CAS 53-16-7

Estrone

Description:

Estrone is a naturally occurring estrogen steroid hormone, classified as a phenolic compound. It is primarily produced in the ovaries, adrenal glands, and peripheral tissues, playing a crucial role in the regulation of the female reproductive system and secondary sexual characteristics. Estrone is characterized by its molecular formula, which consists of carbon, hydrogen, and oxygen atoms, and it has a specific three-dimensional structure that allows it to bind to estrogen receptors in target tissues. This binding initiates various biological responses, including the regulation of the menstrual cycle and maintenance of pregnancy. Estrone is less potent than estradiol, another major estrogen, but it is significant in postmenopausal women, where it becomes the predominant form of estrogen. In addition to its physiological roles, estrone is also studied for its implications in various health conditions, including hormone replacement therapy and its potential link to certain cancers. Its CAS number, 53-16-7, uniquely identifies it in chemical databases, facilitating research and regulatory processes.

Formula: C₁₈H₂₂O₂

InChI: InChI=1/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14?,15-,16?,18+/m1/s1

InChI key: InChIKey=DNXHEGUUPJUMQT-CBZIJGRNSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(CCC2=O)[H]

Synonyms:

• (8R,13S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
• (8R,9S,13S,14S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one
• 1,3,5(10)-Estratrien-3-Ol-17-One
• 3-Hydroxy-1,3,5(10)-estratrien-17-one
• 3-Hydroxy-17-keto-estra-1,3,5-triene
• 3-Hydroxyestra-1,3,5(10)-Trien-17-One
• 3-Hydroxyestra-1,3,5(10)-triene-17-one
• 3-Hydroxyoestra-1,3,5(10)-trien-17-one
• 3beta-Hydroxyestra-1,3,5(10)-trien-17-one
• Aquacrine
• Crinovaryl
• Cristallovar
• Crystogen
• Destrone
• Disynformon
• Endofolliculina
• Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
• Estrol
• Estron
• Estrona
• Estrovarin
• Estrugenone
• Estrusol
• Femestrone Inj.
• Femestrone injection
• Femidyn
• Fermidyn
• Folikrin
• Folipex
• Folisan
• Follestrine
• Follestrol
• Follicular hormone
• Folliculin
• Folliculin (steroid)
• Folliculinum
• Follicunodis
• Follidrin
• Glandubolin
• Hiestrone
• Hormofollin
• Hormovarine
• Kestrone
• Ketodestrin
• Ketohydroxyestrin
• Kolpon
• Menagen
• Menformon
• Nsc 9699
• Oestrin
• Oestroform
• Oestrone
• Oestroperos
• Ovifollin
• Perlatan
• Solliculin
• Theelin
• Thelestrin
• Thelykinin
• Thynestron
• Tokokin
• Unden
• Way 164397
• Wynestron
• beta-Estrone
• Δ1,3,5(10)-Estratrien-3-ol-17-one
• Δ^1,3,5(10)-Estratrien-3-ol-17-one
• Estrone
• OESTRONE (E1)
• 1,3,5-ESTRATRIEN-3-OL-17-ONE
• 3-HYDROXY-ESTRA-1,3,5(10)-TRIEN-17-ONE
• (8R,13S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one
• E 1
• 1,3,5-Oestratrien-3-ol-17-one
• 1,3,5(10)-Oestratrien-3-ol-17-one
• 1,3,5[10]-ESTRATRIENE-3-OL-17-ONE

Estrone

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 270.37

Ref: 3B-E0026

Estrone 1.0 mg/ml in Methanol

CAS: 53-16-7

Color and Shape: Single Solution

Ref: 61-AMP0282.00-01

ESTRONE CRS

CAS: 53-16-7

ESTRONE CRS

Ref: 41-E1700000

Estrone

CAS: 53-16-7

Estrone

Color and Shape: White To Off-White

Ref: 47-860

Estrone

CAS: 53-16-7

Estrogens and progestins

Formula: C₁₈H₂₂O₂

Color and Shape: White Cream Powder

Molecular weight: 270.37 g/mol

Ref: 45-1255001

1,3,5(10)-Estratrien-3-Ol-17-One

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 270.3661

Ref: IN-DA00361G

Estrone

CAS: 53-16-7

Estrone (Aquacrine) is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen.

Formula: C₁₈H₂₂O₂

Purity: 99.09% - 99.57%

Color and Shape: Small White Crystals Or White To Creamy White Crystalline Powder Solid

Molecular weight: 270.37

Ref: TM-T1009

Estrone (Estradiol Hemihydrate EP Impurity A)

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 270.37

Ref: 4Z-E-119

Estrone

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Molecular weight: 270.37

Ref: 7W-GP1507

Estrone

CAS: 53-16-7

Estrone

Purity: ≥98%

Molecular weight: 270.37g/mol

Ref: 54-BUP18515

1,3,5(10)-Estratrien-3-Ol-17-One

CAS: 53-16-7

1,3,5(10)-Estratrien-3-Ol-17-One

Purity: 98%

Molecular weight: 270.37g/mol

Ref: 54-OR1030419

Estrone 100 µg/mL in Acetonitrile

Controlled Product

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Color and Shape: Single Solution

Molecular weight: 270.37

Ref: 04-XA13213230AL

Estrone

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 270.372

Ref: BP-SBP03439

Estrone

Controlled Product

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Color and Shape: White To Off-White

Molecular weight: 270.37

Ref: 04-C13213230

GB 31660.2-2019 Antibiotics Mixture 168 30-100 µg/mL in Methanol

Controlled Product

CAS: 140-66-9, 25154-52-3, 50-27-1, 50-28-2, 53-16-7, 56-53-1, 57-63-6, 80-05-7

Color and Shape: Mixture

Ref: 04-A50000168ME

Estrone RS

CAS: 53-16-7

Color and Shape: White

Ref: 2K-2003000021

Estriol EP Impurity B

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Molecular weight: 270.4

Ref: ST-EA-CP-E28002

Estrone

Controlled Product

CAS: 53-16-7

Impurity Estradiol EP Impurity A/ Ethinylestradiol EP Impurity C
Applications Estrone is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.

Formula: C₁₈H₂₂O₂

Color and Shape: White To Off-White

Molecular weight: 270.37

Ref: TR-E889050

Ethinylestradiol EP Impurity C

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Molecular weight: 270.37

Ref: ST-EA-CP-E21003

Estrone

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Purity: 97.0%

Color and Shape: Solid, Crystalline

Molecular weight: 270.372

Ref: 10-F301492