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Kinesin

Kinesin

Kinesin inhibitors target kinesin motor proteins, which are responsible for transporting cellular cargo along microtubules and play a key role in cell division, particularly during mitosis. Kinesins are involved in the movement of chromosomes and other organelles during cell division. Inhibiting kinesins can disrupt these processes, leading to cell cycle arrest and potential cell death, making these inhibitors valuable in cancer research. At CymitQuimica, we offer a diverse range of high-quality kinesin inhibitors to support your research in cell biology, mitosis, and cancer therapy.

Found 89 products for "Kinesin".

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  • Monastrol

    CAS:
    Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
    Formula:C14H16N2O3S
    Purity:98.02% - 98.59%
    Color and Shape:Solid
    Molecular weight:292.353
  • Dimethylenastron

    CAS:
    Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.
    Formula:C16H18N2O2S
    Purity:97.81%
    Color and Shape:Solid
    Molecular weight:302.39
  • ARQ 621

    CAS:
    ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
    Formula:C28H24Cl2FN5O2
    Purity:97.93% - 98.38%
    Color and Shape:Yellow Solid
    Molecular weight:552.427
  • Mps1-IN-2

    CAS:
    Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.
    Formula:C26H36N6O3
    Purity:96.24% - 99.75%
    Color and Shape:Yellow Solid
    Molecular weight:480.6024
  • Mps1-IN-1

    CAS:
    Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )
    Formula:C28H33N5O4S
    Purity:99.55%
    Color and Shape:Yellow Solid
    Molecular weight:535.658
  • BAY1217389

    CAS:
    BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).
    Formula:C27H24F5N5O3
    Purity:98.14% - 99.04%
    Color and Shape:White Solid
    Molecular weight:561.5032
  • EMD534085

    CAS:
    EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).
    Formula:C25H31F3N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:476.5344
  • CK0106023

    CAS:
    CK0106023, a KSP inhibitor, shows strong antitumor effects in mice, outperforming paclitaxel, and induces monopolar spindles.
    Formula:C30H32BrClN4O2
    Color and Shape:Solid
    Molecular weight:595.96
  • PF-2771

    CAS:
    PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.
    Formula:C29H36ClN5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:554.08
  • TC-Mps1-12

    CAS:
    TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
    Formula:C17H20N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.38
  • KIF18A-IN-3

    CAS:
    KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.
    Formula:C28H38N4O5S2
    Purity:98.45%
    Color and Shape:Yellow Solid
    Molecular weight:574.755
  • Kif15-IN-1

    CAS:
    Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.
    Formula:C20H22N4O5S
    Purity:99.39% - 99.39%
    Color and Shape:Solid
    Molecular weight:430.477
  • Litronesib Racemate

    CAS:
    Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.
    Formula:C23H37N5O4S2
    Color and Shape:Solid
    Molecular weight:511.701
  • SR31527

    CAS:
    SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.
    Formula:C15H14ClN3OS
    Purity:98.52%
    Color and Shape:Yellow Solid
    Molecular weight:319.81
  • Eg5 Inhibitor V, trans-24

    CAS:
    Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.
    Formula:C26H21N3O3
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:423.4632
  • AM-5308

    CAS:
    AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.
    Formula:C26H35N5O5S
    Purity:98.95% - 99.58%
    Color and Shape:Solid
    Molecular weight:529.652
  • Syntelin

    CAS:
    Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.
    Formula:C21H20N6O2S3
    Color and Shape:Solid
    Molecular weight:484.617
  • CFI-400936

    CAS:
    CFI-400936: potent TTK inhibitor (IC50=3.6nM), potential anticancer, active in cell assays, selective vs. human kinases.
    Formula:C25H27N5O3S
    Color and Shape:Solid
    Molecular weight:477.58
  • Mps-BAY2b

    CAS:
    Mps-BAY2b is a novel MPS1 inhibitor.
    Formula:C20H23N5O
    Color and Shape:Solid
    Molecular weight:349.43
  • HR22C16

    CAS:
    HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.
    Formula:C23H23N3O3
    Color and Shape:Solid
    Molecular weight:389.45