GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(939 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.945 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(358 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5352 produtos de "GPCR/Proteína-G"
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AC-263093
CAS:<p>AC-263093 is an NPFFR2 agonist with anxiolytic activity that increases c-Fos protein expression in the paraventricular nucleus of the hypothalamus.</p>Fórmula:C8H8Br2N4Pureza:99.78%Cor e Forma:SoildPeso molecular:319.98Jatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Fórmula:C20H21NO5Cor e Forma:SolidPeso molecular:355.38DSP-1053
CAS:<p>Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.</p>Fórmula:C26H32BrNO4Pureza:98%Cor e Forma:SolidPeso molecular:502.44Preclamol hydrochloride
CAS:<p>Preclamol hydrochloride: selective dopamine agonist with research potential in schizophrenia.</p>Fórmula:C14H22ClNOCor e Forma:SolidPeso molecular:255.78NPFF2-R ligand 1
<p>NPFF2-R ligand 1 (Compound 16a) is an NPFF2-R ligand with Ki values of 228 nM for NPFF1-R and 27 nM for NPFF2-R, and can be utilized in research on central nervous system-related disorders.</p>Fórmula:C32H41N3OPeso molecular:483.32496CAY10580
CAS:<p>CAY10580 is a potent and selective prostaglandin EP 4 receptor agonist ( K i =35 nM).</p>Fórmula:C19H35NO4Cor e Forma:SolidPeso molecular:341.49Acetyl-Amylin (8-37) (human)
CAS:<p>Acetyl-Amylin (8-37) (human) is a specific amylin antagonist [1] .</p>Fórmula:C140H218N42O46Cor e Forma:SolidPeso molecular:3225.48Melanostatin, frog
CAS:<p>Melanostatin, frog, is an inhibitor of α-melanocyte-stimulating hormone (α-MSH) release, with an IC50 of 60 nM [1] [2].</p>Fórmula:C189H285N53O57SCor e Forma:SolidPeso molecular:4243.67Obestatin(rat)
CAS:<p>Endogenous peptide that suppresses food intake and body weight-gain</p>Fórmula:C114H174N34O31Pureza:98%Cor e Forma:SolidPeso molecular:2516.81Peptide YY (PYY) (3-36), porcine TFA
<p>Peptide YY (PYY) (3-36), porcine TFA, functions as a gut hormone that serves as a Y2 receptor agonist, effectively reducing appetite [1].</p>Fórmula:C176H272N52O54·C2HF3O2Cor e Forma:SolidPeso molecular:4094.44(3R,5R,6S)-Atogepant
<p>(3R,5R,6S)-Atogepant (MK-8031) is a CGRP antagonist enantiomer used in migraine research.</p>Fórmula:C29H23F6N5O3Cor e Forma:SolidPeso molecular:603.52S 16474
CAS:<p>S 16474 is an antagonist of Neurokinin-1 Receptor.</p>Fórmula:C44H48N6NaO8Pureza:98%Cor e Forma:SolidPeso molecular:811.892Imelciment
CAS:<p>Imelciment (REGN-9035) is a humanised monoclonal antibody targeting NPR1, which can be used for research into heart failure.</p>Pureza:95%Cor e Forma:Soild11-deoxy Prostaglandin E2
CAS:<p>11-deoxy PGE2 is a synthetic PGE2 analog, a potent bronchoconstrictor, 5-30x stronger than PGF2α on human respiratory muscles.</p>Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.47Cetirizine methyl ester
CAS:<p>Cetirizine methyl ester is a Cetirizine impurity, a long-acting, oral H1-antihistamine and hydroxyzine metabolite.</p>Fórmula:C22H27ClN2O3Cor e Forma:SolidPeso molecular:402.91L-803087 TFA
CAS:<p>L-803087 TFA: potent sst4 agonist, Ki=0.7 nM, >280x selective vs other somatostatin receptors; boosts AMPA, heightens seizures.</p>Fórmula:C27H30F5N5O5Cor e Forma:SolidPeso molecular:599.55(+)-OSU 6162
CAS:<p>(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.</p>Fórmula:C15H23NO2SPureza:98.19%Cor e Forma:SoildPeso molecular:281.41M871
CAS:<p>GAL2 receptor antagonist; Ki: 13.1 nM (GAL2), 420 nM (GAL1); inhibits GAL2-induced pain.</p>Fórmula:C108H163N27O28Pureza:98%Cor e Forma:SolidPeso molecular:2287.64Protease-Activated Receptor-1 antagonist 2
CAS:<p>Orally active PAR-1 antagonist with 7 nM IC50; potential for CVD research.</p>Fórmula:C24H23F2N3O2Cor e Forma:SolidPeso molecular:423.46Chir 2279
CAS:<p>CHIR 2279, a peptoid trimer, binds alpha 1-adrenoceptors, blocking epinephrine effects in dogs (pseudo pA2 6.86).</p>Fórmula:C34H36N4O4Cor e Forma:SolidPeso molecular:564.67Ilatreotide
CAS:<p>Ilatreotide is a Amadori compound of octreotide.</p>Fórmula:C61H86N10O20S2Pureza:98%Cor e Forma:SolidPeso molecular:1343.53PSB 0777 ammonium salt
CAS:<p>adenosine A2A receptor full agonist</p>Fórmula:C18H24N6O7S2Pureza:98%Cor e Forma:SolidPeso molecular:500.55Poly-D-lysine hydrobromide (MW 1000-5000)
<p>Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetically produced polymeric substrate widely used in neural cell culture. Additionally, Poly-D-lysine hydrobromide acts as a CaSR agonist peptide.</p>Cor e Forma:Odour SolidCB2R probe 1
CAS:<p>CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of</p>Fórmula:C36H42N4O4Cor e Forma:SolidPeso molecular:594.74CRF(6-33)(human)
CAS:<p>CRFBP inhibitor peptide; blocks CRF, reduces weight gain, boosts activity in obese rats.</p>Fórmula:C141H231N41O43SPureza:98%Cor e Forma:SolidPeso molecular:3220.68AY 254
CAS:<p>AY 254: Potent PAR2 agonist, ERK1/2 activation (EC50=2 nM), limits caspase 3/8, aids HT29 cell healing, boosts IL-8.</p>Fórmula:C30H49N9O6Cor e Forma:SolidPeso molecular:631.779OXA(17-33)
CAS:<p>Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.</p>Fórmula:C79H125N23O22Pureza:98%Cor e Forma:SolidPeso molecular:1749LP 12 hydrochloride
CAS:<p>LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).</p>Fórmula:C32H40ClN3OCor e Forma:SolidPeso molecular:518.14Efranarelaxin alfa
CAS:<p>Efranarelaxin alfa is an agonist of the relaxin receptor. It shows potential for research in cardiovascular diseases and tissue repair.</p>Cor e Forma:LiquidMrgprX2 antagonist-2
CAS:<p>MrgprX2 antagonist-2, from patent WO2021092262A1 E163, is potent for skin inflammation studies.</p>Fórmula:C17H16F5N3O3Cor e Forma:SolidPeso molecular:405.325GLP-1R agonist 4
CAS:<p>GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.</p>Fórmula:C32H30ClF2N3O5Cor e Forma:SolidPeso molecular:610.05Brexpiprazole S-oxide D8
CAS:<p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>Fórmula:C25H19D8N3O3SPureza:98%Cor e Forma:SolidPeso molecular:457.61(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
CAS:<p>Analog of LHRH, stimulates LH and FSH release, controls reproduction.</p>Fórmula:C59H84N18O14Cor e Forma:SolidPeso molecular:1269.41[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
CAS:<p>Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage.</p>Fórmula:C50H75N15O10Pureza:98%Cor e Forma:SolidPeso molecular:1046.23FR 113680
CAS:<p>FR 113680 is a tripeptide substance P antagonist with NK1 receptor selectivity.</p>Fórmula:C35H39N5O6Pureza:98%Cor e Forma:SolidPeso molecular:625.726BAY-6672 hydrochloride
CAS:<p>BAY-6672 hydrochloride is a potent, selective antagonist of the human Prostaglandin F (FP) receptor, exhibiting an IC50 value of 11 nM.</p>Fórmula:C26H28BrCl2N3O3Cor e Forma:SolidPeso molecular:581.33TAK-683 acetate
<p>TAK-683 acetate: potent KISS1R agonist (IC50=170 pM), stable, nonapeptide. Affects GnRH, FSH, LH, testosterone; potential in prostate cancer research.</p>Fórmula:C66H87N17O15Cor e Forma:SolidPeso molecular:1358.5N-0500 HCl
CAS:<p>N-0500 HCl, a potent DA receptor agonist, displaces [3H]DP_x005f_x0002_5,6-ADTN with an IC50 of 3nM.</p>Fórmula:C15H22ClNO2Pureza:98.85% - 99.54%Cor e Forma:SolidPeso molecular:283.79QWF
CAS:<p>Tripeptide SP antagonist (IC50: 90 μM); blocks SP-MRGPR X2 binding and mast cell degranulation; reduces 48/80-induced scratching in mice.</p>Fórmula:C38H43N5O8Pureza:98%Cor e Forma:SolidPeso molecular:697.78Roxatidine
CAS:<p>Roxatidine, a metabolite of Roxatidine acetate, is a H2-receptor antagonist that prevents ulcers and has anti-inflammatory properties.</p>Fórmula:C17H26N2O3Cor e Forma:SolidPeso molecular:306.4RC-3095
CAS:<p>RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.</p>Fórmula:C56H79N15O9Pureza:98%Cor e Forma:SolidPeso molecular:1106.32Baloncibart
CAS:<p>Baloncibart is a human IgG4K monoclonal antibody that targets NPR1.</p>Cor e Forma:LiquidBradykinin (1-3)
CAS:<p>Bradykinin (1-3) is a fragment of Bradykinin. Bradykinin is an activates pain receptors.</p>Fórmula:C16H28N6O4Pureza:98%Cor e Forma:SolidPeso molecular:368.43AZP-531
CAS:<p>Azp-531 is a disacylated ghrelin used to improve blood sugar control and weight loss.</p>Fórmula:C40H63N15O13Pureza:98%Cor e Forma:SolidPeso molecular:962.02Galcanezumab
CAS:<p>Galcanezumab: humanized IgG4 antibody that targets CGRP for migraine and cluster headache prevention/treatment.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:144.08 kDaGLI1-IN-3
<p>GLI1-IN-3 (Compound 11a) is a triterpenoid-like compound that inhibits Hedgehog signaling in cancer cells with GLI1 overexpression. It suppresses the proliferation of non-small cell lung cancer and prostate cancer cell lines with excessive Hh signaling activation. Additionally, GLI1-IN-3 reduces the expression of GLI1 protein and its target genes associated with tumor progression and proliferation in A549 and DU-145 cancer cells.</p>Cor e Forma:Odour SolidBremelanotide
CAS:<p>Bremelanotide is a synthetic peptide analog of alpha-MSH and is an agonist at melanocortin receptors including the MC3R and MC4R.</p>Fórmula:C50H68N14O10Pureza:98%Cor e Forma:White PowderPeso molecular:1025.16Lys-[Des-Arg9]Bradykinin
CAS:Selective bradykinin B1 agonist with Ki 0.12 nM; inactive at B2 (>30,000 nM). Lowers blood pressure, more potent than Des-Arg9-Bradykinin.Fórmula:C50H73N13O11Pureza:98%Cor e Forma:SolidPeso molecular:1032.21M617
CAS:<p>Galanin GAL1 agonist, Ki: GAL1 0.23 nM, GAL2 5.71 nM; boosts rat appetite, lessens inflammation pain.</p>Fórmula:C112H161N29O28Pureza:98%Cor e Forma:SolidPeso molecular:2361.68α-CGRP(human) TFA
<p>α-CGRP(human) TFA is a 37-amino acid regulatory neuropeptide that is extensively located within the central and peripheral nervous system, functioning as a</p>Fórmula:C165H268F3N51O51S2Cor e Forma:SolidPeso molecular:3903.33
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