GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(939 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.945 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(358 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5352 produtos de "GPCR/Proteína-G"
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HAEGTFTSDVS
CAS:<p>HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.</p>Fórmula:C48H71N13O20Pureza:98%Cor e Forma:SolidPeso molecular:1150.181,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Fórmula:C10H18OPureza:97.44% - 97.44%Cor e Forma:SolidPeso molecular:154.25Misoprostol acid
CAS:<p>Misoprostol acid is an active metabolite of Misoprostol,can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers.</p>Fórmula:C21H36O5Pureza:98%Cor e Forma:SolidPeso molecular:368.51IRL-3630
CAS:<p>IRL 3460 is an enantiomer.</p>Fórmula:C31H40N4O6SPureza:98%Cor e Forma:SolidPeso molecular:596.74Pal-Glu(OSu)-OH
CAS:<p>Pal-Glu(OSu)-OH is a Liraglutide side chain, a GLP-1 agonist for type 2 diabetes study.</p>Fórmula:C25H42N2O7Cor e Forma:SolidPeso molecular:482.618Parstatin(mouse)
CAS:<p>Peptide inhibits endothelial migration/proliferation (IC50 ~20μM), induces cell cycle arrest, triggers apoptosis, and has cardioprotective effects.</p>Fórmula:C189H326N58O57S3Pureza:98%Cor e Forma:SolidPeso molecular:4419.19Pancreatic Polypeptide, bovine
CAS:<p>Agonist at Y4 neuropeptide Y receptors.</p>Fórmula:C186H287N53O56S2Pureza:98%Cor e Forma:SolidPeso molecular:4225.78Kinetensin
CAS:<p>Kinetensin is a neurotensin-like peptide.</p>Fórmula:C56H85N17O11Pureza:98%Cor e Forma:White Lyophilised SolidPeso molecular:1172.38Amylin, amide, rat
CAS:<p>Amylin: peptide, 50% similar to CGRP, found with somatostatin in stomach cells, reduces acid secretion in mice.</p>Fórmula:C167H272N52O53S2Pureza:99.92%Cor e Forma:SolidPeso molecular:3920.44Apraglutide
CAS:<p>Apraglutide (FE 203799 is a synthetic 33-amino acid peptide and long-acting glp-2 analogue.</p>Fórmula:C172H263N43O52Pureza:98%Cor e Forma:SolidPeso molecular:3765.25SHU 9119
CAS:<p>SHU 9119 is a potent antagonist for human MC3R/MC4R and partial agonist for MC5R with IC50 values of 0.23, 0.06, 0.09 nM.</p>Fórmula:C54H71N15O9Pureza:98%Cor e Forma:SolidPeso molecular:1074.258PACAP-38 (16-38), human, mouse, rat
CAS:<p>PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production</p>Fórmula:C123H215N39O28SPureza:98%Cor e Forma:SolidPeso molecular:2720.33Vanicoside E
CAS:<p>Vanicoside E is an antioxidant and antitumor agent. Vanicoside E inhibits L-Tyrosine and L-DOPA with IC 50 s of 45.23 μM and 189.96 μM, respectively [1] [2] .</p>Fórmula:C53H52O22Cor e Forma:SolidPeso molecular:1040.9711β-Prostaglandin E2
CAS:<p>11β-PGE2 is the C-11 epimer of PGE2.</p>Fórmula:C20H32O5Cor e Forma:SolidPeso molecular:352.47RFRP-3(human)
CAS:<p>NPFF1 receptor agonist, IC50 0.7 nM, blocks cAMP by forskolin. A GnIH homolog, it inhibits GnRH neuron activity.</p>Fórmula:C45H72N14O10Pureza:98%Cor e Forma:SolidPeso molecular:969.15Semaglutide TFA
<p>Semaglutide TFA is a glucagon-like peptide-1 congener that induces weight loss, lowers blood glucose levels and reduces cardiovascular risk in diabetic patients</p>Fórmula:C189H290F3N45O61Pureza:99.69%Cor e Forma:SolidPeso molecular:4225.6482Stressin I
<p>Potent CRF1 agonist; Ki: 1.5 nM (CRF1), 224 nM (CRF2). Boosts ACTH, enhances stool frequency after i.p. administration.</p>Fórmula:C203H337N57O56Pureza:98%Cor e Forma:SolidPeso molecular:4472.24Methicillin sodium hydrate
CAS:<p>Methicillin sodium hydrate, a narrow-spectrum antibiotic, combats methicillin-resistant Staphylococcus strains and treats various infections.</p>Fórmula:C17H21N2NaO7SCor e Forma:SolidPeso molecular:420.41TGR5 agonist 2
<p>TGR5 agonist 2 (compound 19) serves as a highly potent agonist of TGR5, demonstrating an EC50 value of 0.27 µM [1].</p>Fórmula:C29H50NNaO6SCor e Forma:SolidPeso molecular:563.7713,14-dihydro-15-keto Prostaglandin F1α
CAS:<p>13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach.</p>Fórmula:C20H36O5Cor e Forma:SolidPeso molecular:356.5LY 293284
CAS:<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Fórmula:C19H26N2OCor e Forma:SolidPeso molecular:298.42Zicronapine fumarate
CAS:<p>Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.</p>Fórmula:C26H31ClN2O4Cor e Forma:SolidPeso molecular:470.99Ghrelin receptor full agonist-2
CAS:<p>Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist.</p>Fórmula:C26H28ClN5O5SCor e Forma:SolidPeso molecular:558.05Heterobivalent ligand-1
<p>Heterobivalent ligand-1 targets A2A-D2 receptor heteromer with affinity: Kd for A2A=2.1 nM, D2=0.13 nM.</p>Fórmula:C86H115FN16O21Cor e Forma:SolidPeso molecular:1727.93Adrenomedullin (16-31), human
CAS:<p>Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM).</p>Fórmula:C82H129N25O21S2Pureza:98%Cor e Forma:SolidPeso molecular:1865.19Chir 2279
CAS:<p>CHIR 2279, a peptoid trimer, binds alpha 1-adrenoceptors, blocking epinephrine effects in dogs (pseudo pA2 6.86).</p>Fórmula:C34H36N4O4Cor e Forma:SolidPeso molecular:564.67Cetirizine methyl ester
CAS:<p>Cetirizine methyl ester is a Cetirizine impurity, a long-acting, oral H1-antihistamine and hydroxyzine metabolite.</p>Fórmula:C22H27ClN2O3Cor e Forma:SolidPeso molecular:402.91Roxatidine
CAS:<p>Roxatidine, a metabolite of Roxatidine acetate, is a H2-receptor antagonist that prevents ulcers and has anti-inflammatory properties.</p>Fórmula:C17H26N2O3Cor e Forma:SolidPeso molecular:306.4RWJ 676070
CAS:<p>RWJ 676070 is an antagonist of vasopressin V1A/V2 receptor.</p>Fórmula:C30H26ClFN2O5Cor e Forma:SolidPeso molecular:548.99Pancreatic Polypeptide, rat
CAS:<p>Rat Pancreatic Polypeptide: 36-amino acid peptide, NPYR4 agonist, secreted by islet PP cells.</p>Fórmula:C195H298N58O57SPureza:98%Cor e Forma:SolidPeso molecular:4398.87Bremelanotide
CAS:<p>Bremelanotide is a synthetic peptide analog of alpha-MSH and is an agonist at melanocortin receptors including the MC3R and MC4R.</p>Fórmula:C50H68N14O10Pureza:98%Cor e Forma:White PowderPeso molecular:1025.16Pentagastrin meglumine
CAS:<p>Pentagastrin meglumine is a synthetic pentapeptide that has effects like gastrin when given parenterally.</p>Fórmula:C44H66N8O14SCor e Forma:SolidPeso molecular:963.11ONO-8711
CAS:<p>ONO-8711 is a potent and selective competitive antagonist of EP1 receptor with Kis of 0.6 nM and 1.7 nM for human and mouse EP1, respectively.</p>Fórmula:C22H30ClNO4SCor e Forma:SolidPeso molecular:440Antipsychotic agent-2
<p>Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.</p>Fórmula:C22H26FN5OCor e Forma:SolidPeso molecular:395.47Hemopressin(rat)
CAS:<p>Peptide inhibitor for ep24.15, neurolysin & ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain & food intake.</p>Fórmula:C53H77N13O12Pureza:98%Cor e Forma:SolidPeso molecular:1088.27Cetirizine Impurity C dihydrochloride
CAS:<p>Cetirizine Impurity C dihydrochloride is a Cetirizine metabolite and long-acting H1-antihistamine.</p>Fórmula:C21H27Cl3N2O3Cor e Forma:SolidPeso molecular:461.81Galanin (1-29)(rat, mouse)
CAS:<p>Non-selective galanin agonist; Ki: GAL1-0.98, GAL2-1.48, GAL3-1.47 nM. Anticonvulsant, stops full seizures in rats.</p>Fórmula:C141H211N43O41Pureza:98%Cor e Forma:White Lyophilized PowderPeso molecular:3164.499FR252384
CAS:<p>FR252384 is an antagonist of the neuropeptide Y-Y5 receptor (IC50: 2.3 nM).</p>Fórmula:C18H17N3Pureza:98%Cor e Forma:SolidPeso molecular:275.35VU0453379 hydrochloride
<p>VU0453379 hydrochloride: selective CNS-penetrant GLP-1R PAM, EC50 1.3 μM.</p>Fórmula:C26H35ClN4O2Cor e Forma:SolidPeso molecular:471.03ACTH (1-17)
CAS:<p>ACTH (1-17), a potent MC1 receptor agonist with a Ki of 0.21 nM, is a variant of corticotropin from the pituitary gland.</p>Fórmula:C95H145N29O23SPureza:98%Cor e Forma:SolidPeso molecular:2093.41Neuropeptide Y (22-36)
CAS:<p>Neuropeptide Y (22-36) is a 15-amino acid fragment of NPY, which is abundant in the mammalian brain and involved in multiple physiological functions.</p>Fórmula:C85H139N29O21Pureza:98%Cor e Forma:SolidPeso molecular:1903.19Motilin, canine
CAS:<p>Motilin canine, a 22-amino acid peptide, functions as a robust gastrointestinal smooth muscle contraction agonist.</p>Fórmula:C120H194N36O34Pureza:98%Cor e Forma:SolidPeso molecular:2685.05Tocrifluor T1117
CAS:<p>Fluorescent form of AM 251, CB1 receptor antagonist</p>Fórmula:C56H53Cl2N7O5Pureza:98%Cor e Forma:SolidPeso molecular:974.974-Butyl-α-agarofuran
CAS:<p>4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.</p>Fórmula:C18H30OCor e Forma:SolidPeso molecular:262.43PEN (rat)
CAS:<p>PEN (rat) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.</p>Fórmula:C102H169N27O33Pureza:98%Cor e Forma:SolidPeso molecular:2301.62Metaterol
CAS:<p>Metaterol is a bioactive chemical.</p>Fórmula:C11H17NO2Cor e Forma:SolidPeso molecular:195.2582Satavaptan
CAS:<p>Satavaptan is a vasopressin V2 receptor antagonist. Satavaptan improves the control of ascites in cirrhosis.</p>Fórmula:C33H45N3O8SCor e Forma:SolidPeso molecular:643.79Rhazimine
CAS:<p>Rhazimine is an indole alkaloid. It is a dual inhibitor of arachidonic acid metabolism and platelet activating factor-induced platelet aggregation.</p>Fórmula:C21H22N2O3Cor e Forma:SolidPeso molecular:350.418Oxyntomodulin
CAS:<p>GLP-1 analog modulates appetite, boosts metabolism, and curbs gastric acid. Increases cAMP, mildly stimulates glucagon receptor.</p>Fórmula:C192H295N59O60SPureza:98%Cor e Forma:SolidPeso molecular:4421.86GLP-1(7-37)
CAS:<p>GLP-1 (7-37) is a truncated, bioactive form of GLP-1 that is the product of proglucagon processing in intestinal endocrine L cells.</p>Fórmula:C151H228N40O47Pureza:98%Cor e Forma:SolidPeso molecular:3355.67
