GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.949 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5378 produtos de "GPCR/Proteína-G"
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ACTH (34-39)
CAS:ACTH (34-39) is an adrenocorticotropic hormone fragment.Fórmula:C37H50N6O9Pureza:98%Cor e Forma:SolidPeso molecular:722.83Mitemcinal fumarate
CAS:<p>Mitemcinal fumarate is a erythromycin derivative that is used to treat gastroesophageal reflux disease.</p>Fórmula:C84H142N2O28Cor e Forma:SolidPeso molecular:1628.02Mirtazapine N-oxide
CAS:<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Fórmula:C17H19N3OCor e Forma:SolidPeso molecular:281.359AC-178335
CAS:<p>AC-178335: SRIF antagonist, Ki=172 nM, inhibits SRIF's adenylate cyclase effects (IC50=5.1 µM), triggers GH release in rats.</p>Fórmula:C49H63N13O7Cor e Forma:SolidPeso molecular:946.11(+)-5-trans Cloprostenol
CAS:<p>Cloprostenol, a synthetic PGF2α derivative, induces estrus and treats reproductive issues in livestock; its minor impurity, (+)-5-trans, is less effective.</p>Fórmula:C22H29ClO6Cor e Forma:SolidPeso molecular:424.92Ularitide
CAS:<p>Ularitide is a 32-amino acid peptide from ANP prohormone, resistant to dog kidney cortex peptidase.</p>Fórmula:C145H234N52O44S3Pureza:98%Cor e Forma:SolidPeso molecular:3505.97(+)-ORM-10921
CAS:<p>(+)-ORM-10921 is a conformation of ORM-10921 and can be used in chemical synthesis studies.</p>Fórmula:C18H23NO2Pureza:99.85%Cor e Forma:SoildPeso molecular:285.386α-Prostaglandin I1
CAS:<p>6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions.</p>Fórmula:C20H34O5Cor e Forma:SolidPeso molecular:354.487Nocistatin(human)
CAS:<p>Blocker of nociceptin-induced allodynia and hyperalgesia</p>Fórmula:C149H238N42O53S3Pureza:98%Cor e Forma:SolidPeso molecular:3561.93L-779976
CAS:<p>L-779,976 is an agonist of somatostatin receptor.</p>Fórmula:C33H43N7O3Cor e Forma:SolidPeso molecular:585.74LysoPalloT-NH-amide-C3-ph-m-O-C11
CAS:<p>LysoPalloT-NH-amide-C3-ph-m-O-C11 is an agonist of the GPR174 receptor with an EC50 value of 34 nM.</p>Fórmula:C27H47N2O9PCor e Forma:SolidPeso molecular:574.64Tafluprost ethyl amide
CAS:<p>Tafluprost ethyl amide is a prostaglandin derivative.</p>Fórmula:C24H33F2NO4Cor e Forma:SolidPeso molecular:437.52Jmv 179
CAS:<p>Jmv 179 is an antagonist of the cholecystokinin receptor.</p>Fórmula:C51H67N7O15SCor e Forma:SolidPeso molecular:1050.19TLX agonist 2
<p>TLX agonist 2 (compound 31) is a TLX agonist with an EC50 of 0.1 μM and a Kd of 0.16 μM. This compound enhances transcriptional activity by binding to TLX, thereby boosting the expression of TLX target genes. TLX agonist 2 is utilized in research on neurodegenerative diseases.</p>Cor e Forma:Odour SolidAvorelin
CAS:<p>Avorelin, a luteinizing hormone releasing hormone (LH-RH) agonist, is used potentially for the treatment of prostate.</p>Fórmula:C65H85N17O12Pureza:98%Cor e Forma:SolidPeso molecular:1296.48CAY10734
CAS:<p>CAY10734 has a wide range of applications in life science related research.</p>Fórmula:C23H25N3O3Cor e Forma:SolidPeso molecular:391.4715-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Fórmula:C13H18N2OPureza:98.25%Cor e Forma:SolidPeso molecular:218.29Thiothixene
CAS:<p>Thiothixene has a wide range of applications in life science related research.</p>Fórmula:C23H29N3O2S2Cor e Forma:SolidPeso molecular:443.62Galanin-Like Peptide (human)
CAS:<p>Galanin-Like Peptide (human) is a neuropeptide consisting of 60 amino acids, instrumental in regulating feeding, body weight, and energy metabolism [1].</p>Fórmula:C292H451N83O84SPureza:98%Cor e Forma:SolidPeso molecular:6500.28Jmv 167
CAS:<p>Jmv 167 is an antagonist of the Cholecystokinin receptor.</p>Fórmula:C51H68N8O14SPureza:98%Cor e Forma:SolidPeso molecular:1049.21Des-Arg9-[Leu8]-Bradykinin acetate
CAS:<p>Des-Arg9-[Leu8]-Bradykinin acetate is a potent antagonist of the bradykinin receptor 1 (B1R), utilized in renal fibrosis research [1].</p>Fórmula:C43H67N11O12Pureza:98%Cor e Forma:SolidPeso molecular:930.06Arotinolol hydrochloride
CAS:<p>Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.</p>Fórmula:C15H22ClN3O2S3Pureza:99.84%Cor e Forma:SolidPeso molecular:408Lobeline sulfate
CAS:<p>Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.</p>Fórmula:C22H29NO6SPureza:98%Cor e Forma:White PowderPeso molecular:435.54Pafenolol
CAS:<p>Pafenolol is a P-glycoprotein modulator with a Ki value of 5.5 µM. pafenolol is an orally available and selective beta-adrenergic receptor antagonist.</p>Fórmula:C18H31N3O3Pureza:98.33%Cor e Forma:SolidPeso molecular:337.46S1R agonist 2
CAS:<p>S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.</p>Fórmula:C21H27NOPureza:98.85%Cor e Forma:SolidPeso molecular:309.45CAY10509
CAS:<p>CAY10509 is a PGF2α analogue and acts as an FP receptor inhibitor with an IC50 of 30 nM. It shows potential for use in studying the physiological regulatory mechanisms related to prostaglandins.</p>Fórmula:C23H35FO5SCor e Forma:SolidPeso molecular:442.586-Fluoro-N,N-diethyltryptamine
CAS:<p>6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.</p>Fórmula:C14H19FN2Cor e Forma:SolidPeso molecular:234.31Casopitant
CAS:<p>Casopitant (GW679769) is an orally active neurokinin-1 (NK1) receptor antagonist, researched for its potential use in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).</p>Fórmula:C30H35F7N4O2Cor e Forma:SolidPeso molecular:616.61Parstatin(mouse)
CAS:Peptide inhibits endothelial migration/proliferation (IC50 ~20μM), induces cell cycle arrest, triggers apoptosis, and has cardioprotective effects.Fórmula:C189H326N58O57S3Pureza:98%Cor e Forma:SolidPeso molecular:4419.19Kinetensin
CAS:Kinetensin is a neurotensin-like peptide.Fórmula:C56H85N17O11Pureza:98%Cor e Forma:White Lyophilised SolidPeso molecular:1172.38Amylin, amide, rat
CAS:<p>Amylin: peptide, 50% similar to CGRP, found with somatostatin in stomach cells, reduces acid secretion in mice.</p>Fórmula:C167H272N52O53S2Pureza:99.92%Cor e Forma:SolidPeso molecular:3920.448β-Hydroxy-exo-THC
CAS:<p>8β-Hydroxy-exo-THC, a cannabinoid ether analog, exhibits weak affinity for receptor sites with an IC50 of 1.2 μM.</p>Fórmula:C21H30O3Cor e Forma:SolidPeso molecular:330.46PEN (human)
CAS:<p>PEN (human) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.</p>Fórmula:C97H159N27O32Pureza:98%Cor e Forma:SolidPeso molecular:2215.492,6-DMA hydrochloride
CAS:<p>2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.</p>Fórmula:C11H18ClNO2Cor e Forma:SolidPeso molecular:231.72Parstatin(human)
CAS:Cell-permeable PAR1-derived peptide; inhibits endothelial migration, proliferation (IC50 ~3μM), induces apoptosis, and has cardioprotective effects.Fórmula:C191H330N64O53S3Pureza:98%Cor e Forma:SolidPeso molecular:4467.29Methylhexanamine hydrochloride
CAS:<p>Methylhexanamine hydrochloride is a fatty amine and vasoconstrictor that functions as a nasal decongestant when inhaled through the nasal mucosa.</p>Fórmula:C7H18ClNCor e Forma:SolidPeso molecular:151.688-Chloro caffeine
CAS:<p>8-Chloro caffeine binds to adenosine receptors with a Ki of 30 µM. It enhances UV-induced chromosomal aberrations in the Cl-I type Chinese hamster embryo lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine.</p>Fórmula:C8H9ClN4O2Cor e Forma:SolidPeso molecular:228.64UKH-1114
CAS:<p>UKH-1114 is a potent σ2 receptor/Tmem97 agonist with a Ki value of 46 nM, demonstrating antinociceptive effects against mechanical hypersensitivity. This compound alleviates mechanical hypersensitivity in mice caused by nerve injury without inducing motor impairment and is a promising candidate for neuropathic pain research.</p>Fórmula:C22H24F3NOCor e Forma:SolidPeso molecular:375.43sGC activator 2
<p>sGC activator 2 (Compound 16a) acts as an activator of soluble guanylate cyclase (sGC), enhancing the production of cGMP and exhibiting vasoprotective and anti-inflammatory properties.</p>Fórmula:C21H21FN8O3Cor e Forma:SolidPeso molecular:452.44QWF acetate
<p>QWF acetate is a Substance P antagonist peptide that specifically inhibits the binding to its receptor, NK1, and inhibits the activation of MRGPRX2.</p>Fórmula:C40H47N5O10Pureza:96.65%Cor e Forma:SolidPeso molecular:757.84Neuropeptide S(Rat)
CAS:<p>Potent endogenous neuropeptide S receptor (NSPR) agonist (EC50 = 3.2 nM).</p>Fórmula:C95H160N34O27Pureza:98%Cor e Forma:SolidPeso molecular:2210.52RFRP-3(human)
CAS:<p>NPFF1 receptor agonist, IC50 0.7 nM, blocks cAMP by forskolin. A GnIH homolog, it inhibits GnRH neuron activity.</p>Fórmula:C45H72N14O10Pureza:98%Cor e Forma:SolidPeso molecular:969.15Semaglutide TFA
<p>Semaglutide TFA is a glucagon-like peptide-1 congener that induces weight loss, lowers blood glucose levels and reduces cardiovascular risk in diabetic patients</p>Fórmula:C189H290F3N45O61Pureza:99.69%Cor e Forma:SolidPeso molecular:4225.6482APJ receptor agonist 1
CAS:<p>Potent APJ-R agonist 1, biphenyl acid, EC50: 0.093 nM (human), 0.12 nM (rat), targets apelin-13, promising for heart failure study.</p>Fórmula:C31H26ClN3O3Cor e Forma:SolidPeso molecular:524.02α-CGRP(human)
CAS:<p>Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.</p>Fórmula:C163H267N51O49S2Pureza:98%Cor e Forma:SolidPeso molecular:3789.33GLP-1 receptor agonist 9 citrate
<p>GLP-1 receptor agonist 9 citrate is an agonist of GLP-1.</p>Fórmula:C38H39ClFN3O12Pureza:98.76%Cor e Forma:SolidPeso molecular:784.18SR 142948 dihydrochloride
<p>SR 142948 dihydrochloride is a selective oral non-peptide NT antagonist, IC50 <4 nM, with brain penetration and potential for psychiatric research.</p>Fórmula:C39H53Cl2N5O6Cor e Forma:SolidPeso molecular:758.77MEN 11270
CAS:<p>B2 bradykinin receptor peptide antagonist, pKi 10.3; improves hypotension, bronchoconstriction; B2-selective over 29 receptors/ion channels.</p>Fórmula:C60H90N20O11SPureza:98%Cor e Forma:SolidPeso molecular:1299.56LY 293284
CAS:<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Fórmula:C19H26N2OCor e Forma:SolidPeso molecular:298.42Jatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Fórmula:C20H21NO5Cor e Forma:SolidPeso molecular:355.38
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