EGFR
EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.
Found 572 products of "EGFR"
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Almonertinib
CAS:Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.Formula:C30H35N7O2Purity:99.99%Color and Shape:SolidMolecular weight:525.64Ref: TM-T5462
1mg89.00€5mg197.00€10mg311.00€25mg525.00€50mg757.00€100mg1,035.00€500mg2,110.00€1mL*10mM (DMSO)249.00€G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formula:C22H19F2NO3Purity:97.3%Color and Shape:SolidMolecular weight:383.39Ref: TM-T8742
1mg35.00€5mg71.00€10mg96.00€25mg172.00€50mg248.00€100mg348.00€200mg470.00€1mL*10mM (DMSO)78.00€AG-494
CAS:AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.Formula:C16H12N2O3Purity:98.69%Color and Shape:SolidMolecular weight:280.28Neratinib
CAS:Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formula:C30H29ClN6O3Purity:96.17% - 99.85%Color and Shape:SolidMolecular weight:557.04Osimertinib mesylate
CAS:Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.
Formula:C29H37N7O5SPurity:99.46% - >99.99%Color and Shape:SolidMolecular weight:595.71RG13022
CAS:RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).Formula:C16H14N2O2Purity:98.38%Color and Shape:SolidMolecular weight:266.29RG14620
CAS:RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.Formula:C14H8Cl2N2Purity:99.82% - 99.87%Color and Shape:SolidMolecular weight:275.13Allitinib tosylate
CAS:Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.Formula:C31H26ClFN4O5SPurity:98.46% - 98.68%Color and Shape:SolidMolecular weight:621.08(S)-Sunvozertinib
CAS:(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.Formula:C29H35ClFN7O3Purity:99.64%Color and Shape:SolidMolecular weight:584.08BI-4020
CAS:BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.Formula:C30H38N8O2Purity:97.21% - >99.99%Color and Shape:SolidMolecular weight:542.68Ref: TM-T10534
1mg161.00€5mg376.00€10mg538.00€25mg803.00€50mg1,071.00€100mg1,431.00€200mg1,953.00€1mL*10mM (DMSO)447.00€Avitinib
CAS:Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Formula:C26H26FN7O2Purity:99.81% - >99.99%Color and Shape:SolidMolecular weight:487.53Avitinib maleate
CAS:Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.Formula:C30H30FN7O6Purity:98% - 99.74%Color and Shape:SolidMolecular weight:603.61Alflutinib mesylate
CAS:Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.Formula:C29H35F3N8O5SPurity:97.94% - 99.63%Color and Shape:SolidMolecular weight:664.70(E)-AG 556
CAS:AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.
Formula:C20H20N2O3Purity:99.93%Color and Shape:Light Yellow PowderMolecular weight:336.38NSC 228155
CAS:NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Formula:C11H6N4O4SPurity:99.84%Color and Shape:SolidMolecular weight:290.25Ref: TM-T6908
2mg34.00€5mg48.00€10mg63.00€25mg117.00€50mg178.00€100mg334.00€200mg469.00€1mL*10mM (DMSO)50.00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purity:98.11% - 99.87%Color and Shape:SolidMolecular weight:718.08AZ-5104
CAS:AZ5104 is a potent EGFR inhibitor.Formula:C27H31N7O2Purity:98.40% - 99.59%Color and Shape:Solid PowderMolecular weight:485.58Dacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Formula:C24H25ClFN5O2Purity:99.4% - 99.72%Color and Shape:SolidMolecular weight:469.94Ref: TM-T2483
1mg38.00€2mg49.00€5mg79.00€10mg127.00€25mg173.00€50mg227.00€100mg354.00€200mg444.00€500mg730.00€1mL*10mM (DMSO)79.00€Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFormula:C18H22N2OPurity:98.21% - 99.87%Color and Shape:Yellow SolidMolecular weight:282.38Poziotinib hydrochloride
CAS:Oral poziotinib HCl targets EGFR/HER mutants, inhibiting cancer cell growth.Formula:C23H22Cl3FN4O3Purity:99.69% - 99.81%Color and Shape:SolidMolecular weight:527.8PP 3
CAS:PP 3 is a Negative control for the Src kinase inhibitor PP 2Formula:C11H9N5Purity:98.61%Color and Shape:Whit To Off-White SolidMolecular weight:211.22Osimertinib
CAS:Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.Formula:C28H33N7O2Purity:99.32% - >99.99%Color and Shape:SolidMolecular weight:499.61Ref: TM-T2490
1g138.00€2g197.00€5g329.00€2mg34.00€5mg52.00€10mg55.00€25mg67.00€50mg80.00€100mg94.00€500mg114.00€1mL*10mM (DMSO)52.00€Olmutinib hydrochloride
CAS:Olmutinib is a third-gen EGFR inhibitor for T790M-positive lung cancer, blocking phosphorylation and tumor pathways. Approved in Korea (2016).Formula:C26H28Cl2N6O2SColor and Shape:SolidMolecular weight:559.51Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purity:98.76% - >99.99%Color and Shape:SolidMolecular weight:272.25Ref: TM-T6427
1mg40.00€2mg52.00€5mg84.00€10mg101.00€25mg202.00€50mg326.00€100mg520.00€1mL*10mM (DMSO)82.00€PD158780
CAS:PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.Formula:C14H12BrN5Purity:98.81%Color and Shape:SolidMolecular weight:330.18Ref: TM-T5410
1mg38.00€5mg80.00€10mg113.00€25mg205.00€50mg358.00€100mg523.00€200mg750.00€1mL*10mM (DMSO)93.00€β-Hydroxyisovalerylshikonin
CAS:Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumorFormula:C21H24O7Purity:98.16%Color and Shape:SolidMolecular weight:388.41TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C23H20N6OPurity:99.71%Color and Shape:SolidMolecular weight:396.44Ref: TM-T16996
1mg87.00€2mg124.00€5mg188.00€10mg311.00€25mg628.00€50mg838.00€100mg1,130.00€200mg1,549.00€1mL*10mM (DMSO)215.00€PD153035 hydrochloride
CAS:PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.
Formula:C16H15BrClN3O2Purity:99.39% - ≥95%Color and Shape:SolidMolecular weight:396.67EAI045
CAS:EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Formula:C19H14FN3O3SPurity:98.00% - 99.12%Color and Shape:SolidMolecular weight:383.4AZ7550
CAS:AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Formula:C27H31N7O2Purity:97.07% - 99.75%Color and Shape:SolidMolecular weight:485.58Epidermal Growth Factor
CAS:EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.Formula:C270H401N73O83S7Purity:97.17%Color and Shape:SolidMolecular weight:6222CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Formula:C14H18N2O5Purity:99.68%Color and Shape:White To Off-White SolidMolecular weight:294.3Tyrphostin 23
CAS:Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.Formula:C10H6N2O2Purity:99.7% - 99.86%Color and Shape:Yellow-Tan SolidMolecular weight:186.17EGFR-IN-12
CAS:EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Formula:C21H18F3N5OPurity:98.3% - 99.76%Color and Shape:SolidMolecular weight:413.4Ref: TM-T5168
1mg82.00€5mg159.00€10mg259.00€25mg520.00€50mg740.00€100mg1,008.00€500mg2,015.00€1mL*10mM (DMSO)168.00€Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formula:C22H23ClFN5O3Purity:98.20% - 99.36%Color and Shape:White To Off-White SolidMolecular weight:459.9MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formula:C20H14Cl2FN5O2SPurity:97.6% - >99.99%Color and Shape:SolidMolecular weight:478.33Ref: TM-T4296
1mg60.00€2mg89.00€5mg167.00€10mg260.00€25mg439.00€50mg605.00€100mg802.00€200mg1,099.00€1mL*10mM (DMSO)170.00€AG 555
CAS:AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Formula:C19H18N2O3Purity:98.02% - 99.94%Color and Shape:SolidMolecular weight:322.36WHI-P258
CAS:WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Formula:C16H15N3O2Purity:99.66% - 99.92%Color and Shape:SolidMolecular weight:281.31AG-1478
CAS:AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.
Formula:C16H14ClN3O2Purity:99.03% - 99.71%Color and Shape:SolidMolecular weight:315.75Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purity:97.89% - 98.66%Color and Shape:SolidMolecular weight:491.39EBE-A22
CAS:EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.Formula:C17H16BrN3O2Purity:99.087% - 99.88%Color and Shape:SolidMolecular weight:374.23Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Formula:C24H23ClFN5O2Purity:98.37% - 99.84%Color and Shape:Off-White SolidMolecular weight:467.92WZ-3146
CAS:WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).Formula:C24H25ClN6O2Purity:97.15%Color and Shape:SolidMolecular weight:464.95Ref: TM-T6733
1mg50.00€2mg71.00€5mg92.00€10mg170.00€25mg301.00€50mg484.00€100mg692.00€1mL*10mM (DMSO)101.00€CZC-8004
CAS:CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formula:C17H16FN5Purity:99.29%Color and Shape:SolidMolecular weight:309.34CNX-2006
CAS:CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.Formula:C26H27F4N7O2Purity:98.85% - 99.16%Color and Shape:SolidMolecular weight:545.53Sapitinib
CAS:Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib orFormula:C23H25ClFN5O3Purity:98.89% - 99.83%Color and Shape:SolidMolecular weight:473.93Olmutinib
CAS:Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.Formula:C26H26N6O2SPurity:99.14% - 99.63%Color and Shape:SolidMolecular weight:486.59Ref: TM-T6918
2mg37.00€5mg54.00€10mg84.00€25mg130.00€50mg170.00€100mg268.00€200mg437.00€1mL*10mM (DMSO)56.00€Cyasterone
CAS:Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promisingFormula:C29H44O8Purity:99.32% - 99.70%Color and Shape:SolidMolecular weight:520.65Leptomycin B
CAS:Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.Formula:C33H48O6Purity:97.10% - 99.04%Color and Shape:White Crystalline SolidMolecular weight:540.73Ref: TM-T15735
1mg202.00€2mg341.00€5mg620.00€10mg882.00€25mg1,320.00€50mg1,776.00€100mg2,403.00€1mL*10mM (DMSO)283.00€Genistein
CAS:Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formula:C15H10O5Purity:98.22% - 99.64%Color and Shape:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMolecular weight:270.24
