GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.949 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5378 produtos de "GPCR/Proteína-G"
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ML-193
CAS:ML-193: GPR55 antagonist, IC50 221nM, 27x selective over GPR35/CB1/CB2, may aid Parkinson's symptoms.Fórmula:C28H25N5O4SPureza:97.74%Cor e Forma:SolidPeso molecular:527.59Dolasetron Mesylate hydrate
CAS:<p>Dolasetron Mesylate hydrate blocks 5HT3 to prevent chemo and radiotherapy nausea.</p>Fórmula:C20H26N2O7SPureza:99.86% - 99.9%Cor e Forma:SolidPeso molecular:438.49BMY-25368
CAS:<p>BMY-25368 is a long-acting antagonist of the H2-receptor.</p>Fórmula:C19H25N3O3Cor e Forma:SolidPeso molecular:343.42Fertirelin
CAS:<p>Fertirelin, or fertirelin acetate, sold under the brand name Ovalyse, is a gonadotropin-releasing hormone agonist (GnRH agonist).</p>Fórmula:C55H76N16O12Pureza:>99.99%Cor e Forma:SolidPeso molecular:1153.29Bretylium tosylate
CAS:<p>Bretylium tosylate is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters, a available antiarrhythmic drug for ventricular arrhythmias.</p>Fórmula:C18H24BrNO3SPureza:>99.99%Cor e Forma:SolidPeso molecular:414.36Guanethidine monosulfate
CAS:<p>Guanethidine sulfate is an antihypertensive drug that reduces the release of catecholamines.</p>Fórmula:C10H24N4O4SPureza:99.61% - 99.74%Cor e Forma:SolidPeso molecular:296.39SAX-187 hydrochloride
CAS:<p>WAY-181187 is a potent, selective 5-HT6 agonist with high affinity (2.2-4.8 nM), and increases GABA in rat cortex at 3-30 mg/kg s.c.</p>Fórmula:C15H14Cl2N4O2S2Cor e Forma:SolidPeso molecular:417.33Seltorexant hydrochloride
CAS:<p>Seltorexant hydrochloride is a selective, orally active and high-affinity antagonist of OX2R with pKi values of 8.0 and 8.1 for human and rat OX2R.</p>Fórmula:C21H23ClFN7OPureza:98%Cor e Forma:SolidPeso molecular:443.91Ritanserin
CAS:<p>Ritanserin (R 55667) is a long-acting, highly potent, relatively selective, orally bioavailable 5-HT2 receptor antagonist.Cost-effective and quality-assured.</p>Fórmula:C27H25F2N3OSPureza:99.77% - 99.89%Cor e Forma:SolidPeso molecular:477.57MK 571
CAS:<p>MK 571 (L660711) is an orally active antagonist of CysLT1 receptor.</p>Fórmula:C26H27ClN2O3S2Pureza:98.69% - 99.65%Cor e Forma:SolidPeso molecular:515.09Mecamylamine
CAS:<p>Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.</p>Fórmula:C11H21NCor e Forma:SolidPeso molecular:167.29Trimethobenzamide hydrochloride
CAS:<p>Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.</p>Fórmula:C21H29ClN2O5Pureza:99.52%Cor e Forma:SolidPeso molecular:424.92CRF (6-33) acetate(120066-38-8 free base)
<p>CRFBP inhibitor peptide; reduces weight gain, boosts activity in obese rats.</p>Fórmula:C143H235N41O45SPureza:97.12%Cor e Forma:SolidPeso molecular:3280.76TNCA
CAS:<p>TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.</p>Fórmula:C12H12N2O2Pureza:97.33% - 97.73%Cor e Forma:SolidPeso molecular:216.24Clobenpropit 2HBr
CAS:<p>Clobenpropit 2HBr is a histamine H3 receptor antagonist. It has neuroprotective effects via stimulation of GABA release in the brain.</p>Fórmula:C14H17ClN4SCor e Forma:SolidPeso molecular:308.83L-DOPA methyl ester (hydrochloride)
CAS:<p>L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.</p>Fórmula:C10H14ClNO4Pureza:98.69% - 99.81%Cor e Forma:White SolidPeso molecular:247.675Pipamperone HCl
CAS:<p>Pipamperone blocks 5-HT2A/B/C, D2/D3/D4, α1/α2 receptors; favors 5-HT2A/D4 over D2; negligible affinity for H1, mACh. Highly selective at low doses.</p>Fórmula:C21H31ClFN3O2Cor e Forma:SolidPeso molecular:411.95Phentolamine
CAS:<p>Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist</p>Fórmula:C17H19N3OPureza:99.86% - 99.94%Cor e Forma:Crystals SolidPeso molecular:281.35Fluparoxan HCl
CAS:<p>Fluparoxan is a potent α2-adrenergic receptor antagonist (pKB = 7.9) with excellent α2/α1 selectivity (2630 fold).</p>Fórmula:C10H11ClFNO2Cor e Forma:SolidPeso molecular:231.65Vilanterol trifenatate
CAS:<p>Vilanterol trifenatate is a long-acting agonist of β2-adrenoceptor (β2-AR) with inherent 24-hour activity(β2-AR, β1-AR and β3-AR pEC50s of 10.37, 6.98 and 7.36, respectively)</p>Fórmula:C44H49Cl2NO7Pureza:99.51% - >99.99%Cor e Forma:SolidPeso molecular:774.77BGC-20-1531 hydrochloride(1186532-61-5 free base)
CAS:<p>BGC-20-1531 hydrochloride(1186532-61-5 free base) (GTPL3380 hydrochloride) is a EP4 antagonist for the treatment of acute migraine.</p>Fórmula:C26H25ClN2O6SPureza:98.94% - 99.85%Cor e Forma:SolidPeso molecular:529Bromodiphenhydramine hydrochloride
CAS:<p>Bromodiphenhydramine hydrochloride is a new antihistaminic in the control of cutaneous.</p>Fórmula:C17H21BrClNOPureza:97.29%Cor e Forma:SolidPeso molecular:370.71Benzotript
CAS:<p>Benzotript is an gastrin-receptor antagonist, with anti-gastrinic.</p>Fórmula:C18H15ClN2O3Pureza:97.82%Cor e Forma:SolidPeso molecular:342.776Syk Inhibitor II dihydrochloride
CAS:<p>Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.</p>Fórmula:C14H17Cl2F3N6OPureza:98.53%Cor e Forma:SolidPeso molecular:413.22Nonapeptide-1
CAS:<p>Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions.</p>Fórmula:C61H87N15O9SPureza:100%Cor e Forma:SolidPeso molecular:1206.5Xanthine amine congener hydrochloride
CAS:<p>Xanthine amine congener (XAC) hydrochloride is a non-selective adenosine receptor antagonist that induces convulsions in mice.</p>Fórmula:C21H29ClN6O4Cor e Forma:SolidPeso molecular:464.95Tripelennamine
CAS:<p>Tripelennamine: ethylenediamine derivative, H1-receptor blocker, reduces allergic reactions, treats rhinitis and conjunctivitis.</p>Fórmula:C16H21N3Cor e Forma:SolidPeso molecular:255.36ACTH 1-14 acetate(25696-21-3 free base)
<p>ACTH 1-14 acetate regulates cortisol and androgen, is part of the hypothalamic-pituitary-adrenal stress response.</p>Fórmula:C79H113N21O22SPureza:>99.99%Cor e Forma:SolidPeso molecular:1740.96LM11A-31 dihydrochloride
CAS:<p>LM11A-31 dihydrochloride is a water-soluble, BBB-penetrating p75NTR ligand and proNGF antagonist.</p>Fórmula:C12H27Cl2N3O2Pureza:99.9%Cor e Forma:SolidPeso molecular:316.27Fuscoside
CAS:Fuscoside (OPC-21268) is a non-peptide arginine vasopressin (AVP) receptor VI antagonist with an IC50 value of 0.4 μM.Cost-effective and quality-assured.Fórmula:C26H31N3O4Pureza:98.13% - 99.66%Cor e Forma:SolidPeso molecular:449.54AdipoRon
CAS:<p>AdipoRon (SC-396658) is an orally bioavailable adiponectin receptor agonist. It can combine with AdipoR1/2 (KD: 1.8/3.1 μM).</p>Fórmula:C27H28N2O3Pureza:97.90% - 99.86%Cor e Forma:SolidPeso molecular:428.52Chlorpheniramine
CAS:<p>Chlorpheniramine is an H1 anti-histamine agent for IgE-mediated inflammation that is commonly used for allergic diseases.</p>Fórmula:C16H19ClN2Cor e Forma:SolidPeso molecular:274.79Zuclopenthixol dihydrochloride
CAS:<p>Zuclopenthixol dihydrochloride is an D1 and D2 dopamine receptors antagonist.</p>Fórmula:C22H27Cl3N2OSPureza:98%Cor e Forma:SolidPeso molecular:473.89Frovatriptan Succinate
CAS:<p>Frovatriptan Succinate is a synthetic triptan with 5-HT1B/1D receptors agonist activity. It is indicated for the acute treatment of migraine.</p>Fórmula:C18H25N3O6Cor e Forma:SolidPeso molecular:379.41Alizapride
CAS:<p>Alizapride is an antagonist of dopamine receptor. Alizapride can be used in human digestive disorders which is a potent antiemetic [1] [3].</p>Fórmula:C16H21N5O2Cor e Forma:SolidPeso molecular:315.37Lys-[Des-Arg9]Bradykinin,TFA
<p>Lys-[Des-Arg9]Bradykinin,TFA is Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2</p>Fórmula:C54H75F6N13O15Pureza:97.35%Cor e Forma:SolidPeso molecular:1260.24Vazegepant hydrochloride
CAS:Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.Fórmula:C36H47ClN8O3Pureza:98.93%Cor e Forma:SolidPeso molecular:675.3LUN42518 HCl 47142-51-8(free base)
<p>LUN42518 HCl is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.</p>Fórmula:C17H20ClN3OPureza:99.96%Cor e Forma:SolidPeso molecular:317.81Eltoprazine
CAS:<p>Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.</p>Fórmula:C12H16N2O2Cor e Forma:SolidPeso molecular:220.27Bromodiphenhydramine
CAS:<p>Ambodryl, an antihistamine effective against many bacteria, aids in skin allergy studies.</p>Fórmula:C17H20BrNOCor e Forma:SolidPeso molecular:334.25EST64454 hydrochloride
CAS:<p>EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management.</p>Fórmula:C18H23ClF2N4O2Pureza:99.15%Cor e Forma:SolidPeso molecular:400.85Dioxopromethazine
CAS:<p>Dioxopromethazine (Dioxoprothazine) is a drug for the treatment of a cough and expectoration. It also can be used in local anesthesia.</p>Fórmula:C17H20N2O2SPureza:98%Cor e Forma:SolidPeso molecular:316.42Dobutamine
CAS:<p>Dobutamine, a synthetic catecholamine, boosts cardiac output and improves blood flow, mainly targeting β1-AR.</p>Fórmula:C18H23NO3Cor e Forma:SolidPeso molecular:301.38Cimetidine hydrochloride
CAS:<p>Cimetidine (SKF-92334) is an oral H2 blocker with Ki 0.6 μM, anti-cancer and anti-inflammatory properties, used for ulcer research.</p>Fórmula:C10H17ClN6SCor e Forma:SolidPeso molecular:288.8Montelukast dicyclohexylamine
CAS:<p>Montelukast (MK0476), a selective CysLT1 antagonist, treats asthma, liver injury, and is researched for COVID-19.</p>Fórmula:C47H59ClN2O3SCor e Forma:SolidPeso molecular:767.5ML-18
CAS:<p>ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.</p>Fórmula:C32H35N5O5Pureza:98.62% - >99.99%Cor e Forma:SolidPeso molecular:569.65Men 10376 TFA(135306-85-3,free)
<p>Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4</p>Fórmula:C59H69F3N12O12Pureza:99.22%Cor e Forma:SolidPeso molecular:1195.25Sarpogrelate
CAS:<p>Sarpogrelate (MCI-9042), an oral 5-HT2 antagonist, boosts platelet aggregation and aids in studying Buerger's disease.</p>Fórmula:C24H31NO6Cor e Forma:SolidPeso molecular:429.51Droxidopa hydrochloride
CAS:<p>Droxidopa (L-DOPS) HCI is an oral norepinephrine precursor for nOH and ADHD research, raising standing BP and easing orthostatic hypotension.</p>Fórmula:C9H12ClNO5Cor e Forma:SolidPeso molecular:249.65Cannabigerol
CAS:Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFórmula:C21H32O2Pureza:99.59% - 99.92%Cor e Forma:SolidPeso molecular:316.48
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