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Kinesin

Kinesin

Kinesin inhibitors target kinesin motor proteins, which are responsible for transporting cellular cargo along microtubules and play a key role in cell division, particularly during mitosis. Kinesins are involved in the movement of chromosomes and other organelles during cell division. Inhibiting kinesins can disrupt these processes, leading to cell cycle arrest and potential cell death, making these inhibitors valuable in cancer research. At CymitQuimica, we offer a diverse range of high-quality kinesin inhibitors to support your research in cell biology, mitosis, and cancer therapy.

Found 66 products of "Kinesin"

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  • S-trityl-L-Cysteine

    CAS:
    <p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>
    Formula:C22H21NO2S
    Purity:97.02%
    Color and Shape:Almost White To Light Yellow Granular Powder
    Molecular weight:363.47
  • CW-069

    CAS:
    <p>CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>
    Formula:C23H21IN2O3
    Purity:97.52% - 99.52%
    Color and Shape:Solid
    Molecular weight:500.33
  • SB-743921 hydrochloride

    CAS:
    <p>SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).</p>
    Formula:C31H34Cl2N2O3
    Purity:95.58% - 99.70%
    Color and Shape:Solid
    Molecular weight:553.52
  • Mps1-IN-3 hydrochloride


    <p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>
    Formula:C26H32ClN7O4S
    Color and Shape:Solid
    Molecular weight:574.09
  • Mps1-IN-1 dihydrochloride

    CAS:
    <p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>
    Formula:C28H35Cl2N5O4S
    Color and Shape:Solid
    Molecular weight:608.58
  • Ispinesib

    CAS:
    <p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>
    Formula:C30H33ClN4O2
    Purity:98% - 99.09%
    Color and Shape:Solid
    Molecular weight:517.06
  • GSK-923295

    CAS:
    <p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>
    Formula:C32H38ClN5O4
    Purity:96.22% - 98.02%
    Color and Shape:Solid
    Molecular weight:592.13
  • BTB-1

    CAS:
    <p>BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.</p>
    Formula:C12H8ClNO4S
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:297.71
  • Sovilnesib

    CAS:
    <p>Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.</p>
    Formula:C26H34F2N6O4S
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:564.65
  • K858 (Racemic)

    CAS:
    <p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>
    Formula:C13H15N3O2S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:277.34
  • Monastrol

    CAS:
    <p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>
    Formula:C14H16N2O3S
    Purity:98.02% - 98.59%
    Color and Shape:Solid
    Molecular weight:292.35
  • Dimethylenastron

    CAS:
    <p>Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.</p>
    Formula:C16H18N2O2S
    Purity:98.07%
    Color and Shape:Solid
    Molecular weight:302.39
  • ARQ 621

    CAS:
    <p>ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.</p>
    Formula:C28H24Cl2FN5O2
    Purity:97.01% - 98.38%
    Color and Shape:Solid
    Molecular weight:552.43
  • Mps1-IN-2

    CAS:
    <p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>
    Formula:C26H36N6O3
    Purity:96.24% - 99.75%
    Color and Shape:Solid
    Molecular weight:480.6
  • Mps1-IN-1

    CAS:
    <p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>
    Formula:C28H33N5O4S
    Purity:98.33%
    Color and Shape:Solid
    Molecular weight:535.66
  • BAY1217389

    CAS:
    <p>BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50&lt;10 nM).</p>
    Formula:C27H24F5N5O3
    Purity:98.14% - 99.42%
    Color and Shape:Solid
    Molecular weight:561.5
  • SR31527

    CAS:
    <p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability &amp; colony growth.</p>
    Formula:C15H14ClN3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.81
  • Eg5 Inhibitor V, trans-24

    CAS:
    <p>Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.</p>
    Formula:C26H21N3O3
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:423.46
  • Litronesib Racemate

    CAS:
    <p>Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.</p>
    Formula:C23H37N5O4S2
    Color and Shape:Solid
    Molecular weight:511.7
  • Syntelin

    CAS:
    <p>Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.</p>
    Formula:C21H20N6O2S3
    Color and Shape:Solid
    Molecular weight:484.62