Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(159 products)
- Bcr-Abl(115 products)
- EGFR(593 products)
- FAK(72 products)
- FLT(89 products)
- Fibroblast Growth Factor Receptor (FGFR)(182 products)
- JAK(246 products)
- PDGFR(126 products)
- RAAS(90 products)
- Src(81 products)
- Syk(37 products)
- Thrombin(53 products)
- VDA(2 products)
- VEGFR(247 products)
Show 6 more subcategories
Found 2121 products of "Angiogenesis"
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SU16f
CAS:SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.Formula:C24H22N2O3Purity:97.69%Color and Shape:SolidMolecular weight:386.44HIF-2α-IN-3
CAS:HIF-2α-IN-3 is an allosteric inhibitor of HIF-2α (IC50: 0.4 μM; KD: 1.1 μM) with anticancer activity.Formula:C12H6ClN5O5Purity:98.11%Color and Shape:SolidMolecular weight:335.66VEGFR-3-IN-1
CAS:VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.Formula:C29H29ClF3N7OSPurity:99.95%Color and Shape:SolidMolecular weight:616.1Defactinib hydrochloride
CAS:Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.Formula:C20H22ClF3N8O3SPurity:98.06% - 98.78%Color and Shape:SolidMolecular weight:546.95ARN25068
CAS:ARN25068 inhibits GSK-3β, FYN, DYRK1A kinases; acts in sub-micromolar range; combats tau hyperphosphorylation.Formula:C19H18N6SPurity:99.75%Color and Shape:SolidMolecular weight:362.45(R)-Zanubrutinib
CAS:(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).Formula:C27H29N5O3Purity:99.55%Color and Shape:SolidMolecular weight:471.55P505-15 Acetate
CAS:<p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>Formula:C21H27N9O3Purity:99.99%Color and Shape:SolidMolecular weight:453.5TP0427736 hydrochloride
CAS:TP0427736 hydrochloride is a novel and selective ALK5 inhibitor, capable of inhibiting Smad2/3 phosphorylation in A549 cells.Formula:C14H11ClN4S2Purity:98.99%Color and Shape:SolidMolecular weight:334.85NX-2127
CAS:NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferativeFormula:C39H45N9O5Purity:99.07%Color and Shape:SolidMolecular weight:719.83MBM-55
CAS:MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.Formula:C28H27FN6O2Purity:99.83%Color and Shape:SolidMolecular weight:498.55(E)-FeCP-oxindole
CAS:(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。Formula:C19H15FeNOPurity:99.85%Color and Shape:SolidMolecular weight:329.17EGFR-IN-99
CAS:EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor for the study of non-small cell lung cancer (NSCLC).Formula:C25H22FN7O3Purity:97.75%Color and Shape:SolidMolecular weight:487.49Sunvozertinib
CAS:Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor, with inhibitory effects on EGFR, Her2.Cost-effective and quality-assured.Formula:C29H35ClFN7O3Purity:98.11% - 99.63%Color and Shape:SolidMolecular weight:584.08(±)-Zanubrutinib
CAS:(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability,Formula:C27H29N5O3Purity:99.09%Color and Shape:SolidMolecular weight:471.55H-9 dihydrochloride
CAS:H-9 dihydrochloride: Strong PKA inhibitor, curbs 5-HT response and EGF signaling, affects pharyngeal function.Formula:C11H15Cl2N3O2SPurity:97.3%Color and Shape:SolidMolecular weight:324.23Tyrphostin A25
CAS:Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.Formula:C10H6N2O3Purity:98.98%Color and Shape:Yellow Green Powder /Off-White SolidMolecular weight:202.17WDR5-0102
CAS:<p>WDR5-0102 inhibits WDR5-MLL1 (Kd=4 μM), blocks MLL1 HMT activity, but doesn't affect SETD7 and 6 other HMTs.</p>Formula:C18H19ClN4O3Purity:98.03%Color and Shape:SolidMolecular weight:374.82PD 174265
CAS:PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.Formula:C17H15BrN4OPurity:99.51%Color and Shape:SolidMolecular weight:371.23MY10
CAS:MY10, a potent and orally active inhibitor of the receptor protein tyrosine phosphatase (RPTPβ/ζ), effectively reduces binge-like ethanol consumption andFormula:C15H10F6OS2Purity:98.64%Color and Shape:SolidMolecular weight:384.36Conteltinib
CAS:Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.Formula:C32H45N9O3SPurity:98.12% - 99.54%Color and Shape:SolidMolecular weight:635.82CGP77675
CAS:CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates andFormula:C26H29N5O2Purity:99.66%Color and Shape:SolidMolecular weight:443.54Epitinib succinate
CAS:Epitinib succinate (HMPL-813 succinate) is an orally active and brain penetration EGFR tyrosine kinase inhibitor and can be used in studies about cancer.Formula:C28H32N6O6Purity:98.02% - 99.79%Color and Shape:SolidMolecular weight:548.59Pimicotinib
CAS:Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.Formula:C22H24N6O3Purity:99.8%Color and Shape:SolidMolecular weight:420.46SI-2 hydrochloride
CAS:SI-2 hydrochloride, an SRC-3 inhibitor, induces breast cancer cell death (IC50: 3-20 nM) with good oral bioavailability.Formula:C15H16ClN5Purity:98.6%Color and Shape:SolidMolecular weight:301.77(Z)-FeCP-oxindole
CAS:(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.Formula:C19H15FeNOPurity:99.63% - 99.84%Color and Shape:SolidMolecular weight:329.17SRX3207
CAS:SRX3207 is an inhibitor of Syk and PI3K and relieves tumor immunosuppression.Formula:C29H29N7O3SPurity:99.85%Color and Shape:SolidMolecular weight:555.65SKLB 1028
CAS:SKLB 1028, an oral EGFR/FLT3/Abl inhibitor, excels in AML and CML with Abl mutations.Formula:C24H29N9Purity:99.99% - >99.99%Color and Shape:SolidMolecular weight:443.55Cloperastine fendizoate
CAS:Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).Formula:C40H38ClNO5Purity:99.97%Color and Shape:SolidMolecular weight:648.19A-935142
CAS:A-935142 enhances hERG (Kv 11.1) channels, slows inactivation, promotes activation, and shortens repolarization.Formula:C18H19F3N2O2Purity:98.97% - 99.91%Color and Shape:SolidMolecular weight:352.35EGFR-IN-9
CAS:EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M).Formula:C29H24N4O3Purity:99.8%Color and Shape:SolidMolecular weight:476.53Falnidamol
CAS:Falnidamol (BIBX 1382), an oral selective EGFR inhibitor, IC50 3 nM, weak on ErbB2 and others, anti-cancer pyrimido-pyrimidine.Formula:C18H19ClFN7Purity:98.816%Color and Shape:SolidMolecular weight:387.84Butyzamide
CAS:<p>Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.</p>Formula:C29H32Cl2N2O5SPurity:99.51% - 99.83%Color and Shape:SoildMolecular weight:591.55JNJ-49095397
CAS:<p>JNJ-49095397 (RV568) is a p38 MAPK-α and p38 MAPK-γ kinase inhibitor for the study of respiratory syncytial virus infection.</p>Formula:C34H36N6O4Purity:98.33% - 99.04%Color and Shape:SolidMolecular weight:592.69A 419259 trihydrochloride
CAS:A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).Formula:C29H37Cl3N6OPurity:99.75% - 99.96%Color and Shape:SolidMolecular weight:592Tilfrinib
CAS:Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities.Formula:C17H13N3OPurity:99.54%Color and Shape:SolidMolecular weight:275.3STS-E412
CAS:STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.Formula:C15H15ClN4O2Purity:99.01%Color and Shape:SolidMolecular weight:318.76PKI-166
CAS:PKI-166: oral EGF-R tyrosine kinase inhibitor (IC50: 0.7 nM), halts growth & spread of many human cancers, including pancreatic.Formula:C20H18N4OPurity:99.2%Color and Shape:SolidMolecular weight:330.38BRD7389
CAS:BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.Formula:C24H18N2O2Purity:99.51%Color and Shape:SolidMolecular weight:366.41Rezivertinib
CAS:Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study central nervous system diseases.Formula:C27H30N6O3Purity:99.26% - 99.98%Color and Shape:SolidMolecular weight:486.57CCT365623 hydrochloride
CAS:CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.Formula:C18H18ClNO4S3Purity:98%Color and Shape:SolidMolecular weight:443.99MS 154
CAS:MS 154 is a potent PROTAC® targeting mutant EGFR in lung cancer, sparing WT-EGFR; effective in mice, with DC50 of 11-25 nM.Formula:C46H54ClFN8O8Color and Shape:SolidMolecular weight:901.42HPK1-IN-2 dihydrochloride
CAS:HPK1-IN-2 dihydrochloride, a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1) with an IC 50 of less than 0.05 µM, demonstrates significant antitumor activity. It additionally exhibits inhibition of Lck kinase activity, with an IC 50 ranging from 0.05 to less than 0.5 µM, and Flt3 kinase activity, with an IC 50 of less than 0.05 µM [1].Formula:C19H22Cl2N6OSColor and Shape:SolidMolecular weight:453.39VEGFR-2-IN-37
CAS:VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.Formula:C18H16N2O2SPurity:98%Color and Shape:SolidMolecular weight:324.4Cremastranone
CAS:Cremastranone: natural homoisoflavanone that hinders human retinal cell proliferation, migration, and tube creation.Formula:C18H18O7Color and Shape:SolidMolecular weight:346.33BMS-599626 Hydrochloride
CAS:BMS-599626 HCl (AC480 HCl) is an oral inhibitor of HER1, HER2, HER4 kinases, potentially blocking tumor growth. IC50: 22/32/190 nM.Formula:C27H28ClFN8O3Purity:99.98%Color and Shape:SolidMolecular weight:567.01FGFR-IN-4
CAS:FGFR-IN-4 is a potent inhibitor of FGFR. FGFR-IN-4 has potential for cancer disease studies.Formula:C24H21N7O2Color and Shape:SolidMolecular weight:439.47BMX-IN-1
CAS:BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosineFormula:C29H24N4O4SPurity:98.38%Color and Shape:SolidMolecular weight:524.59BTK inhibitor 13
CAS:BTK inhibitor 13 (compound 8) is an effective and selective BTK inhibitor(IC50: 1.2 nM).Formula:C29H26FN5O3Purity:98%Color and Shape:SolidMolecular weight:511.55Pivanex
CAS:Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.Formula:C10H18O4Purity:≥98%Color and Shape:SolidMolecular weight:202.25OTS447
CAS:OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .Formula:C27H32ClN3O2Purity:98.78%Color and Shape:SolidMolecular weight:466.02
