Integrin
Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.
Found 224 products of "Integrin"
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Abituzumab
CAS:<p>Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.</p>Purity:>95%Color and Shape:LiquidElarofiban TFA
CAS:<p>Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.</p>Formula:C26H34F6N4O8Purity:99.08%Color and Shape:SoildMolecular weight:644.56Teplizumab
CAS:<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Purity:SDS-PAGE:95.8%;SEC-HPLC:99.7%Color and Shape:LiquidMolecular weight:145.79 kDaAbciximab
CAS:<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaAbrilumab
CAS:<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Purity:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Color and Shape:LiquidRWJ 50271
CAS:<p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>Formula:C18H17F3N4O2SPurity:99.09%Color and Shape:SolidMolecular weight:410.41Efalizumab
CAS:<p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>Purity:SDS-PAGE:95% SEC-HPLC:98.77%Color and Shape:LiquidMolecular weight:146.14 kDaVedolizumab
CAS:<p>Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.</p>Purity:SDS-PAGE:98.4%;SEC-HPLC:99.1%Color and Shape:LiquidMolecular weight:146.80 kDaATN-161 trifluoroacetate salt
CAS:<p>ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.</p>Formula:C25H36F3N9O10SPurity:98% - 99.98%Color and Shape:SolidMolecular weight:711.67Tadocizumab
CAS:<p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>Purity:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Color and Shape:LiquidOrbofiban TFA
CAS:<p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>Formula:C19H24F3N5O6Purity:97.21% - 98.72%Color and Shape:SolidMolecular weight:475.42Foralumab
CAS:<p>Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.</p>Purity:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Color and Shape:LiquidOtelixizumab
CAS:<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Purity:>95%Color and Shape:LiquidTidutamab
CAS:<p>Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).</p>Purity:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Color and Shape:LiquidCibisatamab
CAS:<p>Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.</p>Purity:SDS-PAGE:99.1%;SEC-HPLC:96.5%Color and Shape:LiquidMolecular weight:191.1 kDaBersanlimab
CAS:<p>Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.</p>Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:144.22 kDaSMS 121
CAS:<p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>Formula:C20H21NO5Purity:98.29%Color and Shape:SoildMolecular weight:355.38DSPE-PEG5000-cRGD
<p>DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.</p>Color and Shape:Odour SolidLDV FITC
CAS:<p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>Formula:C69H81N11O17SPurity:98%Color and Shape:SolidMolecular weight:1368.53Bimosiamose
CAS:<p>Bimosiamose has anti-inflammatory effects[1].</p>Formula:C46H54O16Purity:98%Color and Shape:SolidMolecular weight:862.91Gantofiban
CAS:<p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>Formula:C21H29N5O6Purity:99.57%Color and Shape:SolidMolecular weight:447.48PLN-1474
CAS:<p>PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.</p>Formula:C24H37N3O4Purity:99.92%Color and Shape:SoildMolecular weight:431.57DSPE-PEG3000-iRGD
<p>DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.</p>Color and Shape:Odour SolidTC113
<p>TC113, a c(RGDyK)-linked Gemcitabine, targets αvβ3 integrin, entering A549 cells, and inhibits WM266.4 and A549 cell growth.</p>Formula:C37H50F2N12O13Color and Shape:SolidMolecular weight:908.86αVβ8-IN-1
CAS:<p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>Formula:C25H32ClN5O4Color and Shape:SolidMolecular weight:502.012-Methylbutyrylcarnitine chloride
<p>2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.</p>Formula:C12H24ClNO4Color and Shape:SolidMolecular weight:281.78Catumaxomab
CAS:<p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>Purity:95%Color and Shape:LiquidGRGDSP
CAS:<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Formula:C22H37N9O10Purity:98%Color and Shape:SolidMolecular weight:587.58AB-3PRGD2
CAS:<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Formula:C137H215IN30O45SColor and Shape:SolidMolecular weight:3161.32Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Formula:C25H41N11O8SColor and Shape:SolidMolecular weight:655.727Mumefural
CAS:<p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>Formula:C12H12O9Color and Shape:SolidMolecular weight:300.22Anti-EMMPRIN/CD147 Antibody
<p>Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Color and Shape:Odour LiquidDSPE-PEG2000-iRGD
<p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>Color and Shape:Odour SolidDSPE-PEG2000-cRGD
<p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>Color and Shape:Odour SolidDSPE-PEG1000-cRGD
<p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>Color and Shape:Odour SolidFibronectin CS1 Peptide
CAS:<p>Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.</p>Formula:C38H64N8O15Purity:98%Color and Shape:SolidMolecular weight:872.96huATN-658
<p>huATN-658 (MNPR-101) is a humanized monoclonal antibody inhibitor targeting the urokinase-type plasminogen activator receptor (uPAR). It effectively disrupts the interaction between uPAR and integrins, thereby inhibiting tumor cell proliferation, invasion, and migration. huATN-658 shows potential for research in breast cancer, particularly in cases of triple-negative breast cancer.</p>Color and Shape:Odour Liquidc(phg-isoDGR-(NMe)k) TFA
<p>C(phg-isoDGR-(NMe)k) TFA is a selective and potent ligand for α5β1-integrin, exhibiting an IC50 of 2.9 nM [1].</p>Formula:C29H42F3N9O9Color and Shape:SolidMolecular weight:717.69LXY3
CAS:<p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>Formula:C32H43N11O15S2Color and Shape:SolidMolecular weight:885.88STX-100
<p>PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.</p>Purity:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:Odour LiquidEtrolizumab
CAS:<p>MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.</p>Purity:98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)Color and Shape:LiquidObtustatin
<p>Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.</p>Formula:C184H284N52O57S8Purity:98%Color and Shape:SolidMolecular weight:4393.07Fuzapladib
CAS:<p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>Formula:C15H20F3N3O3SPurity:99.87%Color and Shape:SoildMolecular weight:379.4Echistatin
CAS:<p>Potent αVβ3 integrin blocker, stops osteoclast binding & bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).</p>Formula:C217H341N71O74S9Purity:98%Color and Shape:SolidMolecular weight:5417.1PDI-IN-4
<p>PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.</p>Formula:C17H12F3NO2Color and Shape:SolidMolecular weight:319.278DSPE-PEG1000-iRGD
<p>DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the αv-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to αv-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.</p>Color and Shape:Odour SolidHSDVHK-NH2
CAS:<p>Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.</p>Formula:C30H48N12O9Purity:98%Color and Shape:SolidMolecular weight:720.78Gly-Arg-Gly-Asp-Ser
CAS:<p>Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.</p>Formula:C17H30N8O9Purity:98%Color and Shape:SolidMolecular weight:490.47α2β1 Integrin Ligand Peptide
CAS:<p>The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular</p>Formula:C14H22N4O9Purity:98%Color and Shape:SolidMolecular weight:390.35K34c hydrochloride
CAS:<p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>Formula:C26H30ClN3O4Purity:99.76% - 99.89%Color and Shape:SoildMolecular weight:483.99Fradafiban hydrochloride
<p>Fradafiban (BIBU-52) is a nonpeptide GPIIb/IIIa antagonist with Kd 148 nM for human platelets.</p>Formula:C20H22ClN3O4Color and Shape:SolidMolecular weight:403.86Dafsolimab
CAS:<p>Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is</p>Color and Shape:LiquidBesufetamig
CAS:<p>Besufetamig is a bispecific antibody targeting programmed cell death protein 1 (PD-1) and the CD3ε chain. It modulates immune cell activity, exerting both immunosuppressive and antitumor effects. Besufetamig holds promise for cancer research.</p>Color and Shape:Liquidαvβ5 integrin-IN-1
CAS:<p>αvβ5 integrin-IN-1, a potent and selective αvβ5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2.</p>Formula:C25H28F3N3O3Color and Shape:SolidMolecular weight:475.512LDV
CAS:<p>α4β1 integrin (VLA-4) ligand (Kd ~ 12 nM). Non-fluorescent derivative of LDV FITC.</p>Formula:C48H70N10O12Purity:98%Color and Shape:SolidMolecular weight:979.13Odulimomab
CAS:<p>Odulimomab: anti-LFA-1 antibody, inhibits T cell growth, protects against ischemic injury, used in transplant rejection research.</p>Color and Shape:Liquidα2β1 Integrin Ligand Peptide TFA
<p>α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is a</p>Formula:C16H23F3N4O11Purity:98%Color and Shape:SolidMolecular weight:504.37Echistatin TFA
<p>Echistatin TFA: a minimal RGD protein from snake venom; inhibits platelet aggregation and bone resorption; targets αIIbβ3, αvβ3, α5β1.</p>Color and Shape:Odour SolidOrbofiban acetate
CAS:<p>Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered</p>Formula:C19H27N5O6Color and Shape:SolidMolecular weight:421.45R-BC154 acetate
<p>R-BC154 acetate: selective α9β1 antagonist, high-affinity integrin probe for α9β1/α4β1 activity study.</p>Formula:C56H65N9O14S3Color and Shape:SolidMolecular weight:1184.36EMD527040
CAS:<p>EMD527040 is a potent αvβ6 antagonist with antifibrotic effects, used in carcinoma and liver fibrosis research.</p>Formula:C29H32Cl2N4O5Color and Shape:SolidMolecular weight:587.5BIO5192 hydrate
<p>BIO5192 hydrate: potent α4β1 inhibitor, binds selectively (Kd<10 pM, IC50=1.8 nM), boosts murine HSPC mobilization 30x.</p>Color and Shape:SolidGanodermaones B
<p>Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression .</p>Formula:C21H26O5Color and Shape:SolidMolecular weight:358.43KGDS
CAS:<p>KGDS is a synthetic peptide that targets the integrin GPIIb-IIIa on the membrane of activated human platelets, with the amino acid sequence Lys-Gly-Asp-Ser [1].</p>Formula:C15H27N5O8Color and Shape:SolidMolecular weight:405.4Lys-Gln-Ala-Gly-Asp-Val
CAS:<p>KQAGDV is a fibrinogen γ-chain cell adhesion peptide, targeting α2bβ3 integrin, and binds SMCs.</p>Formula:C25H44N8O10Color and Shape:SolidMolecular weight:616.66GRGDSPK TFA
<p>GRGDSPK TFA is an RGD peptide, competitive inhibitor of integrin-fibronectin, used to research integrins in bone dynamics.</p>Formula:C30H50F3N11O13Color and Shape:SolidMolecular weight:829.78Integrin Binding Peptide
CAS:<p>Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.</p>Formula:C42H63N15O16SColor and Shape:SolidMolecular weight:1066.12MS133
<p>MS133 is a human bispecific antibody targeting CD133/PROM1 and CD3E. It is used in the study of colon cancer.</p>Color and Shape:Odour LiquidRTDLDSLRTYTL
CAS:<p>RTDLDSLRTYTL is a high-affinity and specific inhibitor of Alpha (v) beta (6) integrin (avb6). By binding to the avb6 integrin, this peptide sequence activates T cell cytotoxicity and cytokine production, such as interferon-γ. Through the design of chimeric T cell antigen receptors (CAR), RTDLDSLRTYTL enables T cells to be redirected, allowing them to specifically recognize and attack tumor cells. It is used in research for cancer immunotherapy and the development of targeted drugs.</p>Formula:C62H104N18O22Color and Shape:SolidMolecular weight:1453.60HSDVHK-NH2 TFA
<p>HSDVHK-NH2 TFA acts as an antagonist to the αvβ3-vitronectin integrin interaction, displaying an inhibitory concentration (IC 50) of 1.74 pg/mL (2.414 pM) [1] [</p>Formula:C32H49F3N12O11Color and Shape:SolidMolecular weight:834.8Forimtamig
<p>Forimtamig (RG-6324) is a bispecific antibody that targets GPRC5D and CD3 T cells. It features a 2 + 1 structure, comprising two high-affinity GPRC5D binding segments and one CD3-binding module. Forimtamig is engineered with a P329G LALA mutation in its Fc domain to prevent Fcγ receptor and C1q binding, while maintaining Fc receptor interaction. Its isotype control corresponds to human IgG1 kappa.</p>Color and Shape:Odour LiquidA20FMDV2
CAS:<p>A20FMDV2 is a highly selective αvβ6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for αvβ6 compared to other RGD-directed integrins like αvβ3, αvβ5, and α5β1. This compound can be derived from the foot-and-mouth disease virus and is suitable for radiolabeling, enabling PET imaging of αvβ6 integrin-positive tumors.</p>Formula:C93H163N31O28Color and Shape:SolidMolecular weight:2163.48Anti-GPRC5D Antibody
<p>Anti-GPRC5D Antibody is a humanized IgG1 monoclonal antibody targeting GPRC5D. It serves as the antibody component of the ADC molecule LM-305.</p>Color and Shape:Odour LiquidBimosiamose disodium
CAS:<p>Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin 86 μM; anti-inflammatory.</p>Formula:C46H52Na2O16Purity:98%Color and Shape:SolidMolecular weight:906.88P8RI acetate
<p>P8RI acetate mimics CD31, activates CDP8RI, and suppresses the immune response by restoring CD31 pathway.</p>Formula:C53H81N13O11Purity:98.39%Color and Shape:SolidMolecular weight:1076.29Dentonin TFA
<p>Dentonin TFA (AC-100 TFA) is a short peptide fragment derived from MEPE. It enhances osteogenesis by promoting the adhesion of osteoprogenitor cells and supports the survival of immature adherent cells. Dentonin TFA does not have a significant effect on mature osteoblasts and can be utilized in studies of phosphate homeostasis and bone metabolism.</p>Formula:C109H161F3N30O44Molecular weight:2651.1235LDV-FITC TFA
<p>LDV-FITC TFA is a fluorescent peptide, specifically an FITC-conjugated LDV peptide. This compound binds to the α4β1 integrin with high affinity, displaying a Kd of 0.3 nM in the presence of Mn2+ and 12 nM in its absence, when binding to U937 cells. LDV-FITC TFA is useful for assessing α4β1 integrin affinity.</p>Formula:C69H81N11O17S·xC2HF3O2Lamifiban trifluoroacetate
CAS:<p>Lamifiban trifluoroacetate is an antagonist of the nonpeptide platelet fibrinogen receptor (GPIIb/IIIa).</p>Formula:C26H29F3N4O8Color and Shape:SolidMolecular weight:582.533ICAM-1988
CAS:<p>ICAM-1988 is a LFA-1 antagonist.</p>Formula:C22H22Cl2N4O6SColor and Shape:SolidMolecular weight:541.4Variabilin
CAS:<p>Variabilin is a natural product that can be used as a reference standard. The CAS number of Variabilin is 3187-52-8.</p>Formula:C17H16O5Color and Shape:SolidMolecular weight:300.31Arg-Gly-Glu-Ser
CAS:<p>Arg-Gly-Glu-Ser is a RGD related peptide that is a control for the RGDS activity of fibrinogen binding to activated platelets.</p>Formula:C16H29N7O8Purity:98%Color and Shape:SolidMolecular weight:447.44Risuteganib
CAS:<p>Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.</p>Formula:C22H39N9O11SPurity:98%Color and Shape:SolidMolecular weight:637.66αvβ6-IN-1
<p>αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.</p>Formula:C25H32F2N4O3Color and Shape:SolidMolecular weight:474.54αvβ6-IN-2
<p>αvβ6-IN-2 (compound 20) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 7.8. It shows potential for use in research on idiopathic pulmonary fibrosis.</p>Formula:C25H30F3N3O3Color and Shape:SolidMolecular weight:477.52c(avb6)-DOTA TFA
<p>c(avb6)-DOTA TFA is a conjugate formed by the coupling of a selective αvβ6 integrin cyclic peptide and a DPTA chelating agent. The Lu (III) complex of c(avb6)-DOTA TFA exhibits considerable affinity for αvβ6 integrin (IC50=0.8 nM), making it suitable for tumor diagnostics.</p>Formula:C69H102F3N17O20Color and Shape:SolidMolecular weight:1546.65Indatuximab
<p>Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.</p>Purity:>95%Color and Shape:LiquidMolecular weight:145.5 kDaGRGDSPK
CAS:<p>GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.</p>Formula:C28H49N11O11Purity:98%Color and Shape:SolidMolecular weight:715.76C16Y
CAS:<p>C16Y, a short peptide, serves as an inhibitor for the integrins αvβ3 and α5β1. It targets the cell membrane and exerts its antitumor activity by inhibiting angiogenesis.</p>Formula:C78H115N17O17Color and Shape:SolidMolecular weight:1562.85GSK 3008348 hydrochloride
CAS:<p>GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.</p>Formula:C29H37N5O2xHClPurity:99.54%Color and Shape:SolidMolecular weight:0Azelaoyl PAF
CAS:<p>Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.</p>Formula:C33H66NO9PColor and Shape:SolidMolecular weight:651.85Obtustatin triacetate
<p>Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of the</p>Formula:C184H284N52O57S8·3C2H4O2Purity:99.51%Color and Shape:SolidMolecular weight:4573.21BT100
<p>BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1].</p>Purity:98%Color and Shape:Odour SolidVolociximab
CAS:<p>Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of rabbit VX2 tumors and is used to study solid tumors.</p>Purity:95%Color and Shape:LiquidMK-0429
CAS:<p>MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).</p>Formula:C23H29N5O4Color and Shape:SolidMolecular weight:439.51Cilengitide TFA
CAS:<p>Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.</p>Formula:C29H41F3N8O9Color and Shape:SolidMolecular weight:702.68Anti-Mouse CD3 Antibody (17A2)
<p>Anti-Mouse CD3 Antibody (17A2) is an IgG2b class antibody of murine origin targeting CD3 and can be used to study TCR signaling and antigen recognition.</p>Color and Shape:Odour LiquidLifitegrast sodium
CAS:<p>Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.</p>Formula:C29H23Cl2N2NaO7SPurity:99.33%Color and Shape:SolidMolecular weight:637.46GPRP
CAS:<p>GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.</p>Formula:C18H31N7O5Color and Shape:White To Off-White PowderMolecular weight:425.48RGD Trifluoroacetate
CAS:<p>RGD Trifluoroacetate is a tripeptide for cell adhesion, effective on 24 integrins, and widely used for synthetic surface binding.</p>Formula:C14H23F3N6O8Purity:98%Color and Shape:SoildMolecular weight:460.36Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66A-205804
CAS:<p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>Formula:C15H12N2OS2Purity:98.07% - 98.52%Color and Shape:SolidMolecular weight:300.4Cyclo(-RGDfK)
CAS:<p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>Formula:C27H41N9O7Purity:95.29% - >99.99%Color and Shape:SolidMolecular weight:603.67PND-1186
CAS:<p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>Formula:C25H26F3N5O3Purity:99.14% - 99.75%Color and Shape:SolidMolecular weight:501.5GLPG0187
CAS:<p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>Formula:C29H37N7O5SPurity:99.4% - 99.70%Color and Shape:SolidMolecular weight:595.71OSU-T315
CAS:<p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>Formula:C30H30F3N5OPurity:98.69%Color and Shape:SolidMolecular weight:533.59Arginine-glycine-aspartic acid
CAS:<p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>Formula:C12H22N6O6Purity:99.11%Color and Shape:SolidMolecular weight:346.34Cyclo(RADfK)
CAS:<p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>Formula:C28H43N9O7Purity:>99.99%Color and Shape:SolidMolecular weight:617.7Cyclo(-RGDfK) TFA
CAS:<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Formula:C29H42F3N9O9Purity:98.99% - 99.54%Color and Shape:SolidMolecular weight:717.69CWHM-12
CAS:<p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>Formula:C26H32BrN5O6Purity:98.05% - 99.83%Color and Shape:SolidMolecular weight:590.47H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:<p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>Formula:C23H38N10O10Purity:>99.99%Color and Shape:SolidMolecular weight:614.61iRGD peptide
CAS:<p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>Formula:C35H57N13O14S2Purity:98.77%Color and Shape:SolidMolecular weight:948.04Leukadherin-1
CAS:<p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>Formula:C22H15NO4S2Purity:98.49% - 98.93%Color and Shape:SolidMolecular weight:421.49Pyrintegrin
CAS:<p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>Formula:C23H25N5O3SPurity:99.19%Color and Shape:SolidMolecular weight:451.54Orbofiban
CAS:<p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>Formula:C17H23N5O4Color and Shape:SolidMolecular weight:361.4Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Formula:C32H46O8Purity:97.1% - 99.33%Color and Shape:SolidMolecular weight:558.7ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Formula:C30H30F3N5OPurity:99.30%Color and Shape:SolidMolecular weight:533.59A-286982
CAS:<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Formula:C24H27N3O4SPurity:97.81%Color and Shape:SolidMolecular weight:453.55Arg-Gly-Asp TFA (99896-85-2(free base))
<p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>Formula:C14H23F3N6O8Purity:99.2% - ≥98%Color and Shape:SolidMolecular weight:460.36roxifiban
CAS:<p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>Formula:C21H29N5O6Purity:98%Color and Shape:SolidMolecular weight:447.48LXW7
CAS:<p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>Formula:C29H48N12O12S2Purity:>99.99%Color and Shape:SolidMolecular weight:820.89Natalizumab
CAS:<p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>Purity:98.00%Color and Shape:LiquidMolecular weight:N/ALifitegrast
CAS:<p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>Formula:C29H24Cl2N2O7SPurity:99.39% - 99.66%Color and Shape:SolidMolecular weight:615.48Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Formula:C18H16O8Purity:99.50% - 99.85%Color and Shape:SolidMolecular weight:360.31Carotegrast methyl
CAS:<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Formula:C28H26Cl2N4O5Purity:99.26% - 99.72%Color and Shape:SolidMolecular weight:569.44Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Formula:C22H39ClN2O6SPurity:98.81% - >99.99%Color and Shape:White SolidMolecular weight:495.07E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Formula:C17H12N4O2SPurity:98.31% - 99.11%Color and Shape:SolidMolecular weight:336.37ILK-IN-3
CAS:<p>ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.</p>Formula:C10H12N6OPurity:99.69%Color and Shape:SolidMolecular weight:232.24Cyclo(RGDyK) trifluoroacetate
CAS:<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Formula:C31H43F6N9O12Purity:95.28% - ≥95%Color and Shape:SolidMolecular weight:847.72TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Formula:C24H21Cl2NO5Purity:98.98%Color and Shape:SolidMolecular weight:474.33BIO-1211
CAS:<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Formula:C36H48N6O9Purity:99.33%Color and Shape:SolidMolecular weight:708.8Eptifibatide acetate (148031-34-9 free base)
CAS:<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Formula:C35H49N11O9S2·xC2H4O2Purity:99.7% - 99.87%Color and Shape:SolidMolecular weight:831.96 (free base)GPRP acetate (67869-62-9 free base)
CAS:<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Formula:C20H35N7O7Purity:>99.99%Color and Shape:SolidMolecular weight:485.53Bexotegrast
CAS:<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Formula:C27H36N6O3Purity:99.53%Color and Shape:SolidMolecular weight:492.61Etaracizumab
CAS:<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Purity:96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.3 (kDa)Muromonab
CAS:<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Purity:95% - 97.51% (SEC-HPLC)Color and Shape:LiquidRO0270608
CAS:<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Formula:C24H19Cl3N2O4Purity:98.26%Color and Shape:SolidMolecular weight:505.78Voxalatamab
CAS:<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Color and Shape:LiquidRovelizumab
CAS:<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Color and Shape:LiquidVepsitamab
CAS:<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Color and Shape:LiquidCevostamab
CAS:<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Color and Shape:LiquidPavurutamab
CAS:<p>Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.</p>Color and Shape:LiquidEnlimomab
CAS:<p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>Color and Shape:LiquidAnti-Mouse IL-1a Antibody (ALF-161)
<p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>Purity:98%Color and Shape:Odour LiquidPasotuxizumab
CAS:<p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.</p>Color and Shape:LiquidUbamatamab
CAS:<p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>Color and Shape:LiquidVatelizumab
CAS:<p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>Purity:95%Color and Shape:LiquidTepoditamab
CAS:<p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>Color and Shape:LiquidVonsetamig
CAS:<p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>Color and Shape:LiquidFlotetuzumab
CAS:<p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>Color and Shape:LiquidLinvoseltamab
CAS:<p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>Color and Shape:LiquidVibecotamab
CAS:<p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>Color and Shape:LiquidObrindatamab
CAS:<p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>Color and Shape:LiquidPacanalotamab
CAS:<p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>Color and Shape:LiquidOS-2966
<p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>Purity:95%Color and Shape:Odour LiquidAnti-Mouse CD3ε Antibody (145-2C11)
<p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>Purity:99%Color and Shape:Odour LiquidGresonitamab
CAS:<p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>Color and Shape:LiquidSB273005
CAS:<p>SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.</p>Formula:C22H24F3N3O4Purity:99.58%Color and Shape:SolidMolecular weight:451.44Tirofiban
CAS:<p>Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.</p>Formula:C22H36N2O5SPurity:99.83%Color and Shape:SolidMolecular weight:440.6GR 144053 trihydrochloride
CAS:<p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>Formula:C18H30Cl3N5O2Purity:98%Color and Shape:SolidMolecular weight:454.82Sibrafiban
CAS:<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Formula:C20H28N4O6Color and Shape:SolidMolecular weight:420.46UR-3216
CAS:<p>UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.</p>Formula:C27H29N7O7Purity:98%Color and Shape:SolidMolecular weight:563.56L 703014
CAS:<p>L 703014 is an antagonist of the fibrinogen receptor.</p>Formula:C24H34N4O4Purity:98%Color and Shape:SolidMolecular weight:442.55Balamapimod
CAS:<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Formula:C30H32ClN7OSPurity:98%Color and Shape:SolidMolecular weight:574.14BMS-587101
CAS:<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Formula:C26H20Cl2N4O4SColor and Shape:SolidMolecular weight:555.43BMS-688521
CAS:<p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>Formula:C26H19Cl2N5O4Purity:98.87%Color and Shape:SolidMolecular weight:536.37MK-0668
CAS:<p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>Formula:C31H30Cl2N6O6SColor and Shape:SolidMolecular weight:685.58NSC47924
CAS:<p>NSC47924 is a laminin receptor (LR) inhibitor.</p>Formula:C18H17NO2Purity:98%Color and Shape:SolidMolecular weight:279.33Zalunfiban
CAS:<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Formula:C16H18N8O2SColor and Shape:SolidMolecular weight:386.43TCS 2314
CAS:<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Formula:C28H34N4O6Purity:98%Color and Shape:SolidMolecular weight:522.59Chrysotobibenzyl
CAS:<p>Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.</p>Formula:C19H24O5Color and Shape:SolidMolecular weight:332.39αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Formula:C28H35F3N6O8SPurity:98%Color and Shape:SolidMolecular weight:672.67Zaurategrast ethyl ester sulfate
CAS:<p>Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.</p>Formula:C56H60Br2N8O10SPurity:98%Color and Shape:SolidMolecular weight:1197.01RUC-1
CAS:<p>RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.</p>Formula:C11H15N5OSPurity:98%Color and Shape:SolidMolecular weight:265.33Zaurategrast ethyl ester
CAS:<p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>Formula:C28H29BrN4O3Purity:98%Color and Shape:SolidMolecular weight:549.46IMB-10
CAS:<p>IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.</p>Formula:C19H15NOS2Color and Shape:SolidMolecular weight:337.46Ro 43-5054
CAS:<p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>Formula:C24H27N5O7Purity:98%Color and Shape:SolidMolecular weight:497.5BOP sodium
CAS:<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Formula:C25H29N3NaO7SColor and Shape:SolidMolecular weight:538.57GSK-3008348
CAS:<p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>Formula:C29H37N5O2Purity:99.547%Color and Shape:SolidMolecular weight:487.64Valategrast
CAS:<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Formula:C30H32Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:604.95Valategrast hydrochloride
CAS:<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Formula:C30H33Cl4N3O4Purity:98%Color and Shape:SolidMolecular weight:641.41CLT-28643
CAS:<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Formula:C19H17N3O4Purity:99.89%Color and Shape:SolidMolecular weight:351.36Integrin-IN-2
CAS:<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Formula:C27H30N4O3Purity:98%Color and Shape:SolidMolecular weight:458.55XVA143
CAS:<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Formula:C25H21Cl2N3O8Color and Shape:SolidMolecular weight:562.36Integrin modulator 1
CAS:<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Formula:C13H14N2O4Purity:99.61%Color and Shape:SolidMolecular weight:262.26Firategrast
CAS:<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Formula:C27H27F2NO6Purity:99.16%Color and Shape:SolidMolecular weight:499.5Elarofiban
CAS:<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Formula:C22H32N4O4Purity:98.76%Color and Shape:SolidMolecular weight:416.513-Hydroxyxanthone
CAS:<p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>Formula:C13H8O3Purity:98%Color and Shape:SolidMolecular weight:212.2ICAM-1-IN-1
CAS:<p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>Formula:C15H11BrN2O2SPurity:99.67%Color and Shape:SolidMolecular weight:363.23BI-1950
CAS:<p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>Formula:C32H26Cl2FN7O3Purity:98%Color and Shape:SolidMolecular weight:646.5Teclistamab
CAS:<p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>Purity:95%Color and Shape:LiquidSynstatin (92-119)
CAS:<p>Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and</p>Formula:C133H207N35O46Purity:98%Color and Shape:SolidMolecular weight:3032.27TAK 029
CAS:<p>TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.</p>Formula:C19H23N5O7Color and Shape:SolidMolecular weight:433.42αvβ6 integrin inhibitor 2
CAS:<p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>Formula:C21H30N4O3Purity:98%Color and Shape:SolidMolecular weight:386.49Lotrafiban
CAS:<p>Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.</p>Formula:C23H32N4O4Color and Shape:SolidMolecular weight:428.52JNJ-26076713
CAS:<p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>Formula:C29H38N4O3Purity:98%Color and Shape:SolidMolecular weight:490.64SB-267268
CAS:<p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>Formula:C22H24F3N3O4Purity:98%Color and Shape:SolidMolecular weight:451.44Zaurategrast
CAS:<p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>Formula:C26H25BrN4O3Purity:98%Color and Shape:SolidMolecular weight:521.41Solitomab
CAS:<p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>Color and Shape:LiquidCarotegrast
CAS:<p>Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.</p>Formula:C27H24Cl2N4O5Color and Shape:SolidMolecular weight:555.41Tirofiban HCl
CAS:<p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>Formula:C22H37ClN2O5SPurity:98%Color and Shape:SolidMolecular weight:477.06
