FAK
FAK (focal adhesion kinase) inhibitors target FAK, a kinase involved in cell adhesion, migration, and angiogenesis. FAK is frequently overexpressed in tumors and contributes to the formation of new blood vessels that supply nutrients to the tumor. Inhibiting FAK can disrupt these processes, making FAK inhibitors valuable tools in cancer therapy and angiogenesis research. At CymitQuimica, we provide a comprehensive range of high-quality FAK inhibitors to support your research in cell biology, cancer, and angiogenesis.
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Y15
CAS:4506-66-5
Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation …
Formula:
C6H14Cl4N4
Purity:
98% - 98%
Color and Shape:
Dark Brown Crystals
Molecular weight:
284.01
Ref: TM-T7119
| 10mg | 50.00 € | ||
| 25mg | 68.00 € | ||
| 50mg | 81.00 € | ||
| 100mg | 134.00 € | ||
| 200mg | 184.00 € | ||
| 500mg | 324.00 € | ||
| 1mL*10mM (DMSO) | 48.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
PF-431396
CAS:717906-29-1
PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
Formula:
C22H21F3N6O3S
Purity:
98.48% - 99.82%
Color and Shape:
Solid
Molecular weight:
506.5
Ref: TM-T2314
| 5mg | 59.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 148.00 € | ||
| 50mg | 249.00 € | ||
| 100mg | 420.00 € | ||
| 200mg | 617.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Fangchinoline
CAS:436-77-1
Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.
Formula:
C37H40N2O6
Purity:
98.81% - 99.98%
Color and Shape:
Solid
Molecular weight:
608.72
Ref: TM-T3122
| 5mg | 50.00 € | ||
| 10mg | 67.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 143.00 € | ||
| 100mg | 206.00 € | ||
| 500mg | 514.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
AMP-945
CAS:1393653-34-3
AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.
Formula:
C28H32F3N5O2
Purity:
99.60%
Color and Shape:
Solid
Molecular weight:
527.58
Ref: TM-T9576
| 1mg | 95.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 522.00 € | ||
| 50mg | 738.00 € | ||
| 100mg | 1,012.00 € | ||
| 1mL*10mM (DMSO) | 248.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
PF-562271 hydrochloride
CAS:939791-41-0
PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of …
Formula:
C21H20F3N7O3SHCl
Purity:
98.52%
Color and Shape:
Solid
Molecular weight:
543.95
Ref: TM-T21768
| 5mg | 77.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 209.00 € | ||
| 100mg | 309.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
PF-573228
CAS:869288-64-2
PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is …
Formula:
C22H20F3N5O3S
Purity:
96.58% - 98.86%
Color and Shape:
Solid
Molecular weight:
491.49
Ref: TM-T2001
| 5mg | 54.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 218.00 € | ||
| 100mg | 346.00 € | ||
| 500mg | 674.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Nitidine chloride
CAS:13063-04-2
1.
Formula:
C21H18ClNO4
Purity:
96.59% - 98.91%
Color and Shape:
Solid
Molecular weight:
383.82
Ref: TM-T5S0761
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 441.00 € | ||
| 500mg | 916.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
BI-4464
CAS:1227948-02-8
BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 …
Formula:
C28H28F3N5O4
Purity:
97.43%
Color and Shape:
Solid
Molecular weight:
555.55
Ref: TM-T5480
| 1mg | 57.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 335.00 € | ||
| 50mg | 503.00 € | ||
| 100mg | 703.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Batatasin III
CAS:56684-87-8
Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT …
Formula:
C15H16O3
Purity:
99.16%
Color and Shape:
Solid
Molecular weight:
244.29
Ref: TM-TN1433
| 1mg | 103.00 € | ||
| 2mg | 155.00 € | ||
| 5mg | 254.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 592.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 23 Dec 2024
Defactinib
CAS:1073154-85-4
Defactinib (VS-6063) is a second-generation inhibitor of FAK. Defactinib has potential antitumor activity. Cost-effective and …
Formula:
C20H21F3N8O3S
Purity:
98% - 99.8%
Color and Shape:
Solid
Molecular weight:
510.49
Ref: TM-T1996
| 1mg | 37.00 € | ||
| 2mg | 48.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 139.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
NVP-TAE 226
CAS:761437-28-9
NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, …
Formula:
C23H25ClN6O3
Purity:
98.07% - 99.17%
Color and Shape:
Solid
Molecular weight:
468.94
Ref: TM-T1918
| 1mg | 48.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 99.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 555.00 € | ||
| 1mL*10mM (DMSO) | 101.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
PND-1186
CAS:1061353-68-1
PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).
Formula:
C25H26F3N5O3
Purity:
99.14% - ≥98%
Color and Shape:
Solid
Molecular weight:
501.5
Ref: TM-T1950
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 199.00 € | ||
| 100mg | 289.00 € | ||
| 500mg | 696.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
CEP-37440
CAS:1391712-60-9
CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular …
Formula:
C30H38ClN7O3
Purity:
99.01% - 99.98%
Color and Shape:
Solid
Molecular weight:
580.12
Ref: TM-T2655
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 251.00 € | ||
| 50mg | 477.00 € | ||
| 100mg | 693.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
PF-562271
CAS:717907-75-0
PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
Formula:
C21H20F3N7O3S
Purity:
100% - 97.65%
Color and Shape:
Solid
Molecular weight:
507.49
Ref: TM-T2465
| 1mg | 58.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 156.00 € | ||
| 25mg | 255.00 € | ||
| 50mg | 370.00 € | ||
| 100mg | 555.00 € | ||
| 500mg | 1,163.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
PF-03814735
CAS:942487-16-3
PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 …
Formula:
C23H25F3N6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
474.48
Ref: TM-T6936
| 1mg | 44.00 € |
Estimated delivery in United States, on Monday 30 Dec 2024
Defactinib hydrochloride
CAS:1073160-26-5
Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.
Formula:
C20H22ClF3N8O3S
Purity:
98.06%
Color and Shape:
Solid
Molecular weight:
546.95
Ref: TM-T15092
| 2mg | 50.00 € | ||
| 5mg | 72.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
FAK inhibitor 2
CAS:2354405-14-2
FAK inhibitor 2, antitumor and anti-angiogenesis activitiesis ,is a potent focal adhesion kinase (FAK) inhibitor …
Formula:
C29H33F3N8O2S2
Color and Shape:
Solid
Molecular weight:
646.75
Ref: TM-T11260
| 25mg | 1,141.00 € | ||
| 50mg | 1,507.00 € | ||
| 100mg | 2,340.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
Conteltinib
CAS:1384860-29-0
Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It …
Formula:
C32H45N9O3S
Purity:
98.12% - 99.54%
Color and Shape:
Solid
Molecular weight:
635.82
Ref: TM-T14997
| 1mg | 96.00 € | ||
| 5mg | 229.00 € | ||
| 10mg | 383.00 € | ||
| 25mg | 666.00 € | ||
| 50mg | 915.00 € | ||
| 100mg | 1,289.00 € | ||
| 1mL*10mM (DMSO) | 328.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
NAMI-A
CAS:201653-76-1
NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion …
Formula:
C8H15Cl4N4ORuS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
458.18
Ref: TM-T16266
| 1mg | 51.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 347.00 € | ||
| 50mg | 637.00 € | ||
| 100mg | 922.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
Compound 1T-0219 (SC)
CAS:383147-92-0
Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation …
Formula:
C20H19N3O7
Purity:
90%
Color and Shape:
Solid
Molecular weight:
413.38
Ref: TM-T9545
| 1mg | 143.00 € | ||
| 5mg | 312.00 € | ||
| 10mg | 465.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,049.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
