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CAS 148-79-8

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Thiabendazole

Description:
Thiabendazole is a broad-spectrum anthelmintic and antifungal agent, primarily used in veterinary medicine and agriculture. It belongs to the class of benzimidazole derivatives and is characterized by its ability to inhibit the polymerization of tubulin, thereby disrupting microtubule formation in cells. This mechanism makes it effective against a variety of parasitic worms and fungi. Thiabendazole is typically a white to off-white crystalline powder, with low solubility in water but higher solubility in organic solvents. It has a moderate molecular weight and a relatively stable structure under normal conditions. The substance is often used in formulations for treating infections in livestock and as a fungicide in crops. While generally considered safe when used as directed, it can pose risks to human health and the environment if misused. Proper handling and adherence to safety guidelines are essential when working with this compound. Additionally, its use is regulated in many countries, reflecting the need for responsible application in both agricultural and medical contexts.
Formula:C10H7N3S
InChI:InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)
InChI key:InChIKey=WJCNZQLZVWNLKY-UHFFFAOYSA-N
SMILES:C=1(NC=2C(N1)=CC=CC2)C3=CSC=N3
Synonyms:
  • 1H-Benzimidazole, 2-(4-thiazolyl)-
  • 2-(1,3-Thiazol-4-Yl)-1,3-Benzothiazole
  • 2-(1,3-Thiazol-4-Yl)-1h-Benzoimidazole
  • 2-(1,3-Thiazol-4-Yl)Benzimidazole
  • 2-(1,3-Thiazol-4-yl)-1H-1,3-benzodiazole
  • 2-(1,3-Thiazol-4-yl)-1H-benzimidazole
  • 2-(4'-Thiazoyl)benzimidazole
  • 2-(4-Thiazolyl)-1H-benzoimidazole
  • 2-(4-Thiazolyl)-1h-Benzimidazole
  • 2-(4-Triazolyl)benzimidazole
  • See more synonyms
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