Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(166 products)
- Bcr-Abl(117 products)
- EGFR(578 products)
- FAK(72 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(179 products)
- JAK(244 products)
- PDGFR(129 products)
- RAAS(89 products)
- Src(82 products)
- Syk(37 products)
- Thrombin(56 products)
- VDA(2 products)
- VEGFR(242 products)
Show 6 more subcategories
Found 2369 products of "Angiogenesis"
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Ponatinib-d8
CAS:Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).Formula:C29H27F3N6OPurity:98%Color and Shape:SolidMolecular weight:540.61GW2974
CAS:GW2974, Oral EGFR/ErbB2 dual inhibitor, inhibits glioblastoma multiforme (GBM) cell invasion and tumor growth.Formula:C23H21N7Color and Shape:SolidMolecular weight:395.46(3S,4S)-PF-06459988
CAS:(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.Formula:C19H22ClN7O3Color and Shape:SolidMolecular weight:431.88Nilotinib-d6
CAS:Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.Formula:C28H22F3N7OPurity:98%Color and Shape:SolidMolecular weight:535.55SU11652
CAS:SU11652 is an effective and competitive receptor tyrosine kinase (RTK) inhibitor, including VEGFR, FGFR, PDGFR, and Kit.Formula:C22H27ClN4O2Purity:99.14%Color and Shape:SolidMolecular weight:414.93FLT3-IN-16
CAS:FLT3-IN-16 is a potent FLT3 inhibitor (IC50 = 1.1 μM) for acute myeloid leukemia research.Formula:C15H15N3O2SPurity:99.21%Color and Shape:SolidMolecular weight:301.36Ref: TM-T9843
2mg34.00€5mg52.00€10mg86.00€25mg172.00€50mg260.00€100mg369.00€200mg487.00€1mL*10mM (DMSO)58.00€Tucatinib hemiethanolate
CAS:Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.Formula:C54H54N16O5Purity:99.76%Color and Shape:SolidMolecular weight:1007.11(E/Z)-Zotiraciclib hydrochloride
CAS:(E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent inhibitor of CDK2, JAK2, and FLT3.Formula:C23H25ClN4OColor and Shape:SolidMolecular weight:408.93DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formula:C26H35N7O5Color and Shape:SolidMolecular weight:525.6Atinvicitinib
CAS:Atinvicitinib, a selective JAK1 inhibitor, blocks cytokine signaling, modulating itch, allergy, and inflammatory responses, immune and therapeutic studies.Formula:C16H17FN6O3Purity:99.36%Color and Shape:SolidMolecular weight:360.35Ref: TM-T39646
1mg138.00€5mg334.00€10mg550.00€25mg1,063.00€50mg1,738.00€100mg2,547.00€1mL*10mM (DMSO)264.00€Flurandrenolide
CAS:Flurandrenolide is a corticosteroid with anti-inflammatory effects that activates EGFR (EC50=23 nM).Formula:C24H33FO6Color and Shape:Crystals From Acetone + Hexane SolidMolecular weight:436.51LDN-193189 Tetrahydrochloride
CAS:LDN193189 is a BMPI receptor inhibitor, blocking ALK2 and ALK3 effectively, while weak on ALK4, ALK5, ALK7.Formula:C25H26Cl4N6Purity:98.21%Color and Shape:SolidMolecular weight:552.33Asciminib hydrochloride
CAS:Asciminib hydrochloride is a STAMP inhibitor targeting the ABL myristoyl pocket, applied in Ph+ CML research for selective oncogenic signaling modulation.Formula:C20H19Cl2F2N5O3Purity:99.91%Color and Shape:SolidMolecular weight:486.3Ref: TM-T63226
1mg57.00€5mg130.00€10mg177.00€25mg289.00€50mg409.00€100mg620.00€1mL*10mM (DMSO)138.00€CHZ868
CAS:CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.Formula:C22H19F2N5O2Purity:99.38%Color and Shape:SolidMolecular weight:423.42A-770041
CAS:A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.Formula:C34H39N9O3Purity:99.23% - 99.86%Color and Shape:SolidMolecular weight:621.73Ref: TM-T14074
2mg70.00€5mg104.00€10mg170.00€25mg384.00€50mg652.00€100mg1,018.00€200mg1,350.00€1mL*10mM (DMSO)142.00€NX-5948
CAS:NX-5948 (BTK-IN-24) is a PROTAC-type BTK degrader with anti-inflammatory and anticancer activities, inhibiting B cell activation.Formula:C42H54N12O5Purity:98.29%Color and Shape:SolidMolecular weight:806.96Erlotinib-d6
CAS:Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .Formula:C22H23N3O4Purity:98%Color and Shape:SolidMolecular weight:399.47Aflibercept
CAS:Aflibercept has a wide range of applications in life science related research.Color and Shape:LiquidIlunocitinib
CAS:Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.Formula:C17H17N7O2SPurity:99.88%Color and Shape:SolidMolecular weight:383.43Ref: TM-T38571
1mg92.00€5mg230.00€10mg356.00€25mg713.00€50mg1,189.00€100mg1,791.00€200mg2,412.00€1mL*10mM (DMSO)251.00€Telatinib mesylate
CAS:Telatinib mesylate is a potent, orally active inhibitor of VEGFR2 (IC50: 6 nM), VEGFR3 (IC50: 4 nM), PDGFα (IC50: 15 nM) and c-Kit (IC50: 1 nM).Formula:C21H20ClN5O6SColor and Shape:SolidMolecular weight:505.93SM1-71
CAS:SM1-71 is a TAK1 inhibitor that inhibits MKNK2 and RSK2.SM1-71 acts as a kinase probe with anticancer activity.Formula:C24H26ClN7OPurity:96%Color and Shape:SolidMolecular weight:463.96BPR1K871
CAS:BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values ofFormula:C25H28ClN7O2SColor and Shape:SolidMolecular weight:526.05Pentagamavunon-1
CAS:PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.Formula:C23H24O3Color and Shape:SolidMolecular weight:348.43SM27
CAS:SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.Formula:C21H16N2O9S2Purity:98.83%Color and Shape:SolidMolecular weight:504.49Osimertinib dimesylate
CAS:Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).Formula:C30H41N7O8S2Purity:98%Color and Shape:SolidMolecular weight:691.82Lanraplenib succinate
CAS:Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Formula:C58H68N18O14Color and Shape:SolidMolecular weight:1241.294Cediranib maleate
CAS:Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.Formula:C29H31FN4O7Color and Shape:SolidMolecular weight:566.58Mavelertinib
CAS:Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.Formula:C18H22FN9O2Purity:99.89%Color and Shape:SolidMolecular weight:415.42Tetrac
CAS:Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blockingFormula:C14H8I4O4Purity:99.00%Color and Shape:SolidMolecular weight:747.83Neratinib maleate
CAS:Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.Formula:C34H33ClN6O7Purity:99.99%Color and Shape:SolidMolecular weight:673.11NSC 12
CAS:NSC 12 is an orally active pan-FGF trap that binds FGF2 and interferes with its interaction with FGFR1 with potential FGF-dependent antitumor activity.Formula:C24H34F6O3Purity:99.51%Color and Shape:SolidMolecular weight:484.52Pazopanib-d6
CAS:Pazopanib-d6 is a deuterated compound of Pazopanib.Formula:C21H17D6N7O2SColor and Shape:SolidMolecular weight:443.56Zanubrutinib-d5
Zanubrutinib-d5 (BGB-3111-d5) is a deuterium-labeled Zanubrutinib, an orally available Bruton's tyrosine kinase inhibitor for the study of B-cell malignancies.Formula:C27H29N5O3Purity:>99.99%Color and Shape:SolidMolecular weight:476.58Surfen dihydrochloride
CAS:Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a heparin sulfate antagonist with antimicrobial properties and inhibits blockade of signaling.Formula:C21H22Cl2N6OPurity:97.08%Color and Shape:SolidMolecular weight:445.35Bleximenib oxalate
CAS:Bleximenib oxalate (Menin-MLL inhibitor 24 oxalate) is a menin-MLL inhibitor that blocks the binding of the menin-KMT2A complex to chromatin at gene promoters.Formula:C34H52FN7O7Purity:98%Color and Shape:SolidMolecular weight:689.82(Z)-Orantinib
CAS:(Z)-Orantinib ((Z)-SU6668) is an orally active ATP-competitive inhibitor of Flk-1/KDR, PDGFRβ, and FGFR1, acting as a potent anti-angiogenic and anti-tumor agent.Formula:C18H18N2O3Purity:98.05%Color and Shape:SolidMolecular weight:310.35Brivanib
CAS:Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold againstFormula:C19H19FN4O3Purity:98.87%Color and Shape:SolidMolecular weight:370.38Ref: TM-T6036
1mg44.00€5mg94.00€10mg137.00€25mg245.00€50mg355.00€100mg530.00€200mg772.00€1mL*10mM (DMSO)92.00€Regorafenib-d3
CAS:Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.Formula:C21H15ClF4N4O3Purity:98%Color and Shape:SolidMolecular weight:485.83SB1317
CAS:SB1317 (TG02) is a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).Formula:C23H24N4OPurity:99.86%Color and Shape:SolidMolecular weight:372.46Ribociclib-d6
CAS:Ribociclib-d6 is a deuterated compound of Ribociclib (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.Formula:C23H30N8OColor and Shape:SolidMolecular weight:440.57Lck inhibitor 2
CAS:Lck inhibitor 2 blocks tyrosine kinases LCK, BTK, LYN, SYK, TXK with IC50s: Lck 13nM, Btk 9nM/26nM, Lyn 3nM, Txk 2nM.Formula:C18H17N5O2Color and Shape:SolidMolecular weight:335.36N-piperidine Ibrutinib hydrochloride
CAS:N-piperidine Ibrutinib hydrochloride is a BTK inhibitor that inhibits WT BTK and C481S BTK , which inhibits the growth and proliferation of cancer cells.Formula:C22H23ClN6OPurity:98.83%Color and Shape:SolidMolecular weight:422.91Iruplinalkib
CAS:Iruplinalkib (WX-0593) is an orally active, selective and potent ALK and ROS1 tyrosine kinase inhibitor with anticancer activity for use in the study of non-small cell lung cancer.Formula:C29H38ClN6O2PPurity:97.38% - 99.29%Color and Shape:SolidMolecular weight:569.08Poseltinib
CAS:Poseltinib is an oral, irreversible BTK inhibitor (IC50 1.95 nM) with higher selectivity over BMX, TEC, and TXK, blocking BCR, FcR, and TLR signaling.Formula:C26H26N6O3Purity:99.98%Color and Shape:SolidMolecular weight:470.52Ref: TM-T4413
2mg34.00€5mg49.00€10mg75.00€25mg146.00€50mg260.00€100mg409.00€200mg590.00€1mL*10mM (DMSO)50.00€Gefitinib-d8
CAS:Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.Formula:C22H24ClFN4O3Purity:98%Color and Shape:SolidMolecular weight:454.95Imatinib-d8
CAS:Imatinib-d8 (STI571 D8) is a 2H-labeled form of Imatinib. Imatinib is a multi-target receptor tyrosine kinase inhibitor with antitumor activity.Formula:C29H23D8N7OPurity:98%Color and Shape:SolidMolecular weight:501.65Momelotinib sulfate
CAS:Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.Formula:C23H26N6O10S2Purity:98%Color and Shape:SolidMolecular weight:610.62Rociletinib hydrobromide
CAS:Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).Formula:C27H29BrF3N7O3Purity:98%Color and Shape:SolidMolecular weight:636.46Elsubrutinib
CAS:Elsubrutinib (ABBV-105) is an orally active, selective, and irreversible BTK inhibitor with an IC50 of 0.18 μM for the catalytic domain of BTK.Formula:C17H19N3O2Purity:99.77%Color and Shape:SolidMolecular weight:297.36Ref: TM-T39130
1mg145.00€5mg250.00€10mg340.00€25mg573.00€50mg879.00€100mg1,314.00€1mL*10mM (DMSO)356.00€Rilematovir
CAS:Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.Formula:C21H20ClF3N4O3SPurity:99.95%Color and Shape:SolidMolecular weight:500.92
