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Caspase

Caspase

Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.

Found 125 products of "Caspase"

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  • PHYTOSPHINGOSINE
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    PHYTOSPHINGOSINE

    CAS:
    <p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>
    Formula:C18H39NO3
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:317.51

    Ref: TM-T9503

  • TC11
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    TC11

    CAS:
    <p>TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis</p>
    Formula:C20H22N2O2
    Purity:97.86%
    Color and Shape:Solid
    Molecular weight:322.4

    Ref: TM-T9083

  • Belnacasan
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    Belnacasan

    CAS:
    <p>Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.</p>
    Formula:C24H33ClN4O6
    Purity:96.53% - 99.5%
    Color and Shape:Solid
    Molecular weight:508.99

    Ref: TM-T6090

  • Sesamolin
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    Sesamolin

    CAS:
    <p>Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.</p>
    Formula:C20H18O7
    Purity:98.77% - 99.04%
    Color and Shape:Solid
    Molecular weight:370.35

    Ref: TM-T5S2283

  • Wedelolactone
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    Wedelolactone

    CAS:
    <p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>
    Formula:C16H10O7
    Purity:98.07% - 99.87%
    Color and Shape:Solid
    Molecular weight:314.25

    Ref: TM-T3384

  • PI-1840
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    PI-1840

    CAS:
    <p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>
    Formula:C22H26N4O3
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:394.47

    Ref: TM-T6941

  • Dehydrocorydaline
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    Dehydrocorydaline

    CAS:
    <p>1.</p>
    Formula:C22H24NO4
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:366.43

    Ref: TM-T5S2358

  • Daphnetin
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    Daphnetin

    CAS:
    <p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>
    Formula:C9H6O4
    Purity:97.47% - 99.8%
    Color and Shape:Solid
    Molecular weight:178.14

    Ref: TM-T2851

  • Ac-DEVD-pNA
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    Ac-DEVD-pNA

    CAS:
    <p>Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.</p>
    Formula:C26H34N6O13
    Purity:>99.99%
    Color and Shape:White
    Molecular weight:638.58

    Ref: TM-T7816

  • Z-YVAD-FMK
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    Z-YVAD-FMK

    CAS:
    <p>AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.</p>
    Formula:C31H39FN4O9
    Purity:98.00%
    Color and Shape:Solid
    Molecular weight:630.66

    Ref: TM-TP1466

  • Emricasan
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    Emricasan

    CAS:
    <p>Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.</p>
    Formula:C26H27F4N3O7
    Purity:98.13% - 99%
    Color and Shape:Solid
    Molecular weight:569.5

    Ref: TM-T6826

  • Z-FA-FMK
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    Z-FA-FMK

    CAS:
    <p>Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.</p>
    Formula:C21H23FN2O4
    Purity:98.84% - 99.68%
    Color and Shape:Solid
    Molecular weight:386.42

    Ref: TM-T6738

  • Dihydrocapsaicin
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    Dihydrocapsaicin

    CAS:
    <p>Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.</p>
    Formula:C18H29NO3
    Purity:99.61% - ≥95%
    Color and Shape:White Crystal
    Molecular weight:307.43

    Ref: TM-T2163

  • Aristolactam I
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    Aristolactam I

    CAS:
    <p>Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.</p>
    Formula:C17H11NO4
    Purity:98.98% - 99.63%
    Color and Shape:Solid
    Molecular weight:293.27

    Ref: TM-T3S1227

  • Ossirene
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    Ossirene

    CAS:
    <p>Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.</p>
    Formula:C2H4Cl3O2Te·H4N
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:312.05

    Ref: TM-T6761

  • Tauroursodeoxycholate
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    Tauroursodeoxycholate

    CAS:
    <p>Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.</p>
    Formula:C26H45NO6S
    Purity:98.77% - 99.93%
    Color and Shape:White Solid
    Molecular weight:499.7

    Ref: TM-T2532

  • Senkyunolide I
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    Senkyunolide I

    CAS:
    <p>1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.</p>
    Formula:C12H16O4
    Purity:99.73% - 99.88%
    Color and Shape:Solid
    Molecular weight:224.25

    Ref: TM-T5S2076

  • Diclofenac Potassium
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    Diclofenac Potassium

    CAS:
    <p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>
    Formula:C14H10Cl2KNO2
    Purity:99.51%
    Color and Shape:White To Yellowish Crystalline Powder
    Molecular weight:334.24

    Ref: TM-T6470

  • CASP3 Activator 1541
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    CASP3 Activator 1541

    CAS:
    <p>CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.</p>
    Formula:C24H17N3O4
    Purity:98.84%
    Color and Shape:Solid
    Molecular weight:411.41

    Ref: TM-T8652

  • L67
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    L67

    CAS:
    <p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>
    Formula:C16H14Br2N4O4
    Purity:98.34% - 99.56%
    Color and Shape:Solid
    Molecular weight:486.11

    Ref: TM-T3103