GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.949 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5378 produtos de "GPCR/Proteína-G"
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UCM 549
CAS:<p>UCM 549 is a bioactive chemical.</p>Fórmula:C19H21NO2Cor e Forma:SolidPeso molecular:295.38BMS-196085
CAS:<p>BMS-196085 is an effective and selective human β( 3) All agonists of adrenergic receptors, in β( 1) Partial agonist activity was 45%.</p>Fórmula:C24H26F2N2O5SCor e Forma:SolidPeso molecular:492.54Asenapine citrate
CAS:<p>Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).</p>Fórmula:C23H24ClNO8Cor e Forma:SolidPeso molecular:477.89Pancreatic Polypeptide, bovine
CAS:Agonist at Y4 neuropeptide Y receptors.Fórmula:C186H287N53O56S2Pureza:98%Cor e Forma:SolidPeso molecular:4225.78Agaridoxin
CAS:<p>Agaridoxin is a mushroom metabolite.</p>Fórmula:C11H14N2O5Cor e Forma:SolidPeso molecular:254.242T-10430
<p>T-10430 is a potent and orally active agonist of the leukotriene B4 receptor 2 (BLT2). It shows potential for use in psoriasis research.</p>Fórmula:C17H22N6OCor e Forma:SolidPeso molecular:326.396Ethylpropyltryptamine
CAS:<p>Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.</p>Fórmula:C15H22N2Cor e Forma:SolidPeso molecular:230.35Dexchlorpheniramine free base
CAS:<p>Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.</p>Fórmula:C16H19ClN2Pureza:98%Cor e Forma:Oily Liquid SolidPeso molecular:274.79Neurokinin B (TFA)
CAS:<p>Neurokinin B TFA, a tachykinin, targets NK1R, NK2R, nk3r GPCRs, modulating effects.</p>Fórmula:C59H81F6N13O18S2Pureza:98%Cor e Forma:SolidPeso molecular:1438.47ECPLA
CAS:<p>ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.</p>Fórmula:C21H25N3OCor e Forma:SolidPeso molecular:335.44FR167344 free base
CAS:<p>FR167344 free base: oral, nonpeptide B2 bradykinin receptor antagonist, high-affinity (IC50: 65 nM), no B1 affinity.</p>Fórmula:C30H28BrCl2N5O4Pureza:98%Cor e Forma:SolidPeso molecular:673.38IRAK inhibitor 4 trans
<p>IRAK inhibitor 4 targets and blocks IRAK4 activity; refers to its trans molecular configuration.</p>Fórmula:C33H35F3N6O3Pureza:98%Cor e Forma:SolidPeso molecular:620.66Urocortin, rat
CAS:<p>Endogenous CRF agonist. Ki values are 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β respectively.</p>Fórmula:C206H338N62O64Pureza:98%Cor e Forma:SolidPeso molecular:4707.2619(R)-hydroxy Prostaglandin E1
CAS:<p>19(R)-hydroxy Prostaglandin E1 is an agonist of EP1 and EP3 receptor subtypes and exhibits contractile activity on smooth muscle and is the major prostaglandin</p>Fórmula:C20H34O6Cor e Forma:SolidPeso molecular:370.486Ki16198
CAS:<p>Ki16198, a methyl ester derivative of Ki16425, blocks LPA1/3, weak on LPA2; inactive on LPA4/5/6. Ki values: 0.34 μM (LPA1), 0.93 μM (LPA3).</p>Fórmula:C24H25ClN2O5SPureza:98.09%Cor e Forma:SolidPeso molecular:488.98LGnRH-III, lamprey
CAS:<p>GnRH III triggers luteinizing and follicle-stimulating hormone release, part of the conserved GnRH family.</p>Fórmula:C59H74N18O14Pureza:98%Cor e Forma:SolidPeso molecular:1259.33ALEPH hydrochloride
CAS:<p>ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.</p>Fórmula:C12H20ClNO2SCor e Forma:SolidPeso molecular:277.81SB 201146
CAS:<p>SB 201146 is a leukotriene B4 antagonist with high affinity.</p>Fórmula:C30H35LiN2O5SCor e Forma:SolidPeso molecular:542.61PG106
CAS:<p>Selective hMC3 receptor antagonist (IC50 = 210 nM). Exhibits no activity at hMC4 receptors and hMC5 receptors.</p>Fórmula:C51H69N13O9Pureza:98%Cor e Forma:SolidPeso molecular:1008.19(Rac)-Norcisapride
CAS:<p>Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.</p>Fórmula:C14H20ClN3O3Pureza:99.32%Cor e Forma:SoildPeso molecular:313.78JKC363
CAS:<p>MC4 receptor antagonist; IC50: 0.5 nM (MC4), 44.9 nM (MC3). Blocks α-MSH, reduces TRH, food intake, and pain.</p>Fórmula:C69H91N19O16S2Pureza:98%Cor e Forma:SolidPeso molecular:1506.722-Furoyl-LIGRLO-amide
CAS:<p>2-Furoyl-LIGRLO-amide TFA is a peptide that acts as a proteinase-activated receptor-2 (PAR2) agonist, and contains a furoyl group addition at its N-terminal.</p>Fórmula:C36H63N11O8Pureza:98%Cor e Forma:SolidPeso molecular:777.95TRV045
CAS:<p>TRV045 is a selective agonist of the sphingosine-1-phosphate (S1P) subtype 1 receptor and does not impact lymphocyte trafficking. It possesses antiepileptic properties.</p>Fórmula:C18H18N4O3Cor e Forma:SolidPeso molecular:338.36Neuropeptide Y(29-64)
CAS:<p>Neuropeptide Y(29-64) is a 36 amino acid peptide, a fragment of Neuropeptide Y.</p>Fórmula:C189H284N54O58SPureza:98%Cor e Forma:SolidPeso molecular:4272.7Lisuride maleate
CAS:<p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>Fórmula:C24H30N4O5Pureza:99.85%Cor e Forma:SolidPeso molecular:454.52Navafenterol saccharinate
CAS:<p>AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).</p>Fórmula:C45H47N7O9S3Cor e Forma:SolidPeso molecular:926.09GLP-1 receptor agonist 13
<p>Compound (S)-9, a GLP-1 receptor agonist, exhibits an EC50 of 76 nM for the glucagon GLP-1 receptor [1].</p>Fórmula:C25H23ClF2N6OCor e Forma:SolidPeso molecular:496.941a,1b-dihomo Prostaglandin E1
CAS:<p>1a,1b-dihomo Prostaglandin E1 is a class of prostaglandin compounds.</p>Fórmula:C22H38O5Cor e Forma:SolidPeso molecular:382.541MI 1544
CAS:<p>MI 1544 is a LHRH antagonist.</p>Fórmula:C71H94ClN17O13Cor e Forma:SolidPeso molecular:1429.095-MeO-pyr-T
CAS:<p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>Fórmula:C15H20N2OCor e Forma:SolidPeso molecular:244.33NI-203
<p>NI-203 is a monoclonal antibody inhibitor that targets amylin and shows potential for research in type 2 diabetes.</p>Cor e Forma:Odour LiquidSibenadet hydrochloride
CAS:<p>Sibenadet, a D2/beta2-agonist, is potential useful for the treatment of symptoms of chronic obstructive pulmonary disease.</p>Fórmula:C22H29ClN2O5S2Cor e Forma:SolidPeso molecular:501.06Anti-TSHR Antibody (M22)
<p>Anti-TSHR Antibody (M22) is a humanized IgG1 monoclonal antibody targeting the thyroid-stimulating hormone receptor (TSHR). This antibody is capable of inhibiting the interaction between TSH and TSHR.</p>Cor e Forma:Odour LiquidLY83583
CAS:<p>LY83583 is a soluble guanylate cyclase competitive inhibitor with IC50 of 2 µM.</p>Fórmula:C15H10N2O2Pureza:99.54% - 99.80%Cor e Forma:SolidPeso molecular:250.25Paynantheine
CAS:<p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>Fórmula:C23H28N2O4Cor e Forma:SolidPeso molecular:396.48Veldoreotide
CAS:Veldoreotide (Somatoprim): a somatostatin analogue targeting receptors 2, 4, 5, reduces GH in pituitary adenomas.Fórmula:C60H74N12O10Pureza:98%Cor e Forma:SolidPeso molecular:1123.3Pal-Glu(OSu)-OH
CAS:<p>Pal-Glu(OSu)-OH is a Liraglutide side chain, a GLP-1 agonist for type 2 diabetes study.</p>Fórmula:C25H42N2O7Cor e Forma:SolidPeso molecular:482.618Parstatin(mouse)
CAS:Peptide inhibits endothelial migration/proliferation (IC50 ~20μM), induces cell cycle arrest, triggers apoptosis, and has cardioprotective effects.Fórmula:C189H326N58O57S3Pureza:98%Cor e Forma:SolidPeso molecular:4419.19Kinetensin
CAS:Kinetensin is a neurotensin-like peptide.Fórmula:C56H85N17O11Pureza:98%Cor e Forma:White Lyophilised SolidPeso molecular:1172.38PAR650097
<p>PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research.</p>Pureza:96.67% (SEC-HPLC) - 98.83% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.5kDaBA 1
CAS:<p>Potent BB1, BB2, and BB3 agonist; IC50: 0.26, 1.55, 2.52 nM. Boosts glucose transport in myocytes, promotes cancer cell growth in vitro.</p>Fórmula:C57H76N14O11Pureza:98%Cor e Forma:SolidPeso molecular:1133.32GS-2278
CAS:<p>GS-2278 is an antagonist of LPAR1 (lysophosphatidic acid receptor 1) with potential applications in the study of idiopathic pulmonary fibrosis (IPF).</p>Fórmula:C22H16F5N9O3Cor e Forma:SolidPeso molecular:549.41Cloprostenol isopropyl ester
CAS:<p>(+)-Chloprostol is a PGF2α agonist, mimics prostaglandin F2α, induces luteal dissolution in mares without side effects or stress.</p>Fórmula:C25H35ClO6Cor e Forma:SolidPeso molecular:466.99Poly-D-lysine hydrobromide (MW 150000-300000)
<p>Poly-D-lysine hydrobromide (MW 150000-300000) enhances neural cell adhesion in culture and acts as a calcium-sensing receptor agonist peptide in research.</p>Cor e Forma:Odour SolidCYM5442 hydrochloride
CAS:<p>CYM 5442 HCl: potent, selective S1P1 agonist (EC50 = 1.35 nM), induces MAPK activation & lymphopenia, brain-penetrant.</p>Fórmula:C23H28ClN3O4Cor e Forma:SolidPeso molecular:445.94Efranarelaxin alfa
CAS:<p>Efranarelaxin alfa is an agonist of the relaxin receptor. It shows potential for research in cardiovascular diseases and tissue repair.</p>Cor e Forma:Liquid5-HT2A receptor agonist-5
CAS:<p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>Fórmula:C23H29N3OCor e Forma:SolidPeso molecular:363.5[Nle11]-Substance P
CAS:<p>'[Nle11]-Substance P is a gut and brain peptide, resisting methionine oxidation and causing excitatory neural effects.'</p>Fórmula:C64H100N18O13Pureza:98%Cor e Forma:SolidPeso molecular:1329.59MrgprX2 antagonist-3
CAS:<p>MrgprX2 antagonist-3 (compound E117) is a MrgprX2 antagonist applicable for investigating cutaneous inflammation.</p>Fórmula:C16H20FN3O2SPureza:98.06%Cor e Forma:SolidPeso molecular:337.41Poly-D-lysine hydrobromide (MW 1000-5000)
<p>Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetically produced polymeric substrate widely used in neural cell culture. Additionally, Poly-D-lysine hydrobromide acts as a CaSR agonist peptide.</p>Cor e Forma:Odour Solid
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