GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(1.024 produtos)
- Receptor de adenosina(249 produtos)
- Receptor adrenérgico(3.030 produtos)
- Receptor de Bombesina(35 produtos)
- Receptor de Bradicinina(61 produtos)
- CXCR(159 produtos)
- CaSR(34 produtos)
- Receptor de Canabinóides(217 produtos)
- Colecistocinina(1 produtos)
- Receptor de Dopamina(443 produtos)
- Receptor Endotelina(86 produtos)
- Receptor GNRH(84 produtos)
- GPCR19(33 produtos)
- GRK(33 produtos)
- GTPase(22 produtos)
- Receptor Glucagon(196 produtos)
- Hedgehog/Smoothened(49 produtos)
- Receptor de Histamina(385 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(26 produtos)
- Receptor OX(42 produtos)
- Receptor opioide(326 produtos)
- PAFR(14 produtos)
- PKA(54 produtos)
- Receptor S1P(17 produtos)
- SGLT(31 produtos)
- Receptor Sigma(46 produtos)
Exibir 19 mais subcategorias
Foram encontrados 5981 produtos de "GPCR/Proteína-G"
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Levomepromazine
CAS:Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.Fórmula:C19H24N2OSPureza:99.15%Cor e Forma:SolidPeso molecular:328.47Clencyclohexerol-d10
CAS:Argipressin inhibits central corticotropin-releasing hormone. Argipressin acts as an inhibitory factor in the regulation of central CRH levels.Fórmula:C14H20Cl2N2O2Cor e Forma:SolidPeso molecular:329.29Nefazodone
CAS:Nefazodone (Nefadar) is an oral antidepressant that is an antagonist of postsynaptic 5-HT 2A receptors and 5-HT 2C receptors, and SNDRI.Fórmula:C25H32ClN5O2Pureza:99.85%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:470.01Ref: TM-T21451
2mg45,00€5mg64,00€10mg91,00€25mg187,00€50mg291,00€100mg446,00€200mg637,00€1mL*10mM (DMSO)100,00€MRGPRX4 modulator-2
CAS:MRGPRX4 modulator-2 (compound 1-55) is a highly potent antagonist of MRGPRX4 with an IC50 value of less than 100 nM. Its notable applications include research on autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson's Syndrome, and various chronic itch conditions [1].Fórmula:C15H9ClF4O3Pureza:99.24%Cor e Forma:SolidPeso molecular:348.68Dapagliflozin impurity
CAS:Dapagliflozin impurity is the enantiomer of Dapagliflozin, Dapagliflozin is a sodium glucose transporter 2 inhibitor.Fórmula:C21H25ClO7Cor e Forma:SolidPeso molecular:424.87Taranabant racemate
CAS:Taranabant racemate is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor.Fórmula:C27H25ClF3N3O2Pureza:98%Cor e Forma:SolidPeso molecular:515.95MRS-3777 hemioxalate
CAS:<p>MRS-3777 hemioxalate, a selective adenosine A3 receptor antagonist, reverses the anti-injury perception effects of its corresponding agonist and serves as a valuable tool for studying inflammatory pain.</p>Fórmula:C17H19N5OC2H2O4Pureza:97.10%Cor e Forma:SolidPeso molecular:354.39GLP-1R modulator C5
CAS:GLP-1R modulator C5 is a GLP-1R modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study of type II diabetes.Fórmula:C24H21NO3Pureza:99.59%Cor e Forma:SolidPeso molecular:371.43BW 723C86
CAS:BW 723C86 is a 5-HT2B receptor agonist with anxiolytic effects, inducing overeating and reduced grooming in rats, useful in studying neurological disorders.Fórmula:C16H19ClN2OSPureza:99.35%Cor e Forma:SolidPeso molecular:322.85Revdofilimab
CAS:Revdofilimab (ABBV-368) is a human IgG1 monoclonal antibody targeting OX40, a receptor on certain T cells.Pureza:98.80% - 98.80%Cor e Forma:LiquidPeso molecular:145.60 kDaTFLLR-NH2(TFA)
CAS:TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM. EC50: 1.9 μM (PAR1)Fórmula:C33H54F3N9O8Pureza:98%Cor e Forma:SolidPeso molecular:761.83SLIGRL-NH2
CAS:SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a PAR-2 agonist that induces non-histaminergic pruritus.Fórmula:C29H56N10O7Pureza:98.29%Cor e Forma:SolidPeso molecular:656.82PSB-0739
CAS:PSB-0739 Selective platelet P2Y12 receptor antagonist characterized by competitive binding with antithrombotic and platelet aggregation modulating effects.Fórmula:C26H17N3Na2O8S2Pureza:98%Cor e Forma:SolidPeso molecular:609.54Calcium-Sensing Receptor Antagonists I
CAS:Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.Fórmula:C23H24N2O2Cor e Forma:SolidPeso molecular:360.45WAY-100635
CAS:WAY-100635 is a potent 5-HT 1A receptor antagonist pyramidal neuron firing frequency during conditioned reflexes; a dopamine D4 receptor agonist .Fórmula:C25H34N4O2Pureza:98.972%Cor e Forma:SolidPeso molecular:422.56TP-16
CAS:<p>TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.</p>Fórmula:C24H22FNO4SPureza:98.53% - 99.15%Cor e Forma:SolidPeso molecular:439.5Etofylline clofibrate
CAS:Etofylline clofibrate has a hypolipidemic and antithrombotic effect and it also has an agonistic interaction with intimal PGI2.Fórmula:C19H21ClN4O5Cor e Forma:SolidPeso molecular:420.85LUF5771
CAS:LUF5771: potent allosteric recLH & Org 43553 inhibitor, partial LH receptor activator with low efficacy.Fórmula:C24H23NO2Cor e Forma:SolidPeso molecular:357.44SKF-82958 hydrobromide
CAS:SKF-82958 hydrobromide is a D1/D5 receptor full agonist.Fórmula:C19H21BrClNO2Pureza:98%Cor e Forma:SolidPeso molecular:410.73Fenoterol-d6 Hydrobromide
CAS:Fenoterol-d6 Hydrobromide is a deuterated compound of Fenoterol Hydrobromide. Fenoterol Hydrobromide has a CAS number of 1944-12-3. Fenoterol hydrobromide, the hydrobromide salt of fenoterol, is a β2 adrenoreceptor agonist with bronchodilator activity.Fórmula:C17H16D6BrNO4Peso molecular:390.30Sulfisoxazole (Standard)
CAS:Sulfisoxazole (Standard) is the standard substance of Sulfisoxazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sulfisoxazole (Sulfafurazole) is a short-acting sulfonamide antibacterial with activity against a wide range of gram-negative and gram-positive organisms.Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A.Fórmula:C11H13N3O3SPeso molecular:267.30Fipexide hydrochloride
CAS:Fipexide (hydrochloride) is a kind of psychoactive drug of the piperazine class.Fórmula:C20H22Cl2N2O4Cor e Forma:SolidPeso molecular:425.31Gizzerosine
CAS:Gizzerosine, a biogenic amine formed during feed processing, is a toxicant that induces mortality in livestock.Fórmula:C11H20N4O2Cor e Forma:SolidPeso molecular:240.3SUN B8155
CAS:SUN B8155 is a CT receptor agonist that induces cAMP formation in cells expressing recombinant human CT receptor.Fórmula:C14H15N3O3Pureza:99.38% - 99.38%Cor e Forma:SolidPeso molecular:273.29Travoprost (Standard)
CAS:Travoprost (Standard) is the standard substance of Travoprost, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.Fórmula:C26H35F3O6Peso molecular:500.553-O-Methyldopa-d3
CAS:3-O-Methyldopa-d3 is a deuterated compound of 3-O-Methyldopa. 3-O-Methyldopa has a CAS number of 300-48-1.Fórmula:C10H10D3NO4Peso molecular:214.23Lecirelin
CAS:Lecirelin is a synthetic GnRH (gonadotropin releasing hormone) analogue which shows a great efficacy in the treatment of bovine ovarian follicular cysts.Fórmula:C59H84N16O12Cor e Forma:SolidPeso molecular:1209.4Flibanserin-d4
CAS:Flibanserin: Serotonin 5-HT1A agonist (Ki=1 nM), 5-HT2A antagonist (49 nM). Flibanserin D4 is deuterium-labeled.Fórmula:C20H21F3N4OPureza:98%Cor e Forma:SolidPeso molecular:394.43Hydroxyzine dihydrochloride-d4
CAS:Hydroxyzine dihydrochloride-d4 is a deuterated compound of Hydroxyzine dihydrochloride.Fórmula:C21H25D4Cl3N2O2Cor e Forma:SolidPeso molecular:451.85Cimetidine (Standard)
CAS:Cimetidine (Standard) is the standard substance of Cimetidine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cimetidine (SKF-92334) is a histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.Fórmula:C10H16N6SPeso molecular:252.341-Methyl-4-imidazoleacetic Acid (hydrochloride)
CAS:MIMA, a stable histamine byproduct from N-methylhistamine oxidation, indicates systemic mastocytosis via urinary levels.Fórmula:C6H9ClN2O2Cor e Forma:SolidPeso molecular:176.601Clothiapine
CAS:Clothiapine is an atypical antipsychotic of the dibenzothiazepine chemical class.Fórmula:C18H18ClN3SPureza:99.93%Cor e Forma:SolidPeso molecular:343.87Endothelin-3 (Rat,Human) (TFA)
Endothelin-3 (Rat, Human) (TFA) is a 21-amino acid vasoactive peptide of endothelial origi, an agonist for the endothelin receptor type B (EDNRB).Fórmula:C123H169F3N26O35S4·xC2HF3O2Pureza:98%Cor e Forma:SolidPeso molecular:2757.07 (free base)Allura Red AC (Standard)
CAS:Allura Red AC (Standard) is the standard substance of Allura Red AC, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Allura Red AC (CI 16035) is a very important food azo dye used in the food, pharmaceutical, paper, cosmetic and textile industries.Allura Red AC promotes susceptibility to experimental colitis via mouse intestinal serotonin.Fórmula:C18H14N2Na2O8S2Cor e Forma:Dark Maroon Solid PowderPeso molecular:496.42Asenapine
CAS:Asenapine (Org 5222) is a 5-HT receptor, adrenergic receptor, and histamine receptor antagonist with antipsychotic properties for the treatment of schizophreniaFórmula:C17H16ClNOPureza:99.64%Cor e Forma:CoaPeso molecular:285.77Agomelatine (L(+)-Tartaric acid)
CAS:Agomelatine (L(+)-Tartaric acid) is an MT1/MT2 agonist and selective 5-HT2C antagonist, supporting melatonergic and serotonergic signaling studies in neuroscience.Fórmula:C19H23NO8Pureza:99.79%Cor e Forma:SolidPeso molecular:393.39GRK2 Inhibitor
CAS:GRK2 Inhibitor is an inhibitor of β-Adrenergic Receptor Kinase 1 (β ARK1).Fórmula:C12H9NO6Cor e Forma:SolidPeso molecular:263.2(Rac)-Rotigotine hydrochloride
CAS:(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.Fórmula:C19H26ClNOSCor e Forma:SolidPeso molecular:351.93Neurotensin(8-13)
CAS:Neurotensin(8-13) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.Fórmula:C38H64N12O8Pureza:99.95%Cor e Forma:SolidPeso molecular:816.99GR79236
CAS:GR79236 is an effective and selective adenosine A1 receptor agonist (Ki: 3.1 nM) that has analgesic and anti-inflammatory actions.Fórmula:C15H21N5O5Cor e Forma:SolidPeso molecular:351.36Pramipexole dihydrochloride
CAS:Pramipexole dihydrochloride could be used to treat Parkinson disease.Fórmula:C10H18ClN3SPureza:98%Cor e Forma:White Crystalline PowderPeso molecular:247.79LAS101057
CAS:LAS101057 is a novel orally available and potent and selective A2B receptor antagonist for the study of asthma.Fórmula:C18H14FN5OPureza:99.03% - >99.99%Cor e Forma:SolidPeso molecular:335.34Omidenepag
CAS:Omidenepag (UR-7276) is an EP2 agonist and a novel topical ocular hypotensive agent.Omidenepag can be used to study glaucoma and hypertension.Fórmula:C23H22N6O4SPureza:99.67% - 99.77%Cor e Forma:SolidPeso molecular:478.523-Hydroxy agomelatine
CAS:3-Hydroxy agomelatine (3-Hydroxyagomelatine) is a 5-HT2C receptor antagonist used in the study of neurological disorders.Fórmula:C15H17NO3Cor e Forma:SolidPeso molecular:259.3V-0219
CAS:V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.Fórmula:C20H25F3N4O2Pureza:99.91%Cor e Forma:SoildPeso molecular:410.43SB-200646A
CAS:SB-200646A: oral 5-HT2B/2C antagonist; higher affinity than 5-HT2A (pKi: 7.5, 6.9 vs 5.2); anxiolytic with in vivo effects.Fórmula:C15H15ClN4OPureza:98%Cor e Forma:SolidPeso molecular:302.76PD176252
CAS:PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.Fórmula:C32H36N6O5Pureza:99.00%Cor e Forma:SolidPeso molecular:584.67Olanzapine D3
CAS:Olanzapine D3 is the deuterium labeled Olanzapine.Fórmula:C17H20N4SPureza:98%Cor e Forma:SolidPeso molecular:315.45Ziprasidone D8
CAS:Ziprasidone D8, deuterium-labeled, is a potent antipsychotic, antagonizing 5-HT and dopamine receptors.Fórmula:C21H21ClN4OSPureza:98%Cor e Forma:SolidPeso molecular:420.99GLP-1 receptor agonist 2
CAS:GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor (GLP-1R) agonist.Fórmula:C30H31ClFN5O4Cor e Forma:SolidPeso molecular:580.05
