Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Found 229 products for "Ferroptosis".
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Ciclopirox
CAS:Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Formula:C12H17NO2Purity:99.78% - 99.78%Color and Shape:Yellow SolidMolecular weight:207.27Butylhydroxyanisole
CAS:BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.Formula:C11H16O2Purity:99.54% - 99.63%Color and Shape:SolidMolecular weight:180.25Pioglitazone
CAS:Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!Formula:C19H20N2O3SPurity:95% - 99.82%Color and Shape:White PowderMolecular weight:356.44Artesunate
CAS:Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.Formula:C19H28O8Purity:97.67% - 99.9%Color and Shape:White SolidMolecular weight:384.42Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formula:C18H14N4O5SPurity:98.00% - 99.28%Color and Shape:Yellow SolidMolecular weight:398.39Deferiprone
CAS:Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.Formula:C7H9NO2Purity:99.58% - ≥95%Color and Shape:White SolidMolecular weight:139.15Dopamine hydrochloride
CAS:Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter, dopamine receptors (D1-5 receptors) (EC50=2.7 nM). High-Quality, Low-Cost!Formula:C8H12ClNO2Purity:99.47% - 99.95%Color and Shape:White SolidMolecular weight:189.64NVS-ZP7-4
CAS:NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).Formula:C28H28FN5OSPurity:99.86%Color and Shape:SolidMolecular weight:501.62Ref: TM-T12277
1mg67.00€5mg147.00€1mL*10mM (DMSO)164.00€10mg250.00€25mg505.00€50mg767.00€100mg1,054.00€L-Glutathione reduced
CAS:L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.Formula:C10H17N3O6SPurity:97.37% - 99.99%Color and Shape:White SolidMolecular weight:307.32Baicalein
CAS:Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.Formula:C15H10O5Purity:97.29% - 99.40%Color and Shape:Yellow SolidMolecular weight:270.24Ethylenediaminetetraacetic acid trisodium salt
CAS:Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.Formula:C10H13N2Na3O8Purity:99.92% - 99.96%Color and Shape:White SolidMolecular weight:358.19Sorafenib
CAS:Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Formula:C21H16ClF3N4O3Purity:98% - 99.89%Color and Shape:White SolidMolecular weight:464.82Imidazole ketone erastin
CAS:View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.Formula:C35H35ClN6O5Purity:98.48% - 99.89%Color and Shape:Yellow SolidMolecular weight:655.14Ref: TM-T5523
1mg66.00€2mg92.00€5mg144.00€1mL*10mM (DMSO)161.00€10mg185.00€25mg318.00€50mg485.00€100mg640.00€DL-Glutamine
CAS:DL-Glutamine, a non-essential amino acid, is abundant in the body, aids metabolism, carries nitrogen, and fuels cells.Formula:C5H10N2O3Purity:99.89% - 99.98%Color and Shape:White Crystalline Powder White Crystalline PowderMolecular weight:146.14Butylated hydroxytoluene
CAS:Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.Formula:C15H24OPurity:99.72%Color and Shape:SolidMolecular weight:220.35Curcumin
CAS:Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.Formula:C21H20O6Purity:95% - 99.91%Color and Shape:SolidMolecular weight:368.38iFSP1
CAS:iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverseFormula:C20H13N5Purity:98.74% - 99.74%Color and Shape:SolidMolecular weight:323.35FSEN1
CAS:FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.Formula:C22H22BrN5OSPurity:99.54% - 99.97%Color and Shape:White SolidMolecular weight:484.41Rosiglitazone maleate
CAS:Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.Formula:C22H23N3O7SPurity:99.33% - 99.51%Color and Shape:SolidMolecular weight:473.50Ferumoxytol
CAS:Ferumoxytol is an iron oxide nanoparticle with anti-leukemia properties, specifically against acute myeloid leukemia (AML) cells with low ferroportin (FPN) expression. By increasing intracellular iron levels, Ferumoxytol induces the Fenton reaction to produce reactive oxygen species (ROS), resulting in oxidative stress and ferroptosis. It selectively kills leukemia cells with low FPN expression while sparing normal cells, making it useful for studying leukemia targeting iron metabolism abnormalities.Color and Shape:Solid
