Zaladenant
CAS:<p>Zaladenant is an adenosine receptor antagonist with antitumor properties.</p>Fórmula:C19H15F3N6OCor e Forma:SolidPeso molecular:400.357Fasitibant
CAS:<p>Fasitibant is a potent and selective nonpeptide kinin B2 receptor antagonist.</p>Fórmula:C36H49Cl2N6O6SCor e Forma:SolidPeso molecular:764.78M1069
<p>M1069 is an oral A2A/A2B receptor antagonist, 100x more selective over A1/A3, with antitumor properties by blocking adenosine's immunosuppressive effects.</p>Fórmula:C25H30N4O8SCor e Forma:SolidPeso molecular:546.59BI-113823
CAS:<p>BI-113823 is an orally active and selective bradykinin B1 receptor antagonist. It alleviates mechanical hyperalgesia induced by complete Freund's adjuvant in rats. BI-113823 is applicable for research on chronic inflammatory pain.</p>Fórmula:C26H44N4O5SCor e Forma:SolidPeso molecular:524.716Gemilukast
CAS:<p>Gemilukast (ONO-6950) is a cysteinyl leukotriene 1 and 2 receptor inhibitor that inhibits bronchoconstriction and is used in the treatment of asthma.</p>Fórmula:C36H37F2NO5Pureza:98.27% - 99.5%Cor e Forma:SolidPeso molecular:601.68Merigolix
CAS:<p>Merigolix is a potent gonadotrophin releasing hormone (GnRH) antagonist .</p>Fórmula:C36H35F7N4O6Cor e Forma:SolidPeso molecular:752.68EP4 receptor antagonist 7
CAS:<p>EP4 receptor antagonist 7 (Compound 14) is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP4, with an IC50 of 1.1 nM. This compound inhibits PGE2-induced β-arrestin recruitment in HEK293 cells with an IC50 of 0.9 nM. In RAW 264.7 macrophages, it reduces the expression of PGE2-induced IL-4, macrophage mannose receptor 1 (Mrc1), chitinase-like protein 3 (Chil3), chemokine (C-X-C motif) ligand 1 (Cxcl1), triggering receptor expressed on myeloid cells 2 (Trem2), and arginase 1 (Arg1) mRNA. In the CT26 mouse colon cancer model, EP4 receptor antagonist 7, combined with an anti-PD-1 antibody, inhibits tumor growth and enhances CD8+ T cell infiltration into the tumor.</p>Fórmula:C24H18F3N3O3Cor e Forma:SolidPeso molecular:453.413Tebideutorexant
CAS:<p>Tebideutorexant, an orexin-1 receptor antagonist, shows anti-panic effects in rodents and humans, providing a tool for stress response and psychiatric research.</p>Fórmula:C23H16D2F4N4O2Pureza:98.89%Cor e Forma:SolidPeso molecular:460.42Mrgx2 antagonist-3
CAS:<p>Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of the MrgX2 receptor, with an IC50 range of 0.042-2.5 nM. It blocks downstream G protein signaling and β-arrestin recruitment, inhibiting Mrgx2 receptor-mediated calcium influx and cell degranulation. Mrgx2 antagonist-3 shows potential for research in inflammation-associated diseases and pruritus, such as chronic urticaria and allergic asthma.</p>Fórmula:C15H15F2N3OCor e Forma:SolidPeso molecular:291.30GRK6-IN-5
CAS:<p>GRK6-IN-5 is an inhibitor of the GRK6 polypeptide, with an IC50 of 4.48 μM. GRK6-IN-5 is utilized in research focused on hematological malignancies, inflammatory diseases, and autoimmune disorders.</p>Fórmula:C23H21N3O2Cor e Forma:SolidPeso molecular:371.432MRGPRX2 modulator-1
CAS:<p>MRGPRX2 modulator-1 (example 17), a modulator of the mas-related G-protein receptor X2 (MRGPRX2), is employed in studies focused on inflammation, pain, and autoimmune disorders [1].</p>Fórmula:C20H19F6N5OCor e Forma:SolidPeso molecular:459.395-IAI hydrochloride
CAS:<p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>Fórmula:C9H11ClINCor e Forma:SolidPeso molecular:295.548H1R ligand-1
CAS:<p>H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.</p>Fórmula:C19H23NOCor e Forma:SolidPeso molecular:281.392PD 135158
CAS:PD 135158 is a CCK2 receptor antagonist.Fórmula:C42H61N5O11Pureza:98%Cor e Forma:SolidPeso molecular:811.96Ro4368554
CAS:<p>Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.</p>Fórmula:C19H21N3O2SCor e Forma:SolidPeso molecular:355.454Anthrotainin
CAS:Anthrotainin is a tetracyclic compound that acts as an inhibitor of the binding of P substance (substance P), with an IC50 of 3 μM.Fórmula:C20H17NO9Cor e Forma:SolidPeso molecular:415.35Dopamine D3 receptor ligand-1
<p>Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:</p>Fórmula:C27H29N5OCor e Forma:SolidPeso molecular:439.55MDA7
CAS:<p>MDA7 is a selective agonist of the cannabinoid receptor 2 (CB2), demonstrating an EC50 of 128 nM in human CB2 receptors and 67.4 nM in rat CB2 receptors. The compound exhibits good affinity for CB2 receptors, with Ki values of 422 nM for humans and 238 nM for rats. In rat models, MDA7 shows analgesic activity.</p>Fórmula:C22H25NO2Cor e Forma:SolidPeso molecular:335.439BIBO3304 diTFA
CAS:<p>BIBO3304 (diTFA), a selective neuropeptide Y (NPY) Y1 receptor antagonist, demonstrates oral efficacy. It exhibits high affinity for Y1 receptors in both humans and rats, with IC50 values of 0.38 nM and 0.72 nM, respectively. Additionally, BIBO3304 (diTFA) enhances bone-tendon healing via the Wnt/β-catenin signaling pathway [1] [2] [3].</p>Fórmula:C33H37F6N7O7Cor e Forma:SolidPeso molecular:757.68H3R antagonist 5
CAS:<p>H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.</p>Fórmula:C23H32N2O4Cor e Forma:SolidPeso molecular:400.511Burapitant
CAS:<p>Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.</p>Fórmula:C31H35Cl2F6N3O3Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:682.52CI-988
CAS:<p>CCK2 (CCK-B) receptor antagonist</p>Fórmula:C35H42N4O6Pureza:98%Cor e Forma:SolidPeso molecular:614.73MRGPRX1 agonist 3
<p>Compound 1f, a potent MRGPRX1 agonist, has an EC50 of 0.22 μM, useful for neuropathic pain studies.</p>Fórmula:C14H11FN2OSCor e Forma:SolidPeso molecular:274.31R-96544 hydrochloride
CAS:<p>5-HT2 receptor antagonist</p>Fórmula:C22H29NO3Pureza:98%Cor e Forma:SolidPeso molecular:355.47Iralukast (CGP 45715A)
CAS:<p>Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.</p>Fórmula:C38H37F3O8SCor e Forma:SolidPeso molecular:710.76CVT-5440
CAS:<p>CVT-5440 is a selective, high-affinity (2B) adenosine receptor antagonist with good selectivity.</p>Fórmula:C27H28N6O5Cor e Forma:SolidPeso molecular:516.55(Rac)-BI 703704
CAS:<p>(Rac)-BI 703704 is a potent activator of soluble guanylyl cyclase (sGC).</p>Fórmula:C32H37N3O4SPureza:98%Cor e Forma:SolidPeso molecular:559.72(S)-Butaprost free acid
CAS:<p>(S)-Butaprost (free acid) is a potent and highly selective EP2 receptor agonist[1].</p>Fórmula:C23H38O5Cor e Forma:SolidPeso molecular:394.54AM8936
<p>AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.</p>Fórmula:C25H33NO3Cor e Forma:SolidPeso molecular:395.53CCR1 antagonist 11 hydrochloride
<p>Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.</p>Cor e Forma:SolidAlixorexton
CAS:<p>Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.</p>Fórmula:C21H30N2O5SCor e Forma:SolidPeso molecular:422.538A1AR antagonist 1
<p>Compound 18g, a potent A1AR blocker with Ki: 2.08 nM (hA1), 6.91 nM (hA2A), 31.2 nM (hA2B).</p>Fórmula:C18H14N4OCor e Forma:SolidPeso molecular:302.33Revexepride
CAS:<p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>Fórmula:C21H32ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:425.95Org-6906
CAS:<p>DCB-3503, a tylophorine analog, may treat cancer and suppress immunity by blocking protein synthesis and modulating HSC70's ATPase activity.</p>Fórmula:C13H16ClNPureza:98%Cor e Forma:SolidPeso molecular:221.73CP-608039
CAS:<p>CP-608039 is a selective adenosine A3 receptor agonist for both human A3 and human A1 receptors.</p>Fórmula:C23H25ClN8O5Cor e Forma:SolidPeso molecular:528.95Terguride
CAS:<p>Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.</p>Fórmula:C20H28N4OCor e Forma:SolidPeso molecular:340.46Sulprostone
CAS:<p>EP3 and EP1 receptor agonist</p>Fórmula:C23H31NO7SPureza:98%Cor e Forma:White To Off-White SolidPeso molecular:465.56GPBAR1-IN-3
CAS:<p>GPBAR1-IN-3 (Compound 14) is both a selective agonist for GPBAR1, with an EC50 value of 0.17 μM, and an antagonist for CysLT1R [1].</p>Fórmula:C21H23NO2Cor e Forma:SolidPeso molecular:321.41CP-865569
CAS:<p>CP-865569 is a CCR1 antagonist useful in the research of inflammatory and autoimmune diseases, including conditions such as rheumatoid arthritis and multiple sclerosis.</p>Fórmula:C22H26ClFN2O5SCor e Forma:SolidPeso molecular:484.9692,3-dinor-11β-Prostaglandin F2α
CAS:<p>2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where</p>Fórmula:C18H30O5Cor e Forma:SolidPeso molecular:326.43SCH-900822
CAS:<p>SCH-900822 is a potent and selective glucagon receptor antagonist.</p>Fórmula:C34H43Cl2N7O2Cor e Forma:SolidPeso molecular:652.66MRS2179 tetrasodium hydrate
<p>MRS2179 blocks turkey P2Y1 receptor (Kb 102 nM, pA2 6.99), affects platelet aggregation, and has varying IC50s on P2 receptors.</p>Fórmula:C11H15N5Na4O10P2Cor e Forma:SolidPeso molecular:576.21(E/Z)-Ozagrel sodium
CAS:<p>(E/Z)-Ozagrel (sodium) [(E/Z)-OKY-046 (sodium)] is a mixture of the EZ isomers of Ozagrel (sodium). It acts as a thromboxane A2 (TXA2) synthase inhibitor. As an antiplatelet agent, Ozagrel (sodium) selectively inhibits human platelet aggregation, with an IC50 of 53.12 μM.</p>Fórmula:C13H11N2NaO2Cor e Forma:SolidPeso molecular:250.228RF9 hydrochloride
<p>RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).</p>Fórmula:C26H39ClN6O3Cor e Forma:SolidPeso molecular:519.08Rivenprost
CAS:<p>Rivenprost, selective EP4 agonist (Ki: 0.7 nM), promotes bone growth, osteoblast differentiation, and aids wound healing.</p>Fórmula:C24H34O6SCor e Forma:SolidPeso molecular:450.59LPA2 antagonist 5
CAS:<p>LPA2 antagonist 5 (EX1) functions as an antagonist of LPA2, with an IC50 value of 4.05 nM.</p>Fórmula:C17H17F3N2O5Cor e Forma:SolidPeso molecular:386.323GHSR-1a agonist-1
CAS:<p>GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a) with an EC50 of 0.49 nM. It effectively stimulates the release of endogenous growth hormone by activating GHSR-1a. Doses as low as 0.1 mg/kg (administered orally) can increase body weight and length in 4-week-old rats. GHSR-1a agonist-1 is applicable in research on pediatric growth and developmental delays.</p>Fórmula:C30H37N5O4Cor e Forma:SolidPeso molecular:531.646MF-592
CAS:<p>MF-592: EP4 receptor antagonist, hEP4 IC50 3 nM, hWB IC50 78 nM, great oral PK, rat arthritis ED50 0.1 mg/kg/day, promising for development.</p>Fórmula:C34H33Cl2N3O6SCor e Forma:SolidPeso molecular:682.61H3R antagonist 2
<p>Compound 23: H3R antagonist with 170 nM Ki; inhibits AChE, BChE, hMAO B; IC50s: 180, 880, 775 nM; anti-pain, memory boost; crosses BBB. [1]</p>Fórmula:C24H29NO3Cor e Forma:SolidPeso molecular:379.49LY 215840
CAS:<p>5-HT2/5-HT7 receptor antagonist</p>Fórmula:C24H33N3O2Pureza:98%Cor e Forma:SolidPeso molecular:395.54Thielavin B
CAS:<p>Thielavin B, from Thielavia terricola, inhibits prostaglandin E2 synthesis and reduces rat oedema.</p>Fórmula:C31H34O10Cor e Forma:SolidPeso molecular:566.6CCR7 Ligand 1
CAS:<p>CCR7-Cmp2105 is a thiadiazole-dioxide allosteric antagonist for CCR7 with a Kd of 3 nM and IC50 of 7.3 μM against arrestin binding.</p>Fórmula:C22H29N5O5SCor e Forma:SolidPeso molecular:475.56CB2 receptor antagonist 1
CAS:<p>Compound 29 is a potent, CB2-selective antagonist/reverse agonist. Derivatives 23 & 24 offer antinociception; 24 activates cannabinoid/TRPV1 receptors.</p>Fórmula:C28H47NO3Cor e Forma:SolidPeso molecular:445.68BW A868C
CAS:BW A868C is a potent, selective PGD2 antagonist and a BW245C analogue, inert to other prostaglandin receptors.Fórmula:C25H37N3O5Cor e Forma:SolidPeso molecular:459.58GLP-1 receptor agonist 16
CAS:<p>GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.</p>Fórmula:C33H31ClFN3O4Cor e Forma:SolidPeso molecular:588.0688-iso Prostaglandin F3α
CAS:<p>8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA.</p>Fórmula:C20H32O5Cor e Forma:SolidPeso molecular:352.47NK1 receptor antagonist 2
CAS:<p>NK1 Receptor Antagonist 2, a compound targeting the NK1 receptor, holds potential for tinnitus and hearing loss research.</p>Fórmula:C31H35F7N4O2Cor e Forma:SolidPeso molecular:628.62CCR4 antagonist 2
CAS:<p>CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg</p>Fórmula:C26H28Cl2N6OPureza:98%Cor e Forma:SolidPeso molecular:511.45LP 12 hydrochloride hydrate
<p>LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.</p>Fórmula:C32H39N3O·HCl·xH2OCor e Forma:SolidBI-685509
CAS:<p>BI-685509: potent, oral sGC activator, boosts cGMP, enhances NO pathways, for CKD/DKD research.</p>Fórmula:C34H38N4O5Cor e Forma:SolidPeso molecular:582.69S1PR1 agonist 2
CAS:<p>S1PR1 agonist 2 is potent for autoimmune research (from WO2021175225A1).</p>Fórmula:C25H25N5O4Cor e Forma:SolidPeso molecular:459.50PAR-2-IN-2
CAS:<p>PAR-2-IN-2 (compound P-596) is an inhibitor of protease-activated receptor 2 (PAR-2), with an IC50 of 10.79 μM for SLIGKV and an IC50 greater than 200 μM for trypsin.</p>Fórmula:C25H20F3N5O2Cor e Forma:SolidPeso molecular:479.454Teoprolol
CAS:<p>Teoprolol is a blocker of β-adrenergic receptor.</p>Fórmula:C23H30N6O4Pureza:98%Cor e Forma:SolidPeso molecular:454.52Henagliflozin
CAS:<p>Henagliflozin (SHR3824): an oral, selective SGLT2 inhibitor, weak on SGLT1.</p>Fórmula:C22H24ClFO7Cor e Forma:SolidPeso molecular:454.87YM158 free base
CAS:<p>YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87).</p>Fórmula:C32H33ClN6O5S2Pureza:98%Cor e Forma:SolidPeso molecular:681.22DSP-1053 benzenesulfonate
CAS:<p>DSP-1053: Benzylpiperidine-based, potent SERT inhibitor (Ki=1.02nM), partial 5-HT1A receptor agonist (Ki=5.05nM), antidepressant.</p>Fórmula:C32H38BrNO7SCor e Forma:SolidPeso molecular:660.62RBM10-8
CAS:<p>RBM10-8 irreversibly inhibits human sphingosine-1- phosphate lyase (hS1PL) while behaving also as an enzyme substrate.</p>Fórmula:C17H36NO5PCor e Forma:SolidPeso molecular:365.45Rocavorexant
CAS:<p>Rocavorexant is an antagonist of the orexin-1 receptor (orexin-1 receptor), exhibiting a pIC50 value of 9.1 for human OX1 and a pIC50 of 6.0 for human OX2.</p>Fórmula:C18H19F3N8OCor e Forma:SolidPeso molecular:420.392Elsovaptan
CAS:<p>Elsovaptan is an antagonist of the vasopressin receptor and is applicable for research in Alzheimer's disease.</p>Fórmula:C19H20ClN5O2Cor e Forma:SolidPeso molecular:385.847Nolpitantium besilate
CAS:<p>Nolpitantium besilate is a neurokinin-1 receptor antagonist.</p>Fórmula:C43H50Cl2N2O5SCor e Forma:SolidPeso molecular:777.84Udifitimod
CAS:<p>Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.</p>Fórmula:C25H33NO2Cor e Forma:SolidPeso molecular:379.54MRS2279
CAS:<p>Selective, high affinity competitive antagonist of the P2Y1 receptor</p>Fórmula:C13H18ClN5O8P2Pureza:98%Cor e Forma:SolidPeso molecular:469.71Inupadenant HCl
CAS:<p>Inupadenant (EOS-850) is a selective A2a receptor antagonist, targeting immunosuppression in tumors.</p>Fórmula:C25H27ClF2N8O4S2Cor e Forma:SolidPeso molecular:641.11UK-432097
CAS:<p>UK 432097 is an adenosine A2A agonist.</p>Fórmula:C40H47N11O6Cor e Forma:SolidPeso molecular:777.87APJ receptor agonist 3
CAS:<p>APJ receptor agonist 3 is a highly effective and orally administerable agonist of the APJ receptor, demonstrating a potent EC50 value of 0.027 nM.</p>Fórmula:C26H29ClN4O5Cor e Forma:SolidPeso molecular:512.98BIIE-0246 HCl
CAS:<p>BIIE-0246: A potent, non-peptide Y2 receptor antagonist; >650-fold more selective than Y1, Y4, Y5.</p>Fórmula:C49H59Cl2N11O6Cor e Forma:SolidPeso molecular:968.97L-365260 hemihydrate
<p>L-365260 hemihydrate: selective oral CCK-B/gastrin blocker, Ki=1.9/2.0 nM, competes with guinea pig receptors.</p>Fórmula:C24H24N4O3Cor e Forma:SolidPeso molecular:407.47NMDAR antagonist 5
CAS:<p>NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET). It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 μM) and effective activity on monoamine transporters (SERT IC50= 1.1 μM, DAT IC50= 0.7 μM, NET IC50= 2.7 μM). NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50> 100 μM; cardiac toxicity IC50= 24.5 μM). It has antidepressant properties and is useful for depression research.</p>Fórmula:C17H21N3Cor e Forma:SolidPeso molecular:267.369SSTR5 antagonist 2 hydrochloride
<p>SSTR5 antagonist 2 hydrochloride: potent, oral SSTR5 blocker with potential in type 2 diabetes research.</p>Fórmula:C32H36ClFN2O5Cor e Forma:SolidPeso molecular:583.09Ici D1542
CAS:Ici D1542: potent TXS inhibitor & TXA2 receptor antagonist, effective thromboxane blocker in vitro.Fórmula:C25H30N2O7Pureza:98%Cor e Forma:SolidPeso molecular:470.51Abarelix acetate
CAS:<p>Abarelix acetate: synthetic GnRHR antagonist, spikes histamine, lowers LH and testosterone temporarily, used in advanced prostate cancer.</p>Fórmula:C72H95ClN14O14·xC2H4O2Cor e Forma:SolidPeso molecular:1476.14K-14585
CAS:<p>K-14585 blocks PAR(2), reduces NFkappaB activity, and IL-8 response, but alone can boost IL-8.</p>Fórmula:C51H56Cl2N8O4Cor e Forma:SolidPeso molecular:915.95WIN 66306
CAS:<p>WIN 66306: Cyclic heptapeptide, blocks NK1/NK2 receptors, inhibits substance P-triggered contractions in guinea pig ileum.</p>Fórmula:C41H52N8O9Cor e Forma:SolidPeso molecular:800.9YNT-3708
CAS:<p>YNT-3708 is an orexin receptor (OXR) agonist, exhibiting EC50 values of 14.6 nM for OX1R and 277 nM for OX2R.</p>Fórmula:C35H36N4O6SCor e Forma:SolidPeso molecular:640.749Protease-Activated Receptor-1 antagonist 3
<p>PAR-1 antagonist 3: potent (IC50: 7 nM), binds hERG K+ channels (IC50: 9 μM).</p>Fórmula:C30H34N4O3Cor e Forma:SolidPeso molecular:498.62Vibegron
CAS:<p>Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).</p>Fórmula:C26H28N4O3Cor e Forma:SolidPeso molecular:444.53AAZ-A 154 benzoate
CAS:<p>AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.</p>Fórmula:C21H26N2O3Cor e Forma:SolidPeso molecular:354.44AAZ-A 154
CAS:<p>AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.</p>Fórmula:C14H20N2OCor e Forma:SolidPeso molecular:232.32AAZ-A 154 mesylate
CAS:<p>AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.</p>Fórmula:C15H24N2O4SCor e Forma:SolidPeso molecular:328.43NCATS-SM4420
CAS:<p>NCATS-SM4420 (Compound A35) is an orally effective ligand for the thyroid-stimulating hormone receptor (TSHR) that inhibits the proliferation of MDA-T32 and MDA-T85 cells both in vitro and in vivo, with IC50 values of 0.71 μM and 0.38 μM, respectively. Additionally, it suppresses the metastasis of MDA-T85F1 in mice. NCATS-SM4420 holds potential for research in the field of thyroid cancer.</p>Fórmula:C31H27N3O5Cor e Forma:SolidPeso molecular:521.56MED 27
CAS:<p>MED 27 is an inhibitor of thromboxane synthase and thromboxane A2 receptors. It effectively inhibits rat platelet aggregation at doses significantly lower than those required for acetylsalicylic acid.</p>Fórmula:C24H25N5O5Cor e Forma:SolidPeso molecular:463.49PF-07054894
CAS:<p>PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.</p>Fórmula:C24H30N6O4Cor e Forma:SolidPeso molecular:466.53Cloprostenol
CAS:<p>Cloprostenol is a synthetic prostaglandin and PGF2α analogue used in animals to terminate pregnancy and induce corpus luteum dissolution.</p>Fórmula:C22H29ClO6Pureza:99.81%Cor e Forma:Clear Colorless To Light Yellowish LiquidPeso molecular:424.92Lisuride
CAS:<p>Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.</p>Fórmula:C20H26N4OCor e Forma:SolidPeso molecular:338.45RTIOXA-43
CAS:<p>RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.</p>Fórmula:C37H37N5O5SPureza:99.17%Cor e Forma:SolidPeso molecular:663.79Sulamserod hydrochloride
CAS:<p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>Fórmula:C19H29Cl2N3O5SCor e Forma:SolidPeso molecular:482.42SEP-363856 mesylate
CAS:<p>SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.</p>Fórmula:C10H17NO4S2Cor e Forma:SolidPeso molecular:279.38BRL-37344
CAS:<p>BRL-37344 is a selective β3-adrenergic receptor agonist. It significantly reduces the body weight of obese mice.</p>Fórmula:C19H22ClNO4Cor e Forma:SolidPeso molecular:363.84BNS808
CAS:<p>BNS808 is an orally active, selective CB1R antagonist with an IC50 of 0.8 nM, demonstrating significant selectivity for CB2R and minimal brain penetration. It is being studied for the treatment of obesity and related metabolic complications, such as metabolic dysfunction-associated steatotic liver disease (MASLD). BNS808 reduces drug exposure to the central nervous system, enhancing safety, and minimizes drug interactions through high plasma protein binding.</p>Fórmula:C25H20Cl3N3O3SCor e Forma:SolidPeso molecular:548.869Zafirlukast metabolite M1
CAS:<p>Zafirlukast metabolite M1 (compound 15) is an inhibitor used in the treatment of asthma and other allergic pulmonary conditions, effectively antagonizing leukotriene activity.</p>Fórmula:C25H25N3O4SCor e Forma:SolidPeso molecular:463.549PF-06372222
CAS:<p>PF-06372222: a small-molecule that modulates GCGR and antagonizes GLP-1R, affecting insulin and glucagon.</p>Fórmula:C26H28F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:515.53SR 140333
CAS:<p>SR 140333 is a NK1 receptor antagonist.</p>Fórmula:C37H45Cl3N2O2Pureza:98%Cor e Forma:SolidPeso molecular:656.12BMS-986141
CAS:<p>BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614</p>Fórmula:C27H23N5O5S2Pureza:98.43% - 99.26%Cor e Forma:SolidPeso molecular:561.63PF-07258669
CAS:<p>PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.</p>Fórmula:C25H27FN6O2Pureza:99.9%Cor e Forma:SolidPeso molecular:462.52LSN3318839
CAS:<p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>Fórmula:C26H23Cl2N3O2Pureza:99.21%Cor e Forma:SolidPeso molecular:480.39SB-423562
CAS:<p>SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.</p>Fórmula:C26H32N2O4Pureza:99.22%Cor e Forma:SolidPeso molecular:436.54Vofopitant
CAS:<p>Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).</p>Fórmula:C21H23F3N6OPureza:97.86%Cor e Forma:SolidPeso molecular:432.44Vofopitant dihydrochloride
CAS:Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.Fórmula:C21H25Cl2F3N6OPureza:98.99%Cor e Forma:SolidPeso molecular:505.36Dersimelagon
CAS:<p>Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.</p>Fórmula:C36H45F4N3O5Pureza:97.35% - 98.23%Cor e Forma:SolidPeso molecular:675.75AZD-5672
CAS:<p>AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.</p>Fórmula:C32H38F2N2O5S2Pureza:98.1%Cor e Forma:SolidPeso molecular:632.78SB-224289 hydrochloride
CAS:<p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>Fórmula:C32H33ClN4O3Pureza:97.82% - 98.99%Cor e Forma:SolidPeso molecular:557.08BQ-788
CAS:<p>BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.</p>Fórmula:C34H51N5O7Pureza:98.81%Cor e Forma:SolidPeso molecular:641.8Treprostinil diethanolamine
CAS:<p>Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,</p>Fórmula:C27H45NO7Pureza:99.86%Cor e Forma:SolidPeso molecular:495.65AZD5462
CAS:<p>AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.</p>Fórmula:C30H41FN2O6Pureza:98.32% - 99.63%Cor e Forma:SolidPeso molecular:544.65Rolapitant hydrochloride
CAS:<p>Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki of 0.66 nM.</p>Fórmula:C25H27ClF6N2O2Pureza:98.35% - 99.79%Cor e Forma:SolidPeso molecular:536.94ML-00253764 hydrochloride
CAS:<p>ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).</p>Fórmula:C18H19BrClFN2OCor e Forma:SolidPeso molecular:413.71HOKU-81
CAS:<p>HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.</p>Fórmula:C12H18ClNO2Cor e Forma:SolidPeso molecular:243.73SHA 68
CAS:<p>SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR) with IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107.</p>Fórmula:C26H24FN3O3Pureza:98%Cor e Forma:SolidPeso molecular:445.49BIBP3226 TFA
CAS:<p>BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).</p>Fórmula:C29H32F3N5O5Cor e Forma:SolidPeso molecular:587.59SB-399885 hydrochloride
CAS:SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.Fórmula:C18H22Cl3N3O4SPureza:98%Cor e Forma:SolidPeso molecular:482.817-Desmethyl-agomelatine
CAS:<p>7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.</p>Fórmula:C14H15NO2Cor e Forma:SolidPeso molecular:229.27Metipranolol hydrochloride
CAS:<p>Metipranolol hydrochloride is a non-selective β-adrenergic receptor blocking agent.</p>Fórmula:C17H28ClNO4Pureza:98%Cor e Forma:SolidPeso molecular:345.86Beraprost sodium
CAS:Beraprost sodium is a stable and orally active prodrug of PGI2.Fórmula:C24H29NaO5Cor e Forma:SolidPeso molecular:420.481SR 146131
CAS:<p>SR 146131 is a potent and selective agonist of the nonpeptide receptor.</p>Fórmula:C32H36ClN3O5SPureza:98%Cor e Forma:SolidPeso molecular:610.16CYM 9484
CAS:CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.Fórmula:C27H31N3O3S2Cor e Forma:SolidPeso molecular:509.68Pumosetrag Hydrochloride
CAS:<p>Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.</p>Fórmula:C15H18ClN3O2SPureza:98%Cor e Forma:SolidPeso molecular:339.84(Rac)-Rotigotine hydrochloride
CAS:<p>(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.</p>Fórmula:C19H26ClNOSCor e Forma:SolidPeso molecular:351.93JMV 2959
CAS:JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).Fórmula:C30H32N6O2Cor e Forma:SolidPeso molecular:508.61Protease-Activated Receptor-4
CAS:<p>Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.</p>Fórmula:C33H46N8O7Pureza:98%Cor e Forma:SolidPeso molecular:666.77Arotinolol
CAS:<p>Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.</p>Fórmula:C15H21N3O2S3Cor e Forma:White SolidPeso molecular:371.54ML-290
CAS:<p>ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.</p>Fórmula:C24H21F3N2O5SCor e Forma:SolidPeso molecular:506.49TAK-448
CAS:<p>TAK-448 (MVT-602), a potent KISS1R agonist, IC50: 460 pM, EC50: 632 pM, trialed for Prostate Cancer and Hypogonadism.</p>Fórmula:C58H80N16O14Pureza:98%Cor e Forma:SolidPeso molecular:1225.36Anti-GLP1R Antibody
<p>Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.</p>Cor e Forma:Odour LiquidGSK-3050002
<p>GSK-3050002 (HGS-1035) is a humanized IgG1 antibody that targets and binds to CCL20. It holds potential for inflammation research. For isotype control, refer to Human IgG1 kappa, Isotype Control.</p>Cor e Forma:Odour Liquid(R)-(-)-α-Methylhistamine dihydrochloride
CAS:<p>R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.</p>Fórmula:C6H13Cl2N3Cor e Forma:SolidPeso molecular:198.09BX471 hydrochloride
CAS:<p>BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.</p>Fórmula:C21H25Cl2FN4O3Pureza:98%Cor e Forma:SolidPeso molecular:471.354-Hydroxypropranolol hydrochloride
CAS:<p>4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).</p>Fórmula:C16H22ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:311.8Goserelin acetate(65807-02-5 Free base)
<p>Goserelin acetate （ICI-118630 acetate） is a naturally occurring decapeptide, a GnRH (gonadotropin releasing hormone) agonist that reduces the production of sex hormones (testosterone and estrogen) for the treatment of prostate cancer, breast cancer and endometriosis.</p>Pureza:99.77%Cor e Forma:Odour SolidDesmethyl cariprazine
CAS:<p>Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).</p>Fórmula:C20H30Cl2N4OPureza:98%Cor e Forma:SolidPeso molecular:413.384-Hydroxyatomoxetine
CAS:<p>4-Hydroxyatomoxetine, an active metabolite of Atomoxetine, is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.</p>Fórmula:C17H21NO2Pureza:98%Cor e Forma:SolidPeso molecular:271.35CRTh2 antagonist 3
CAS:<p>CRTh2 antagonist 3, a potent molecule, activates PDK1 (EC50=2μM, Kd=8.4μM) and may cause cardiovascular inflammation.</p>Fórmula:C19H20N2O3SPureza:98%Cor e Forma:SolidPeso molecular:356.441-Oleoyl Lysophosphatidic Acid
CAS:<p>1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.</p>Fórmula:C21H41O7PCor e Forma:SolidPeso molecular:436.52Ref: TM-T36907
Produto descontinuado3-Hydroxybenzylamine
CAS:<p>3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.</p>Fórmula:C7H9NOCor e Forma:SolidPeso molecular:123.155Sarizotan
CAS:<p>Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.</p>Fórmula:C22H21FN2OCor e Forma:SolidPeso molecular:348.421BRL 15572
CAS:<p>BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.</p>Fórmula:C25H27ClN2OCor e Forma:SolidPeso molecular:406.95Amelubant
CAS:<p>Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.</p>Fórmula:C33H34N2O5Pureza:98%Cor e Forma:SolidPeso molecular:538.63TAK-683
CAS:<p>TAK-683: a full KISS1R agonist, IC50=170 pM; a nonapeptide metastin analog with human EC50=0.96 nM, rat EC50=1.6 nM.</p>Fórmula:C64H83N17O13Pureza:98%Cor e Forma:SolidPeso molecular:1298.45Picumeterol
CAS:<p>Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that can be used to improve lung function and reduce airway hyperreactivity in patients with asthma.</p>Fórmula:C21H29Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:426.38dapitant
CAS:<p>Dapitant, a non-peptide, selective antagonist of human NKI receptors, is representative of the 7,7,4-triarylperhydroisoindol-4-ols.</p>Fórmula:C37H39NO4Cor e Forma:SolidPeso molecular:561.71(Rac)-Zevaquenabant
CAS:<p>(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.</p>Fórmula:C25H21ClF3N5O2SCor e Forma:SolidPeso molecular:547.98Propiram fumarate HCl
CAS:<p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>Fórmula:C16H25N3O·xClHPureza:99.25%Cor e Forma:SoildVornorexant
CAS:<p>Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.</p>Fórmula:C23H22FN7O2Cor e Forma:SolidPeso molecular:447.474Patecibart
CAS:<p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>Pureza:98%Cor e Forma:LiquidCanagliflozin-d4
CAS:<p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>Fórmula:C24H25FO5SPureza:98%Cor e Forma:SolidPeso molecular:448.54Ref: TM-T10669
Produto descontinuado2-Methyl-5-HT hydrochloride
CAS:2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Fórmula:C11H15ClN2OPureza:98%Cor e Forma:SolidPeso molecular:226.7AM-2232
CAS:<p>AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.</p>Fórmula:C24H20N2OPureza:99.37%Cor e Forma:SolidPeso molecular:352.43Pamoic acid
CAS:<p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>Fórmula:C23H16O6Pureza:99.99%Cor e Forma:Fine Yellow PowderPeso molecular:388.37Imetit dihydrobromide
CAS:<p>Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).</p>Fórmula:C6H12Br2N4SPureza:98%Cor e Forma:SolidPeso molecular:332.06Neurokinin antagonist 1
CAS:<p>Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.</p>Fórmula:C38H40N4O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:600.75GR 218,231
CAS:<p>GR 218,231 is a selective antagonist of D3 dopamine receptor.</p>Fórmula:C24H33NO3SPureza:98%Cor e Forma:SolidPeso molecular:415.592-Arachidonoylglycerol
CAS:<p>In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand</p>Fórmula:C23H38O4Pureza:95%Cor e Forma:LiquidPeso molecular:378.55Flumexadol
CAS:<p>Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.</p>Fórmula:C11H12F3NOPureza:98%Cor e Forma:SolidPeso molecular:231.21MEN11467
CAS:MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.Fórmula:C38H40N4O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:600.75AEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Fórmula:C29H40O3Pureza:99.58%Cor e Forma:SolidPeso molecular:436.63S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Fórmula:C25H26F3NO3Pureza:98%Cor e Forma:SolidPeso molecular:445.47Dimethandrolone Undecanoate
CAS:<p>Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.</p>Fórmula:C31H50O3Pureza:99.65% - >99.99%Cor e Forma:SolidPeso molecular:470.73Ref: TM-T27176
Produto descontinuado2-MNG
CAS:<p>2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.</p>Fórmula:C8H8N2O3SCor e Forma:LiquidPeso molecular:212.23
