GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(1.025 produtos)
- Receptor de adenosina(249 produtos)
- Receptor adrenérgico(3.030 produtos)
- Receptor de Bombesina(35 produtos)
- Receptor de Bradicinina(61 produtos)
- CXCR(159 produtos)
- CaSR(34 produtos)
- Receptor de Canabinóides(217 produtos)
- Colecistocinina(1 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor Endotelina(86 produtos)
- Receptor GNRH(84 produtos)
- GPCR19(33 produtos)
- GRK(33 produtos)
- GTPase(22 produtos)
- Receptor Glucagon(196 produtos)
- Hedgehog/Smoothened(49 produtos)
- Receptor de Histamina(385 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(26 produtos)
- Receptor OX(42 produtos)
- Receptor opioide(325 produtos)
- PAFR(14 produtos)
- PKA(58 produtos)
- Receptor S1P(17 produtos)
- SGLT(31 produtos)
- Receptor Sigma(46 produtos)
Exibir 19 mais subcategorias
Foram encontrados 5982 produtos de "GPCR/Proteína-G"
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Calcitonin (salmon)
CAS:Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.Fórmula:C145H240N44O48S2Pureza:99.41% - 99.80%Cor e Forma:PowderPeso molecular:3431.85Cimetidine (Standard)
CAS:Cimetidine (Standard) is the standard substance of Cimetidine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cimetidine (SKF-92334) is a histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.Fórmula:C10H16N6SCor e Forma:Crystals Physical Description White Crystals With A Slight Sulfur-Mercaptan Odor (Ntp 1992)Peso molecular:252.34GLP-1R modulator C5
CAS:GLP-1R modulator C5 is a GLP-1R modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study of type II diabetes.Fórmula:C24H21NO3Pureza:99.59%Cor e Forma:SolidPeso molecular:371.43rac-Propranolol-d7
CAS:Rac-Propranolol-d7 is the deuterated form of Rac-Propranolol. Propranolol is a β-adrenergic receptor antagonist that inhibits β1AR.Fórmula:C16H14D7NO2Cor e Forma:SolidPeso molecular:266.39Allura Red AC (Standard)
CAS:Allura Red AC (Standard) is the standard substance of Allura Red AC, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Allura Red AC (CI 16035) is a very important food azo dye used in the food, pharmaceutical, paper, cosmetic and textile industries.Allura Red AC promotes susceptibility to experimental colitis via mouse intestinal serotonin.Fórmula:C18H14N2Na2O8S2Cor e Forma:Dark Maroon Solid PowderPeso molecular:496.42Tulobuterol-d9 HCl
CAS:Tulobuterol-d9 HCl is a deuterated compound of Tulobuterol HCl.Fórmula:C12H10D9Cl2NOCor e Forma:SolidPeso molecular:273.25Docosahexaenoic acid ethyl ester
CAS:Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) enhances 6-hydroxydopamine-induced neuronal damage by inducing lipid peroxidation in the mouse striatum, and can be used to study oxidative diseases of the retina or neurons.Fórmula:C24H36O2Pureza:98.35%Cor e Forma:SolidPeso molecular:356.54Levosalbutamol Hydrochloride
CAS:Levosalbutamol Hydrochloride is a β2-adrenergic receptor agonist. It is used to treat asthma and chronic obstructive pulmonary disease.Fórmula:C13H22ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:275.77Taranabant racemate
CAS:Taranabant racemate is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor.Fórmula:C27H25ClF3N3O2Pureza:98%Cor e Forma:SolidPeso molecular:515.95GLP-1R modulator C16
CAS:GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.Fórmula:C21H26ClFN2O3Pureza:99.6% - >99.99%Cor e Forma:SolidPeso molecular:408.89Asenapine hydrochloride
CAS:Asenapine hydrochloride (Org 5222 hydrochloride) is an antagonist of 5-hydroxytryptamine, adrenergic, dopamine, and histamine receptors with antipsychotic effects.Fórmula:C17H17Cl2NOCor e Forma:SolidPeso molecular:322.23Travoprost (Standard)
CAS:Travoprost (Standard) is the standard substance of Travoprost, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.Fórmula:C26H35F3O6Cor e Forma:Colorless OilPeso molecular:500.55Argipressin
CAS:Argipressin is a vasoconstrictive and antidiuretic hormone, binding to V1 receptors with Kd ~1.4 nM in rat heart and aortic cells.Fórmula:C46H65N15O12S2Pureza:98%Cor e Forma:White PowderPeso molecular:1084.23Furprofen
CAS:Furprofen, an NSAID, inhibits PGE synthesis, offers analgesic effects, and is orally taken for pain relief.Fórmula:C14H12O4Pureza:98.62% - 99.25%Cor e Forma:SolidPeso molecular:244.24GLP-1 receptor agonist 7
CAS:GLP-1 receptor agonist 7, potential for diabetes research, from patent WO2021219019A1.Fórmula:C31H30ClFN4O5Cor e Forma:SolidPeso molecular:593.05Lanreotide
CAS:Lanreotide, a somatostatin analogue, suppresses GH/IGF-I hypersecretion in acromegaly patients. It also used to manage neuroendocrine tumours.Fórmula:C54H69N11O10S2Cor e Forma:SolidPeso molecular:1096.32LUF5771
CAS:LUF5771: potent allosteric recLH & Org 43553 inhibitor, partial LH receptor activator with low efficacy.Fórmula:C24H23NO2Cor e Forma:SolidPeso molecular:357.44Clozapine-d8
CAS:Clozapine-d8 is a deuterium-labeled analog of Clozapine, used as an internal standard for mass spectrometric analysis of this atypical antipsychotic.Fórmula:C18H19ClN4Cor e Forma:SolidPeso molecular:334.87SLIGRL-NH2
CAS:SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a PAR-2 agonist that induces non-histaminergic pruritus.Fórmula:C29H56N10O7Pureza:98.29%Cor e Forma:SolidPeso molecular:656.82PD176252
CAS:PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.Fórmula:C32H36N6O5Pureza:99.00%Cor e Forma:SolidPeso molecular:584.67MRS-3777 hemioxalate
CAS:MRS-3777 hemioxalate, a selective adenosine A3 receptor antagonist, reverses the anti-injury perception effects of its corresponding agonist and serves as a valuable tool for studying inflammatory pain.
Fórmula:C17H19N5OC2H2O4Pureza:97.10%Cor e Forma:SolidPeso molecular:354.39Clothiapine
CAS:Clothiapine is an atypical antipsychotic of the dibenzothiazepine chemical class.Fórmula:C18H18ClN3SPureza:99.93%Cor e Forma:SolidPeso molecular:343.87MRGPRX4 modulator-2
CAS:MRGPRX4 modulator-2 (compound 1-55) is a highly potent antagonist of MRGPRX4 with an IC50 value of less than 100 nM. Its notable applications include research on autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson's Syndrome, and various chronic itch conditions [1].Fórmula:C15H9ClF4O3Pureza:99.24%Cor e Forma:SolidPeso molecular:348.68GRK2 Inhibitor
CAS:GRK2 Inhibitor is an inhibitor of β-Adrenergic Receptor Kinase 1 (β ARK1).Fórmula:C12H9NO6Cor e Forma:SolidPeso molecular:263.2Hydroxyzine dihydrochloride-d4
CAS:Hydroxyzine dihydrochloride-d4 is a deuterated compound of Hydroxyzine dihydrochloride.Fórmula:C21H25D4Cl3N2O2Cor e Forma:SolidPeso molecular:451.85Canagliflozin (Standard)
CAS:Canagliflozin (Standard) is the standard substance of Canagliflozin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM). Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM).Fórmula:C24H25FO5SCor e Forma:SolidPeso molecular:444.52Gizzerosine
CAS:Gizzerosine, a biogenic amine formed during feed processing, is a toxicant that induces mortality in livestock.Fórmula:C11H20N4O2Cor e Forma:SolidPeso molecular:240.33-Hydroxy agomelatine D3
CAS:3-Hydroxy agomelatine D3 is a deuterated metabolite of Agomelatine and a 5-HT2C antagonist (IC50: 3.2 μM, Ki: 1.8 μM).Fórmula:C15H17NO3Pureza:98%Cor e Forma:SolidPeso molecular:262.32TP-16
CAS:TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.
Fórmula:C24H22FNO4SPureza:98.53% - 99.15%Cor e Forma:SolidPeso molecular:439.5V-0219
CAS:V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.Fórmula:C20H25F3N4O2Pureza:99.91%Cor e Forma:SoildPeso molecular:410.43Spiroxatrine
CAS:Spiroxatrine (R 5188) is a 5-HT1α and α2-adrenergic dual antagonist with sedative activity for the study of diseases related to the cardiovascular system.Fórmula:C22H25N3O3Pureza:99.94%Cor e Forma:SolidPeso molecular:379.45Fedovapagon
CAS:Fedovapagon (VA106483) is a pressin V2 receptor (V2R) agonist for the study of overactive bladder syndrome.Fórmula:C27H34N4O3Pureza:99.46%Cor e Forma:SolidPeso molecular:462.58Setiptiline maleate
CAS:Setiptiline maleate is a norepinephrine reuptake inhibitor, 2-adrenergic receptor antagonist, H1 receptor inverse agonist, 5-HT serotonin receptor antagonist.Fórmula:C23H23NO4Pureza:99.94%Cor e Forma:SolidPeso molecular:377.43LY223982
CAS:LY223982 is an effective and specific inhibitor of the leukotriene B4 receptor (IC50: 13.2 nM). It also can against [3H]LTB4 binding to LTB4 receptor.Fórmula:C30H30O7Pureza:99.86%Cor e Forma:SolidPeso molecular:502.56Trimethobenzamide
CAS:Trimethobenzamide (Ro 2-9578) is a D2 antagonist used to prevent nausea and vomiting.Fórmula:C21H28N2O5Cor e Forma:SolidPeso molecular:388.46Thiethylperazine
CAS:Thiethylperazine (Tietilperazina) is a D2 receptor and H1 receptor antagonist, and an ABCC1 activator with antimicrobial and antiemetic activity.Fórmula:C22H29N3S2Pureza:98.72%Cor e Forma:SolidPeso molecular:399.62SB-408124 Hydrochloride
CAS:SB-408124 Hydrochloride is a non-peptide OX1 receptor antagonist(Ki of 57 nM and 27 nM in both whole cell and membrane, respectively).Fórmula:C19H19ClF2N4OPureza:98%Cor e Forma:SolidPeso molecular:392.83Levomepromazine
CAS:Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.Fórmula:C19H24N2OSPureza:99.15%Cor e Forma:SolidPeso molecular:328.47L 888607
CAS:L 888607 is an effective and selective CRTH2 agonist (Ki: 0.8 nM).Fórmula:C19H15ClFNO2SCor e Forma:SolidPeso molecular:375.84ML 00253764
CAS:melanocortin MC4 receptor antagonistFórmula:C18H18BrFN2OCor e Forma:SolidPeso molecular:377.25(S)-(+)-Dimethindene maleate
CAS:(S)-(+)-Dimethindene maleate is an orally available, selective muscarinic M2 receptor and histamine H1 receptor antagonist that inhibits muscarinic M1 receptorsFórmula:C24H28N2O4Pureza:99.94%Cor e Forma:SolidPeso molecular:408.49SANT 2
CAS:SANT 2 is a Hedgehog (Hh) signaling pathway antagonist with potential anti-inflammatory and anti-cancer activities.Fórmula:C26H26ClN3O4Pureza:99.23%Cor e Forma:SolidPeso molecular:479.96Ziprasidone D8
CAS:Ziprasidone D8, deuterium-labeled, is a potent antipsychotic, antagonizing 5-HT and dopamine receptors.Fórmula:C21H21ClN4OSPureza:98%Cor e Forma:SolidPeso molecular:420.99Olanzapine D3
CAS:Olanzapine D3 is the deuterium labeled Olanzapine.Fórmula:C17H20N4SPureza:98%Cor e Forma:SolidPeso molecular:315.45Cimbuterol-d9
CAS:Cimbuterol-d9 is a deuterated compound of Cimbuterol.Fórmula:C13H10D9N3OPureza:99.22%Cor e Forma:SolidPeso molecular:242.37Zilpaterol-d7
CAS:Zilpaterol-d7 (trans-(±)-Zilpaterol-d7) is a deuterium-labeled version of Zilpaterol, a β-adrenergic receptor agonist.Fórmula:C14H12D7N3O2Cor e Forma:SolidPeso molecular:268.36Cariprazine D6
CAS:Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).
Fórmula:C21H26D6Cl2N4OPureza:98%Cor e Forma:SolidPeso molecular:433.45Calcium-Sensing Receptor Antagonists I
CAS:Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.Fórmula:C23H24N2O2Cor e Forma:SolidPeso molecular:360.45Ivabradine-d6 hydrochloride
CAS:Ivabradine HCl: novel If inhibitor, IC50 2.9 μM; lowers heart rate. Ivabradine D6 HCl is its deuterium variant.Fórmula:C27H37ClN2O5Pureza:98%Cor e Forma:SolidPeso molecular:511.08(+)-Penbutolol
CAS:(+)-Penbutolol is an antagonist of β-adrenoceptor(IC50 of 0.74 μM). (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action.Fórmula:C18H29NO2Cor e Forma:SolidPeso molecular:291.43
