GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.949 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5378 produtos de "GPCR/Proteína-G"
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Ibutamoren
CAS:<p>Ibutamoren (MK-677) is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It also alters the metabolism of body fat and so may have an application in the treatment of obesity.</p>Fórmula:C27H36N4O5SPureza:97.59%Cor e Forma:SolidPeso molecular:528.66GBR 12935
CAS:<p>GBR-12935: selective dopamine inhibitor, used in Parkinson's research.</p>Fórmula:C28H34N2OCor e Forma:SolidPeso molecular:414.58M 1145 acetate
<p>M1145 acetate: chimeric peptide, selective GAL2 agonist, Ki=6.55 nM; >90x affinity vs GAL1, 76x vs GalR3. Enhances galanin signal.</p>Fórmula:C130H209N37O34Pureza:99.1%Cor e Forma:SolidPeso molecular:2834.28Loxapine hydrochloride
CAS:<p>Loxapine hydrochloride, an oral anti-psychotic, inhibits dopamine and blocks 5-HT receptors.</p>Fórmula:C18H19Cl2N3OCor e Forma:SolidPeso molecular:364.27Brompheniramine
CAS:<p>Brompheniramine, an alkylamine antihistamine, targets H1 receptors (Kd=6.06nM) and has anticholinergic/depressant qualities. Blocks Ca/Na/hERG channels.</p>Fórmula:C16H19BrN2Cor e Forma:SolidPeso molecular:319.24GSK 789472 hydrochloride
CAS:GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.Fórmula:C15H22ClN3OPureza:99.89%Cor e Forma:SolidPeso molecular:295.81Neuropeptide EI, rat acetate
Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.Fórmula:C65H102N16O25Pureza:95.55%Cor e Forma:SolidPeso molecular:1507.6CYM 50358 hydrochloride (1314212-39-9 free base)
CAS:CYM50358 HCl is an S1P4 antagonist.Fórmula:C20H19Cl3N2O2Pureza:99.57%Cor e Forma:SolidPeso molecular:425.73N-ACETYLTRYPTAMINE
CAS:<p>N-ACETYLTRYPTAMINE is a partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.</p>Fórmula:C12H14N2OPureza:98.79%Cor e Forma:PowderPeso molecular:202.25GR 125743
CAS:GR 125743 is a novel antagonist of 5-HT1B/1D receptor.Fórmula:C25H28N4O2Pureza:99.76%Cor e Forma:SolidPeso molecular:416.52Enavogliflozin
CAS:<p>Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.</p>Fórmula:C24H27ClO6Pureza:97.37%Cor e Forma:SolidPeso molecular:446.92Intepirdine
CAS:<p>Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer's Disease.</p>Fórmula:C19H19N3O2SPureza:98% - 98.63%Cor e Forma:SolidPeso molecular:353.44ETHYL 2-AMINO-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE
CAS:<p>ETHYL 2-AMINO-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE targets the prostaglandin E2 receptor EP2 subtype (human)</p>Fórmula:C14H15NO2SPureza:99.98%Cor e Forma:SolidPeso molecular:261.34Olodaterol hydrochloride
CAS:<p>Olodaterol hydrochloride (BI-1744 HCl) is a novel, long-acting β2-adrenergic agonist that exerts its pharmacological effect by binding and activating β2-AR.</p>Fórmula:C21H27ClN2O5Pureza:99.11%Cor e Forma:SolidPeso molecular:422.9Mosapride Citrate
CAS:<p>Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.</p>Fórmula:C21H25ClFN3O3·C6H8O7Pureza:99.70%Cor e Forma:White PowderPeso molecular:614.02Blarcamesine
CAS:<p>Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.</p>Fórmula:C19H23NOPureza:99.87%Cor e Forma:SolidPeso molecular:281.39Nomifensine maleate
CAS:<p>Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder.</p>Fórmula:C20H22N2O4Pureza:98.46%Cor e Forma:SolidPeso molecular:354.4Mecamylamine hydrochloride
CAS:<p>Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension.</p>Fórmula:C11H22ClNPureza:99.76% - >99.99%Cor e Forma:White SolidPeso molecular:203.75Buserelin Acetate (57982-77-1 free base)
CAS:<p>Buserelin Acetate (57982-77-1 free base) (Buserelin Acetate) is an agonist of gonadotropin-releasing hormone receptor(GnRHR).</p>Fórmula:C62H90N16O15Pureza:99.31% - 99.78%Cor e Forma:SolidPeso molecular:1299.48SB 242084 dihydrochloride
CAS:SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.Fórmula:C21H21Cl3N4O2Cor e Forma:SolidPeso molecular:467.781-(1-Naphthyl) piperazine hydrochloride
CAS:<p>1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple</p>Fórmula:C14H17ClN2Pureza:98.27%Cor e Forma:SolidPeso molecular:248.75HAEGTFTSDVSSYLE
<p>HAEGTFTSDVSSYLE is a peptide. GLP-I analog contains the sequence.</p>Fórmula:C71H103N17O28Pureza:>99.99%Cor e Forma:SolidPeso molecular:1642.71Alimemazine hemitartrate
CAS:<p>Alimemazine hemitartrate (Trimeprazine hemitartrate) is aphenothiazine derivative that is used as an antipruritic.</p>Fórmula:C18H22N2SC4H6O6Pureza:98.16% - 99.69%Cor e Forma:SolidPeso molecular:448.53CCR2 antagonist 4 hydrochloride
CAS:CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).Fórmula:C21H22Cl2F3N3O2Cor e Forma:SolidPeso molecular:476.32CAY10444
CAS:<p>CAY10444 is an S1P3 specific antagonist.</p>Fórmula:C15H29NO2SPureza:99.15% - 99.61%Cor e Forma:SolidPeso molecular:287.46CYM-5520
CAS:<p>CYM-5520 is a noncompetitive allosteric agonist of S1P2</p>Fórmula:C21H19N3O2Pureza:99.47%Cor e Forma:SolidPeso molecular:345.39ML 10302
CAS:<p>ML 10302 is a potent 5-HT4 agonist with Ki of 1.07 nM, boosts bowel movement, and may aid in neurology research.</p>Fórmula:C15H21ClN2O3Cor e Forma:SolidPeso molecular:312.79N-Cbz-DL-tryptophan
CAS:<p>N-Cbz-DL-tryptophan is a cholecystokinin receptor antagonist, abolished the response of the isolated heart to CCK-8.</p>Fórmula:C19H18N2O4Pureza:99.97%Cor e Forma:SolidPeso molecular:338.36Samelisant dihydrochloride
CAS:<p>SUVN-G3031: H3 receptor antagonist; may treat cognitive issues, ADHD, epilepsy, sleep, obesity, schizophrenia, eating disorders, pain.</p>Fórmula:C21H33Cl2N3O3Cor e Forma:SolidPeso molecular:446.41Galnon TFA
CAS:<p>Galnon is a novel non-peptide galanin receptor agonist (GAL1 and GAL2 with Ki of 11.7 and 34.1 μM respectively).</p>Fórmula:C42H47F3N4O8Pureza:99.47%Cor e Forma:SolidPeso molecular:792.84CRT0273750
CAS:<p>CRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an autotaxin (ATX) inhibitor with IC50 of 0.014 μM.</p>Fórmula:C25H22ClF3N4O2Pureza:99.91%Cor e Forma:SolidPeso molecular:502.92Picotamide
CAS:<p>Picotamide has anticoagulant and fibrinolytic properties.</p>Fórmula:C21H20N4O3Pureza:98.90%Cor e Forma:SolidPeso molecular:376.41Bevantolol
CAS:<p>Bevantolol, a selective β-1 adrenoceptor antagonist, is utilized for the investigation of angina pectoris and hypertension [1].</p>Fórmula:C20H27NO4Cor e Forma:SolidPeso molecular:345.43Lodoxamide
CAS:<p>Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis.</p>Fórmula:C11H6ClN3O6Pureza:99.13% - 99.81%Cor e Forma:SolidPeso molecular:311.63Benorilate
CAS:<p>Benorilate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.</p>Fórmula:C17H15NO5Pureza:98.39% - 99.85%Cor e Forma:SolidPeso molecular:313.3NPS ALX Compound 4a
CAS:NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)Fórmula:C25H25N3O2SPureza:98%Cor e Forma:SolidPeso molecular:431.55Carbazochrome
CAS:<p>Carbazochrome (Adchnon) is an antihemorrhagic that promotes platelet aggregation to stop bleeding, possibly for surgeries and hemorrhoids treatment.</p>Fórmula:C10H12N4O3Pureza:98.36%Cor e Forma:Nacarat Crystalline PowderPeso molecular:236.23Quipazine maleate
CAS:<p>Quipazine maleate is a 5-HT agonist affecting L-02 hepatocytes and raphe neurons, causing smooth muscle contracture and bronchospasm.</p>Fórmula:C17H19N3O4Cor e Forma:SolidPeso molecular:329.36Olcegepant
CAS:<p>Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4</p>Fórmula:C38H47Br2N9O5Pureza:96.08% - 97.24%Cor e Forma:SolidPeso molecular:869.65Sigma-LIGAND-1 hydrochloride
CAS:<p>Sigma-LIGAND-1 HCl: selective sigma receptor ligand; DTG IC50: 16 nM, PPP IC50: 19 nM; weak D2 receptor affinity, Ki: 4000 nM.</p>Fórmula:C27H34ClNO4Cor e Forma:SolidPeso molecular:472.02Volinanserin
CAS:Volinanserin (MDL100907) is a potent 5-HT2 receptor antagonist with a Ki of 0.36 nM, 300x selective over 5-HT1c, alpha-1, and sigma receptors.Fórmula:C22H28FNO3Pureza:98.94% - 99.95%Cor e Forma:SolidPeso molecular:373.46Enprofylline
CAS:<p>Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor.</p>Fórmula:C8H10N4O2Pureza:98.37%Cor e Forma:SolidPeso molecular:194.19Niaprazine
CAS:<p>Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.</p>Fórmula:C20H25FN4OPureza:99.56%Cor e Forma:SolidPeso molecular:356.44Rimcazole dihydrochloride
CAS:<p>Rimcazole dihydrochloride: a σ receptor antagonist, hydrochloride salt, blocks dopamine uptake.</p>Fórmula:C21H28ClN3Pureza:99.63%Cor e Forma:SolidPeso molecular:357.92γ-L-Glutamyl-L-alanine
CAS:<p>γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is the substrate of CRF21 (gamma-Glutamylcyclotransferase, GGCT).</p>Fórmula:C8H14N2O5Pureza:99.49%Cor e Forma:SolidPeso molecular:218.21Tavapadon
CAS:<p>Tavapadon (CVL-751) is an orally active and highly selective dopamine D1/D5 receptor partial agonist.</p>Fórmula:C19H16F3N3O3Pureza:99.33% - 99.8%Cor e Forma:SolidPeso molecular:391.34Piboserod hydrochloride
CAS:<p>Piboserod HCl is a selective antagonist of 5-HT4 and muscarinic receptor.</p>Fórmula:C22H32ClN3O2Cor e Forma:SolidPeso molecular:405.96YIL781 hydrochloride
CAS:<p>YIL781 is a ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM) with no significant affinity for the motilin receptor (Ki = 6 μM).</p>Fórmula:C24H29ClFN3O2Cor e Forma:SolidPeso molecular:445.96Cyclopiazonic acid
CAS:<p>Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A.</p>Fórmula:C20H20N2O3Pureza:99.27% - 99.80%Cor e Forma:SolidPeso molecular:336.38SB756050
CAS:<p>SB756050 is a specific TGR5 agonist.</p>Fórmula:C21H28N2O8S2Pureza:98.78% - >99.99%Cor e Forma:SolidPeso molecular:500.59
