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EGFR

EGFR

EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.

Found 572 products of "EGFR"

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  • Mutant EGFR inhibitor
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    Mutant EGFR inhibitor

    CAS:
    <p>Selective, potent inhibitor for mutated EGFR: L858R, Exon19 deletion, T790M resistance mutants.</p>
    Formula:C27H30ClN7O2
    Purity:98% - 99.75%
    Color and Shape:Solid
    Molecular weight:520.03

    Ref: TM-T2705

  • Almonertinib
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    Almonertinib

    CAS:
    <p>Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.</p>
    Formula:C30H35N7O2
    Purity:99.99%
    Color and Shape:Solid
    Molecular weight:525.64

    Ref: TM-T5462

  • (E)-AG 556
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    (E)-AG 556

    CAS:
    <p>AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.</p>
    Formula:C20H20N2O3
    Purity:99.93%
    Color and Shape:Light Yellow Powder
    Molecular weight:336.38

    Ref: TM-T21853

  • WHI-P258
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    WHI-P258

    CAS:
    <p>WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.</p>
    Formula:C16H15N3O2
    Purity:99.66% - 99.92%
    Color and Shape:Solid
    Molecular weight:281.31

    Ref: TM-T2035

  • WZ4002
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    WZ4002

    CAS:
    <p>WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.</p>
    Formula:C25H27ClN6O3
    Purity:97.51%
    Color and Shape:Solid
    Molecular weight:494.97

    Ref: TM-T6238

  • SU5214
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    SU5214

    CAS:
    <p>SU5214 is a modulator of tyrosine kinase signal transduction.</p>
    Formula:C16H13NO2
    Purity:99.45% - 99.55%
    Color and Shape:Solid
    Molecular weight:251.28

    Ref: TM-T3569

  • AZ7550
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    AZ7550

    CAS:
    <p>AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>
    Formula:C27H31N7O2
    Purity:97.07% - 99.75%
    Color and Shape:Solid
    Molecular weight:485.58

    Ref: TM-T13564

  • Avitinib maleate
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    Avitinib maleate

    CAS:
    Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.
    Formula:C30H30FN7O6
    Purity:98% - 99.74%
    Color and Shape:Solid
    Molecular weight:603.61

    Ref: TM-T3721

  • Tyrphostin A1
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    Tyrphostin A1

    CAS:
    Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .
    Formula:C11H8N2O
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:184.19

    Ref: TM-T7649

  • Epidermal Growth Factor
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    Epidermal Growth Factor

    CAS:
    <p>EGF binds EGFR, promotes cell growth &amp; heals diabetic foot ulcers.</p>
    Formula:C270H401N73O83S7
    Purity:97.17%
    Color and Shape:Solid
    Molecular weight:6222

    Ref: TM-T8679

  • Saracatinib
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    Saracatinib

    CAS:
    <p>Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.</p>
    Formula:C27H32ClN5O5
    Purity:98% - 99.63%
    Color and Shape:Solid
    Molecular weight:542.03

    Ref: TM-T6078

  • PD153035 hydrochloride
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    PD153035 hydrochloride

    CAS:
    <p>PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.</p>
    Formula:C16H15BrClN3O2
    Purity:99.39% - ≥95%
    Color and Shape:Solid
    Molecular weight:396.67

    Ref: TM-T1761

  • EAI045
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    EAI045

    CAS:
    <p>EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.</p>
    Formula:C19H14FN3O3S
    Purity:98.00% - 99.12%
    Color and Shape:Solid
    Molecular weight:383.4

    Ref: TM-T6824

  • MTX-211
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    MTX-211

    CAS:
    <p>MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.</p>
    Formula:C20H14Cl2FN5O2S
    Purity:97.6% - >99.99%
    Color and Shape:Solid
    Molecular weight:478.33

    Ref: TM-T4296

  • NSC 228155
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    NSC 228155

    CAS:
    <p>NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.</p>
    Formula:C11H6N4O4S
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:290.25

    Ref: TM-T6908

  • PD168393
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    PD168393

    CAS:
    <p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>
    Formula:C17H13BrN4O
    Purity:99.13% - 99.83%
    Color and Shape:Solid
    Molecular weight:369.22

    Ref: TM-T6932

  • Tyrphostin AG30
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    Tyrphostin AG30

    CAS:
    <p>Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.</p>
    Formula:C10H7NO4
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:205.17

    Ref: TM-T7101

  • EGFR/ErbB-2/ErbB-4 inhibitor-2
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    EGFR/ErbB-2/ErbB-4 inhibitor-2

    CAS:
    <p>EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)</p>
    Formula:C23H21N3O3
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:387.43

    Ref: TM-T21954

  • Endoxifen (Z-isomer)
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    Endoxifen (Z-isomer)

    CAS:
    Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.
    Formula:C25H27NO2
    Purity:99.19% - 99.81%
    Color and Shape:Solid
    Molecular weight:373.49

    Ref: TM-T2280

  • PD-161570
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    PD-161570

    CAS:
    PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.
    Formula:C26H35Cl2N7O
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:532.51

    Ref: TM-T23127