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Kinesin

Kinesin

Kinesin inhibitors target kinesin motor proteins, which are responsible for transporting cellular cargo along microtubules and play a key role in cell division, particularly during mitosis. Kinesins are involved in the movement of chromosomes and other organelles during cell division. Inhibiting kinesins can disrupt these processes, leading to cell cycle arrest and potential cell death, making these inhibitors valuable in cancer research. At CymitQuimica, we offer a diverse range of high-quality kinesin inhibitors to support your research in cell biology, mitosis, and cancer therapy.

Found 66 products of "Kinesin"

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  • Paprotrain
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    Paprotrain

    CAS:
    <p>Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.</p>
    Formula:C16H11N3
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:245.28

    Ref: TM-T12359

  • BOS-172722
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    BOS-172722

    CAS:
    <p>BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).</p>
    Formula:C24H30N8O
    Purity:99.37%
    Color and Shape:Solid
    Molecular weight:446.55

    Ref: TM-T14765

  • Mps1-IN-3
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    Mps1-IN-3

    CAS:
    <p>Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).</p>
    Formula:C26H31N7O4S
    Purity:99.25%
    Color and Shape:Solid
    Molecular weight:537.63

    Ref: TM-T16130

  • KIF18A-IN-16
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    KIF18A-IN-16

    CAS:
    <p>KIF18A-IN-16 (Compound 15) is a polycyclic KIF18A inhibitor. It is applicable in research related to tumors, including colon cancer, breast cancer, and lung cancer.</p>
    Formula:C30H37N5O4S
    Color and Shape:Solid
    Molecular weight:563.71

    Ref: TM-T203421

  • KIF18A-IN-15
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    KIF18A-IN-15

    CAS:
    <p>KIF18A-IN-15 (Compound Example 36) is a KIF18A inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, both with an IC50 range of 0.01-0.1 μM. These compounds inhibit the viability of OVCAR-3 cells, with IC50 values of 0.01-0.1 μM for EX36-A and 0-0.01 μM for EX36-B. KIF18A-IN-15 is applicable in research on tumors, including colon, breast, and lung cancers.</p>
    Formula:C25H33F3N6O5S
    Color and Shape:Solid
    Molecular weight:586.63

    Ref: TM-T203212

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    KIF2C-IN-1

    <p>KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.</p>
    Formula:C36H39ClN4O9S
    Color and Shape:Solid
    Molecular weight:738.21263

    Ref: TM-T207280

  • KIF18A-IN-14
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    KIF18A-IN-14

    CAS:
    <p>KIF18A-IN-14 (Compound Example 81) is an inhibitor of KIF18A that exists in two forms, EX81-A and its enantiomer EX81-B. EX81-A and EX81-B inhibit the viability of OVCAR-3 cells with IC50 values of 0-0.01 μM and 0.01-0.1 μM, respectively. KIF18A-IN-14 can be utilized in tumor research, including studies on colon cancer, breast cancer, and lung cancer.</p>
    Formula:C26H32F3N5O6S
    Color and Shape:Solid
    Molecular weight:599.62

    Ref: TM-T203056

  • Solidagonic acid
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    Solidagonic acid

    CAS:
    <p>Solidagonic acid inhibits HSET, prevents fission yeast cell death, and hinders L. sativa and L. multiflorum seedling growth.</p>
    Formula:C22H34O4
    Color and Shape:Solid
    Molecular weight:362.5

    Ref: TM-T75576

  • 11H-Benzo[a]carbazole
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    11H-Benzo[a]carbazole

    CAS:
    <p>11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.</p>
    Formula:C16H11N
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:217.27

    Ref: TM-TN9686

  • CymitQuimica logo
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    Mps1-IN-6

    <p>Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].</p>
    Formula:C35H39N9O3
    Color and Shape:Solid
    Molecular weight:633.74

    Ref: TM-T78965

  • Eg5-IN-1
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    Eg5-IN-1

    <p>Eg5-IN-1 is a potent inhibitor of the kinesin family of motor proteins (Eg5) with an IC50 value of 1.97 µM for Eg5.Eg5-IN-1 can be used in cancer research.</p>
    Formula:C23H16ClFN4O
    Purity:98.21%
    Color and Shape:Solid
    Molecular weight:418.85

    Ref: TM-T77586

  • Filanesib TFA
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    Filanesib TFA

    CAS:
    <p>Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.</p>
    Formula:C22H23F5N4O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:534.5

    Ref: TM-T25418

  • (S)-Monastrol
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    (S)-Monastrol

    CAS:
    <p>Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>
    Formula:C14H16N2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:292.35

    Ref: TM-T4649

  • GW406108X
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    GW406108X

    CAS:
    <p>GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.</p>
    Formula:C20H11Cl2NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:400.21

    Ref: TM-T9207

  • AZ82
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    AZ82

    CAS:
    <p>AZ82 is an inhibitor of the kinesin-like protein KIFC1, which induces multipolar mitosis and apoptosis in prostate cancer cells.</p>
    Formula:C28H31F3N4O3S
    Purity:99.31%
    Color and Shape:Solid
    Molecular weight:560.63

    Ref: TM-T10428

  • Kinesore
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    Kinesore

    CAS:
    <p>Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.</p>
    Formula:C20H16Br2N4O4
    Purity:97.24%
    Color and Shape:Solid
    Molecular weight:536.17

    Ref: TM-T15663

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    Mps1-IN-3 hydrochloride

    <p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>
    Formula:C26H32ClN7O4S
    Color and Shape:Solid
    Molecular weight:574.09

    Ref: TM-T64061

  • Mps1-IN-1 dihydrochloride
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    Mps1-IN-1 dihydrochloride

    CAS:
    <p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>
    Formula:C28H35Cl2N5O4S
    Color and Shape:Solid
    Molecular weight:608.58

    Ref: TM-T70095

  • SB-743921 hydrochloride
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    SB-743921 hydrochloride

    CAS:
    <p>SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).</p>
    Formula:C31H34Cl2N2O3
    Purity:95.58% - 99.70%
    Color and Shape:Solid
    Molecular weight:553.52

    Ref: TM-T2255

  • GW406108X(Z/E)
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    GW406108X(Z/E)

    CAS:
    <p>GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .</p>
    Formula:C20H11Cl2NO4
    Purity:98.23%
    Color and Shape:Solid
    Molecular weight:400.21

    Ref: TM-T9207L