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EGFR

EGFR

EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.

Found 572 products of "EGFR"

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  • Avitinib maleate
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    Avitinib maleate

    CAS:
    Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.
    Formula:C30H30FN7O6
    Purity:98% - 99.74%
    Color and Shape:Solid
    Molecular weight:603.61

    Ref: TM-T3721

  • Alflutinib mesylate
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    Alflutinib mesylate

    CAS:
    <p>Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.</p>
    Formula:C29H35F3N8O5S
    Purity:97.94% - 99.63%
    Color and Shape:Solid
    Molecular weight:664.7

    Ref: TM-T7175

  • (E)-AG 556
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    (E)-AG 556

    CAS:
    <p>AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.</p>
    Formula:C20H20N2O3
    Purity:99.93%
    Color and Shape:Light Yellow Powder
    Molecular weight:336.38

    Ref: TM-T21853

  • NSC 228155
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    NSC 228155

    CAS:
    <p>NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.</p>
    Formula:C11H6N4O4S
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:290.25

    Ref: TM-T6908

  • Afatinib Dimaleate
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    Afatinib Dimaleate

    CAS:
    <p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>
    Formula:C32H33ClFN5O11
    Purity:98.11% - 99.87%
    Color and Shape:Solid
    Molecular weight:718.08

    Ref: TM-T1773

  • AZ-5104
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    AZ-5104

    CAS:
    AZ5104 is a potent EGFR inhibitor.
    Formula:C27H31N7O2
    Purity:98.40% - 99.59%
    Color and Shape:Solid Powder
    Molecular weight:485.58

    Ref: TM-T2491

  • Dacomitinib
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    Dacomitinib

    CAS:
    <p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>
    Formula:C24H25ClFN5O2
    Purity:99.4% - 99.72%
    Color and Shape:Solid
    Molecular weight:469.94

    Ref: TM-T2483

  • Tyrphostin A9
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    Tyrphostin A9

    CAS:
    <p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>
    Formula:C18H22N2O
    Purity:98.21% - 99.87%
    Color and Shape:Yellow Solid
    Molecular weight:282.38

    Ref: TM-T2479

  • Poziotinib hydrochloride
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    Poziotinib hydrochloride

    CAS:
    <p>Oral poziotinib HCl targets EGFR/HER mutants, inhibiting cancer cell growth.</p>
    Formula:C23H22Cl3FN4O3
    Purity:99.69% - 99.81%
    Color and Shape:Solid
    Molecular weight:527.8

    Ref: TM-T8758

  • PP 3
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    PP 3

    CAS:
    <p>PP 3 is a Negative control for the Src kinase inhibitor PP 2</p>
    Formula:C11H9N5
    Purity:98.61%
    Color and Shape:Whit To Off-White Solid
    Molecular weight:211.22

    Ref: TM-T23176

  • Osimertinib
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    Osimertinib

    CAS:
    <p>Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.</p>
    Formula:C28H33N7O2
    Purity:99.32% - >99.99%
    Color and Shape:Solid
    Molecular weight:499.61

    Ref: TM-T2490

  • Butein
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    Butein

    CAS:
    Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.
    Formula:C15H12O5
    Purity:98.76% - >99.99%
    Color and Shape:Solid
    Molecular weight:272.25

    Ref: TM-T6427

  • PD158780
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    PD158780

    CAS:
    <p>PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.</p>
    Formula:C14H12BrN5
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:330.18

    Ref: TM-T5410

  • β-Hydroxyisovalerylshikonin
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    β-Hydroxyisovalerylshikonin

    CAS:
    <p>Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor</p>
    Formula:C21H24O7
    Purity:98.16%
    Color and Shape:Solid
    Molecular weight:388.41

    Ref: TM-TN1440

  • TAS6417
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    TAS6417

    CAS:
    <p>Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>
    Formula:C23H20N6O
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:396.44

    Ref: TM-T16996

  • PD153035 hydrochloride
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    PD153035 hydrochloride

    CAS:
    <p>PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.</p>
    Formula:C16H15BrClN3O2
    Purity:99.39% - ≥95%
    Color and Shape:Solid
    Molecular weight:396.67

    Ref: TM-T1761

  • EAI045
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    EAI045

    CAS:
    <p>EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.</p>
    Formula:C19H14FN3O3S
    Purity:98.00% - 99.12%
    Color and Shape:Solid
    Molecular weight:383.4

    Ref: TM-T6824

  • AZ7550
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    AZ7550

    CAS:
    <p>AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>
    Formula:C27H31N7O2
    Purity:97.07% - 99.75%
    Color and Shape:Solid
    Molecular weight:485.58

    Ref: TM-T13564

  • Epidermal Growth Factor
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    Epidermal Growth Factor

    CAS:
    <p>EGF binds EGFR, promotes cell growth &amp; heals diabetic foot ulcers.</p>
    Formula:C270H401N73O83S7
    Purity:97.17%
    Color and Shape:Solid
    Molecular weight:6222

    Ref: TM-T8679

  • CP-380736
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    CP-380736

    CAS:
    CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.
    Formula:C14H18N2O5
    Purity:99.68%
    Color and Shape:White To Off-White Solid
    Molecular weight:294.3

    Ref: TM-T19814