Inhibitor Enzymes
Inhibitor enzymes are molecules that decrease or block the activity of enzymes, preventing them from catalyzing their specific reactions. These inhibitors can be reversible or irreversible and are crucial tools in research and drug development for studying enzyme mechanisms, controlling metabolic pathways, and developing therapeutic agents. Inhibitor enzymes are widely used to modulate biological processes and to treat various diseases by targeting specific enzymes. At CymitQuimica, we offer a comprehensive range of high-quality enzyme inhibitors to support your research and pharmaceutical development needs.
Found 123 products of "Inhibitor Enzymes"
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3'-Deoxyadenosine 5’-Diphosphate Triethylamine Salt (>90%)
CAS:<p>Stability Hygroscopic<br>Applications 3'-Deoxyadenosine 5’-Diphosphate Triethylamine Salt, is a nucleotide and was proposed to be a possible inhibitor of DNA synthesis.<br>References Frederiksen, Sune.: Biochimica et Biophysica Acta, 76(3), 366-71 (1963)<br></p>Formula:C10H15N5O9P2•xC6H15NPurity:>90%Color and Shape:NeatMolecular weight:411.20 + x(101.19)Bis(2-butoxyethyl) 2-(3-Hydroxybutoxy)ethyl Phosphate Triester
CAS:Controlled Product<p>Applications Bis(2-butoxyethyl) 2-(3-Hydroxybutoxy)ethyl Phosphate Triester is derived from 2-Butoxyethanol (B692895), which is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors.<br>References Sun, Y., et al.: Bioorg. Med. Chem. Lett., 21, 3798 (2011); Yi, W., et al.: Eur. J. Med. Chem., 45, 639 (2010)<br></p>Formula:C18H39O8PColor and Shape:Colourless To Light YellowMolecular weight:414.47Nicotelline
CAS:Controlled Product<p>Applications Nicotelline is a Nicotine (N412420) related metabolite with potential as an inhibitor of human cytochrome P-450 2A6.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Denton, T. et al.: Biochem. Pharm., 67, 751 (2004); Gorrod, J. et al.: Anal. Det. Nic. Rel. Comp. Metab., 69, (1999);<br></p>Formula:C15H11N3Color and Shape:NeatMolecular weight:233.27Naringenin chalcone
CAS:Controlled ProductFormula:C15H12O5Color and Shape:NeatMolecular weight:272.25N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide Hydrochloride
CAS:Controlled Product<p>Applications Naphthalenesulfonamides derivatives are neoplasm inhibitors.<br>References Hidaka, H., et al.: Proc. Nat. Acad. Sci. USA, 78, 4354 (1981)<br></p>Formula:C20H29ClN2O2S·ClHColor and Shape:NeatMolecular weight:433.44Avelestat
CAS:Controlled Product<p>Applications Avelstat inhibits plasma neutrophil elastase (NE) activity in zymosan-stimulated whole blood, and also inhibits NE activity on the surface of stimulated polymorphonuclear cells and in the supernatant of primed, stimulated cells.<br>References Stevens, T., et al.: J. Pharmacol. Exp. Ther., 339, 313 (2011)<br></p>Formula:C25H22F3N5O4SColor and Shape:NeatMolecular weight:545.53Enviroxime
CAS:Controlled Product<p>Applications Enviroxime is a benzimidazole derivative that inhibits rhinovirus multiplication.<br>References De Long, D.C., et al.: J. Infect. Dis., 141, 87 (1980), Wikel, J.H., et al.: J. Med. Chem., 23, 368 (1980), Phillpotts, R.J., et al.: Lancet, 1, 1342 (1981), Haden, F.G., et al.: Antimicrob. Agents Chemother., 21, 892 (1982),<br></p>Formula:C17H18N4O3SColor and Shape:NeatMolecular weight:358.41Benzyl Methyl Carbonate
CAS:Controlled Product<p>Applications Benzyl Methyl Carbonate is used in designing of inhibitors for serine and thiol proteases.<br></p>Formula:C9H10O3Color and Shape:NeatMolecular weight:166.174,5,6,7-Tetrabromo-1H-benzotriazole
CAS:Controlled Product<p>Applications TBB is one of the most selective protein kinase inhibitors known, and when tested against a panel of 33 serine/threonine and tyrosine protein kinases, only three exhibited moderate inhibition by TBB, with Ki values one to two orders of magnitude higher than that for CK2.<br>References Boehning, D., et al.: Neuron, 40, 129 (2993)<br></p>Formula:C6HBr4N3Color and Shape:NeatMolecular weight:434.71Chelerythrine Chloride
CAS:<p>Stability Hygroscopic<br>Applications Chelerythrine Chloride is a cell permeable protein kinase C (PKC) inhibitor.<br>References Song, L., et. al.: Brain Res., 1564, 52 (2014)<br></p>Formula:C21H18NO4·ClColor and Shape:YellowMolecular weight:383.82(R)-Pinocembrin
CAS:Controlled Product<p>Applications (2R)-Pinocembrin is the (R)-enantiomer of Pinocembrin, a flavanoid with antioxidant activity found in damiana, honey, and propolis. (2R)-Pinocembrin is a potential inhibitor of PIM1 kinase, an oncogene that has been implicated in the development of leukemias, lymphomas, and prostate cancer.<br>References Zhao, J. et al.: J. Ethnopharmacol., 120, 387 (2008); Holder, S. et al.: Mol. Cancer Ther., 6, 163 (2007); Holder, S. et al.: Bioorg. Med. Chem., 15, 6463 (2007);<br></p>Formula:C15H12O4Color and Shape:WhiteMolecular weight:256.25O,O-Dimethyl Dithiophosphate
CAS:Controlled ProductFormula:C2H7O2PS2Color and Shape:ColourlessMolecular weight:158.18Morusin
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications Morusin is an inhibitor of human cervical cancer stem cell growth, attenuating NF-kB activity, and initiating apoptosis.<br>References Wang, L. et al.: Mol. Cell. Biochem., 379, 7 (2013);<br></p>Formula:C25H24O6Color and Shape:NeatMolecular weight:420.45GDC 0152
CAS:Controlled Product<p>Applications GDC 0152 is a peptidomimetic small molecule antagonist of inhibitor of apoptosis (IAP) proteins with antitumor activity.<br>References Yue, Q., et. al.: Drug Metab. Dispos., 41, 508 (2013)<br></p>Formula:C25H34N6O3SColor and Shape:NeatMolecular weight:498.64Ipidacrine Hydrochloride Hydrate
CAS:Formula:C12H16N2·ClH·H2OColor and Shape:NeatMolecular weight:242.753a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol, can be used in the synthesis of Hexosaminidase inhibitors, which are the new drug candidates for the therapy of osteoarthritis.<br>References Liu, J. et al.: Chem. Bio., 8, 701 (2001);<br></p>Formula:C8H13NO4SColor and Shape:White To Light BeigeMolecular weight:219.26Bisindolylmaleimide VIII Acetic Acid Salt
CAS:Controlled Product<p>Applications It is a potent inhibitor of protein kinase C (PKC) activity. Bisindolylmaleimide VIII (Bis VIII) has been previously shown to enhance Fas-mediated apoptosis through a protein kinase C-independent mechanism.<br>References Emery, J., et al.: J. Biol. Chem., 273, 14363 (1998), Wiley, S., et al.: Immunity, 3, 673 (1995), MacFarlane, M., et al.: Biochem. J., 348, 93 (2000),<br></p>Formula:C26H26N4O4Color and Shape:NeatMolecular weight:458.511-(5-Isoquinolinesulfonyl)-2-methylpiperazine Dihydrochloride
CAS:Controlled Product<p>Applications A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases.<br>References Hidaka, H. and Kawamoto, S.: Biochem. and Biophys. Res. Comm., 125, 1, 258 (1984)<br></p>Formula:C14H17N3O2S·2ClHColor and Shape:NeatMolecular weight:364.29O,S-Diethyl Methylphosphonothioate
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications An inhibitor of cholinesterase.<br>References Berman, H., et al.: J. Biol. Chem., 264, 3951 (1989), Millard, C., et al.: Biochemistry, 37, 237 (1998), Koellner, G., et al.: J. Mol. Biol., 296, 713 (2000),<br></p>Formula:C5H13O2PSColor and Shape:NeatMolecular weight:168.193-Acetyl-11-keto-β-boswellic Acid
CAS:Controlled ProductFormula:C32H48O5Color and Shape:WhiteMolecular weight:512.721-Propan-1,1,2,2,3,3,3-d7-amine
CAS:Controlled ProductFormula:C3H2D7NColor and Shape:NeatMolecular weight:66.15O-(2,4-Dinitrophenyl)hydroxylamine
CAS:<p>Applications O-(2,4-Dinitrophenyl)hydroxylamine is a rapid active-site-directed inhibitor of D-amino acid oxidase; modification results in specific incorporation of an amine group into an accessible nucleophilic residue with concomitant release of 2,4-dinitrophenol.<br>References D'Silva, C., et al.: Biochemi., 25, 5602 (1986),<br></p>Formula:C6H5N3O5Color and Shape:Brown SolidMolecular weight:199.12N-Acetyl-Lys-Octreotide Trifluoroacetic Acid Salt
CAS:<p>Stability Hygroscopic<br>Applications N-Acetyl-Phe-Octreotide is used as reactant/reagent in inhibition of octreotide acylation inside PLGA microspheres by derivatization of amines of peptide with self-immolative protecting group.<br>References Shirangi, M., et al.: Bioconjugate Chem., 27, 576-585 (2016)<br></p>Formula:C51H68N10O11S2·xC2HF3O2Color and Shape:NeatMolecular weight:1061.284Resolvin E1 Sodium Salt
CAS:Controlled ProductFormula:C20H29NaO5Color and Shape:NeatMolecular weight:372.431(5E)-6-(4-Hydroxy-3-methoxyphenyl)-5-hexene-2,4-dione
CAS:Controlled Product<p>Applications Curcumin (C838500) and gingerdione derivative. A possible human glyoxalase I inhibitor. Flavor modifier.<br>References Yuan, M. et al.; Bioorg. Med. Chem. 19, 1189 (2011); Ley, J. et al.; J. Agr. Food Chem. 56, 6656 (2008)<br></p>Formula:C13H14O4Color and Shape:NeatMolecular weight:234.25(±)-Procinolol Hydrochloride
CAS:Controlled Product<p>Applications (±)-Procinolol is a beta adrenergic receptor antagonist.<br>References Singh, K.: Indian J. Phsiol. Pharmacol., 27, 311 (1983)<br></p>Formula:C15H24ClNO2Color and Shape:NeatMolecular weight:285.81Baohuoside I
CAS:Controlled Product<p>Applications Baohuoside I is an inhibitor of cell growth and also is a down-regulator of durvivin and cyclin D1 expression. Used in the treatment of esophageal cancer. Anti-cancer agent.<br>References Lifang, W. et al.: Oncology Rep., 26, 1149 (2011); Jin, X. et al.: Drug Dev. Ind. Pharm., 39, 1421 (2013);<br></p>Formula:C27H30O10Color and Shape:NeatMolecular weight:514.52Raloxifene 4’-β-D-Glucuronide Lithium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Raloxifene 4’-Glucuronide Lithium Salt is a metabolite of Raloxifene (R099995), a nonsteroidal estrogen receptor mixed agonist/antagonist.<br>References Dodge, J., et al.: Bioorg. Med. Chem. Lett., 7, 993 (1997); Jeong, E., et al.: Drug Metab. Dispos., 33, 785 (2005); Trontelj, J., et al.: Pharmacol. Res., 52, 334 (2005); Oswald, S., et al.: Clin. Pharmacol. Ther., 79 206 (2006)<br></p>Formula:C34H34LiNO10SColor and Shape:NeatMolecular weight:655.644-Amino-5-(bromomethyl)-2-methylpyrimidine Dihydrobromide
CAS:Controlled Product<p>Applications A pyrimidine derivative as G protein-coupled receptor kinase (GRK) inhibitor.<br>References Bigham, E., et al.: J. Med. Chem., 35, 1399 (1992), Jansen, M., et al.: Biochem. Pharmacol., 47, 1067 (1994), Hasbi, A., et al.: J. Neurochem., 70, 2129 (1998),<br></p>Formula:C17H17N3O2SColor and Shape:NeatMolecular weight:327.40N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride
CAS:Controlled Product<p>Applications Found to have a potent inhibitory action against casein kinase 1 completely with respect to ATP and a much weaker effect on casein kinase 2 and other protein kinases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hidaka, H., et al.: J. of Biol. Chem., 264, 9, 4924 (1989)<br></p>Formula:C11H12ClN3O2S·2ClHColor and Shape:NeatMolecular weight:358.67Retorphan
CAS:Controlled Product<p>Applications Retorphan is a powerful and selective inhibitors of neprilysin and is being developed as a therapeutic agent. Retorphan behave as the prodrug of the enantiomers of Thiorphan (T369500).<br>References Monteil, T., et al.: Mini. Rev. Med. Chem., 2, 209 (2002); Roques, B.P., et al.: Nature, 288, 286 (1980); Tiraboschi, G., et al.: Protein Engineering, 12, 2, 141 (1999)<br></p>Formula:C21H23NO4SColor and Shape:NeatMolecular weight:385.48(1R,2R)-2-Fluorocyclopentanamine Hydrochloride
CAS:Controlled Product<p>Applications A cyclopentanamine used in the preparation of heterocyclic and aromatic ureas and amides as CEPT inhibitors.<br></p>Formula:C5H11ClFNColor and Shape:NeatMolecular weight:139.61-Deoxy-L-altronojirimycin Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications α-Glycosidase inhibitor.<br>References Jefferies, I., et al.: Bioorg. Med. Chem. Lett., 7, 1171 (1997), Hassan, A., et al.: Carbohydr. Res., 339, 1565 (2004),<br></p>Formula:C6H13NO4·ClHPurity:>90%Color and Shape:NeatMolecular weight:199.634-Fluorobenzoic Acid-d4
CAS:Controlled Product<p>Applications 4-Fluorobenzoic Acid-d4 is used as a reagent in the synthesis of Flurofamide-d4 (F596687); the isotope labelled analog of Fluorofamide (F596685) which is a compound that acts as a urease inhibitor, useful in the treatment of gastritis and irregular urease activity in the urinary tract.<br>References Loes, A. et al.: Lett. App. Microbiol., 58, 31 (2014); Ohta, T.et al.: Biochem. Biophys, Res. Comm., 285, 728 (2001)<br></p>Formula:C7HD4FO2Color and Shape:NeatMolecular weight:144.14tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)carbamate
CAS:Controlled ProductFormula:C17H30BNO4Color and Shape:NeatMolecular weight:323.24n-Pentyl-d11 chloroformate
CAS:Controlled Product<p>Applications n-Pentyl-d11 chloroformate is labelled n-Pentyl chloroformate which can be used to synthesize 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase.<br>References Kim, I., et al.: J. Med. Chem., 47, 2110 (2004); Hammock, B., et al.: PCT Int. Appl. (2006), WO 2006045119 A2 20060427.<br></p>Formula:C6D11ClO2Color and Shape:NeatMolecular weight:161.674-Pyridin-2,3,5,6-d4-ol-d
CAS:Controlled Product<p>Applications 4-Pyridin-2,3,5,6-d4-ol-d is one of the azepanone derivatives studies as CGRP receptor antagonists.<br>References Liu, J.: PCT Int. Appl. (2010), WO 2010108103 A1 20100923.<br></p>Formula:C5D5NOColor and Shape:NeatMolecular weight:100.13n-Propyl-2,2,3,3,3-d5-amine Hydrochloride
CAS:Controlled Product<p>Applications n-Propyl-2,2,3,3,3-d5-amine Hydrochloride is the hydrochloride salt of 1-Propyl-d5-amine (P833702); the isotope labelled analog of 1-Propylamine (P833700) which is used in the synthesis of pyrimidine derivatives as novel and highly potent PDE4 inhibitors. It is also used in the preparation of fluorenone analogs with DNA topisomerase I inhibitors.<br>References Goto, T. et al.: Bioorg. Med. Chem., 21, 7025 (2013); Lee, C. et al.: Bioorg. Med. Chem. 21, 7125, (2013)<br></p>Formula:C3H5D5ClNColor and Shape:NeatMolecular weight:100.6tert-Butyl 4-Bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
CAS:Controlled ProductFormula:C18H17BrN2O3Color and Shape:NeatMolecular weight:389.24GW4869 TFA Salt (~90%, ~10% inorganics)
CAS:Controlled Product<p>Applications GW4869 is a selective inhibitor of N-SMase.<br>References Lallemand, T., et al.: Arterioscler. Thromb. Vasc. Biol., 38, 1479 (2018); Figuera-Losada, M., et al.: PLoS One, 10, 0124481 (2015)<br></p>Formula:C30H28N6O2·xC2HF3O2Color and Shape:NeatMolecular weight:504.58 + x(114.02)N-Fmoc-glycine-d2
CAS:Controlled Product<p>Applications Isotope labelled N-Fmoc-glycine is an N-Fmoc-protected form of Glycine (G615990). Glycine is a nonessential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective against oxidant damage in the kidney.<br>References Eulenberg, V., et al.: Trend. Biochem. Sci., 30, 325 (2005); Gundersen, R., et al.: Acta Anaesth. Scand., 49, 1108 (2005); Lockart, R. & Eagle, H.: Science, 129, 252 (1959); Sogabe, K., et al.: Kidn. Int., 50, 845 (1996)<br></p>Formula:C17H13D2NO4Color and Shape:NeatMolecular weight:299.32Ethyl Palmitate-d31
CAS:Controlled Product<p>Applications A labelled fatty acid found in Amaranth oil; it shows inhibitory activity.<br>References Fidler, N., et al.: J. Lipid Res., 41, 1376 (2000), Yang, T., et al.: Food Chem., 80, 473 (2003), Gamel, T., et al.: J. Food Lipids, 14, 323 (2007),<br></p>Formula:C18H5D31O2Color and Shape:NeatMolecular weight:315.671-Propyl-d5-amine
CAS:Controlled Product<p>Applications 1-Propyl-d5-amine is labelled 1-Propylamine (P833700) which is used in the synthesis of pyrimidine derivatives as novel and highly potent PDE4 inhibitors. It is also used in the preparation of fluorenone analogs with DNA topisomerase I inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C3H4D5NColor and Shape:NeatMolecular weight:64.14(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (3R,5S,6E)-7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent.<br>References Suzukim M., et al.: Bioorg. Med. Chem., 9, 2977 (1999); Yen, H., et al.: J. Clin. Invest., 98, 1253 (1996); Zou, Y., et al.: J. Biol. Chem., 274, 9760 (1999); Sun, X., et al.: Cancer Res., et al.: 61, 3382 (2001); Ladas, E.J., et al.: Clin. Oncol., 22, 517 (2004);<br></p>Formula:C25H24NNaO4Color and Shape:NeatMolecular weight:425.45rac-1,2-Dioctanoyl-3-Chloropropanediol
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications rac-1,2-Dioctanoyl-3-Chloropropanediol was studied for its ability to act as an inhibitor of protein kinase C.<br>References Briggs, Josie C., et al.: Carbohydrate Res., 234, 23-35 (1992)<br></p>Formula:C19H35ClO4Color and Shape:NeatMolecular weight:362.93N-(n-Butyl)phosphoric Triamide
CAS:<p>Applications N-Alkyl phosphoric triamide useful as urease inhibitors.<br></p>Formula:C4H14N3OPColor and Shape:White SolidMolecular weight:151.153-Amino-N-(Tertbutylbenzenesulfonamide
CAS:Controlled Product<p>Applications 3-Amino-N-(Tert-Butyl)Benzenesulfonamide (cas# 608523-94-0) is a useful research chemical.<br></p>Formula:C10H16N2O2SColor and Shape:NeatMolecular weight:228.31(E)-a-Hydroxy Tamoxifen
CAS:Controlled Product<p>Applications A metabolite of the chemotherapeutic drug Tamoxifen (T006000). Exhibits a more potent estrogen agonist/antagonist activity than the parent drug. Also active as an intramembranous inhibitor of lipid peroxidation.<br>References Kupfer, D., et al.: Cancer Res., 54, 3140 (1994), Custodio, J.B.A., et al.: Biochem. Pharmacol., 47, 1989 (1994),<br></p>Formula:C26H29NO2Color and Shape:NeatMolecular weight:387.51Valtrate
CAS:Controlled Product<p>Applications Valtrate is a Rev-transport inhibitor with anti-HIV activity from Valerianae Radix.<br>References Murakami, N., et al.: Bioorg. Med. Chem. Lett., 12, 2807 (2002); Watanabe, K., et al.: Drug Discoveries Ther., 5, 26 92011)<br></p>Formula:C22H30O8Color and Shape:Light Brown To Dark YellowMolecular weight:422.47A 83-01
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications A 83-01 is a selective inhibitor of TGF-β type I receptor. A 83-01 treatment increases tumor permeability.<br>References Minowa, T. et al.: British. J. Canc., 101, 1884 (2009)<br></p>Formula:C25H19N5SColor and Shape:Off-WhiteMolecular weight:421.52
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![tert-Butyl 4-Bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB694160.webp&w=3840&q=75)
