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Thrombin

Thrombin

Thrombin inhibitors are compounds that block thrombin, an enzyme involved in the blood coagulation process that also has a role in promoting angiogenesis. Thrombin can stimulate the formation of new blood vessels in tumors, aiding in their growth and metastasis. By inhibiting thrombin, these compounds can reduce angiogenesis and tumor progression. Thrombin inhibitors are important in both cancer research and the study of vascular diseases. At CymitQuimica, we provide a selection of high-quality thrombin inhibitors to support your research in hemostasis, oncology, and angiogenesis.

Found 47 products of "Thrombin"

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  • NP-313

    CAS:
    <p>NP-313 (NSC-4264) is a potent antithrombotic that blocks platelet aggregation via thromboxane A2 synthesis inhibition and targets SOCC-mediated Ca2+ efflux.</p>
    Formula:C12H8ClNO3
    Purity:98.97%
    Color and Shape:Solid
    Molecular weight:249.65
  • SCH79797 dihydrochloride

    CAS:
    <p>SCH79797 dihydrochloride is a PAR1 antagonist with IC50 70 nM, Ki 35 nM, antiproliferative, and pro-apoptotic properties.</p>
    Formula:C23H27Cl2N5
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:444.4
  • Thrombin inhibitor 1

    CAS:
    <p>Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).</p>
    Formula:C22H20Cl2F2N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:497.32
  • Odiparcil

    CAS:
    <p>Odiparcil is an orally active beta-d-thioxyloside analog.</p>
    Formula:C15H16O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.35
  • LK-732

    CAS:
    <p>LK-732 is a thrombin inhibitor with antithrombotic activity. It exhibits dose-dependent inhibition in models of hypercoagulability, with an IC50 value of 1.3 mg/kg. LK-732 is used in cardiovascular and cerebrovascular research.</p>
    Formula:C25H29N5O3S
    Color and Shape:Solid
    Molecular weight:479.59
  • SAR107375

    CAS:
    <p>SAR107375 is a potent, orally active dual inhibitor of thrombin and factor Xa, with K_i values of 1 nM and 8 nM for factor Xa and thrombin, respectively [1].</p>
    Formula:C24H30ClN5O5S2
    Color and Shape:Solid
    Molecular weight:568.11
  • Antiplatelet agent 3

    CAS:
    <p>Antiplatelet agent 3 (Compound K-10) is a compound with antiplatelet aggregation activity, exhibiting IC50 values of 2.55, 3.22, and 2.09 mg/mL for platelet aggregation induced by ADP, AA, and COL, respectively. It holds potential for research in cardiovascular diseases.</p>
    Formula:C38H32N2O5
    Color and Shape:Solid
    Molecular weight:596.671