CAS 53-19-0: Mitotane

Description:Mitotane, with the CAS number 53-19-0, is an organic compound primarily used in the treatment of adrenocortical carcinoma, a rare type of cancer affecting the adrenal glands. It is classified as an antineoplastic agent and functions by inhibiting adrenal steroidogenesis, leading to a reduction in cortisol production. Mitotane is known for its lipophilic nature, which allows it to accumulate in adipose tissue and the adrenal glands, enhancing its therapeutic effects. The compound has a relatively low solubility in water but is soluble in organic solvents. Its mechanism of action involves the destruction of adrenal cortical cells and the alteration of steroid hormone synthesis. Mitotane can have significant side effects, including adrenal insufficiency, gastrointestinal disturbances, and neurotoxicity, necessitating careful monitoring during treatment. Due to its potent effects and potential toxicity, it is typically administered under strict medical supervision. Overall, Mitotane represents a critical option in the management of specific adrenal tumors, highlighting the importance of targeted therapies in oncology.

Formula:C₁₄H₁₀Cl₄

InChI:InChI=1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H

InChI key:InChIKey=JWBOIMRXGHLCPP-UHFFFAOYSA-N

SMILES:ClC1=CC=C(C=C1)C(C=2C=CC=CC2Cl)C(Cl)Cl

Synonyms:
1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichlor
1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane
1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
1-Chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene
2,2,O,P-Tetrachloroethylidenebisbenzene
2,4'-Dichlorodiphenyldichloroethane
2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane
2-(p-Chlorophenyl)-2-(o-chlorophenyl)-1,1-dichloroethane
Benzene, 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-
See more synonyms
Cb 313
Chloditan
Chlodithane
Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-
Lysodren
Mitotan
Mitotane
Mitotano
Nsc 38721
Opeprim
o,p'-DDD
o,p'-Dichlorodiphenyldichloroethane
o,p'-TDE
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane

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products per page. Found 42 products.

Product data	Purity	Price range	Estimated delivery
Pesticide-Mix 20 10 µg/mL in Cyclohexane REF: 04-L18000020CYCAS: 1024-57-3 118-74-1 297-78-9 309-00-2 319-84-6 319-85-7 33213-65-9 3424-82-6 465-73-6 50-29-3 53-19-0 58-89-9 60-57-1 72-20-8 72-54-8 72-55-9 76-44-8 789-02-6 959-98-8	- - -	628.00 €	Mon 21 Apr 25
Pesticide Mixture 200 100 µg/mL in Ethyl acetate REF: 04-GA09000200EACAS: 1024-57-3 1031-07-8 118-74-1 2385-85-5 27304-13-8 28044-83-9 309-00-2 319-84-6 319-85-7 319-86-8 33213-65-9 3424-82-6 50-29-3 5103-71-9 5103-74-2 53-19-0 58-89-9 60-57-1 72-20-8 72-43-5 72-54-8 72-55-9 76-44-8 789-02-6 82-68-8 959-98-8	- - -	548.00 €	Mon 21 Apr 25
Mitotane REF: AC-10985CAS: 53-19-0	- - -	To inquire	Mon 21 Apr 25
2,4'-DDD REF: 04-C12030000CAS: 53-19-0	- - -	76.00 €	Mon 21 Apr 25
Pesticide-Mix 164 10 µg/mL in Cyclohexane REF: 04-L18000164CYCAS: 3424-82-6 50-29-3 53-19-0 72-54-8 72-55-9 789-02-6	- - -	203.00 €	Mon 21 Apr 25
Pesticide-Mix 20 10 µg/mL in Cyclohexane REF: 04-LA18000020CYCAS: 1024-57-3 118-74-1 297-78-9 309-00-2 319-84-6 319-85-7 33213-65-9 3424-82-6 465-73-6 50-29-3 53-19-0 58-89-9 60-57-1 72-20-8 72-54-8 72-55-9 76-44-8 789-02-6 959-98-8	- - -	141.00 €	Mon 21 Apr 25
HJ 921-2017 Organochlorine Pesticides Mixture 109 100 µg/mL in Toluene:n-Hexane REF: 04-A50000109THCAS: 1024-57-3 118-74-1 2385-85-5 28044-83-9 319-84-6 319-85-7 319-86-8 33213-65-9 3424-82-6 39765-80-5 50-29-3 5103-71-9 5103-73-1 5103-74-2 53-19-0 58-89-9 60-57-1 72-20-8 72-54-8 72-55-9 789-02-6 959-98-8	- - -	To inquire	Mon 21 Apr 25
Pesticide Mix 5 10 µg/mL in Cyclohexane REF: 04-L18000005CYCAS: 3424-82-6 50-29-3 53-19-0 60-57-1 72-20-8 72-54-8 72-55-9 789-02-6	- - -	220.00 €	Mon 21 Apr 25
Pesticide-Mix 13 10 µg/mL in Cyclohexane REF: 04-LA18000013CYCAS: 1024-57-3 118-74-1 2385-85-5 27304-13-8 28044-83-9 309-00-2 319-84-6 319-85-7 319-86-8 33213-65-9 3424-82-6 35065-27-1 35065-28-2 35065-29-3 35693-99-3 37680-73-2 465-73-6 50-29-3 5103-71-9 5103-74-2 53-19-0 58-89-9 60-57-1 6108-10-7 7012-37-5 72-20-8 72-43-5 72-54-8 72-55-9 76-44-8 789-02-6 959-98-8	- - -	To inquire	Mon 21 Apr 25
Mitotane REF: 3B-M3304CAS: 53-19-0	>98.0%(GC)	55.00 €~163.00 €	Mon 21 Apr 25
Pesticide-Mix 13 10 µg/mL in Toluene REF: 04-LA18000013TOCAS: 1024-57-3 118-74-1 2385-85-5 27304-13-8 28044-83-9 309-00-2 319-84-6 319-85-7 319-86-8 33213-65-9 3424-82-6 35065-27-1 35065-28-2 35065-29-3 35693-99-3 37680-73-2 465-73-6 50-29-3 5103-71-9 5103-74-2 53-19-0 58-89-9 60-57-1 6108-10-7 7012-37-5 72-20-8 72-43-5 72-54-8 72-55-9 76-44-8 789-02-6 959-98-8	- - -	335.00 €	Mon 21 Apr 25
Pesticide-Mix 71 10 µg/mL in Cyclohexane REF: 04-L18000071CYCAS: 1024-57-3 117-18-0 118-74-1 28044-83-9 309-00-2 319-84-6 319-85-7 33213-65-9 3424-82-6 50-29-3 5103-71-9 5103-74-2 53-19-0 58-89-9 60-57-1 72-20-8 72-43-5 72-54-8 72-55-9 76-44-8 789-02-6 82-68-8 959-98-8	- - -	787.00 €	Mon 21 Apr 25
2,4'-DDD 10 µg/mL in Cyclohexane REF: 04-L12030000CYCAS: 53-19-0	- - -	55.00 €	Mon 21 Apr 25
2,4'-DDD 100 µg/mL in Cyclohexane REF: 04-XA12030000CYCAS: 53-19-0	- - -	54.00 €	Mon 21 Apr 25
Organochlorine Pesticides Mixture 637 500 µg/mL in Hexane REF: 04-A50000637HECAS: 1024-57-3 118-74-1 2385-85-5 309-00-2 319-84-6 319-85-7 319-86-8 33213-65-9 3424-82-6 465-73-6 50-29-3 53-19-0 58-89-9 60-57-1 72-20-8 72-43-5 72-54-8 72-55-9 76-44-8 789-02-6 959-98-8	- - -	To inquire	Mon 21 Apr 25
Mitotane-d4 REF: 4Z-M-091001CAS: 53-19-0	- - -	To inquire	Tue 22 Apr 25
Mitotane REF: 4Z-M-091002CAS: 53-19-0	- - -	To inquire	Tue 22 Apr 25
Mitotane REF: TR-M372500CAS: 53-19-0	- - -	101.00 €~706.00 €	Fri 25 Apr 25
Mitotane - Bio-X ™ REF: 3D-BM300096CAS: 53-19-0	Min. 95%	147.00 €	Mon 28 Apr 25
Mitotane REF: 3D-FM02907CAS: 53-19-0	Min. 98 Area-%	143.00 €~1,326.00 €	Mon 28 Apr 25