Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Found 227 products of "Ferroptosis"
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Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurity:99.25% - >99.99%Color and Shape:SolidMolecular weight:259.33Ref: TM-T1847
5mg34.00€10mg50.00€25mg78.00€50mg107.00€100mg166.00€200mg236.00€500mg398.00€1mL*10mM (DMSO)50.00€Siramesine hydrochloride
CAS:Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibitFormula:C30H32ClFN2OPurity:99.72% - >99.99%Color and Shape:SolidMolecular weight:491.04Ref: TM-T1885
1mg57.00€2mg84.00€5mg105.00€10mg170.00€25mg334.00€50mg500.00€100mg705.00€1mL*10mM (DMSO)114.00€Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formula:C32H43NO4Purity:97.81% - 99.09%Color and Shape:SolidMolecular weight:505.69Trigonelline
CAS:Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.Formula:C7H7NO2Purity:97.585% - 99.49%Color and Shape:Prisms Aqueous From Alcohol + Water SolidMolecular weight:137.14WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Formula:C28H38O6Purity:97.41% - 99.99%Color and Shape:SolidMolecular weight:470.60Ref: TM-T5687
1mg80.00€5mg251.00€10mg371.00€25mg620.00€50mg880.00€100mg1,189.00€500mg2,385.00€1mL*10mM (DMSO)288.00€PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purity:99.22%Color and Shape:SolidMolecular weight:185.22Ref: TM-T6954
5mg49.00€10mg70.00€25mg133.00€50mg195.00€100mg349.00€200mg518.00€500mg830.00€1mL*10mM (DMSO)54.00€Alogliptin Benzoate
CAS:Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.Formula:C25H27N5O4Purity:99.94% - >99.99%Color and Shape:White PowderMolecular weight:461.51Alogliptin
CAS:Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9Formula:C18H21N5O2Purity:99.63%Color and Shape:SolidMolecular weight:339.39Ref: TM-T6192
2mg34.00€5mg49.00€10mg60.00€25mg81.00€50mg92.00€100mg129.00€200mg178.00€1mL*10mM (DMSO)50.00€Atorvastatin hemicalcium salt
CAS:Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.Formula:C33H34FN2O5CaPurity:99.27% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:577.67Erastin
CAS:Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!Formula:C30H31ClN4O4Purity:98% - 99.82%Color and Shape:SolidMolecular weight:547.04Ref: TM-T1765
1mg46.00€2x1mg59.00€5x1mg93.00€10x1mg120.00€25x1mg192.00€50x1mg284.00€100x1mg421.00€200x1mg618.00€Trolox
CAS:Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.Formula:C14H18O4Purity:98.90% - 99.90%Color and Shape:White To Fainly Beige Crystalline PowderMolecular weight:250.29FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Formula:C25H31N3O5S2Purity:99.72% - 99.78%Color and Shape:SolidMolecular weight:517.66Ref: TM-T4066
2mg42.00€5mg63.00€10mg89.00€25mg192.00€50mg341.00€100mg535.00€200mg748.00€1mL*10mM (DMSO)72.00€Chrysosplenetin
CAS:Chrysosplenetin is a metabolic inhibitor of artemisinin.Formula:C19H18O8Purity:97.43% - 98.4%Color and Shape:SolidMolecular weight:374.34Ref: TM-TJS1159
1mg57.00€5mg120.00€10mg178.00€25mg329.00€50mg485.00€100mg692.00€500mg1,404.00€1mL*10mM (DMSO)215.00€Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurity:97.71% - >99.99%Color and Shape:SolidMolecular weight:367.3Pifithrin-β hydrobromide
CAS:Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.Formula:C16H17BrN2SPurity:99.24% - 99.74%Color and Shape:SolidMolecular weight:349.29Liproxstatin-1 hydrochloride
CAS:Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].Formula:C19H22Cl2N4Color and Shape:SolidMolecular weight:377.31L-Buthionine-(S,R)-sulfoximine hydrochloride
L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.Formula:C8H19ClN2O3SColor and Shape:SolidMolecular weight:258.77Levobupivacaine hydrochloride
CAS:Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Formula:C18H28N2O·HClPurity:99.74%Color and Shape:White Crystalline PowderMolecular weight:324.89Ammonium iron(III) citrate
CAS:Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.Formula:C12H22FeN3O14Purity:98%Color and Shape:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaMolecular weight:488.16Pioglitazone potassium
CAS:Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.Formula:C19H19KN2O3SColor and Shape:SolidMolecular weight:394.53
