CAS 53-19-0: Mitotane

Description:Mitotane, with the CAS number 53-19-0, is an organic compound primarily used in the treatment of adrenocortical carcinoma, a rare type of cancer affecting the adrenal glands. It is classified as an antineoplastic agent and functions by inhibiting adrenal steroidogenesis, leading to a reduction in cortisol production. Mitotane is known for its lipophilic nature, which allows it to accumulate in adipose tissue and the adrenal glands, enhancing its therapeutic effects. The compound has a relatively low solubility in water but is soluble in organic solvents. Its mechanism of action involves the destruction of adrenal cortical cells and the alteration of steroid hormone synthesis. Mitotane can have significant side effects, including adrenal insufficiency, gastrointestinal disturbances, and neurotoxicity, necessitating careful monitoring during treatment. Due to its potent effects and potential toxicity, it is typically administered under strict medical supervision. Overall, Mitotane represents a critical option in the management of specific adrenal tumors, highlighting the importance of targeted therapies in oncology.

Formula:C₁₄H₁₀Cl₄

InChI:InChI=1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H

InChI key:InChIKey=JWBOIMRXGHLCPP-UHFFFAOYSA-N

SMILES:ClC1=CC=C(C=C1)C(C=2C=CC=CC2Cl)C(Cl)Cl

Synonyms:
1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichlor
1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane
1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
1-Chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene
2,2,O,P-Tetrachloroethylidenebisbenzene
2,4'-Dichlorodiphenyldichloroethane
2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane
2-(p-Chlorophenyl)-2-(o-chlorophenyl)-1,1-dichloroethane
Benzene, 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-
See more synonyms
Cb 313
Chloditan
Chlodithane
Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-
Lysodren
Mitotan
Mitotane
Mitotano
Nsc 38721
Opeprim
o,p'-DDD
o,p'-Dichlorodiphenyldichloroethane
o,p'-TDE
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane

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Brand	Product data	Purity	Price range	Estimated delivery
	Mitotane-d4 REF: TR-M372502CAS: 53-19-0	- - -	3,864.00 €	Tue 27 May 25
	GB/T 39665-2020 Pesticide Mixture 607 500-1000 μg/mL in Acetone REF: 04-A50000607ACCAS: 1024-57-3 1031-07-8 106-46-7 115-32-2 118-74-1 122-39-4 13171-21-6 15972-60-8 1897-45-6 23950-58-5 2425-06-1 309-00-2 319-84-6 319-85-7 319-86-8 33213-65-9 3424-82-6 50-29-3 50471-44-8 5103-71-9 5103-74-2 53-19-0 55-38-9 58-89-9 60-57-1 60168-88-9 72-20-8 72-54-8 72-55-9 76-44-8 789-02-6 84332-86-5 85509-19-9 88671-89-0 959-98-8	- - -	- - -	Discontinued product