Kinesin
Kinesin inhibitors target kinesin motor proteins, which are responsible for transporting cellular cargo along microtubules and play a key role in cell division, particularly during mitosis. Kinesins are involved in the movement of chromosomes and other organelles during cell division. Inhibiting kinesins can disrupt these processes, leading to cell cycle arrest and potential cell death, making these inhibitors valuable in cancer research. At CymitQuimica, we offer a diverse range of high-quality kinesin inhibitors to support your research in cell biology, mitosis, and cancer therapy.
Found 86 products for "Kinesin".
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Mps1-IN-6
Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].Formula:C35H39N9O3Color and Shape:SolidMolecular weight:633.74Eg5-IN-3
Eg5-IN-3 (5) is an Eg5 inhibitor targeting a novel allosteric site (α4/α6/L11). It disrupts tubulin assembly, leading to abnormal and irregular formations, which subsequently causes typical mitotic arrest, akin to the effects of Monastrol.Formula:C23H23N7O2Color and Shape:SolidMolecular weight:429.19132Filanesib TFA
CAS:Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.Formula:C22H23F5N4O4SPurity:98%Color and Shape:SolidMolecular weight:534.5GW406108X
CAS:GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Formula:C20H11Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:400.21AZ82
CAS:AZ82 is an inhibitor of the kinesin-like protein KIFC1, which induces multipolar mitosis and apoptosis in prostate cancer cells.Formula:C28H31F3N4O3SPurity:99.31%Color and Shape:SolidMolecular weight:560.63Kinesore
CAS:Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Formula:C20H16Br2N4O4Purity:97.24%Color and Shape:Gray SolidMolecular weight:536.17Ref: TM-T15663
2mg39.00€5mg58.00€1mL*10mM (DMSO)70.00€10mg93.00€25mg150.00€50mg219.00€100mg329.00€200mg494.00€Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Formula:C16H18N2O2SPurity:97.81%Color and Shape:SolidMolecular weight:302.39Ref: TM-T3118
1mg34.00€2mg46.00€5mg58.00€1mL*10mM (DMSO)64.00€10mg93.00€25mg147.00€50mg222.00€100mg334.00€ARQ 621
CAS:ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.Formula:C28H24Cl2FN5O2Purity:97.01% - 98.38%Color and Shape:SolidMolecular weight:552.43BRD9876
CAS:BRD9876 is a selective inhibitor of MM1S growth.Formula:C16H14N2Purity:97.81%Color and Shape:SolidMolecular weight:234.3Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurity:98.02% - 98.59%Color and Shape:SolidMolecular weight:292.35Ref: TM-T4048
1mg46.00€5mg73.00€1mL*10mM (DMSO)81.00€10mg92.00€25mg178.00€50mg295.00€100mg477.00€500mg1,018.00€AZ3146
CAS:AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.Formula:C24H32N6O3Purity:97.84% - >99.99%Color and Shape:White SolidMolecular weight:452.55K858 (Racemic)
CAS:K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formula:C13H15N3O2SPurity:99.95%Color and Shape:SolidMolecular weight:277.34Mps1-IN-3 hydrochloride
Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.Formula:C26H32ClN7O4SColor and Shape:SolidMolecular weight:574.09SB-743921 hydrochloride
CAS:SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).Formula:C31H34Cl2N2O3Purity:95.58% - 99.70%Color and Shape:White SolidMolecular weight:553.52Ref: TM-T2255
1mg39.00€5mg101.00€1mL*10mM (DMSO)123.00€10mg155.00€25mg263.00€50mg406.00€100mg622.00€500mg1,423.00€CW-069
CAS:CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Formula:C23H21IN2O3Purity:97.52% - 99.52%Color and Shape:SolidMolecular weight:500.33Ref: TM-T6209
1mg40.00€5mg86.00€1mL*10mM (DMSO)94.00€10mg118.00€25mg205.00€50mg290.00€100mg409.00€500mg888.00€S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Formula:C22H21NO2SPurity:97.08%Color and Shape:SolidMolecular weight:363.47GSK-923295
CAS:GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).Formula:C32H38ClN5O4Purity:96.22% - 98.02%Color and Shape:White SolidMolecular weight:592.13Ref: TM-T2039
1mg50.00€5mg92.00€1mL*10mM (DMSO)129.00€10mg165.00€25mg268.00€50mg409.00€100mg573.00€200mg807.00€Empesertib
CAS:Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Formula:C29H26FN5O4SPurity:97.45% - 99.4%Color and Shape:SolidMolecular weight:559.61Sovilnesib
CAS:Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.Formula:C26H34F2N6O4SPurity:99.57%Color and Shape:White SolidMolecular weight:564.65Ref: TM-T39994
1mg90.00€5mg222.00€1mL*10mM (DMSO)245.00€10mg356.00€25mg597.00€50mg850.00€100mg1,153.00€Ispinesib
CAS:Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplasticFormula:C30H33ClN4O2Purity:98% - 99.09%Color and Shape:White SolidMolecular weight:517.06Ref: TM-T2103
2mg46.00€5mg74.00€1mL*10mM (DMSO)85.00€10mg112.00€25mg200.00€50mg320.00€100mg528.00€200mg755.00€
