CAS 114-07-8: Erythromycin

Description: Erythromycin is a macrolide antibiotic that is primarily used to treat bacterial infections. It is derived from the bacterium Saccharopolyspora erythraea and is effective against a variety of Gram-positive bacteria and some Gram-negative bacteria. The chemical structure of erythromycin features a large lactone ring, which is characteristic of macrolides, along with several sugar moieties that contribute to its solubility and biological activity. Erythromycin works by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of bacteria. It is commonly used in treating respiratory tract infections, skin infections, and certain sexually transmitted infections. Erythromycin is available in various formulations, including oral tablets, topical ointments, and intravenous preparations. While generally well-tolerated, it can cause side effects such as gastrointestinal disturbances and may interact with other medications due to its effects on liver enzymes. Resistance to erythromycin has been observed in some bacterial strains, which can limit its effectiveness in certain infections.

Formula: C₃₇H₆₇NO₁₃

InChI: InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

InChI key: InChIKey=ULGZDMOVFRHVEP-RWJQBGPGSA-N

SMILES: O=C1OC(CC)C(O)(C)C(O)C(C(=O)C(C)CC(O)(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)C(OC3OC(C)C(O)C(OC)(C)C3)C1C)C

Synonyms:

• (2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (non-preferred name)
• (2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl propanoate (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2R,3S,4R,6S)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• (3R,7R,9R,11R,13S,14R)-6-{[(3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• 6-{[4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• Abboticin
• Abomacetin
• Ak-Mycin
• Aknin
• Dotycin
• Drmysin
• E-Base
• E-mycin
• E.E.S
• EMU
• Emgel
• Ergel
• Eritocina
• Eritrex
• Eritrocina
• Eritromed
• Eritromicina
• Ermycin
• Erthrogran
• Ery Derm
• Ery-Ped
• Ery-Tab
• EryDerm
• Eryacne
• Eryc
• Erycen
• Erycette
• Erycin
• Erycinum
• Erygel
• Erymax
• Erytab
• Erythro
• Erythrocin
• Erythrogran
• Erythroguent
• Erythromast
• Erythromast 36
• Erythromid
• Erythromycin A
• Erythromycine
• Ilocap
• Ilosone
• Ilotycin
• Inderm
• L-alpha-Egg-phosphatidylcholine
• Nsc 55929
• Oxacyclotetradecane, erythromycin deriv.
• Oxacyclotetradecane-2,10-dione, 4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-
• Oxacyclotetradecane-2,10-dione, 4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-
• P.C.E.
• PCE
• Pantomicina
• Pediamycin
• Retcin
• Robimycin
• Statcin
• Staticin
• Stiemycin
• T-Stat
• Theramycin Z
• Torlamicina
• Torlamicna
• Vetwic
• Wintrocin
• Wyamycin-s
• [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
• [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
• Erythromycin

Erythromycin

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Purity: >98.0%(T)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 733.94

Erythromycin, Cell Culture Grade

CAS: 114-07-8

Erythromycin, is used as a macrolide antibiotic protein synthesis inhibitor. It is widely used in …

• Formula: C₃₇H₆₇NO₁₃
• Color and Shape: Crystals or powder or crystalline powder, Translucent or white to pale yellow
• Molecular weight: 733.94

Erythromycin

CAS: 114-07-8

• Formula: C₃₆H₆₅NO₁₃/ C₃₇H₆₇NO₁₂/ C₃₇H₆₇NO₁₃
• Purity: 0.8% / 0.2% / 92.3%
• Color and Shape: White
• Molecular weight: 719.44559 / 717.46633 / 733.46124

Erythromycin for system suitability CRS

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Molecular weight: 733.9268

Erythromycin for microbiological assay CRS

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Molecular weight: 733.9268

Erythromycin RS

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Molecular weight: 733.9268

Third international Standard for Erythromycin

CAS: 114-07-8

Erythromycin A CRS

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Molecular weight: 733.9268

Erythromycin

CAS: 114-07-8

Erythromycin and its derivatives; salts thereof

• Formula: C₃₇H₆₇NO₁₃ErythromycinA
• Color and Shape: White Light Yellow Powder
• Molecular weight: 733.94 Erythromycin A

[3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 733.9267800000002

Erythromycin

CAS: 114-07-8

Erythromycin (E-Mycin) is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by …

• Formula: C₃₇H₆₇NO₁₃
• Purity: 99.26% - 99.57%
• Color and Shape: Hydrated Crystals From Water Physical Description Fluffy Colorless Powder Or Fine White Powder (Ntp 1992)
• Molecular weight: 733.93

Erythromycin

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Purity: Erythromycin A+B+C: 93.0 - 102.0%
• Color and Shape: White or pale yellow powder
• Molecular weight: 733.93

Erythromycin

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Purity: Assay: 96.5% (erythromycin (Typical Value in Batch COA)
• Color and Shape: white powder
• Molecular weight: 733.93g/mol

Erythromycin

CAS: 114-07-8

• Purity: ≥98%
• Molecular weight: 733.93g/mol

Erythromycin (Roxithromycin EP Impurity A)

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 733.94

Pharmaceuticals Mixture 326 200 µg/mL in Methanol

CAS: 103-90-2 114-07-8298-46-4 56296-78-7 58-08-2 723-46-6 738-70-5 93107-08-5

• Color and Shape: Mixture

Erythromycin (mixture of A,B,C) 100 µg/mL in Acetonitrile

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Color and Shape: Single Solution
• Molecular weight: 733.93

(-)-Erythromycin, 98%

CAS: 114-07-8

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₃₇H₆₇NO₁₃
• Purity: 98%
• Color and Shape: White to light yellow, Powder
• Molecular weight: 733.94

Erythromycin (mixture of A,B,C)

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Color and Shape: Neat
• Molecular weight: 733.93

Erythromycin 1000 µg/mL in Acetonitrile

CAS: 114-07-8

• Formula: C₃₇H₆₇NO₁₃
• Color and Shape: Single Solution
• Molecular weight: 733.93