GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(939 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.945 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(358 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5352 produtos de "GPCR/Proteína-G"
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Crotedumab
CAS:<p>Crotedumab (REGN1193) is a humanized antibody targeting GCGR, which reduces fasting blood glucose and improves glucose tolerance, used in diabetes research.</p>Pureza:>95%Cor e Forma:LiquidSulpiride
CAS:<p>Sulpiride (Aiglonyl) is a dopamine D2-receptor antagonist, used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.</p>Fórmula:C15H23N3O4SPureza:99.94%Cor e Forma:White Crystalline PowderPeso molecular:341.43Blonanserin
CAS:<p>Blonanserin (AD-5423), approved in Japan (2008), is an atypical antipsychotic with fewer side effects like EPS, sedation, or hypotension.</p>Fórmula:C23H30FN3Pureza:99.85%Cor e Forma:SolidPeso molecular:367.5Salmeterol
CAS:<p>Salmeterol (GR33343X) is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.</p>Fórmula:C25H37NO4Pureza:99.2% - 99.9%Cor e Forma:SolidPeso molecular:415.57YNT-185
CAS:<p>YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,</p>Fórmula:C33H37N5O5SPureza:99.67%Cor e Forma:SolidPeso molecular:615.74Sertraline hydrochloride
CAS:<p>Sertraline hydrochloride (Sertraline HCl) is a selective serotonin uptake inhibitor that is used in the treatment of depression.</p>Fórmula:C17H18Cl3NPureza:99.12% - 99.89%Cor e Forma:Solid PowderPeso molecular:342.691Urocortin (rat) acetate
<p>Urocortin (rat) acetate: CRF receptor agonist; Ki=13nM (hCRF1), 1.5nM (rCRF2α), 0.97nM (mCRF2β); neuropeptide.</p>Pureza:97.76%Cor e Forma:SoildPIT
CAS:<p>PIT (2,2'-Pyridylisatogen tosylate) is a specific and non-competitive antagonist of the Purinergic receptor P2Y1 with an IC50 of 0.14 μM for human P2Y1.</p>Fórmula:C20H16N2O5SPureza:98.63%Cor e Forma:SolidPeso molecular:396.42UCM-1306
CAS:<p>UCM-1306: an oral dopamine D1 receptor PAM; boosts DA efficacy, may enhance motor and cognitive function in PD.</p>Fórmula:C14H14FNO2SPureza:99.98%Cor e Forma:SoildPeso molecular:279.33Carebastine
CAS:<p>Carebastine, the active metabolite of Ebastine, is an antagonist of the histamine H1 receptor.</p>Fórmula:C32H37NO4Pureza:99.16%Cor e Forma:Off-White SolidPeso molecular:499.64Pizotifen
CAS:<p>Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.</p>Fórmula:C19H21NSPureza:99.93%Cor e Forma:SolidPeso molecular:295.44Alosetron hydrochloride
CAS:<p>Alosetron hydrochloride (GR 68755), a selective 5-HT3 receptor antagonist, can block the actions of serotonin at 5-HT3 sites in the peripheral nervous system.</p>Fórmula:C17H19ClN4OPureza:99.90%Cor e Forma:Off-White PowderPeso molecular:330.81Ethamsylate
CAS:<p>Ethamsylate (Dicynene) 通常用作止血药，增加毛细血管内皮阻力和血小板粘附，抑制前列腺素的生物合成和作用。</p>Fórmula:C10H17NO5SPureza:98.55%Cor e Forma:White Crystals Or Crystalline PowderPeso molecular:263.31Dapoxetine hydrochloride
CAS:<p>Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.</p>Fórmula:C21H23NO·HClPureza:99.70% - 99.91%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:341.87Roluperidone
CAS:<p>Roluperidone (CYR-101) is a novel cyclic amide derivative.</p>Fórmula:C22H23FN2O2Pureza:96.46% - 97.77%Cor e Forma:SolidPeso molecular:366.43GTS-21 dihydrochloride
CAS:<p>GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.</p>Fórmula:C19H20N2O2·2HClPureza:98.54% - >99.99%Cor e Forma:SolidPeso molecular:381.3Olanzapine
CAS:<p>Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.</p>Fórmula:C17H20N4SPureza:99.86% - ≥95%Cor e Forma:Yellowish Crystalline PowderPeso molecular:312.43Clopidogrel hydrogen sulfate
CAS:<p>Clopidogrel hydrogen sulfate is a selective P2Y12 receptor blocker that inhibits platelet adhesion and aggregation.</p>Fórmula:C16H16ClNO2S·H2SO4Pureza:99.57% - 99.79%Cor e Forma:SolidPeso molecular:419.9Delequamine
CAS:<p>Delequamine (RS 15385-197) is a TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.</p>Fórmula:C18H26N2O3SPureza:99.39%Cor e Forma:SolidPeso molecular:350.48Ritodrine hydrochloride
CAS:<p>Ritodrine hydrochloride (NSC 291565), a phenethylamine derivative, reduces uterine contractions by increasing cAMP and decreasing calcium in myometrial cells.</p>Fórmula:C17H21NO3·HClPureza:99% - 99.52%Cor e Forma:SolidPeso molecular:323.82Mebhydrolin napadisylate
CAS:<p>Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergic</p>Fórmula:C19H20N2C10H8O6S2Pureza:99.35% - 99.96%Cor e Forma:White Or Almost White CrystallinePeso molecular:420.52Oxeladin citrate
CAS:<p>Oxeladin citrate: potent, non-addictive cough suppressant safe for all ages and heart patients; no common antitussive side effects.</p>Fórmula:C26H41NO10Pureza:97.23%Cor e Forma:SolidPeso molecular:527.6Retatrutide sodium salt
<p>Retatrutide sodium salt is a glucagon receptor and glucagon-like peptide-1 receptor agonist for the study of type 2 diabetes mellitus.</p>Pureza:99.97%Cor e Forma:Soildp-MPPI hydrochloride
CAS:<p>p-MPPI hydrochloride is a selective antagonist of 5-HT1A receptor, and has antidepressant and anxiolytic-like effects.</p>Fórmula:C25H28ClIN4O2Pureza:99.95%Cor e Forma:SolidPeso molecular:578.87Ziprasidone
CAS:<p>Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.</p>Fórmula:C21H21ClN4OSPureza:99.55%Cor e Forma:Tan SolidPeso molecular:412.94Paroxetine hydrochloride
CAS:<p>Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.</p>Fórmula:C19H21ClFNO3Pureza:98% - 99.99%Cor e Forma:White Crystalline PowderPeso molecular:365.826Proglumide
CAS:<p>Proglumide (Binoside), an anti-ulcer drug, is a CCKA/CCKB antagonist that lowers gastric secretion and gastrointestinal motility.</p>Fórmula:C18H26N2O4Pureza:99.4% - 99.45%Cor e Forma:White Crystalline PowderPeso molecular:334.41Azatadine dimaleate
CAS:<p>Azatadine dimaleate (SCH10649) is an inhibitor for histamine（IC50=6.5 nM） and cholinergic（IC50=10 nM）.</p>Fórmula:C28H30N2O8Pureza:99.7% - >99.99%Cor e Forma:PowderPeso molecular:522.55Tropisetron hydrochloride
CAS:<p>Tropisetron hydrochloride (Tropisetron HCl) is a selective, competitive serotonin 5-HT3 receptor antagonist, with antinauseant and antiemetic activities.</p>Fórmula:C17H21ClN2O2Pureza:99.72% - 99.83%Cor e Forma:SolidPeso molecular:320.82Efloxate
CAS:<p>Efloxate (Angorlisin), a vasodilator, is utilized in the treatment of chronic coronary insufficiency.</p>Fórmula:C19H16O5Pureza:99.66%Cor e Forma:SolidPeso molecular:324.33Azacyclonol
CAS:<p>Azacyclonol (MER 17) is a drug used to diminish hallucinations in psychotic individuals.</p>Fórmula:C18H21NOPureza:99.46%Cor e Forma:Solid PowderPeso molecular:267.37Relenopride
CAS:<p>YKP 10811 (Relenopride) is a novel 5-HT4 receptor partial agonist, which can be used to study irritable bowel syndrome with constipation.</p>Fórmula:C24H30ClFN4O4Pureza:98.98% - 99.76%Cor e Forma:SoildPeso molecular:492.97Solabegron
CAS:<p>Solabegron (GW 427353) is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR</p>Fórmula:C23H23ClN2O3Pureza:97.89%Cor e Forma:SolidPeso molecular:410.89Ramelteon
CAS:<p>Ramelteon (TAK-375) is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist.</p>Fórmula:C16H21NO2Pureza:97.21% - 99.92%Cor e Forma:Crystalline SolidPeso molecular:259.34ONC206
CAS:<p>ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and</p>Fórmula:C23H22F2N4OPureza:99.38% - 99.81%Cor e Forma:SolidPeso molecular:408.44Tolnapersine TFA
<p>Tolnapersine TFA is a mixed dopamine agonist and alpha adrenergic receptor antagonist.</p>Fórmula:C23H27F3N2O3Pureza:99.14%Cor e Forma:SoildPeso molecular:436.47DPTN dihydrochloride
CAS:<p>DPTN dihydrochloride is a potent and selective A3AR antagonist with Ki values of 1.65, 9.61 and 8.53 nM in human, mouse and rat, respectively.</p>Fórmula:C22H20Cl2N4OSPureza:99.95%Cor e Forma:SoildPeso molecular:459.39Evocalcet
CAS:<p>Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).</p>Fórmula:C24H26N2O2Pureza:98.88% - 99.68%Cor e Forma:SolidPeso molecular:374.48AM095 free acid
CAS:<p>AM095 (free acid) is a potent LPA1 receptor antagonist (IC50s: 0.98 and 0.73 μM for recombinant human or mouse LPA1).</p>Fórmula:C27H24N2O5Pureza:99.88%Cor e Forma:SolidPeso molecular:456.49MRGPRX1 agonist 1
CAS:<p>MRGPRX1 agonist 1 is a highly potent MRGPRX1 (Mas-related G-protein-coupled receptor X1)agonist(EC50 of 50 nM).</p>Fórmula:C23H21N3O4SPureza:99.95%Cor e Forma:SolidPeso molecular:435.5Labetalol
CAS:<p>Labetalol: mixed alpha/beta blocker for hypertension, oral or IV; affected by CYP2C19 genetics.</p>Fórmula:C19H24N2O3Pureza:99.87% - 99.89%Cor e Forma:SolidPeso molecular:328.41HJC0197
CAS:<p>HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.</p>Fórmula:C19H21N3OSPureza:98.05%Cor e Forma:SolidPeso molecular:339.45Monatepil 2maleate
<p>Monatepil 2maleate is an orally active Ca2+-channel antagonist and ACAT inhibitor with alpha(1)-adrenergic receptor blocking activity and antiarrhythmic properties that inhibit vasoconstriction.Monatepil 2maleate may be used to study atherosclerosis.</p>Fórmula:C32H34FN3O5SPureza:98%Cor e Forma:SolidPeso molecular:591.69Doxofylline
CAS:<p>Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7.</p>Fórmula:C11H14N4O4Pureza:99.958% - >99.99%Cor e Forma:SolidPeso molecular:266.25N6-Ethyladenosine
CAS:<p>N6-Ethyladenosine is an adenosine derivative, acts as an agonist of Adenosine receptor(hA1AR and hA3AR with Kis of 4.9 and 4.7 nM , respectively).</p>Fórmula:C12H17N5O4Pureza:99.96%Cor e Forma:SolidPeso molecular:295.29Clorprenaline hydrochloride
CAS:<p>Clorprenaline hydrochloride (Clorprenaline HCl) is a beta-2 adrenergic agonist with bronchodilator activity.</p>Fórmula:C11H17Cl2NOPureza:99.59% - >99.99%Cor e Forma:SolidPeso molecular:250.16Bisoprolol hemifumarate
CAS:Bisoprolol, a selective beta-1 adrenergic receptor antagonist, selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart,Fórmula:C20H33NO6Pureza:98.69% - 99.84%Cor e Forma:White To Offf-White PowderPeso molecular:383.49Agomelatine
CAS:<p>Agomelatine (Valdoxan), like melatonin, boosts mood by targeting melatonin and 5-HT2C receptors.</p>Fórmula:C15H17NO2Pureza:99.92%Cor e Forma:White SolidPeso molecular:243.3Triflupromazine hydrochloride
CAS:<p>Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists.</p>Fórmula:C18H20ClF3N2SPureza:99.76% - 99.82%Cor e Forma:CrystalsPeso molecular:388.88CGS 15943
CAS:<p>CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.</p>Fórmula:C13H8ClN5OPureza:97.4%Cor e Forma:SolidPeso molecular:285.69
