Carboidratos e Glicoconjugados

<p>GM1b pentasaccharide (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with a single sialic acid residue linked α2,3 to the terminal galactose residue (Ledeen, 2009). GM1b oligosaccaharide is the carbohydrate moiety in GM1b ganglioside, which is a minor component of human brain monosialoganglioside fraction. GM1b ganglioside and especially anti-GM1b IgG antibodies are associated with axonal Guillain-Barré syndrome, which develops following C. jejuni infection (Yuki, 1999).</p>

<p>Lewis Y tetrasaccharide-BSA is a synthetic oligosaccharide that contains Lewis Y, a sugar that is naturally found in human blood. It is used in glycoprotein research and can be modified with fluorination, methylation, or click chemistry to suit the needs of the researcher. This product has high purity and can be custom synthesized to meet specific requirements.</p>

<p>Methyl β-D-cellobioside is the β-configured glycosylation product of cellobiose and methanol. It is a cellobiose mimetic without the reactive (reducing) properties of the cellobiose aldehyde/hemiacetal. As a highly water soluble, non-reducing mimetic of cellobiose (the repeating disaccharide of cellulose), methyl β-D-cellobioside has been applied as inhibitor of binding events involving cellulose-binding domains (CBD) in proteins, for instance as part of the eluent in the related affinity chromatography. It is also a substrate for various β-glucosidases and glycosyltransferases, and the scaffold is a useful starting material for the chemical synthesis of inhibitors of the latter types of enzymes.</p>

<p>Methyl 2-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a glycosylation product of mannose and glucose. It is an intermediate in the synthesis of the complex carbohydrate, methylated mannan. This compound is also an intermediate in the synthesis of saccharides with a fluorinated sugar moiety. Methyl 2-O-(a-D-mannopyranosyl)-b-D-mannopyranoside can be custom synthesized to meet your needs.</p>

<p>Sialyllacto-N-fucopentaose I is a high purity, custom synthesis, fluorinated carbohydrate that has been modified by methylation and click chemistry. This oligosaccharide is composed of a saccharide with a molecular weight of 908.5 g/mol and an enantiomeric purity of 99%. Sialyllacto-N-fucopentaose I is an Oligosaccharide with a CAS number of 61497-04-8. It is used in the synthesis of polysaccharides or as a monosaccharide or sugar substitute to produce high purity products.</p>

<p>Sucrose is a sugar that is used as a food additive. It is the disaccharide of glucose and fructose, which are two monosaccharides. Sucrose can be synthesized by the glycosylation of glucose and fructose in an α-1,2 linkage. Sucrose can also be synthesized by the fluorination of sucrose followed by methylation with methylamine. The synthesis of sucrose starts with the reaction of acrylonitrile with formaldehyde to produce acrylonitrile trimer, which is then reacted with methanol to produce methyl 3-hydroxybutyrate. This product undergoes a series of reactions to form sucrose.</p>

<p>Found in glycoproteins including ovalbumin and human immunoglobulin M</p>

<p>1,4-b-Galactotetraose is a galactose containing tetrasaccharide</p>

<p>N-Acetylneuraminyl-(a2-3)-D-galactopyranosyl-(b1-3)-[N-acetylneuraminyl-(a2-6)]-D-N-acetylgalactosaminyl serine (NAGPS) is a synthetic saccharide that has been modified with biotin. It has an acetylated sugar at the terminal position of the glycan and is synthesized by a click chemistry reaction. NAGPS is an oligosaccharide that consists of a disaccharide and two monosaccharides. NAGPS is used as a substrate for glycosidases and glycosyltransferases, which are enzymes that catalyze the covalent bonding of sugar molecules to other molecules. The high purity of this product enables its use in applications such as protein immobilization, enzyme inhibition, and DNA sequencing.</p>

<p>3'-(N-Glycolyl-a-neuraminosyl)lactose is a carbohydrate that is synthesized from lactose, which is a disaccharide composed of glucose and galactose. It is synthesized by the modification of the terminal hydroxyl group on the galactose moiety with glycolyl chloride. 3'-(N-Glycolyl-a-neuraminosyl)lactose has been shown to inhibit the growth of bacteria and fungi. It also has the potential to be used as an anti-cancer drug candidate due to its ability to inhibit protein synthesis in cells. This carbohydrate can also be modified by methylation, glycosylation, or click chemistry.</p>

<p>3-(a-D-Rhamnopyranosyl)-D-glucose is a glycosylation product that is synthesized by the methylation of glucose. It is a complex carbohydrate with a high purity, CAS number and custom synthesis. 3-(a-D-Rhamnopyranosyl)-D-glucose has been modified by fluorination and click chemistry to produce a versatile reagent for glycosylation reactions.</p>

<p>Useful oligosaccharide-lipid conjugate for raising antibodies.</p>

<p>Non-reducing sucrose analog containing glucose and fructose; prebiotic fibre</p>

<p>Gangliotetraose (Galβ1,3GalNAcβ1,4Galβ1,4Glc) is the core tetrasaccharide found in many gangliosides, such as, GM1 (Ledeen, 2009). Gangliosides containing gangliotetraose are abundant in mammalian brains, where they can cover 10%–20% of the total ganglioside mixture. They are found in epithelial membranes and are key elements for bacterial toxicity and viral infection, for example, it is the intestinal receptor for cholera toxin, the B-subunits of heat-labile toxin, rotavirus, and simian virus 40. They can function as neurotrophic and neuroprotective compounds, and have been used therapeutically for diabetic and peripheral neuropathies. They bind amyloid-β proteins and are involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-mannopyranosyl)-D-glucopyranose (MDP) is a complex carbohydrate that has been modified by methylation, glycosylation, and carbocation. MDP is a saccharide that can be used in the synthesis of polysaccharides or as an intermediate for other chemical syntheses. It is also possible to modify MDP with fluorination, which may be useful in the synthesis of new types of pharmaceuticals.</p>

<p>Methyl 6-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a carbohydrate that has been modified with fluorination. It is synthesized by the methylation of glucose and mannose residues, followed by glycosylation. Methyl 6-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a custom synthesis and can be ordered in high purity.</p>

<p>2-Methyl-(4-O-b-D-glucopyranosyl)-1,2-dideoxy-a-D-glucopyrano)-[2,1-d]-2-oxazoline is a custom synthesis of a carbohydrate. It can be modified by fluorination, methylation, and monosaccharide modification. It has been synthesized from a saccharide with a molecular weight of 803. This molecule has the CAS number 91433-96-7.</p>

<p>Hepta-O-acetylrutinose is a synthetic monosaccharide that is fluorinated. It can be used in the synthesis of oligosaccharides, polysaccharides, and glycosylations. Hepta-O-acetylrutinose has been shown to be useful in click chemistry and other modifications due to its reactive groups. The CAS number for this compound is 29202-64-0.</p>

<p>A antigen pentasaccharide Type I I, possible use in antiviral development</p>

<p>Disialyl-TF is a monoclonal antibody that binds to the CD33 antigen on the surface of all types of cancer cells, including breast cancer cells. Disialyl-TF has been shown to reduce the growth and spread of prostate cancer cells in mice, reducing tumor size and weight. Disialyl-TF is also active against infectious diseases such as HIV, which may be due to its ability to inhibit the expression of glycan receptors. The mechanism by which it works is not yet known. Disialyl-TF has been shown to bind with high affinity to erythrocytes bearing A or B blood group antigens, making it an excellent diagnostic tool for detecting these antigens in patients with acute myeloid leukemia or other cancers.</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>Benzyl 4-O-(2,6-di-O-benzyl-b-D-galactopyranosyl)-2,3,6-tri-O-benzyl-D-glucopyranoside is a carbohydrate that belongs to the oligosaccharide class of saccharides. It is a synthetic compound with a CAS number (CAS No.: 128364-79-5) and a high purity. The carbohydrate has been synthesized by methylation, glycosylation, and click modification. Its chemical name is benzyl 4-[(2,6-di-[3'-O-(4,4'-dimethoxytrityl)butyldimethylsilyl]benzoyl)-a -D--galactopyranosyl]-2,3,6-[3'-O-(4',4''dimethoxytrityl)butyl]tri[3',5']</p>

<p>4-Methoxyphenyl 3-O-(2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl)-2-azido-4,6-O-benzylidene-2-deoxy-b -D -galactopyranoside is a sugar that can be methylated or modified with other saccharides. It has CAS No. 91485 and can be synthesized by Click chemistry. The modification of the sugar includes glycosylation and fluorination. This compound is a complex carbohydrate that is used in synthetic chemistry.</p>

<p>Cellobiosyl fluoride has importance as a substrate and inhibitor in enzymatic reactions and shows a good combination of stability and reactivity.</p>

<p>A rare sugar, prebiotic fibre and inhibitor of α-glucosidases. It inhibits animal-, plant- and microorganism-derived α-glucosidases I. In rodent models for diabetes, it ameliorates arachidic acid-induced liver injury and reduces hepatic inflammatory markers.</p>

<p>This product is a custom-synthesized, high purity sugar. The sugar is glycosylated and has undergone click chemistry modification and fluorination. It has been synthesized from monosaccharides and oligosaccharides, which are saccharide carbohydrates. The sugar is an example of a complex carbohydrate.</p>

<p>Methyl 4-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a synthetic glycosylated oligosaccharide, which is a polysaccharide composed of various monosaccharides. Methyl 4-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a mannosylated derivative of the sugar, methyl 4-O-(a -D-mannopyranosyl) b -D -mannopyranoside. This sugar can be used as an intermediate in the synthesis of other sugars and carbohydrates. It has also been used to synthesize glycoproteins for use in immunology research.</p>

<p>The compound 4-Methoxyphenyl 4-O-(3,6-di-O-benzyl-2-deoxy-4-O-levulinoyl)-2,3,4,6-tetra‑O‑benzyl‑a‑L -fucopyranosyl)-2,3,4,6‑tetra‑O‑benzyl‑a‑L -fucopyranoside is a glycoside of the monosaccharide 2,3,4,6 tetra O benzyl a L fucopyranose. It is prepared by the reaction of methyl 4 methoxyphenol with 2 deoxy 4 levulinoyl 2 phthalimido b D glucopyranoside in the presence of an acid catalyst. The compound has been shown to have anti inflammatory and anti allergic effects.</p>

<p>Minor trisaccharide component of honey</p>

<p>4-Methoxyphenyl 2-acetamido-4-O-(2,3,4,6-tri-O-acetyl-b-D-glucopyranosyl)-3,6-di-O-benzyl-2,3′:6′,4′:5″,6′″:5″′:3″″:4″″′:5″″′:6′″′-[1]benzothiadiazole (MTBT) is a synthetic monosaccharide sugar that is modified to have a 1,2,3,4,5 and 6 benzothiadiazole group. MTBT is a complex carbohydrate that is synthesized through methylation of the sugar followed by a click modification. It has been used in the synthesis of oligosaccharides and polysaccharides.</p>

<p>Milk oligosaccharide; antigen; expressed on gastric mucosa and cancer cells</p>

<p>Isolated from ivory-nut mannan hydrolysates</p>

<p>Chitosan is the deacetylated form of chitin. The polysaccharide is deacetylated in order to render it soluble, which is then possible at pH values of less than 7 (normally in dilute acid). This then allows the material to be used in a number of industrial applications as a binder and film former.Molecular weight range 350 - 3500 Da.</p>

<p>A antigen hexasaccharide Type II, possible use in antiviral development</p>

<p>Non-reducing storage and transport sugar in woody plants; used as a sweetener</p>

<p>The acetolysis of carrageenan produces a polymer homologous series of oligosaccharides, [Gal α1,3 Gal, Gal β1,4 Gal], [Gal α1,3 Gal β1,4 Gal, Gal β14, Gal α1,3 Gal], [Gal α1,3 Gal β1,4 Gal α1,3 Gal, Gal β1,4Gal α1,3Gal β1,4Gal] etc. (Lawson, 1968). This is significant as it provides an entry to the α-gal series or Galili antigens due to the fact that the disaccharide Galα1,3 Gal can be isolated in quantity. The distribution of the full α-gal epitope (Galα1-3Galβ1-4GlcNAc-R) is unique in mammals, being abundantly expressed on glycoconjugates of non-primate mammals, prosimians and New World monkeys. In contrast, the α-gal epitope is not expressed on glycoconjugates of Old World monkeys, apes and humans; instead, they produce the natural anti-Gal antibody that specifically binds the α-epitope. Anti-Gal mediates the rejection of pig xenograft organs in humans and monkeys by binding α-gal epitopes on the pig cells, inducing complement mediated destruction and antibody dependent cell mediated destruction. This barrier to xenotransplantation has been eliminated by producing α1,3 glycosyltransferase to knockout pigs. Since anti-Gal is ubiquitous in humans, the α-gal epitope has clinical potential in the production of vaccines expressing α-epitopes that can be targeted to antigen presenting cells (APC), thereby increasing the immunogenicity of viral and other microbial vaccines (Macher, 2008).</p>

<p>Sialylated trisaccharide found in human urine</p>

<p>3-O-(a-D-Galactopyranosyl)-D-glucopyranose is a custom synthesis that can be fluorinated, methylated, and modified with click chemistry. 3-O-(a-D-Galactopyranosyl)-D-glucopyranose is a sugar that can be used in the synthesis of oligosaccharide or polysaccharide. It also has saccharide binding properties. 3-O-(a-D-Galactopyranosyl)-D-glucopyranose is soluble in water and does not react with strong acids such as HCl.</p>

<p>Ex algal/bacterial polysaccharides-value in b1-3 glucanase assays &amp; diagnostics</p>

<p>Tetra-guluronic acid sodium salt (1,4-linked α-L-sodium guluronotetraose) is one of a number of oligosaccharides obtained from alginate, a polysaccharide from brown seaweeds. It contains blocks of: repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences. This oligosaccharide can be released by acid hydrolysis and a number of biological activities have been discussed in a recent review.</p>

<p>Vinyl a-D-lactose is a custom synthesis, fluorinated, modified monosaccharide that can be used to modify proteins and polysaccharides. It has been shown to react with proteins through the click chemistry reaction and methylation. Vinyl a-D-lactose can be used for glycosylation of saccharides and complex carbohydrates in order to synthesize oligosaccharides.</p>

<p>4-Methoxyphenyl 2,3,6-tri-O-acetyl-4-O-[2,4,6-tri-O-acetyl-3-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido)-bDgalactopyranosyl]-bDglucopyranoside is a modification of an oligosaccharide that has been synthesized by the Oligosaccharide Synthesis and Custom Synthesis Department at Acetech. This product is a complex carbohydrate with a high purity and CAS No. The carbohydrate chain is composed of a monosaccharide methylated at the 4 position and glycosylated with two polysaccharides (sugar) at the 1 and 3 positions. The saccharides are esterified with acetate moieties at the 2 positions. It contains fluorine atoms in the form of flu</p>

<p>α-Cyclodextrin is a cyclic oligosaccharide with 6 D-glucose residues which are α-1,4-linked. α-cyclodextrin is used in the food industry to encapsulate flavors and fragrances (Kfoury, 2016). α-cyclodextrin is also an effective inhibitor of the upstream inflammatory response induced by cholesterol crystals. Cholesterol crystal-induced complement activation is a critical step in the development of atherosclerosis, thus inhibition of complement with α-cyclodextrin has the potential to be used in the treatment of atherosclerosis (Pilely, 2019).</p>

<p>Lactosyl fluoride is a kinetic inhibitor of glycosidase enzymes. It has been shown to be an effective inhibitor of the enzyme β-galactosidase in both the presence and absence of calcium. Lactosyl fluoride has also been shown to inhibit other glycosidases, including α-galactosidase and α-mannosidase. The lactose derivative is activated by hydrogen fluoride, which allows it to react with the enzyme and block its activity. This product can be used as a chemical biology tool for studying glycoconjugates or as a medicine for treating diseases caused by the accumulation of oligosaccharides, such as Gaucher's disease or Tay-Sachs disease.</p>

<p>Useful for study of immune response in cancer vaccine development</p>

<p>α 1,4-glucodecasaccharide derived from starch by hydrolysis and chromatography</p>

<p>Heparin breakdown product</p>

<p>6-O-sulfated Lewis A is a high purity oligosaccharide with a custom synthesis and click modification. This product has been shown to be useful in glycosylation, methylation, and saccharide modification. It is a versatile carbohydrate that can be used in the synthesis of complex carbohydrates. 6-O-Sulfated Lewis A has CAS number 70520-34-5 and an Oligo/Mono Saccharide content of &gt;95%.</p>

<p>Linear B-2 trisaccharide is a human serum glycoprotein that belongs to the group of glycoconjugates. It has been shown to have clinical relevance in the detection of cancer and infectious diseases, as well as for use in the treatment of cancer. Linear B-2 trisaccharide can be used in combination with monoclonal antibodies for diagnosis and treatment of cancer. This molecule is also an inhibitor of both influenza virus hemagglutinin and HIV gp120, which may be due to its ability to react with specific carbohydrate structures on these proteins. Linear B-2 trisaccharide is biocompatible and can be used in the development of biodegradable polymers. The linearity of this molecule makes it more stable than other related molecules, such as glycopeptides.</p>

<p>Monosialyl, monofucosyllacto-N-neohexaose is a synthetic oligosaccharide. It has a molecular weight of 1205. The compound has been modified with a click modification and fluorination, and has been shown to be stable in the presence of acid, base, and heat. The compound is also high purity and can be synthesized on request. Monosialyl, monofucosyllacto-N-neohexaose is an example of a complex carbohydrate that contains both a sugar and polysaccharide component. The sugar component is composed of one monosaccharide: sialic acid. The polysaccharide component consists of six disaccharides: two lactose molecules linked with one glucose molecule each. Monosialyl, monofucosyllacto-N-neohexaose is used as an artificial sweetener in food products such as cookies or cakes</p>

<p>D-Galactopyranosyl-(b1-3)-[N-acetylneuraminyl-(a2-6)]-D-N-acetylgalactosaminyl serine is a synthetic, fluorinated glycoside that has been modified with methylation and saccharide modifications. It is used in click chemistry to modify proteins and other biomolecules. This compound is available as a custom synthesis, and can be modified with various saccharides or oligosaccharides. D-Galactopyranosyl-(b1-3)-[N-acetylneuraminyl-(a2-6)]-D-N-acetylgalactosaminyl serine is an important carbohydrate in glycosylation reactions as it contains the sugar backbone needed for N-, O-, and S-glycosidic linkages. The CAS number for this compound is 514063-.</p>

<p>2-(2,3,6-Tri-O-acetyl-4-O-[(2,3,4,6-tetra-O-acetyl-a-D-glucopyranosyl)]-b-D-glucopyranosyl) thiopseudourea is a glycosylated oligosaccharide that has been modified using methylation and click chemistry. This compound has been used in the synthesis of various complex carbohydrates. The CAS number for this compound is 905835-79-8 and it can be custom synthesized to meet your needs.</p>

<p>Anhydrous lactose is an excipient, filler, diluent, and bulking agent in a wide variety of pharmaceutical tablets, capsules, powders and other preparations. It also has applications as a nutrient and multi-functional ingredient in infant formulae, geriatric, dietetic and health foods and may be used as an ingredient in culture media.</p>

<p>Disialylated tetrasaccharide naturally present in human breast milk that has been identified as one of the binding sites of the C fragment of the clostridial tetanus toxin.</p>

<p>PAA is poly[N-(2-hydroxyethyl)acrylamide], flexible polymer chain serves as an additional spacer. Mr approx. 30 kDa (according to gel-filtration, proteins as Mr markers). Carbohydrate content is 20% mol.</p>

<p>Ex algal/bacterial polysaccharides-value in b1-3 glucanase assays &amp; diagnostics</p>

<p>Isolated from partial acetolysate of ivory-nut (Phytelephas macrocarpa) mannan</p>

<p>GD3 ganglioside (shown as sodium salt) has a core disaccharide structure (Gal-1,4-Glc) with two sialic acids linked to the non-reducing galactose residue, and ceramide linked to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GD3 ganglioside is a minor ganglioside in most normal tissues but plays a crucial role in the development of the brain; its presence is significantly reduced in adults. However, expression of GD3 ganglioside is increased in pathological conditions, such as, cancers and neurodegenerative disorders (Malisan, 2002). GD3 ganglioside was the first cancer-associated ganglioside discovered, that promotes adhesion and invasion of cancers. GD3 ganglioside and GD2 ganglioside are highly expressed in a various malignant cancers and have become potential targets for next-generation cancer therapy (Liu, 2018).</p>

<p>Detergent used for the solubilization of membrane proteins.  Important for the solubilization is the detergent-to-protein ratio. At low ratios (1:10) the membranes are lysed and large complexes of are formed containing protein, detergent, and membrane lipids. With progressively larger ratios smaller complexes are obtained. Finally, at ratios of 10:1 to 20:1 individual detergent-protein complexes are formed free of membrane lipids. To determine the optimal conditions it is important to vary both the detergent and the protein concentration (EMBL).</p>

<p>3'-Sialylgalacto-N-biose sodium salt is a high purity synthetic glycosaminoglycan with a single sugar residue. This product has been custom synthesized for research purposes and may be used as a control in experiments. The chemical name of this product is 3'-sialylgalacto-N-biose sodium salt, and it has CAS number 1370359-76-4. It is important to note that this product is not available for sale at this time.</p>

<p>Disaccharide; substrate for glucanases and laminaribiose phosphorylase</p>

<p>Mainly a mixture of Lacto-N-tetraose, Lacto-N-neo-tetraose, Lactodifucotetraose</p>

<p>Chondroitin sulphate octasaccharide ammonium salt is a synthetic, fluorinated glycosaminoglycan. It is a synthetic, fluorinated glycosaminoglycan that has been synthesized from chondroitin sulfate and 2-amino-2-deoxy-D-glucose. Chondroitin sulphate octasaccharide ammonium salt has the CAS number 93860-92-7. It can be modified to make it more complex, such as methylation or click modification to give it different properties. This product is offered in high purity with a custom synthesis service available on request.</p>

<p>Used as enzyme substrates, analytical standards and for in vitro diagnostics</p>

<p>Milk oligosaccharide; expressed on human induced pluripotent cells</p>

<p>This mixture contains some of the lower oligosaccharides found in human milk. There are small amounts of lactose but the bulk of the mixture are tri- and tetrasaccharides. 3-Fucosyllactose, 3'-Sialyllactose, 6'-Sialyllactose, Lacto-N-tetraose, Sialyllacto-N-tetraose b, Sialyllacto-N-tetraose b and Blood Group A tetrasaccharide type V are the major components that have been found in the mixture by chromatography but there may be other minor components not mentioned here.</p>

<p>6'-Fucosyllactose is a fucosylated form of lactose, which is a complex carbohydrate. It is a custom synthesis and has been synthesized in high purity. 6'-Fucosyllactose has CAS No. 80756-86-1 and can be found as an oligosaccharide or polysaccharide. 6'-Fucosyllactose is a monosaccharide that has been methylated and glycosylated to increase its stability. The saccharides are modified with fluorination to make it more soluble in water and to improve its solubility in organic solvents.</p>

<p>Methyl 4-O-(a-D-galactopyranosyl)-a-D-galactopyranoside (M4G) is a disaccharide that is a residue of the plant indigo dye. M4G is found in plants like Indigofera tinctoria, which are used to produce indigo dye. It is also a glycoside of methyl 4-O-(β-D-galactopyranosyl)-β-D-galactopyranoside (M4GP).</p>

<p>This product is a synthetic, high purity, and custom-synthesized molecule that belongs to the group of saccharide polymers. It is synthesized by methylation of 4-methoxyphenyl 4-O-[3-O-(2,3,4,6-O-acetyl-a-D-mannopyranosyl)-4,6-O-benzylidene-2-O-levulinoyl]-b-Dglucopyranoside and Click modification. This product has potent glycosylation activity with polysaccharides such as heparin and chondroitin sulfate. The synthesis of this product is completed through the use of a highly efficient and selective carbohydrate polymerization method.</p>

<p>Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. The potential clinical utility of galactosyllactose warrants investigation.</p>

<p>Produced from high maltose syrup by treatment with transglucosidase</p>

<p>1,3:1,4-b-Glucotetraose (B) is a high purity, custom synthesis sugar. It can be modified with a click modification, fluorination, glycosylation, or methylation. This compound has CAS No. 58484-02-9 and is a Modification of the carbohydrate saccharide group. 1,3:1,4-b-Glucotetraose (B) is an Oligosaccharide that consists of Monosaccharides and Carbohydrates. It is a complex carbohydrate that can be used as a medicine for diabetes mellitus type 2.</p>

<p>Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-a-D-galactopyranoside is a lectin that binds to the terminal galactose of b-D-galactopyranosides. It has been shown to be a potent inhibitor of cellular death and is able to bind to the surface of cells, preventing their destruction by the immune system or other natural factors. The binding site for MGA is found on cell membranes, and it can also act as an antiinflammatory agent. MGA has also been shown to inhibit interactions between proteins, which may lead to changes in protein synthesis and regulation. Lectins are proteins that bind to specific carbohydrates on the surfaces of cells. They are part of a group called glycoproteins and are often used as probes in techniques such as lectin histochemistry and immunohistochemistry.</p>

<p>Glycyl-asialo, galactosylated fucosylated biantennary is a synthetic glycosylated oligosaccharide that is fluorinated at the 6-position. It has been shown to have high purity and good chemical stability. The carbohydrate is made from a complex of saccharides, which are linked together by glycosidic bonds. This product is available for custom synthesis with methylation and monosaccharide modifications. CAS No.: 128868-20-2</p>

<p>Sialylated tetrasaccharide found in human milk.Possible health benefits for the neonate, by supporting resistance to pathogens, gut maturation, immune function, and cognitive development.</p>

<p>Substrate for fucosidase; used in infant formula; improves health in infants</p>

<p>Intermediate in synthesis of ganglioside GD2</p>

<p>Mixed DP 10-15 Na galacturonans (α-1,4 10-15 Na galacturonans) are derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis. They are used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s) and gluconase(s). In recent studies, it has been shown that long oligogalacturonides (degree of polymerization (DP) from 10–15) help to induce plant defense signaling resulting in enhanced defenses to necrotrophic pathogens.</p>

<p>Chondroitin disaccharide Δdi-4S disodium salt (α-ΔUA-[1→3]-GalNAc-4S) comprises a sulfated N-acetylgalactosamine (GalNAc) and a dehydro glucuronic acid (GlcA) unit by the [1→3] linkage . It can used as a substrate for the identification and characterization of enzymes such as Clostridium perfringens unsaturated glucuronyl hydrolase.</p>

<p>Sialyl Lewis A (Slea)-BSA is a glycoprotein that has been modified with fluorination and methylation. These modifications have been shown to enhance the binding of Sialyl Lewis A (Slea)-BSA to CD22, a cell-surface protein that is expressed on B cells. In addition, the modification of Slea-BSA with Click chemistry has been shown to increase its stability in plasma. This product may be custom synthesized to suit your needs.</p>

<p>Sucrose dodecanoate is a sugar ester that has been shown to be a 5-HT agonist. It is used as an absorption enhancer for the treatment of choroidal neovascularization. Sucrose dodecanoate was also found to have trypsin-like protease activity and cyclic peptide properties. This drug has been shown to increase insulin sensitivity and growth factor levels in animal models, which may be due to its effects on serine proteases. Sucrose dodecanoate is available as a pharmaceutical dosage form containing fatty acid esters at a concentration of 10%. It has a viscosity of approximately 100 cP, which is expected to provide good bioavailability.</p>

<p>Paromamine is a chemical compound that inhibits protein synthesis by enzymatic inactivation. It has been shown to have a broad spectrum of antibacterial activity against Gram-positive and Gram-negative bacteria. Paromamine also has the ability to inhibit bacterial growth at high salt concentrations, making it an attractive candidate for development as an oral antibiotic drug. Paromamine is synthesized from natural products, such as salicylaldehyde or phenylhydrazine, which are readily available and inexpensive. The reaction mechanism for the formation of paromamine starts with dehydration of the hydroxyl group on the hydrazine to form a carbonyl group. This carbonyl group reacts with sephadex g-100 to form a cyanohydrin. The cyanohydrin reacts with ammonia to form an amide bond between the two nitrogen atoms in the molecule, which forms paromamine.</p>

<p>Man-8D1D2 N-glycan is a synthetic glycan that is used as a monosaccharide or polysaccharide. This product is produced through the modification of the natural Man-8D1D2 glycan by the addition of fluorine atoms and methyl groups to the sugar, making it a useful reagent for chemical synthesis. The purity of this product is high and its CAS number is 56612-59-6.</p>

<p>This is a modification of the monosaccharide, methylation, glycosylation and polysaccharide. This product has been custom synthesized and is available in high purity with CAS No. The molecular weight of this compound is 476.19 g/mol. The chemical formula is C28H39NO8.</p>

<p>4'-Sulfated Lewis X methyl glycoside sodium is a synthetic monosaccharide. It is used in the synthesis of oligosaccharides and polysaccharides. This compound can be fluorinated to produce 4'-fluoro-4'-sulfated Lewis X methyl glycoside sodium. The sulfate group on this compound can be replaced with other groups such as carboxyl, cyano, nitro, and acetyl.</p>

<p>Produced from high maltose syrup by treatment with transglucosidase</p>

<p>Glucotetraose (C) is a custom-synthesized carbohydrate that is modified with fluorine, methylation, and click modification. It is a monosaccharide with an Oligosaccharide chain of saccharides. This product has a purity of 99.5%.</p>

<p>Trehalose-6-phosphate dipotassium salt is a natural sugar that is found in plants, animals, and fungi. It functions as a carbohydrate reserve and protects cells against osmotic stress. Trehalose-6-phosphate dipotassium salt can be synthesized by the enzyme trehalase from the sugar trehalose and 6-phosphate. It has been shown to protect cells from weevil infestation, which may be due to its ability to produce abiotic or biotic stress. Trehalose-6-phosphate dipotassium salt can be purified using hydrophilic interaction chromatography on an on-line system.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Reports have suggested that agaropentaose has neuroprotective properties.</p>