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EGFR

EGFR

EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.

Found 572 products of "EGFR"

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  • Derazantinib dihydrochloride
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    Derazantinib dihydrochloride

    CAS:
    <p>Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.</p>
    Formula:C29H31Cl2FN4O
    Color and Shape:Solid
    Molecular weight:541.49

    Ref: TM-T70143

  • Tyrphostin AG 528
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    Tyrphostin AG 528

    CAS:
    <p>Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).</p>
    Formula:C18H14N2O3
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:306.32

    Ref: TM-T4528

  • AG 1406
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    AG 1406

    CAS:
    <p>AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.</p>
    Formula:C16H18N2O
    Purity:98.12%
    Color and Shape:Solid
    Molecular weight:254.33

    Ref: TM-T4554

  • TAS0728
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    TAS0728

    CAS:
    <p>TAS0728 is a HER2 inhibitor, with antitumor activity</p>
    Formula:C26H32N8O3
    Purity:97.78%
    Color and Shape:Solid
    Molecular weight:504.58

    Ref: TM-T7819

  • NRC-2694
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    NRC-2694

    CAS:
    <p>NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.</p>
    Formula:C24H26N4O3
    Purity:99.90%
    Color and Shape:Solid
    Molecular weight:418.49

    Ref: TM-T16343

  • Theliatinib
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    Theliatinib

    CAS:
    <p>Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).</p>
    Formula:C25H26N6O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:442.51

    Ref: TM-T7322

  • (E)-AG 99
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    (E)-AG 99

    CAS:
    (E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).
    Formula:C10H8N2O3
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:204.18

    Ref: TM-T5155

  • JCN037
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    JCN037

    CAS:
    <p>JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).</p>
    Formula:C16H11BrFN3O2
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:376.18

    Ref: TM-T8431

  • PKI-166 hydrochloride
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    PKI-166 hydrochloride

    CAS:
    <p>EGFR-kinase inhibitor, IC50 0.7 nM, &gt;3000x selective, cuts metastasis and angiogenesis in mice, antihypertensive, oral use.</p>
    Formula:C20H19ClN4O
    Color and Shape:Solid
    Molecular weight:366.85

    Ref: TM-T36643

  • SU 4313
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    SU 4313

    CAS:
    SU 4313 is a bioactive chemical.
    Formula:C18H17NO
    Purity:99.51% - 99.89%
    Color and Shape:Solid
    Molecular weight:263.33

    Ref: TM-T3568

  • EGFR/ErbB-2/ErbB-4 inhibitor-2
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    EGFR/ErbB-2/ErbB-4 inhibitor-2

    CAS:
    <p>EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)</p>
    Formula:C23H21N3O3
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:387.43

    Ref: TM-T21954

  • Oritinib mesylate
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    Oritinib mesylate

    CAS:
    <p>Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.</p>
    Formula:C32H41N7O5S
    Color and Shape:Solid
    Molecular weight:635.78

    Ref: TM-T39670

  • Theliatinib tartrate
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    Theliatinib tartrate

    CAS:
    <p>Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), &gt;50x kinase selectivity.</p>
    Formula:C29H32N6O8
    Color and Shape:Solid
    Molecular weight:592.6

    Ref: TM-T72431

  • Olmutinib
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    Olmutinib

    CAS:
    Olmutinib (BI1482694) is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
    Formula:C26H26N6O2S
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:486.59

    Ref: TM-T8460

  • AEE788
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    AEE788

    CAS:
    <p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>
    Formula:C27H32N6
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:440.58

    Ref: TM-T2116

  • WHI-P180
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    WHI-P180

    CAS:
    WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.
    Formula:C16H15N3O3
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:297.31

    Ref: TM-T2032

  • NRC-2694 hydrochloride
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    NRC-2694 hydrochloride

    CAS:
    <p>NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.</p>
    Formula:C24H27ClN4O3
    Color and Shape:Solid
    Molecular weight:454.95

    Ref: TM-T71332

  • Trastuzumab
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    Trastuzumab

    CAS:
    Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.
    Purity:97.1% (SDS-PAGE); 99.2% (SEC-HPLC) - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%
    Color and Shape:Liquid
    Molecular weight:Approximately 145.53 kDa

    Ref: TM-T9912

  • Sulforaphene
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    Sulforaphene

    CAS:
    <p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>
    Formula:C6H9NOS2
    Purity:97.55% - 99.19%
    Color and Shape:Slightly Yellowish Liquid
    Molecular weight:175.27

    Ref: TM-TL0016

  • SU5204
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    SU5204

    CAS:
    SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and
    Formula:C17H15NO2
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:265.31

    Ref: TM-T22431