GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(939 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.945 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(358 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5352 produtos de "GPCR/Proteína-G"
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Vilazodone Hydrochloride
CAS:<p>Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the</p>Fórmula:C26H27N5O2·HClPureza:99.56% - >99.99%Cor e Forma:SolidPeso molecular:477.99Vanoxerine dihydrochloride
CAS:<p>Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)</p>Fórmula:C28H34Cl2F2N2OPureza:98.16% - 98.35%Cor e Forma:White SolidPeso molecular:523.49Capromorelin Tartrate
CAS:<p>Capromorelin Tartrate (CP 424391-18) is a potent, orally active growth hormone secretagogue receptor (GHSR) agonist (Ki: 7 nM for hGHS-R1a).</p>Fórmula:C32H41N5O10Pureza:97.69%Cor e Forma:SolidPeso molecular:655.7M 1145 acetate
<p>M1145 acetate: chimeric peptide, selective GAL2 agonist, Ki=6.55 nM; >90x affinity vs GAL1, 76x vs GalR3. Enhances galanin signal.</p>Fórmula:C130H209N37O34Pureza:99.1%Cor e Forma:SolidPeso molecular:2834.28Bromodiphenhydramine
CAS:<p>Ambodryl, an antihistamine effective against many bacteria, aids in skin allergy studies.</p>Fórmula:C17H20BrNOCor e Forma:SolidPeso molecular:334.25BML-190
CAS:<p>BML-190 (Indomethacin morpholinylamide) 是一种 CB2 受体的配体，其对 CB2 受体 (Ki:435 nM) 和 CB1受体 (Ki> 2 μM)。</p>Fórmula:C23H23ClN2O4Pureza:97.70%Cor e Forma:SolidPeso molecular:426.89Loxapine hydrochloride
CAS:<p>Loxapine hydrochloride, an oral anti-psychotic, inhibits dopamine and blocks 5-HT receptors.</p>Fórmula:C18H19Cl2N3OCor e Forma:SolidPeso molecular:364.27(±)-Ibipinabant
CAS:<p>(±)-Ibipinabant ((±)-SLV319) has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.</p>Fórmula:C23H20Cl2N4O2SPureza:99.28% - 99.83%Cor e Forma:SolidPeso molecular:487.4CP 376395
CAS:<p>CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.</p>Fórmula:C21H30N2OPureza:99.86% - 99.94%Cor e Forma:SolidPeso molecular:326.48Tianeptine sodium salt
CAS:<p>Tianeptine sodium salt 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Fórmula:C21H24ClN2NaO4SPureza:99.82%Cor e Forma:SolidPeso molecular:458.93Substance P 1-9 aceate
<p>Substance P 1-9 aceate is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.</p>Fórmula:C54H81N15O14Pureza:99.01%Cor e Forma:SolidPeso molecular:1164.31Glucagon-like peptide 1 (1-37), human acetate
<p>Glucagon-like peptide 1 (1-37), human acetate is a highly potent the GLP-1 receptor agonist.</p>Pureza:98%Cor e Forma:LiquidPeso molecular:N/AZuclopenthixol
CAS:<p>Zuclopenthixol (cis-Clopenthixol) is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics.</p>Fórmula:C22H25ClN2OSPureza:98.9% - 99.82%Cor e Forma:SolidPeso molecular:400.96Brompheniramine
CAS:<p>Brompheniramine, an alkylamine antihistamine, targets H1 receptors (Kd=6.06nM) and has anticholinergic/depressant qualities. Blocks Ca/Na/hERG channels.</p>Fórmula:C16H19BrN2Cor e Forma:SolidPeso molecular:319.24Brimonidine
CAS:<p>Brimonidine (Bromoxidine) is a drug used as eye drops under the brand names Alphagan and Alphagan-P.</p>Fórmula:C11H10BrN5Pureza:99.626%Cor e Forma:Yellow SolidPeso molecular:292.13Oxyntomodulin acetate
<p>Oxyntomodulin acetate, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist[1].</p>Pureza:99.24%Cor e Forma:LiquidPeso molecular:N/A7-Amino-4-(trifluoromethyl)coumarin
CAS:7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist.Fórmula:C10H6F3NO2Pureza:97.31% - 97.84%Cor e Forma:Yellow PowderPeso molecular:229.16AZ3451
CAS:<p>AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).</p>Fórmula:C30H27BrN4O3Pureza:98.12%Cor e Forma:SolidPeso molecular:571.46BRL 54443
CAS:<p>BRL 54443 is a potent 5-HT1E/1F receptor agonist (pKi values are 8.7 and 8.9 respectively).</p>Fórmula:C14H18N2OPureza:98.07%Cor e Forma:SolidPeso molecular:230.31Lixisenatide acetate (320367-13-3 free base)
CAS:<p>Lixisenatide acetate is a receptor agonist similar to glucagon-like peptide-1 (glp-1) for the treatment of type 2 diabetes mellitus (T2DM).</p>Fórmula:C215H347N61O65S·6C2H4O2Pureza:98% - 99.9%Cor e Forma:SolidPeso molecular:5218.88BP 897
CAS:<p>BP 897: potent selective dopamine D3 agonist, weak D2 antagonist. Ki: 0.92 nM (D3), 61 nM (D2), low affinity at D1/D4.</p>Fórmula:C26H31N3O2Pureza:99.44%Cor e Forma:SolidPeso molecular:417.54Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:<p>Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-</p>Fórmula:C24H35ClO9Pureza:99.88% - 99.94%Cor e Forma:SolidPeso molecular:502.98MRT-10
CAS:<p>MRT-10 is a Smoothened (Smo) receptor antagonist.</p>Fórmula:C24H23N3O5SPureza:99.73%Cor e Forma:SolidPeso molecular:465.52BRL-15572 hydrochloride
CAS:<p>BRL-15572 hydrochloride: selective h5-HT1D antagonist with high affinity; useful for studying h5-HT1D responses.</p>Fórmula:C25H28Cl2N2OCor e Forma:SolidPeso molecular:443.41Nuciferine
CAS:<p>Nuciferine ((-)-Nuciferine) is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera.</p>Fórmula:C19H21NO2Pureza:98.76% - 99.79%Cor e Forma:SolidPeso molecular:295.38Cenicriviroc
CAS:<p>Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.</p>Fórmula:C41H52N4O4SPureza:97.87%Cor e Forma:SolidPeso molecular:696.94Neuropeptide EI, rat acetate
<p>Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.</p>Fórmula:C65H102N16O25Pureza:95.55%Cor e Forma:SolidPeso molecular:1507.6Maraviroc
CAS:<p>Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s—MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.</p>Fórmula:C29H41F2N5OPureza:97.13% - 99.59%Cor e Forma:Brown SolidPeso molecular:513.67AM095
CAS:<p>AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.</p>Fórmula:C27H23N2NaO5Pureza:98.87%Cor e Forma:SolidPeso molecular:478.47Hydroxyzine dihydrochloride
CAS:<p>Hydroxyzine dihydrochloride treats allergies, pruritus, anxiety; causes drowsiness; also an antiemetic and sedative.</p>Fórmula:C21H27ClN2O2·2HClPureza:99.46% - 99.79%Cor e Forma:Oil PowderPeso molecular:447.83MK-571 sodium
CAS:<p>MK-571 sodium, a CysLT1 antagonist and MRP2 inhibitor, obstructs drug efflux and hampers enterocyte phase-2 conjugation of flavonoids.</p>Fórmula:C26H27ClN2O3S2·NaPureza:97.86% - 99.58%Cor e Forma:SolidPeso molecular:537.07(R)-Propranolol hydrochloride
CAS:<p>(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol.</p>Fórmula:C16H22ClNO2Pureza:98.63% - 99.01%Cor e Forma:SolidPeso molecular:295.85-Benzyloxygramine
CAS:<p>5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.</p>Fórmula:C18H20N2OPureza:99.13%Cor e Forma:SolidPeso molecular:280.36BIBO3304
CAS:<p>BIBO3304: Selective NPY Y1 blocker, IC50 of 0.38nM (human), 0.72nM (rat); curbs hunger from NPY/fasting when injected centrally.</p>Fórmula:C29H35N7O3Cor e Forma:SolidPeso molecular:529.63CYM 50358 hydrochloride (1314212-39-9 free base)
CAS:<p>CYM50358 HCl is an S1P4 antagonist.</p>Fórmula:C20H19Cl3N2O2Pureza:99.57%Cor e Forma:SolidPeso molecular:425.73CGS 21680 Hydrochloride
CAS:<p>CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.</p>Fórmula:C23H29N7O6·HClPureza:96.74% - 99.53%Cor e Forma:SolidPeso molecular:535.98Midodrine
CAS:<p>Midodrine ((±)-Midodrin), an adrenergic alpha-1 agonist, belongs to the class of medications known as vasopressors.</p>Fórmula:C12H18N2O4Pureza:99.89%Cor e Forma:SolidPeso molecular:254.28Tetradecyl Phosphonate
CAS:<p>Tetradecyl Phosphonate 是溶血磷脂酸 1 (LPA1)、LPA2 和 LPA3 受体的泛拮抗剂。</p>Fórmula:C14H31O3PPureza:99.95%Cor e Forma:White To Off-White PowderPeso molecular:278.372-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
<p>2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.</p>Fórmula:C38H64F3N11O10Pureza:>99.99%Cor e Forma:SolidPeso molecular:891.98EST64454 hydrochloride
CAS:<p>EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management.</p>Fórmula:C18H23ClF2N4O2Pureza:99.15%Cor e Forma:SolidPeso molecular:400.85N-ACETYLTRYPTAMINE
CAS:<p>N-ACETYLTRYPTAMINE is a partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.</p>Fórmula:C12H14N2OPureza:98.79%Cor e Forma:PowderPeso molecular:202.25AnaMorelin hydrochloride
CAS:<p>AnaMorelin hydrochloride (RC-1291 hydrochloride) is a novel ghrelin receptor agonist(EC50 : 0.74 nM, in the FLIPR assay).</p>Fórmula:C31H43ClN6O3Pureza:99.18% - ≥98%Cor e Forma:SolidPeso molecular:583.16GR 125743
CAS:<p>GR 125743 is a novel antagonist of 5-HT1B/1D receptor.</p>Fórmula:C25H28N4O2Pureza:99.76%Cor e Forma:SolidPeso molecular:416.52Harmine
CAS:<p>Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.</p>Fórmula:C13H12N2OPureza:98.29% - 99.92%Cor e Forma:Off-White SolidPeso molecular:212.25MK-0557
CAS:<p>MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM).</p>Fórmula:C22H19FN4O3Pureza:99.88%Cor e Forma:SolidPeso molecular:406.41OXA (17-33) acetate
<p>OXA (17-33) acetate is a more potent agonist of orexin-1 receptor (OX1, EC50 = 8.29 nM)) over OX2 (EC50 = 187 nM).</p>Fórmula:C79H125N23O22Pureza:98.52%Cor e Forma:SolidPeso molecular:1748.98Ramosetron hydrochloride
CAS:<p>Ramosetron hydrochloride (YM-060) is a serotonin 5-HT3 receptor antagonist. It is used to treat diarrhea-predominant irritable bowel syndrome and nausea.</p>Fórmula:C17H18ClN3OPureza:99.95%Cor e Forma:SolidPeso molecular:315.8CYM5442
CAS:<p>CYM5442 is an S1P agonist, targeting to Sphingosine.</p>Fórmula:C23H27N3O4Pureza:98.02% - 99.48%Cor e Forma:SolidPeso molecular:409.48SBI-553
CAS:<p>SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 μM).</p>Fórmula:C26H31FN4O2Pureza:99.33%Cor e Forma:SolidPeso molecular:450.55Norfluoxetine Hydrochloride
CAS:<p>Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.</p>Fórmula:C16H17ClF3NOPureza:99.71%Cor e Forma:SolidPeso molecular:331.76
