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EGFR

EGFR

EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.

Found 572 products of "EGFR"

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  • SU5204
    Targetmol
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    SU5204

    CAS:
    SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and
    Formula:C17H15NO2
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:265.31

    Ref: TM-T22431

  • Sulforaphene
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    Sulforaphene

    CAS:
    <p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>
    Formula:C6H9NOS2
    Purity:97.55% - 99.19%
    Color and Shape:Slightly Yellowish Liquid
    Molecular weight:175.27

    Ref: TM-TL0016

  • SYR127063
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    SYR127063

    CAS:
    <p>SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.</p>
    Formula:C23H20ClF3N4O3
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:492.88

    Ref: TM-T34760

  • Tuxobertinib
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    Tuxobertinib

    CAS:
    <p>Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations. BDTX-189 exhibits anticancer activity.</p>
    Formula:C29H29ClN6O4
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:561.03

    Ref: TM-T9072

  • TAS6417
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    TAS6417

    CAS:
    <p>Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>
    Formula:C23H20N6O
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:396.44

    Ref: TM-T16996

  • AG490
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    AG490

    CAS:
    AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.
    Formula:C17H14N2O3
    Purity:98.6% - 99.85%
    Color and Shape:Yellow Solid
    Molecular weight:294.3

    Ref: TM-T2600

  • Epitinib
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    Epitinib

    CAS:
    <p>Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).</p>
    Formula:C24H26N6O2
    Color and Shape:Solid
    Molecular weight:430.5

    Ref: TM-T62397

  • β-Hydroxyisovalerylshikonin
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    β-Hydroxyisovalerylshikonin

    CAS:
    <p>Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor</p>
    Formula:C21H24O7
    Purity:98.16%
    Color and Shape:Solid
    Molecular weight:388.41

    Ref: TM-TN1440

  • Chrysophanol
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    Chrysophanol

    CAS:
    <p>Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.</p>
    Formula:C15H10O4
    Purity:99.44% - 99.91%
    Color and Shape:Physical Description Golden Yellow Plates Or Brown Powder Melting Point 196°C
    Molecular weight:254.24

    Ref: TM-T2995

  • Epidermal Growth Factor
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    Epidermal Growth Factor

    CAS:
    <p>EGF binds EGFR, promotes cell growth &amp; heals diabetic foot ulcers.</p>
    Formula:C270H401N73O83S7
    Purity:97.17%
    Color and Shape:Solid
    Molecular weight:6222

    Ref: TM-T8679

  • Theliatinib tartrate
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    Theliatinib tartrate

    CAS:
    <p>Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), &gt;50x kinase selectivity.</p>
    Formula:C29H32N6O8
    Color and Shape:Solid
    Molecular weight:592.6

    Ref: TM-T72431

  • Mubritinib
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    Mubritinib

    CAS:
    Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
    Formula:C25H23F3N4O2
    Purity:98.61% - 99.85%
    Color and Shape:Solid
    Molecular weight:468.47

    Ref: TM-T6124

  • PD158780
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    PD158780

    CAS:
    <p>PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.</p>
    Formula:C14H12BrN5
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:330.18

    Ref: TM-T5410

  • WS6
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    WS6

    CAS:
    <p>WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.</p>
    Formula:C29H31F3N6O3
    Purity:97.65% - 99.95%
    Color and Shape:Solid
    Molecular weight:568.59

    Ref: TM-T2106

  • PP2
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    PP2

    CAS:
    <p>PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.</p>
    Formula:C15H16ClN5
    Purity:98% - 98.21%
    Color and Shape:White Solid
    Molecular weight:301.77

    Ref: TM-T6266

  • Butein
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    Butein

    CAS:
    Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.
    Formula:C15H12O5
    Purity:98.76% - >99.99%
    Color and Shape:Solid
    Molecular weight:272.25

    Ref: TM-T6427

  • PD153035 hydrochloride
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    PD153035 hydrochloride

    CAS:
    <p>PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.</p>
    Formula:C16H15BrClN3O2
    Purity:99.39% - ≥95%
    Color and Shape:Solid
    Molecular weight:396.67

    Ref: TM-T1761

  • Oritinib mesylate
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    Oritinib mesylate

    CAS:
    <p>Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.</p>
    Formula:C32H41N7O5S
    Color and Shape:Solid
    Molecular weight:635.78

    Ref: TM-T39670

  • RG13022
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    RG13022

    CAS:
    <p>RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).</p>
    Formula:C16H14N2O2
    Purity:98.38%
    Color and Shape:Solid
    Molecular weight:266.29

    Ref: TM-T3545

  • Mutant EGFR inhibitor
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    Mutant EGFR inhibitor

    CAS:
    <p>Selective, potent inhibitor for mutated EGFR: L858R, Exon19 deletion, T790M resistance mutants.</p>
    Formula:C27H30ClN7O2
    Purity:98% - 99.75%
    Color and Shape:Solid
    Molecular weight:520.03

    Ref: TM-T2705