Fluorogenic Substrates
In this category, you will find a comprehensive selection of fluorogenic substrates designed for enzymatic catalysis. These substrates are used with various types of enzymes and are capable of producing color and fluorescence upon reaction. Fluorogenic substrates are essential tools in biochemical and molecular biology research, enabling the detection and quantification of enzyme activity with high sensitivity and specificity. They are widely used in assays for studying enzyme kinetics, screening for enzyme inhibitors, and monitoring cellular processes. At CymitQuimica, we provide high-quality fluorogenic substrates to support your research, ensuring reliable and accurate results in your enzymatic assays.
Found 284 products for "Fluorogenic Substrates".
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L-Lysyl-L-alanine 7-amido-4-methylcoumarin dihydrochloride
CAS:L-Lysyl-L-alanine 7-amido-4-methylcoumarin dihydrochloride is a fluorogenic peptide substrate for aminopeptidase. This AMC peptide substrate is normally used to rapidly profile the N-terminal specificity of proteases.Purity:Min. 98.0 Area-%Color and Shape:Powder4-Methylumbelliferyl 2-deoxy-2-sulfamino-b-D-glucopyranoside sodium salt
4-Methylumbelliferyl 2-deoxy-2-sulfamino-beta-D-glucopyranoside sodium salt is a fluorogenic substrate for N-sulfoglucosamine sulfohydrolase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl 2-deoxy-2-sulfamino-beta-D-glucopyranoside sodium saltas a substrate for measuring the N-sulfoglucosamine sulfohydrolase activity is used for screening of Mucopolysaccharidosis IIIA (MPS IIIA) and diagnosis of Sanfilippo A syndrome.Formula:C16H19NO10SNaPurity:Min. 95%Color and Shape:PowderMolecular weight:439.37 g/mol4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-glucopyranoside-6-sulfate potassium
CAS:4-Methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside-6-sulfate potassium is a fluorogenic substrate for N-acetylglucosamine-6-sulfatase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside-6-sulfate potassiumas a substrate for measuring the N-acetylglucosamine-6-sulfatase activity is used for screening of Mucopolysaccharidosis IIID (MPS IIID) (a rare lysosomal storage disorder) and Sanfilippo D syndrome diagnosis.Formula:C18H20KNO11SPurity:Min. 95%Color and Shape:White PowderMolecular weight:497.52 g/mol5-Dodecanoylaminofluorescein di-b-D-galactopyranoside
CAS:5-Dodecanoylaminofluorescein di-b-D-galactopyranoside, commonly known as C12FDG, is a fluorogenic substrate for β-galactosidase. Fluorescein is released upon enzymatic cleavage by β-galactosidase. The intensity of its fluorescence is utilised to quantify β-galactosidase activity. C12FDG has been shown to be useful in identifying senescent cells that are associated with aging and cancer. It has also been used as a model system in some studies for studying disease activity, intracellular targets, and biological sample storage. It is also used to identify cancer tissues and radiation damage in the form of senescent cells. The chemical structure of 5DAFG is similar to that of the natural sugar galactose. 5DAFG binds to the plasma membrane of cells due to its lipophilic properties and then enters the cell through transport proteins on the cell surface called ATP binding cassette transporters.Formula:C44H55NO16Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:853.9 g/molFluorescein di-beta-D-galactopyranoside
CAS:Fluorogenic substrate for beta-galactosidase
Formula:C32H32O15Purity:Min. 98 Area-%Color and Shape:Slightly Yellow PowderMolecular weight:656.59 g/mol4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside-6-sulfate sodium salt
CAS:4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt is a high-quality fluorogenic substrate specifically designed for the detection and quantification of various enzymes, including beta-glucosidases and sulfatases. Upon hydrolysis by the target enzyme, this substrate releases the highly fluorescent 4-methylumbelliferone, allowing for real-time monitoring and accurate measurement of enzyme activities in biochemical assays, diagnostic tests, and research applications. 4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt has excellent solubility in water, ensuring a consistent and reliable performance in different experimental conditions. This versatile substrate is an essential tool for researchers and industry professionals who require a sensitive and reproducible detection method for enzymes of interest.Formula:C18H20NO11SNaPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:481.41 g/mol4-Methylumbelliferyl a-L-fucopyranoside
CAS:Fluorogenic substrate for fucosidaseFormula:C16H18O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:322.31 g/mol4-Methylumbelliferyl a-L-arabinofuranoside
CAS:Fluorogenic substrate for ?-arabinofuranosidase
Formula:C15H16O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:308.28 g/mol6-Chloro-4-(trifluoromethyl)umbelliferyl β-D-cellotrioside
6-Chloro-4-(trifluoromethyl)umbelliferyl b-D-cellotrioside is a fluorogenic substrate for cellulases and beta-glucosidases. After hydrolisis, the fluorophore TFMU is released generating a blue fluorescence.Formula:C28H34ClF3O18Purity:Min. 95%Color and Shape:White to off-white powder.Molecular weight:751.01 g/mol4-Methylumbelliferyl heptanoate
CAS:Lipase targeting MOSCERDAM® substrateFormula:C17H20O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:288.34 g/mol4-Methylumbelliferyl b-D-ribofuranoside
CAS:The 4-Methylumbelliferyl b-D-ribofuranoside is a top-notch fluorogenic substrate for glycosidase activity detection. Upon hydrolysis by enzymes, it generates a strongly fluorescent 4-methylumbelliferone molecule, enabling rapid assay results and real-time monitoring of enzymatic reactions. This product is suitable for many biological research applications, such as in vitro analysis, diagnostic testing, and drug discovery. With its high sensitivity and specificity, it delivers consistent and accurate results, making it an essential tool for scientists and researchers.Formula:C15H16O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:308.28 g/mol4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside
CAS:Fluorogenic substrate for chitinaseFormula:C18H21NO8Purity:Min. 99 Area-%Color and Shape:White Off-White PowderMolecular weight:379.36 g/mol4-Methylumbelliferyl phosphate, free acid
CAS:A sensitive fluorogenic substrate for fluorometric and UV-spectrophotometric assays of phosphatases. It is used for the detection of C. perfringens because acid phosphatase is a highly specific indicator for C. perfringens.
Formula:C10H9O6PMolecular weight:256.15 g/mol4-Methylumbelliferyl N,N',N''-triacetyl-b-D-chitotrioside
CAS:4-Methylumbelliferyl N,N',N''-triacetyl-beta-D-chitotrioside is a fluorogenic substrate for chitinase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl N,N',N''-triacetyl-beta-D-chitotriosideas a substrate for measuring the chitinase activity is used for fungal infection assays.Formula:C34H47N3O18Purity:Min. 95.0 Area-%Color and Shape:White Off-White PowderMolecular weight:785.75 g/mol4-Trifluoromethylumbelliferyl β-D-galactopyranoside
CAS:4-Trifluoromethylumbelliferyl β-D-galactopyranoside is a fluorogenic substrate for beta-galactosidase . Upon hydrolysis, the fluorogenic moiety (blueish) 4-trifluoromethylumbelliferone (also known as TFMU) is released. 4-Trifluoromethylumbelliferyl β-D-galactopyranoside is commonly used in bacterial detection and in LacZ gene expression assays.
Formula:C16H15F3O8Purity:Min. 95%Color and Shape:PowderMolecular weight:392.28 g/molGlutaryl-glycyl-L-arginine 7-amido-4-methylcoumarin hydrochloride
CAS:Glutaryl-glycyl-L-arginine 7-amido-4-methylcoumarin hydrochloride is a synthetic peptide substrate used as a fluorogenic substrate for aminopeptidase.
Formula:C23H30N6O7·HClPurity:Min. 95%Color and Shape:PowderMolecular weight:538.98 g/mol4-Methylumbelliferyl-2-O-(α-L-fucopyranosyl)-β-L-fucopyranoside
4-Methylumbelliferyl-2-O-(alpha-L-fucopyranosyl)-beta-L-fucopyranoside is a fluorogenic substrate for alpha-L-fucosidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl-2-O-(alpha-L-fucopyranosyl)-beta-L-fucopyranosideas a substrate for measuring the alpha-L-fucosidase activity is used for diagnosis of fucosidosis (defficiency of L-fucosidase).Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:468.45 g/mol4-Methylumbelliferyl acetate
CAS:Fluorogenic substrate for carboxylesteraseFormula:C12H10O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:218.21 g/mol4-Methylumbelliferyl b-D-glucuronide trihydrate
CAS:Fluorogenic substrate for beta-glucuronidase GUS
Formula:C16H22O12Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:406.34 g/mol4-Methylumbelliferyl butyrate
CAS:Methylumbelliferyl butyrate is structurally based on 4-methylumbelliferone and is a MOSCERDAM® substrate. It targets the esterase enzyme.
Formula:C14H14O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:246.26 g/mol
