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EGFR

EGFR

EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.

Found 572 products of "EGFR"

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  • PP2

    CAS:
    <p>PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.</p>
    Formula:C15H16ClN5
    Purity:98% - 98.21%
    Color and Shape:White Solid
    Molecular weight:301.77
  • Tyrphostin AG30

    CAS:
    <p>Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.</p>
    Formula:C10H7NO4
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:205.17
  • PD-161570

    CAS:
    <p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>
    Formula:C26H35Cl2N7O
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:532.51
  • Lazertinib

    CAS:
    <p>Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.</p>
    Formula:C30H34N8O3
    Purity:98.7% - 99.90%
    Color and Shape:Solid
    Molecular weight:554.64
  • Tyrphostin A1

    CAS:
    <p>Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .</p>
    Formula:C11H8N2O
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:184.19
  • WZ4002

    CAS:
    <p>WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.</p>
    Formula:C25H27ClN6O3
    Purity:97.51%
    Color and Shape:Solid
    Molecular weight:494.97
  • MAZ51

    CAS:
    <p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>
    Formula:C21H18N2O
    Purity:98.53%
    Color and Shape:Solid
    Molecular weight:314.38
  • Gefitinib-based PROTAC 3

    CAS:
    <p>Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).</p>
    Formula:C47H57ClFN7O8S
    Purity:97.29% - 98.25%
    Color and Shape:Solid
    Molecular weight:934.51
  • Dacomitinib hydrate

    CAS:
    <p>Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of</p>
    Formula:C24H27ClFN5O3
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:487.96
  • Almonertinib

    CAS:
    <p>Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.</p>
    Formula:C30H35N7O2
    Purity:99.99%
    Color and Shape:Solid
    Molecular weight:525.64
  • G5-7

    CAS:
    <p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>
    Formula:C22H19F2NO3
    Purity:97.3%
    Color and Shape:Solid
    Molecular weight:383.39
  • AG-494

    CAS:
    <p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>
    Formula:C16H12N2O3
    Purity:98.69%
    Color and Shape:Solid
    Molecular weight:280.28
  • Neratinib

    CAS:
    <p>Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.</p>
    Formula:C30H29ClN6O3
    Purity:96.17% - 99.85%
    Color and Shape:Solid
    Molecular weight:557.04
  • Osimertinib mesylate

    CAS:
    <p>Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C29H37N7O5S
    Purity:99.46% - >99.99%
    Color and Shape:Solid
    Molecular weight:595.71
  • RG13022

    CAS:
    <p>RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).</p>
    Formula:C16H14N2O2
    Purity:98.38%
    Color and Shape:Solid
    Molecular weight:266.29
  • RG14620

    CAS:
    <p>RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.</p>
    Formula:C14H8Cl2N2
    Purity:99.82% - 99.87%
    Color and Shape:Solid
    Molecular weight:275.13
  • Allitinib tosylate

    CAS:
    <p>Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.</p>
    Formula:C31H26ClFN4O5S
    Purity:98.46% - 98.68%
    Color and Shape:Solid
    Molecular weight:621.08
  • (S)-Sunvozertinib

    CAS:
    <p>(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.</p>
    Formula:C29H35ClFN7O3
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:584.08
  • BI-4020

    CAS:
    <p>BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.</p>
    Formula:C30H38N8O2
    Purity:97.21% - >99.99%
    Color and Shape:Solid
    Molecular weight:542.68
  • Avitinib

    CAS:
    <p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>
    Formula:C26H26FN7O2
    Purity:99.81% - >99.99%
    Color and Shape:Solid
    Molecular weight:487.53