GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(939 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.945 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(358 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5352 produtos de "GPCR/Proteína-G"
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Ibutamoren
CAS:<p>Ibutamoren (MK-677) is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It also alters the metabolism of body fat and so may have an application in the treatment of obesity.</p>Fórmula:C27H36N4O5SPureza:97.59%Cor e Forma:SolidPeso molecular:528.66Perospirone hydrochloride
CAS:<p>Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia.</p>Fórmula:C23H31ClN4O2SPureza:99.37%Cor e Forma:White SolidPeso molecular:463Namodenoson
CAS:<p>Namodenoson (2-Cl-IB-MECA) is an adenosine A3 receptor agonist.</p>Fórmula:C18H18ClIN6O4Pureza:98.97%Cor e Forma:SolidPeso molecular:544.73β-MSH (1-22) (human) acetate
Beta-MSH (1-22) (human) acetate (Beta-MSH (1-22) (human) acetate (17908-57-5 Free base)) , is an endogenous melanocortin-4 receptor (MC4-R) agonist.Fórmula:C120H178N34O37SPureza:99.64%Cor e Forma:SolidPeso molecular:2720.97ML-193
CAS:<p>ML-193: GPR55 antagonist, IC50 221nM, 27x selective over GPR35/CB1/CB2, may aid Parkinson's symptoms.</p>Fórmula:C28H25N5O4SPureza:97.74%Cor e Forma:SolidPeso molecular:527.59Cetrorelix diacetate
CAS:<p>Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist.</p>Fórmula:C74H100ClN17O18Pureza:98.38%Cor e Forma:SolidPeso molecular:1551.17Dolasetron Mesylate hydrate
CAS:<p>Dolasetron Mesylate hydrate blocks 5HT3 to prevent chemo and radiotherapy nausea.</p>Fórmula:C20H26N2O7SPureza:99.86% - 99.9%Cor e Forma:SolidPeso molecular:438.49Desvenlafaxine succinate hydrate
CAS:<p>Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).</p>Fórmula:C20H33NO7Pureza:99.26%Cor e Forma:White Crystalline PowdePeso molecular:399.48Zuclopenthixol
CAS:<p>Zuclopenthixol (cis-Clopenthixol) is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics.</p>Fórmula:C22H25ClN2OSPureza:98.9% - 99.82%Cor e Forma:SolidPeso molecular:400.96Tolazoline
CAS:<p>Tolazoline (Benzalolin), a vasodilator, treats vessel spasms and reverses 5-HT2A drug overdose effects.</p>Fórmula:C10H12N2Pureza:99.52%Cor e Forma:SolidPeso molecular:160.22PEN (human) aceate
<p>PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.</p>Fórmula:C99H163N27O34Pureza:99.25%Cor e Forma:SolidPeso molecular:2275.51BMY-25368
CAS:<p>BMY-25368 is a long-acting antagonist of the H2-receptor.</p>Fórmula:C19H25N3O3Cor e Forma:SolidPeso molecular:343.42Cinanserin
CAS:<p>Cinanserin is a serotonin 5-HT2 antagonist.</p>Fórmula:C20H24N2OSCor e Forma:SolidPeso molecular:340.48ACTH 11-24 acetate(4237-93-8 free base)
CAS:<p>ACTH 11-24 acetate is a cortisol-stimulating adrenocorticotrophin fragment and a competitive antagonist of ACTH 1-39 and 1-10.</p>Fórmula:C79H138N24O18Pureza:>99.99%Cor e Forma:SolidPeso molecular:1712.12SB-649868
CAS:<p>SB-649868 (GSK649868) is a potent and selective orally active antagonist of orexin(pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).</p>Fórmula:C26H24FN3O3SPureza:99.53%Cor e Forma:SolidPeso molecular:477.55ELA-14(human) acetate
<p>ELA-14(human) acetate, a fragment of ELA, targets APJ, activates Gαi1 and β-arrestin-2, and prompts receptor internalization like its parent peptide.</p>Fórmula:C77H123N25O19S2Pureza:97.2%Cor e Forma:SolidPeso molecular:1767.09Elagolix sodium
CAS:<p>Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).</p>Fórmula:C32H29F5N3NaO5Pureza:99.71%Cor e Forma:SolidPeso molecular:653.57Bimatoprost
CAS:<p>Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular</p>Fórmula:C25H37NO4Pureza:98% - >99.99%Cor e Forma:Crystalline SolidPeso molecular:415.57ANP(1-28) Acetate (human, porcine)
CAS:<p>Carperitide acetate: 28-amino acid hormone from human heart, counters cardiac injury/stretch, reduces endothelin-1.</p>Fórmula:C129H207N45O41S3Pureza:98.24%Cor e Forma:SolidPeso molecular:3140.5Hemokinin 1 (mouse) acetate(208041-90-1 free base)
<p>Mouse Hemokinin-1 acetate: NK1 receptor agonist, Ki=0.175 nM; NK2 Ki=560 nM.</p>Fórmula:C63H104N22O17SPureza:98.33%Cor e Forma:SolidPeso molecular:1473.72BAR501
CAS:<p>BAR501是高效选择性的 GPBAR1激动剂(EC50:1 μM)。</p>Fórmula:C26H46O3Pureza:99.29% - 99.68%Cor e Forma:SolidPeso molecular:406.64Pancreatic Polypeptide (human) acetate
<p>Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.</p>Pureza:97.26%Cor e Forma:LiquidPeso molecular:N/ANeuromedin N acetate(92169-45-4 free base)
<p>Neuromedin N acetate(92169-45-4 free base) is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct</p>Fórmula:C40H67N7O10Pureza:99.95%Cor e Forma:SolidPeso molecular:805.9Loxiglumide
CAS:<p>Loxiglumide (CR-1505) is an antagonist of cholecystokinin (CCK-1) receptor.</p>Fórmula:C21H30Cl2N2O5Pureza:97.55% - 99.81%Cor e Forma:SolidPeso molecular:461.38SB 204741
CAS:<p>SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.</p>Fórmula:C14H14N4OSPureza:99.83%Cor e Forma:SolidPeso molecular:286.35TG6-10-1
CAS:<p>TG6-10-1 is an EP2 antagonist.</p>Fórmula:C23H23F3N2O4Pureza:99.66% - ≥95%Cor e Forma:SolidPeso molecular:448.43Carcinine ditrifluoroacetate Acetate
<p>Carcinine ditrifluoroacetate Acetate (β-Alanylhistamine dihydrochloride) is an H3 receptor antagonist.</p>Fórmula:C14H20F6N4O7Pureza:98.18%Cor e Forma:SolidPeso molecular:470.32Dioxopromethazine
CAS:<p>Dioxopromethazine (Dioxoprothazine) is a drug for the treatment of a cough and expectoration. It also can be used in local anesthesia.</p>Fórmula:C17H20N2O2SPureza:98%Cor e Forma:SolidPeso molecular:316.42Rizatriptan benzoate
CAS:<p>Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine</p>Fórmula:C22H25N5O2Pureza:99% - 99.79%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:391.47Ipragliflozin
CAS:<p>Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.</p>Fórmula:C21H21FO5SPureza:99.38% - 99.70%Cor e Forma:SolidPeso molecular:404.45BP 897
CAS:<p>BP 897: potent selective dopamine D3 agonist, weak D2 antagonist. Ki: 0.92 nM (D3), 61 nM (D2), low affinity at D1/D4.</p>Fórmula:C26H31N3O2Pureza:99.44%Cor e Forma:SolidPeso molecular:417.54ML417
CAS:<p>ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).</p>Fórmula:C22H25N3O3Pureza:98.4% - 99.42%Cor e Forma:SolidPeso molecular:379.45Alloxazine
CAS:<p>Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.</p>Fórmula:C10H6N4O2Pureza:99.75%Cor e Forma:SolidPeso molecular:214.18β-CGRP, human acetate
<p>β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptor</p>Fórmula:C164H271N51O50S3Pureza:99.35%Cor e Forma:SolidPeso molecular:3853.46Chlorphenoxamine
CAS:<p>Chlorphenoxamine (Contristamine) is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent.</p>Fórmula:C18H22ClNOPureza:99.44% - 99.85%Cor e Forma:SolidPeso molecular:303.83ML-178
CAS:<p>ML-178: selective S1PR4 agonist, EC50 of 46 nM; inactive on other S1P receptors at 25 μM.</p>Fórmula:C13H9Br2Cl2NO2Pureza:95.92%Cor e Forma:SolidPeso molecular:441.93PSB-SB-487
CAS:<p>PSB-SB-487 is antagonist of GPR55.</p>Fórmula:C26H32O4Pureza:98.53%Cor e Forma:SolidPeso molecular:408.53Risperidone hydrochloride
CAS:<p>Risperidone hydrochloride blocks 5-HT2, inhibits P-glycoprotein, and antagonizes D2 receptors (Ki: 5-HT2A - 4.8 nM, D2 - 5.9 nM).</p>Fórmula:C23H28ClFN4O2Cor e Forma:SolidPeso molecular:446.95Opaganib
CAS:<p>Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).</p>Fórmula:C23H25ClN2OPureza:98.86% - 99.85%Cor e Forma:SolidPeso molecular:380.91Dimemorfan phosphate
CAS:<p>Dimemorfan phosphate (3,17-dimethylmorphinan) is a sigma 1 receptor agonist. Dimemorfan phosphate is used as a potent antitussive.</p>Fórmula:C18H25N·H3O4PPureza:99.65%Cor e Forma:SolidPeso molecular:353.4Scyliorhinin II acetate
<p>Scyliorhinin II acetate is a selective agonist of the neurokinin-3 (NK3) receptor (Ki = 2.5 nM) in rat cerebral cortex.</p>Fórmula:C79H123N21O28S3Pureza:99.06%Cor e Forma:SolidPeso molecular:1911.14Anisotropine Methylbromide
CAS:<p>Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.</p>Fórmula:C17H32BrNO2Pureza:99.73%Cor e Forma:Crystals From Acetone SolidPeso molecular:362.35PF-06291874
CAS:<p>PF-06291874 (Glucagon receptor antagonists-4) (Glucagon receptor antagonists-4) is a highly effective and orally active antagonist of the glucagon receptor.</p>Fórmula:C26H28F3N3O4Pureza:99.12% - 99.27%Cor e Forma:SolidPeso molecular:503.51Peptide YY (PYY) (3-36), human
CAS:<p>Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.</p>Fórmula:C176H272N52O54Pureza:97.76%Cor e Forma:SolidPeso molecular:3980.42Taprenepag
CAS:<p>Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).</p>Fórmula:C24H22N4O5SPureza:98.89% - 99.15%Cor e Forma:SolidPeso molecular:478.52Medetomidine hydrochloride
CAS:<p>Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.</p>Fórmula:C13H16N2·HClPureza:99.96%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:236.74GLP-1 receptor agonist 9
CAS:<p>1H-Benzimidazole-6-carboxylic acid is a GLP-1 receptor agonist.</p>Fórmula:C32H31ClFN3O5Pureza:98%Cor e Forma:SolidPeso molecular:592.06Betaxolol
CAS:<p>Betaxolol (Kerlone) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.</p>Fórmula:C18H29NO3Pureza:99.01%Cor e Forma:White Crystalline SolidPeso molecular:307.43D3-βArr
CAS:<p>D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct</p>Fórmula:C20H23N5Pureza:98.82%Cor e Forma:SolidPeso molecular:333.43Doxazosin
CAS:<p>Doxazosin (UK 33274) is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms.</p>Fórmula:C23H25N5O5Pureza:99.47% - 99.87%Cor e Forma:SolidPeso molecular:451.48
