CAS 50-27-1
:Estriol
Description:
Estriol, with the CAS number 50-27-1, is a naturally occurring estrogen and one of the three main estrogens produced by the human body, alongside estradiol and estrone. It is primarily synthesized in the placenta during pregnancy and plays a crucial role in maintaining pregnancy and fetal development. Estriol is characterized by its relatively weak estrogenic activity compared to estradiol and estrone, making it less potent in stimulating estrogen receptors. Chemically, it is a steroid hormone with a molecular formula of C18H24O3, featuring a phenolic structure that contributes to its biological activity. Estriol is often used in hormone replacement therapy, particularly for menopausal symptoms, and is also studied for its potential protective effects against certain hormone-related cancers. Its pharmacokinetics involve rapid metabolism and excretion, primarily through the liver. Due to its specific role in reproductive health, estriol levels are monitored during pregnancy and can be indicative of fetal well-being.
Formula:C18H24O3
InChI:InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1
InChI key:InChIKey=PROQIPRRNZUXQM-ZXXIGWHRSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(C[C@@H](O)[C@@H]2O)[H]
Synonyms:- (16Alpha,17Beta)-Estra-1,3,5(10)-Triene-3,16,17-Triol
- (16α,17β)-Estra-1,3,5(10)-triene-3,16,17-triol
- (8R,13S,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol
- 1,3,5 (10)-Estratriene-3, 16α, 17β-triol
- 1,3,5(10)-Estratriene-3,16a,17b-triol
- 13β-Methyl-1,3,5(10)-gonatriene-3,16α,17β-triol
- 16α,17β-Estriol
- 16α-Estriol
- 16α-Hydroxyestradiol
- 3,16α,17β-Estriol
- 3,16α,17β-Trihydroxyestra-1,3,5(10)-triene
- Aacifemine
- Colpogyn
- Destriol
- ESTRA-1,3,5(10)-TRIENE-3,16α,17β-TRIOL
- Estra-1,3,5(10)-triene-3,16,17-triol, (16α,17β)-
- Estra-1,3,5(10)-triene-3,16alpha,17beta-triol
- Estratriol
- Estriel
- Follicular hormone hydrate
- Gynasan
- Holin V
- Hormomed
- Incurin
- Klimax E
- Klimoral
- Nsc 12169
- OE3
- OE<sub>3</sub>
- Oekolp
- Oestriol
- Ortho-Gynest
- Ovesterin
- Ovestin
- Ovestrion
- Ovo-Vinces
- Theelol
- Tridestrin
- Trihydroxyestrin
- Triovex
- See more synonyms
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Found 23 products.
Estriol
CAS:Formula:C18H24O3Purity:>98.0%(GC)Color and Shape:White to Almost white powder to crystalMolecular weight:288.39Estriol
CAS:EstriolFormula:C18H24O3Purity:99.3%Color and Shape:White To Off-WhiteMolecular weight:288.17254Estriol
CAS:<p>Estrogens and progestins</p>Formula:C18H24O3Color and Shape:White Crystalline Powder CrystalsMolecular weight:288.17254(1S,10R,11S,13R,14R,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,13,14-triol
CAS:Formula:C18H24O3Purity:%Color and Shape:SolidMolecular weight:288.3814Estriol
CAS:<p>Estriol is a major estrogen metabolite with hydroxyl groups at C3, 16-alpha, and 17-beta; it's abundant in pregnancy urine.</p>Formula:C18H24O3Purity:97.97% - 98.55%Color and Shape:Leaflets From Alcohol SolidMolecular weight:288.38Estriol
CAS:Formula:C18H24O3Purity:≤ 2.0%Color and Shape:White to off-white powderMolecular weight:288.3816α-Hydroxy-17β-estradiol-2,4,17-d3
CAS:Purity:98 atom % DColor and Shape:White SolidMolecular weight:291.4016α-Hydroxy-17β-estradiol-2,4-d2
CAS:Purity:98 atom % DColor and Shape:White SolidMolecular weight:290.40Estriol 100 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C18H24O3Color and Shape:Single SolutionMolecular weight:288.38GB 31660.2-2019 Antibiotics Mixture 168 30-100 µg/mL in Methanol
CAS:Controlled ProductColor and Shape:MixtureEstriol
CAS:Controlled Product<p>Applications A metabolite of Estradiol (E888000). An estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929), Huffman, et al.: J. Biol. Chem., 169, 167 (1947),<br></p>Formula:C18H24O3Color and Shape:White To Off-WhiteMolecular weight:288.38Estriol
CAS:Controlled Product<p>Estriol is a steroidal estrogen, which is a naturally occurring hormone primarily sourced from the placenta during pregnancy. Its mode of action involves binding to estrogen receptors, thereby exerting its effects as part of the broader group of estrogens. Estriol has a relatively lower affinity for estrogen receptors compared to estradiol, contributing to its unique pharmacological profile.In scientific research and clinical settings, Estriol is employed in hormone replacement therapy, especially in postmenopausal women, due to its milder estrogenic effects and lower associated risks compared to other estrogens. It is also studied for its potential benefits in urogynecological health, such as the treatment of menopausal symptoms like vaginal atrophy. Furthermore, its application is under investigation for autoimmune conditions such as multiple sclerosis, given its immunomodulatory properties. Ongoing research aims to delineate the therapeutic potential and safety profile of Estriol in various clinical contexts.</p>Formula:C18H24O3Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:288.38 g/mol
![(1S,10R,11S,13R,14R,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,1…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003AAT.jpg&w=3840&q=75)
