2-Methoxystypandrone

CAS: 85122-21-0

Ref. TM-TN2775

Informação sobre produto

• Nome: 2-Methoxystypandrone
• Sinónimos: 2Methoxystypandrone, 1,4-Naphthalenedione, 6-Acetyl-5-Hydroxy-2-Methoxy-7-Methyl-, 2-Methoxy-6-acetyl-7-methyljuglone, 6-Acetyl-5-hydroxy-2-methoxy-7-methyl-1,4-naphthalenedione, Naphthoquinone (2-methylstipandrone
• CAS: 85122-21-0

Descrição

2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflammation and oxidative stress for preservation of BBB integrity. 2-Methoxystypandrone concomitantly promotes neurodevelopmental protein expression and endogenous neurogenesis through inactivation of GSK3β to enhance β-catenin signaling for upexpression of neuroprotective genes and proteins.2-Methoxystypandrone has anti-osteoclastogenic effect, could reflect the block of RANKL-induced association of TRAF6-TAK1 complexes with consequent decrease of IkappaB-mediated NF-kappaB and mitogen-activated protein kinases-mediated c-Fos activation pathways and suppression of NFATc1 and other gene expression, essential for bone resorption.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 260.24
• Fórmula: C₁₄H₁₂O₅
• Pureza: 98%
• Cor/forma: Solid