EGFR
EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.
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Nazartinib
CAS:1508250-71-2
Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory …
Formula:
C26H31ClN6O2
Purity:
98% - ≥95%
Color and Shape:
Solid Powder
Molecular weight:
495.02
Ref: TM-T3506
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 522.00 € | ||
| 500mg | 1,133.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
PD-089828
CAS:179343-17-0
PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).
Formula:
C18H18Cl2N6O
Purity:
96.78%
Color and Shape:
Solid
Molecular weight:
405.28
Ref: TM-T8976
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 365.00 € | ||
| 100mg | 537.00 € | ||
| 500mg | 1,137.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Almonertinib hydrochloride
CAS:2134096-03-8
Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation.
Formula:
C30H36ClN7O2
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
562.1
Ref: TM-T5675
| 1mg | 90.00 € | ||
| 5mg | 182.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 525.00 € | ||
| 50mg | 740.00 € | ||
| 100mg | 981.00 € | ||
| 500mg | 1,989.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Naquotinib mesylate
CAS:1448237-05-5
Naquotinib mesylate (ASP8273 (mesylate)) is an orally available, mutant-selective and irreversible inhibitor of EGFR(iC50s of …
Formula:
C31H46N8O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
658.81
Ref: TM-T12175
| 2mg | 63.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
BMS-690514
CAS:859853-30-8
BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s …
Formula:
C19H24N6O2
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
368.43
Ref: TM-T14677
| 2mg | 136.00 € | ||
| 5mg | 222.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
ZM323881 hydrochloride
CAS:193000-39-4
ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.
Formula:
C22H19ClFN3O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
411.86
Ref: TM-T1991
| 5mg | 71.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 233.00 € | ||
| 50mg | 396.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Thursday 9 Jan 2025
Icotinib
CAS:610798-31-7
Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with …
Formula:
C22H21N3O4
Purity:
100%
Color and Shape:
Solid
Molecular weight:
391.42
Ref: TM-T6153
| 1mg | 48.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 518.00 € | ||
| 100mg | 700.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Thursday 9 Jan 2025
Icotinib Hydrochloride
CAS:1204313-51-8
Icotinib Hydrochloride, an oral EGFR inhibitor (BPI-2009H), may halt cancer growth by blocking EGFR signaling.
Formula:
C22H22ClN3O4
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
427.88
Ref: TM-T2307
| 5mg | 60.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 139.00 € | ||
| 50mg | 225.00 € | ||
| 100mg | 333.00 € | ||
| 200mg | 495.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Thursday 9 Jan 2025
lavendustin A
CAS:125697-92-9
lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine …
Formula:
C21H19NO6
Purity:
98%
Color and Shape:
Off-White Solid
Molecular weight:
381.38
Ref: TM-T4183
| 1mg | 74.00 € | ||
| 5mg | 142.00 € |
Estimated delivery in United States, on Thursday 9 Jan 2025
TAK-285
CAS:871026-44-7
TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, …
Formula:
C26H25ClF3N5O3
Purity:
99.17%
Color and Shape:
Solid
Molecular weight:
547.96
Ref: TM-T6039
| 1mg | 40.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 227.00 € | ||
| 50mg | 371.00 € | ||
| 100mg | 551.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Thursday 9 Jan 2025
MAPK-IN-2
MAPK-IN-2 (compound 3h) is an efficacious MAPK inhibitor with antineoplastic properties that significantly hinders proliferation …
Formula:
C20H11Cl2N3O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
380.23
Ref: TM-T79572
| 5mg | 897.00 € | ||
| 25mg | 1,498.00 € | ||
| 50mg | 2,242.00 € |
Estimated delivery in United States, on Thursday 9 Jan 2025
DBPR112
CAS:1226549-49-0
DBPR112: oral furanopyrimidine EGFR inhibitor; IC50: 15 nM (EGFRWT), 48 nM (L858R/T790M); blocks ATP site, …
Formula:
C32H31N5O3
Purity:
98.29%
Color and Shape:
Solid
Molecular weight:
533.62
Ref: TM-T10965
| 1mg | 75.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 300.00 € | ||
| 25mg | 484.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 888.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
BKI-1369
CAS:1951431-22-3
BKI-1369 is a bumped kinase inhibitor. BKI-1369 increases hERG-inhibitory activity (IC50:1.52 μM).
Formula:
C23H27N7O
Color and Shape:
Solid
Molecular weight:
417.51
Ref: TM-T10556
| 5mg | 444.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,854.00 € | ||
| 100mg | 2,340.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
Epitinib succinate
CAS:2252334-12-4
Epitinib succinate (HMPL-813 succinate) is an orally active and brain penetration EGFR tyrosine kinase inhibitor …
Formula:
C28H32N6O6
Purity:
97.43% - 99.47%
Color and Shape:
Solid
Molecular weight:
548.59
Ref: TM-T35914
| 1mg | 74.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 266.00 € | ||
| 25mg | 440.00 € | ||
| 50mg | 602.00 € | ||
| 100mg | 825.00 € | ||
| 500mg | 1,653.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
EGFR-IN-2
CAS:1643497-70-4
EGFR-IN-2 is a non-covalent, mutation-selective and irreversible second-generation EGFR inhibitor.
Formula:
C26H33N9O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
551.66
Ref: TM-T11159
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
Nuvenzepine
CAS:96487-37-5
Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.
Formula:
C19H20N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
336.39
Ref: TM-T16362
| 25mg | 1,410.00 € | ||
| 50mg | 1,875.00 € | ||
| 100mg | 2,317.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
Rezivertinib
CAS:1835667-12-3
Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study …
Formula:
C27H30N6O3
Purity:
99.43% - 99.43%
Color and Shape:
Liquid
Molecular weight:
486.57
Ref: TM-T36644
| 1mg | 169.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
CHMFL-EGFR-202
CAS:2089381-40-6
CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase (IC50s: 5.3 nM and 8.3 …
Formula:
C25H24ClN7O2
Purity:
99.19%
Color and Shape:
Solid
Molecular weight:
489.96
Ref: TM-T10802
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 552.00 € | ||
| 50mg | 772.00 € | ||
| 100mg | 1,053.00 € | ||
| 1mL*10mM (DMSO) | 304.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
CGP77675
CAS:234772-64-6
CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of …
Formula:
C26H29N5O2
Purity:
98.23%
Color and Shape:
Solid
Molecular weight:
443.54
Ref: TM-T30855
| 1mg | 51.00 € | ||
| 2mg | 69.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 347.00 € | ||
| 50mg | 555.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
SKLB 1028
CAS:1350544-93-2
SKLB 1028, an oral EGFR/FLT3/Abl inhibitor, excels in AML and CML with Abl mutations.
Formula:
C24H29N9
Purity:
99.71% - 99.85%
Color and Shape:
Solid
Molecular weight:
443.55
Ref: TM-T34656
| 1mg | 56.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 378.00 € | ||
| 50mg | 560.00 € | ||
| 100mg | 802.00 € | ||
| 500mg | 1,616.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
