GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(939 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.945 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(358 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5352 produtos de "GPCR/Proteína-G"
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SB 258585
CAS:<p>SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.</p>Fórmula:C18H22IN3O3SPureza:99.8%Cor e Forma:SoildPeso molecular:487.36Neuropeptide Y 13-36 (porcine)
CAS:<p>Neuropeptide Y 13-36 (porcine) is a selective neuropeptide Y2 receptor agonist.</p>Fórmula:C135H209N41O36Cor e Forma:SolidPeso molecular:2982.408Orexin B, rat, mouse
CAS:<p>Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.</p>Fórmula:C126H215N45O34SPureza:98%Cor e Forma:SolidPeso molecular:2936.45KSK67
CAS:<p>KSK67 is a selective dual antagonist of sigma-2 and histamine H3 receptors with inhibitory effects on H3 receptors, sigma-1, and sigma-2 receptors, with Ki</p>Fórmula:C22H27N3O2Pureza:99.11%Cor e Forma:SoildPeso molecular:365.47THX-B
CAS:<p>THX-B, a potent non-peptidic p75 NTR antagonist, aids in researching diabetic kidney disease and neurodegenerative and inflammatory disorders.</p>Fórmula:C16H24N6O4Cor e Forma:SolidPeso molecular:364.4Zalospirone
CAS:<p>Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.</p>Fórmula:C24H29N5O2Pureza:98.41% - 99.82%Cor e Forma:SolidPeso molecular:419.52Eletriptan
CAS:<p>Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.</p>Fórmula:C22H26N2O2SCor e Forma:SolidPeso molecular:382.52Albiglutide fragment TFA
<p>Albiglutide fragment (GLP-1 (7-36) analog) TFA represents a biologically active segment of Albiglutide, resistant to DPP-4 degradation due to its structure as a</p>Fórmula:C148H224N40O45·xC2HF3O2Cor e Forma:SolidCB2R/FAAH modulator-2
CAS:<p>CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH.</p>Fórmula:C24H33NO2Pureza:99.15%Cor e Forma:SoildPeso molecular:367.52H4R antagonist 3
CAS:<p>H4R antagonist 3 is a novel histamine-4 receptor (H4R) antagonist with an EC50 <10 mM.H4R antagonist 3 has potential inflammatory activity for the study of</p>Fórmula:C19H21ClN4SPureza:98%Cor e Forma:SolidPeso molecular:372.92Imnopitant dihydrochloride
CAS:<p>Imnopitant dihydrochloride is a neurokinin NK1 receptor antagonist [1] .</p>Fórmula:C28H30Cl2F6N4OCor e Forma:SolidPeso molecular:623.46AB21 HCl
<p>AB21 HCl: σ1 receptor antagonist, Ki 13 nM; less potent at σ2 (102 nM). Reduces mechanical hypersensitivity.</p>Fórmula:C23H29ClN2OPureza:99.91%Cor e Forma:SolidPeso molecular:384.2Substance P (1-9)
CAS:<p>Substance P (1-9), a nonapeptide, slows its own inactivation and stimulates neurons.</p>Fórmula:C52H77N15O12Pureza:98%Cor e Forma:SolidPeso molecular:1104.26Oxmetidine
CAS:<p>Oxmetidine (SKF 92994) is an H2R antagonist that inhibits transmembrane calcium flux in the cardiovascular system and is used in the study of duodenal ulcers.</p>Fórmula:C19H21N5O3SPureza:99.67%Cor e Forma:SolidPeso molecular:399.47(Iso)-RJW100
CAS:<p>Potent LRH-1/NR5A2 and SF-1/NR5A1 agonist; pEC50: 6.4 (LRH-1), 7.2 (SF-1).</p>Fórmula:C28H34OPureza:99.79%Cor e Forma:SoildPeso molecular:386.57Blue FPG-A trisodium
CAS:<p>Blue FPG-A trisodium is a P2X1 & P2Y1 receptor antagonist, IC50: 35.5 μM & 2.6 μM, related to RB2.</p>Fórmula:C29H17ClN7Na3O11S3Cor e Forma:SolidPeso molecular:840.1IRL-1038 acetate
<p>IRL-1038 acetate is a potent ETB endothelin receptor antagonist.</p>Fórmula:C70H96N14O17S2Pureza:97.51%Cor e Forma:SoildPeso molecular:1469.73Adrenomedullin (16-31), human
CAS:<p>Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM).</p>Fórmula:C82H129N25O21S2Pureza:98%Cor e Forma:SolidPeso molecular:1865.19Bradykinin (1-6)
CAS:<p>Bradykinin (1-6) is a stable, CPY-cleaved metabolite that triggers pain, induces muscle contractions, and activates NO synthetase.</p>Fórmula:C30H45N9O8Pureza:98%Cor e Forma:SolidPeso molecular:659.73M1145
CAS:<p>Potent GAL2 agonist with EC50 = 38 nM; Ki: 6.55 nM (GAL2), 497 nM (GAL3), 587 nM (GAL1); enhances galanin signaling.</p>Fórmula:C128H205N37O32Pureza:98%Cor e Forma:SolidPeso molecular:2774.26Lys-γ3-MSH(human)
CAS:<p>Pro-opiomelanocortin (POMC) derived peptide that stimulates lipolysis</p>Fórmula:C128H193N45O39SPureza:98%Cor e Forma:SolidPeso molecular:3018.25Orexin A (human, rat, mouse) (TFA)
Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.Fórmula:C154H244N47F3O46S4Pureza:98%Cor e Forma:SolidPeso molecular:3675.12Urocortin III, mouse
CAS:<p>Mouse UcnIII, linked to stress behaviors, mainly occurs in the brain and rises in the hypothalamus post-restraint.</p>Fórmula:C186H312N52O52S2Pureza:98%Cor e Forma:SolidPeso molecular:4172.97BIBP3226
CAS:<p>BIBP3226 is a potent and selective antagonist for the Neuropeptide Y receptor Y1 and the neuropeptide FF receptor.</p>Fórmula:C27H31N5O3Cor e Forma:SolidPeso molecular:473.57Apadenoson TFA
<p>Apadenoson TFA is a potent adenosine A2A receptor (A2AR) agonist that can be used to improve survival in patients infected with SARS.</p>Fórmula:C25H31F3N6O8Pureza:98.08%Cor e Forma:SoildPeso molecular:600.555-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Fórmula:C13H18N2OPureza:98.25%Cor e Forma:SolidPeso molecular:218.29S(-)-Bisoprolol fumarate
CAS:<p>S(-)-Bisoprolol fumarate is a selective β1-blocker for hypertension and heart research.</p>Fórmula:C18H31NO4·xC4H4O4Cor e Forma:SolidPeso molecular:441.521QWF
CAS:<p>Tripeptide SP antagonist (IC50: 90 μM); blocks SP-MRGPR X2 binding and mast cell degranulation; reduces 48/80-induced scratching in mice.</p>Fórmula:C38H43N5O8Pureza:98%Cor e Forma:SolidPeso molecular:697.78CCR4 antagonist 3 hydrochloride
CAS:<p>Orally active CCR4 antagonist 3 hydrochloride with potent selectivity, IC50s: 22/50 nM; has antitumor properties.</p>Fórmula:C24H27Cl2N7O·xHClCor e Forma:SolidThiothixene
CAS:<p>Thiothixene has a wide range of applications in life science related research.</p>Fórmula:C23H29N3O2S2Cor e Forma:SolidPeso molecular:443.62GRK-IN-1
CAS:<p>4-Amino-5-(bromomethyl)-2-methylpyrimidine used in vitamin B1 analogs and esters synthesis.</p>Fórmula:C6H10Br3N3Cor e Forma:SolidPeso molecular:363.8792,6-DMA hydrochloride
CAS:<p>2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.</p>Fórmula:C11H18ClNO2Cor e Forma:SolidPeso molecular:231.725-Bromoimidazo[1,2-A]Pyrazine
CAS:<p>5-Bromoimidazo[1,2-a]pyrazine inhibits phosphodiesterase and beta-adrenergic receptors.5-Bromoimidazo[1,2-a]pyrazine shows antibronchospastic activity in vitro.</p>Fórmula:C6H4BrN3Pureza:97.04%Cor e Forma:SolidPeso molecular:198.02Heterobivalent ligand-1
<p>Heterobivalent ligand-1 targets A2A-D2 receptor heteromer with affinity: Kd for A2A=2.1 nM, D2=0.13 nM.</p>Fórmula:C86H115FN16O21Cor e Forma:SolidPeso molecular:1727.93GHRF, porcine
CAS:<p>GHRF, porcine, a growth hormone releasing factor (GHRF) peptide (porcine), binds to the growth hormone secretagogue receptor (GHSR), thereby inducing the</p>Fórmula:C219H365N73O66SCor e Forma:SolidPeso molecular:5108.76CAY10606
CAS:<p>CAY10606 has a wide range of applications in life science related research.</p>Fórmula:C22H18ClNO3Cor e Forma:SolidPeso molecular:379.84Icatibant
CAS:<p>Icatibant is a selective and specific antagonist of the bradykinin B2 receptor (IC50 and Ki: 1.07 nM and 0.798 nM respectively).</p>Fórmula:C59H89N19O13SPureza:98%Cor e Forma:White SolidPeso molecular:1304.52ABT-702
CAS:<p>ABT-702 is an orally active, competitive, and reversible non-nucleoside adenosine kinase (AK) inhibitor analgesic and anti-inflammatory.</p>Fórmula:C22H19BrN6OPureza:99.57%Cor e Forma:SoildPeso molecular:463.334-fluoro MBZP
CAS:<p>4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.</p>Fórmula:C12H17FN2Cor e Forma:SolidPeso molecular:208.28O-Desethyl Dapagliflozin
CAS:<p>O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.</p>Fórmula:C19H21ClO6Pureza:98.33%Cor e Forma:SolidPeso molecular:380.82MR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Fórmula:C22H28ClN3O2Peso molecular:401.18716-phenoxy tetranor Prostaglandin F2α methyl ester
CAS:<p>Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.</p>Fórmula:C23H32O6Cor e Forma:SolidPeso molecular:404.503ethyl 1-[(4-cyanobenzyl)oxy]-2-(3-cyanophenyl)-4-methyl-1H-imidazole-5-carboxylate
CAS:<p>ethyl 1-[(4-cyanobenzyl)oxy]-2-(3-cyanophenyl)-4-methyl-1H-imidazole-5-carboxylate is a platelet aggregation inhibitor.</p>Fórmula:C22H18N4O3Pureza:99.86%Cor e Forma:SolidPeso molecular:386.4(R)-Preclamol hydrochloride
CAS:<p>(R)-Preclamol HCl is a dopamine agonist stimulating both auto and postsynaptic receptors.</p>Fórmula:C14H22ClNOCor e Forma:SolidPeso molecular:255.78Fabesetron
CAS:<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Fórmula:C18H19N3OCor e Forma:SolidPeso molecular:293.37Bodilisant
CAS:<p>Bodilisant: nanomolar-affinity hH3R ligand, derived from piperidine, with BODIPY fluorophore.</p>Fórmula:C27H34BF2N3OCor e Forma:SolidPeso molecular:465.4Hemokinin 1, human
CAS:<p>Endogenous P-like compound, NK1 receptor agonist; IC50: NK1-1.8 nM, NK3-370 nM, NK2-480 nM; boosts B-cell growth, antiapoptotic, lowers blood pressure in vivo.</p>Fórmula:C54H84N14O14SPureza:98%Cor e Forma:SolidPeso molecular:1185.4AGN 191976
CAS:<p>AGN 191976 is a novel thromboxane A2-mimetic.</p>Fórmula:C21H32O6Cor e Forma:SolidPeso molecular:380.481HAEGTFTSDVS acetate
<p>HAEGTFTSDVS acetate is the first N-terminal 1-11 residues of GLP-1 which stimulates insulin secretion from pancreatic β-cells.</p>Fórmula:C50H75N13O22Pureza:97.47%Cor e Forma:SolidPeso molecular:1210.2LY 344864 racemate
CAS:<p>LY 344864 racemate is a 5-HT1F receptor agonist.</p>Fórmula:C21H22FN3OPureza:99.75%Cor e Forma:SoildPeso molecular:351.42
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