Serine/threonin kinase
Serine/threonine kinase inhibitors are compounds that target enzymes responsible for phosphorylating serine and threonine residues on proteins, which play a pivotal role in regulating apoptosis and other cellular processes. These kinases are involved in signaling pathways that control cell growth, division, and programmed cell death. Inhibiting specific serine/threonine kinases can alter the balance between cell survival and apoptosis, making these inhibitors essential tools in cancer research and other areas of cell biology. At CymitQuimica, we provide a comprehensive selection of high-quality serine/threonine kinase inhibitors to support your research in apoptosis, signal transduction, and disease mechanisms.
Found 23 products for "Serine/threonin kinase".
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CRA-2059
CAS:CRA-2059 is a selective and reversible inhibitor of human tryptase beta, exhibiting a Ki value of 620 pM against recombinant human tryptase beta (rHTβ).Formula:C34H46N12O8Purity:97.68% - 99.29%Color and Shape:White SolidMolecular weight:750.82MARK4 inhibitor 3
MARK4 inhibitor 3 is a selective MARK4 inhibitor (IC₅₀=1.01 μM) that suppresses cancer cell proliferation for cancer and neurodegeneration studies.Formula:C33H27FN4O3Purity:99.47%Color and Shape:SolidMolecular weight:546.59MASTL-IN-2
CAS:MASTL-IN-2 is a MASTL kinase inhibitor. MASTL-IN-2 inhibits MIA PaCa pancreatic cancer cell proliferation with an IC50 of 2.8 nM.Formula:C21H25N7O2Color and Shape:Odour SolidMolecular weight:407.471,8-Diazanaphthalene
CAS:1,8-Diazanaphthalene inhibits Protein Kinase B with a binding constant Ka=407 μM.Formula:C8H6N2Color and Shape:SolidMolecular weight:130.1466Tilpisertib
CAS:Tilpisertib is a serine/threonine kinase inhibitor (WO2017007689).Formula:C33H33ClN8OPurity:99.88%Color and Shape:SolidMolecular weight:593.121SGC-GAK-1
CAS:SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM).Formula:C18H17BrN2O3Purity:99.85%Color and Shape:Yellow SolidMolecular weight:389.243PKD-IN-1
CAS:CRT0066101 is an inhibitor of PKD.Formula:C18H19ClN4OPurity:98%Color and Shape:SolidMolecular weight:342.82kb NB 142-70
CAS:kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).Formula:C11H9NO2S2Purity:98.01% - ≥95%Color and Shape:SolidMolecular weight:251.32CID755673
CAS:CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.Formula:C12H11NO3Purity:97.68% - 99.84%Color and Shape:SolidMolecular weight:217.2206MLCK inhibitor peptide 18 acetate
MLCK inhibitor peptide 18 acetate: Selective (IC50=50nM), 4000x more than CaM kinase II. Does not block PKA. Cell-permeable.Formula:C62H109N23O13Purity:99.90%Color and Shape:SolidMolecular weight:1384.67SRPIN340
CAS:SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).Formula:C18H18F3N3OPurity:99.79% - 99.96%Color and Shape:White SolidMolecular weight:349.35CID 2011756
CAS:CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.Formula:C22H21ClN2O3Purity:98.15% - ≥95%Color and Shape:SolidMolecular weight:396.867SPHINX31
CAS:SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Formula:C27H24F3N5O2Purity:99.3% - 99.87%Color and Shape:SolidMolecular weight:507.507GAK inhibitor 49
CAS:GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).Formula:C20H22N2O5Purity:98.71%Color and Shape:SolidMolecular weight:370.39911-Naphthyl PP1
CAS:1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Formula:C19H19N5Purity:99.85%Color and Shape:SolidMolecular weight:317.39TLK1-IN-1
TLK1-IN-1 (Compound 5n) is a TLK1 inhibitor with an IC50 of 7.2 μM for TLK1B and a GI50 of 2.7 μM for LNCaP cells. It induces DNA damage and apoptosis (Apoptosis) in cancer cells and is applicable in prostate cancer research.Formula:C24H23BrClN5O3Color and Shape:SolidMolecular weight:544.83SRPKIN-1
CAS:SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).Formula:C27H21FN2O3SPurity:98%Color and Shape:SolidMolecular weight:472.531Ofirnoflastum
CAS:Ofirnoflastum (Ofirnoflast) is a selective serine/threonine-protein kinase Nek7 inhibitor that exerts potent anti-inflammatory effects by suppressing Nek7-dependent NLRP3 inflammasome activation, reducing caspase-1 cleavage, IL-1β and IL-18 secretion, and pyroptotic cell death in vitro, while significantly attenuating cytokine production and tissue injury in animal models of acute and chronic inflammation, supporting its therapeutic potential in autoimmune and inflammatory diseases.Formula:C23H19F4N7O2Purity:99.81% - 99.87%Color and Shape:SolidMolecular weight:501.44MKI-3
CAS:MKI-3 is a highly selective MASTL inhibitor with a quinazoline scaffold (IC50 5.72 nM), can inhibit ENSA phosphorylation and activate PP2A, and exhibits antiproliferative and in vivo antitumor activity in breast cancer models.Formula:C21H19N7OPurity:97.02%Molecular weight:385.423-IN-PP1
CAS:3-IN-PP1 is a potent inhibitor of PKD1, PKD2, and PKD3 (IC50 = 108, 94, and 108 nM, respectively), acting as a broad-spectrum anticancer agent.Formula:C17H18N6Color and Shape:SolidMolecular weight:306.365
