GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.949 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5378 produtos de "GPCR/Proteína-G"
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Fenspiride
CAS:<p>Fenspiride: oral non-steroidal anti-inflammatory, treats respiratory infections/otitis, inhibits H1-histamine receptors and PDE 3, 4, 5.</p>Fórmula:C15H20N2O2Cor e Forma:SolidPeso molecular:260.33Tianeptine sodium salt
CAS:<p>Tianeptine sodium salt 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Fórmula:C21H24ClN2NaO4SPureza:99.82%Cor e Forma:SolidPeso molecular:458.93Prucalopride Succinate
CAS:Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).Fórmula:C18H26ClN3O3·C4H6O4Pureza:99.24%Cor e Forma:SolidPeso molecular:485.96Trimethobenzamide hydrochloride
CAS:<p>Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.</p>Fórmula:C21H29ClN2O5Pureza:99.52%Cor e Forma:SolidPeso molecular:424.92CYM 50358 hydrochloride (1314212-39-9 free base)
CAS:CYM50358 HCl is an S1P4 antagonist.Fórmula:C20H19Cl3N2O2Pureza:99.57%Cor e Forma:SolidPeso molecular:425.73Bupranolol
CAS:<p>Bupranolol blocks β2-adrenergic receptor; treats angina, hypertension, glaucoma, arrhythmia, and prevents clots.</p>Fórmula:C14H22ClNO2Pureza:97.63%Cor e Forma:SolidPeso molecular:271.78Flibanserin
CAS:<p>Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder.</p>Fórmula:C20H21F3N4OPureza:99.37% - 99.93%Cor e Forma:White PowderPeso molecular:390.4MK-0557
CAS:<p>MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM).</p>Fórmula:C22H19FN4O3Pureza:99.88%Cor e Forma:SolidPeso molecular:406.41Thrombin Receptor Activator for Peptide
<p>Thrombin Receptor Activator (TRAP) or Coagulation Factor II (1-5), used in CHD research.</p>Fórmula:C32H51F3N8O9Pureza:99.88%Cor e Forma:SolidPeso molecular:748.79SB 242084
CAS:<p>SB 242084 dihydrochloride hydrate is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor.</p>Fórmula:C21H19ClN4O2Pureza:99.75% - ≥98%Cor e Forma:SolidPeso molecular:394.85Brexpiprazole
CAS:<p>Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.</p>Fórmula:C25H27N3O2SPureza:99.06% - 99.96%Cor e Forma:SolidPeso molecular:433.57Zotepine
CAS:<p>Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM,</p>Fórmula:C18H18ClNOSPureza:99.78%Cor e Forma:SolidPeso molecular:331.86PAR-2 Activating Peptide acetate
<p>PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).</p>Fórmula:C31H60N10O9Pureza:98.5% - 99.92%Cor e Forma:SolidPeso molecular:716.88Verucerfont
CAS:<p>Verucerfont (NBI77860) is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) .</p>Fórmula:C22H26N6O2Pureza:99.90%Cor e Forma:SolidPeso molecular:406.48Pimavanserin tartrate
CAS:<p>Pimavanserin tartrate is a potent 5-HT 2A receptor inverse agonist used to treat Parkinson's disease-related psychosis.Cost-effective and quality-assured.</p>Fórmula:C50H68F2N6O4·C4H6O6Pureza:99.24% - 99.98%Cor e Forma:SolidPeso molecular:1005.2JNJ-31020028
CAS:<p>JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity (pIC50=8.07, human; pIC50=8.22, rat).</p>Fórmula:C34H36FN5O2Pureza:95.92% - 99.65%Cor e Forma:SolidPeso molecular:565.68BisfluoroModafinil
CAS:CRL-40940 is a selective dopaminergic reuptake inhibitorFórmula:C15H13F2NO2SPureza:99.19%Cor e Forma:SolidPeso molecular:309.33ETHYL 2-AMINO-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE
CAS:<p>ETHYL 2-AMINO-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE targets the prostaglandin E2 receptor EP2 subtype (human)</p>Fórmula:C14H15NO2SPureza:99.98%Cor e Forma:SolidPeso molecular:261.34Niaprazine
CAS:<p>Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.</p>Fórmula:C20H25FN4OPureza:99.56%Cor e Forma:SolidPeso molecular:356.44RS-127445 hydrochloride
CAS:<p>RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5).</p>Fórmula:C17H17ClFN3Pureza:99.48%Cor e Forma:SolidPeso molecular:317.79Sarpogrelate
CAS:<p>Sarpogrelate (MCI-9042), an oral 5-HT2 antagonist, boosts platelet aggregation and aids in studying Buerger's disease.</p>Fórmula:C24H31NO6Cor e Forma:SolidPeso molecular:429.51ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFórmula:C14H11BrO3Pureza:99.12%Cor e Forma:SolidPeso molecular:307.139Melatonin
CAS:<p>Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.</p>Fórmula:C13H16N2O2Pureza:98% - 99.89%Cor e Forma:Pale Yellow Leaflets From Benzene SolidPeso molecular:232.28ML-031
CAS:ML-031 activated S1P2 with an EC50 value of 1 μM in an S1P reporter assay.Fórmula:C19H20N2O3Pureza:99.21%Cor e Forma:SolidPeso molecular:324.37RU 24969 succinate
CAS:<p>RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.</p>Fórmula:C18H22N2O5Cor e Forma:SolidPeso molecular:346.38SANT-1
CAS:<p>SANT-1 directly binds to Smoothened (Smo) receptor (Kd: 1.2 nM) and inhibits Smo agonist effects (IC50: 20 nM).</p>Fórmula:C23H27N5Pureza:99.98% - >99.99%Cor e Forma:SolidPeso molecular:373.49Atipamezole hydrochloride
CAS:<p>Atipamezole is a synthetic α2 adrenergic receptor antagonist.</p>Fórmula:C14H16N2·HClPureza:99.74%Cor e Forma:SolidPeso molecular:248.75Talnetant
CAS:<p>Talnetant (SB 223412) is a selective NK3 receptor antagonist that can penetrate the brain and modulate dopamine.</p>Fórmula:C25H22N2O2Pureza:97.88%Cor e Forma:SolidPeso molecular:382.45PF-06882961 Tris
CAS:<p>PF-06882961 Tris (UNII-2HJV78O0SS) is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.</p>Fórmula:C35H41FN6O7Pureza:98.74% - 99.79%Cor e Forma:SolidPeso molecular:676.7SB297006
CAS:<p>SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.</p>Fórmula:C18H18N2O5Pureza:99.59%Cor e Forma:SolidPeso molecular:342.35Tafluprost
CAS:<p>Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α.</p>Fórmula:C25H34F2O5Pureza:97.7% - 99.67%Cor e Forma:LiquidPeso molecular:452.53Hemopressin (human, mouse) acetate
<p>Hemopressin: Nonapeptide, α1-hemoglobin derivative, CB1 inverse agonist, isolated from rats, oral, reduces inflammatory pain.</p>Fórmula:C52H83N13O14Pureza:99.86%Cor e Forma:SolidPeso molecular:1114.29Prazosin
CAS:<p>Prazosin (Prazosine), an α1-blocker, acts as an inverse agonist at alpha-1 adrenergic receptors and is used to treat hypertension.</p>Fórmula:C19H21N5O4Pureza:99.86%Cor e Forma:White To Tan Powder SolidPeso molecular:383.4[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate
Broad-spectrum neuropeptide inverse agonist/antagonist; potent at ghrelin receptor (EC50 = 5.2 nM); inhibits cancer growth, induces apoptosis.Fórmula:C81H113N19O14Pureza:97.68%Cor e Forma:SolidPeso molecular:1576.917-Amino-4-(trifluoromethyl)coumarin
CAS:7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist.Fórmula:C10H6F3NO2Pureza:97.31% - 97.84%Cor e Forma:Yellow PowderPeso molecular:229.16Droxidopa hydrochloride
CAS:<p>Droxidopa (L-DOPS) HCI is an oral norepinephrine precursor for nOH and ADHD research, raising standing BP and easing orthostatic hypotension.</p>Fórmula:C9H12ClNO5Cor e Forma:SolidPeso molecular:249.65Treprostinil
CAS:<p>Treprostinil (Orenitram) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).</p>Fórmula:C23H34O5Pureza:99.29%Cor e Forma:SolidPeso molecular:390.51Ciliobrevin A
CAS:<p>Ciliobrevin A (HPI-4) is an inhibitor of hedgehog signaling pathway with an IC50 <10 μM.</p>Fórmula:C17H9Cl2N3O2Pureza:98.54% - 99.57%Cor e Forma:SolidPeso molecular:358.18E7046
CAS:<p>E7046 is a specific, orally bioavailable EP4 antagonist (IC50: 13.5 nM, Ki: 23.14 nM), exhibiting anti-tumor activities.</p>Fórmula:C22H18F5N3O4Pureza:99.86%Cor e Forma:SolidPeso molecular:483.4Cannabigerol
CAS:Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFórmula:C21H32O2Pureza:99.59% - 99.92%Cor e Forma:SolidPeso molecular:316.48[Leu31,Pro34]-Neuropeptide Y (porcine)
CAS:<p>[Leu31,Pro34]-Neuropeptide Y (porcine), is a selective and high affinity agonist of neuropeptide Y (NPY) Y1 receptor with anxiolytic effects.</p>Fórmula:C190H286N54O56Pureza:99.39%Cor e Forma:SolidPeso molecular:4223Piperoxan hydrochloride
CAS:<p>Piperoxan hydrochloride (Benodaine hydrochloride) is an α2 adrenoceptor antagonist.</p>Fórmula:C14H20ClNO2Pureza:99.61%Cor e Forma:SolidPeso molecular:269.77Phenylbiguanide
CAS:<p>Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)</p>Fórmula:C8H11N5Pureza:99.54%Cor e Forma:SolidPeso molecular:177.21JNJ-10229570
CAS:<p>JNJ-10229570 (UNII-N9IX402L35) is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland</p>Fórmula:C22H19N3O2SPureza:98.41%Cor e Forma:SolidPeso molecular:389.47Etelcalcetide hydrochloride
CAS:<p>Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.</p>Fórmula:C38H73N21O10S2HClPureza:>99.99%Cor e Forma:SolidPeso molecular:1353.33SAG
CAS:<p>SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective.</p>Fórmula:C28H28ClN3OSPureza:97.37% - 98.88%Cor e Forma:SolidPeso molecular:490.06Betahistine EP Impurity C
CAS:<p>Betahistine EP Impurity C (NSC19005) is structurally related to Betahistine. Betahistine EP Impurity C is a dimer of Betahistine.</p>Fórmula:C15H19N3Pureza:≥95%Cor e Forma:SolidPeso molecular:241.33Sigma-LIGAND-1 hydrochloride
CAS:<p>Sigma-LIGAND-1 HCl: selective sigma receptor ligand; DTG IC50: 16 nM, PPP IC50: 19 nM; weak D2 receptor affinity, Ki: 4000 nM.</p>Fórmula:C27H34ClNO4Cor e Forma:SolidPeso molecular:472.02DPCPX
CAS:<p>DPCPX (PD 116948) is an A1 adenosine receptor antagonist</p>Fórmula:C16H24N4O2Pureza:99.23% - 99.93%Cor e Forma:White SolidPeso molecular:304.39Nafarelin acetate(76932-56-4 free base)
CAS:Nafarelin acetate (76932-56-4) is a GnRH analog that reduces LH and FSH release, used for estrogen-related treatments.Fórmula:C68H87N17O15Pureza:99.98%Cor e Forma:SolidPeso molecular:1382.55
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