FAK
FAK (focal adhesion kinase) inhibitors target FAK, a kinase involved in cell adhesion, migration, and angiogenesis. FAK is frequently overexpressed in tumors and contributes to the formation of new blood vessels that supply nutrients to the tumor. Inhibiting FAK can disrupt these processes, making FAK inhibitors valuable tools in cancer therapy and angiogenesis research. At CymitQuimica, we provide a comprehensive range of high-quality FAK inhibitors to support your research in cell biology, cancer, and angiogenesis.
Found 72 products of "FAK"
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Chloropyramine hydrochloride
CAS:<p>Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.</p>Formula:C16H20ClN3·HClPurity:99.45% - 99.8%Color and Shape:SolidMolecular weight:326.26ALK inhibitor 1
CAS:<p>ALK inhibitor 1 is a selective ALK kinase inhibitor.</p>Formula:C23H28BrN7O3SPurity:98.27%Color and Shape:SolidMolecular weight:562.48ALK inhibitor 2
CAS:<p>ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.</p>Formula:C23H28ClN7O3SPurity:99.77% - >99.99%Color and Shape:SolidMolecular weight:518.03Ifebemtinib FA
<p>BI-853520 FA (Ifebemtinib FA) is an orally active inhibitor of adhesion patch kinase with anticancer and antiproliferative activity for ovarian and lung cancer.</p>Formula:C29H30F4N6O6Purity:98.05% - 99.73%Color and Shape:SolidMolecular weight:634.58Lewis y tetrasaccharide
CAS:<p>Lewis Y tetrasaccharide, a derivative of Lewis X, is an antigen linked to ovarian cancer metastasis and bad prognosis.</p>Formula:C26H45NO19Color and Shape:SolidMolecular weight:675.63GSK215
CAS:<p>GSK215: potent, selective PROTAC degrader of FAK (pDC50=8.4), combines FAK inhibitor VS-4718 and VHL E3 ligase binder, causes fast, lasting FAK degradation.</p>Formula:C50H59F3N10O6SPurity:99.3%Color and Shape:SoildMolecular weight:985.13Defactinib analogue-1
CAS:<p>Defactinib analogue-1 (Compound 7) serves as a ligand for the target protein FAK, and is utilized in the synthesis of PROTAC FAK degrader 1.</p>Formula:C20H20F3N5O3SColor and Shape:SolidMolecular weight:467.47FAK PROTAC B5
CAS:<p>FAK PROTAC B5: a degrader with 14.9 nM IC50, strong degradation, anti-growth, good plasma stability, and fair permeability.</p>Formula:C41H43ClN10O7Color and Shape:SolidMolecular weight:823.32119738-71-3
CAS:<p>Compound 2119738-71-3 interacts with the FAK receptor.</p>Formula:C25H29ClFN7O2Purity:98%Color and Shape:SolidMolecular weight:513.99FAK-IN-9
CAS:<p>FAK-IN-9 (8f) is a potent oral FAK inhibitor, IC50 of 27.44 nM; induces TNBC cell apoptosis.</p>Formula:C36H38ClN7O8SColor and Shape:SolidMolecular weight:764.25FAK-IN-7
CAS:<p>FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.</p>Formula:C16H13N3OSPurity:98.18%Color and Shape:SolidMolecular weight:295.36Tyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Color and Shape:Odour SolidAdhesamine diTFA
CAS:<p>Adhesamine diTFA, a dumbbell-shaped molecule, activates the MAPK/FAK pathway. It promotes adhesion and growth in mammalian cells and accelerates differentiation and enhances the survival rate of primary cultured mouse hippocampal neurons.</p>Formula:C28H32Cl2F6N8O6S2Color and Shape:SolidMolecular weight:825.63VnP-16
<p>VnP-16 enhances bone formation by stimulating the differentiation and activity of osteoblasts via direct β1 integrin engagement, which subsequently activates</p>Formula:C82H112N20O17Purity:98%Color and Shape:SolidMolecular weight:1649.89FAK-IN-1
CAS:<p>FAK-IN-1 is a FAK inhibitor with anticancer activities (WO2020231726 (Example 27)).</p>Formula:C24H26F3N7O4SColor and Shape:SolidMolecular weight:565.57FAK-IN-10
CAS:<p>FAK-IN-10 is an inhibitor of FAK (IC50:76.3 μM).FAK-IN-10 z MCF-7 and A431 cell lines showed antitumor activity with IC50 of 4.23 and 0.78 μM, respectively.</p>Formula:C15H10BrN3O2SPurity:99.78%Color and Shape:SoildMolecular weight:376.23MLK3-IN-1
<p>MLK3-IN-1 (Compound 37) is a selective inhibitor of mixed-lineage kinase 3 (MLK3) with an IC50 of less than 1 nM. It also inhibits FAK with an IC50 of 15.5 μM. In both murine and human liver microsomes, MLK3-IN-1 demonstrates excellent metabolic stability.</p>Formula:C20H16F6N4O2SColor and Shape:SolidMolecular weight:490.422MY-1576
<p>MY-1576 is a FAK inhibitor with an IC50 of 8 nM. It activates the Hippo pathway, thereby inhibiting YAP/TAZ regulation. Additionally, MY-1576 effectively suppresses tumor growth in the KYSE30 xenograft mouse model, demonstrates good safety, and efficiently downregulates FAK autophosphorylation and YAP/TAZ levels in vivo.</p>Formula:C25H29ClN8O2Color and Shape:SolidMolecular weight:509FAK-IN-27
<p>FAK-IN-27 (compound 8A) is a potent and selective inhibitor of FAK, with an IC50 of 4.968 nM. It effectively inhibits the proliferation of H1299 cells, with an IC50 of 0.28 μM, and is applicable for research in non-small cell lung cancer (NSCLC).</p>Formula:C32H28ClN5O6Color and Shape:SolidMolecular weight:613.17281FAK-IN-14
CAS:<p>FAK-IN-14 is a FAK inhibitor that induces apoptosis and cell cycle arrest. FAK-IN-14 has a more significant inhibitory effect on FAK, FGFR1 and Pyk2.</p>Formula:C21H24BrN7OSPurity:99.7%Color and Shape:SoildMolecular weight:502.43
