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CDK

CDK

CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.

Found 500 products of "CDK"

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  • Garcinone C
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    Garcinone C

    CAS:
    <p>Garcinone C, a xanthone from Garcinia oblongifolia, is anti-inflammatory, promotes healing, and may fight some cancers.</p>
    Formula:C23H26O7
    Purity:99.13% - 99.92%
    Color and Shape:Solid
    Molecular weight:414.45

    Ref: TM-TN1673

  • Trilaciclib hydrochloride
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    Trilaciclib hydrochloride

    CAS:
    <p>Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).</p>
    Formula:C24H32Cl2N8O
    Purity:99.69% - 99.89%
    Color and Shape:Solid
    Molecular weight:519.47

    Ref: TM-T13202

  • Cyclin K degrader 1
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    Cyclin K degrader 1

    <p>Cyclin K degrader 1 is a Cyclin K degrader.Cyclin K degrader 1 is a degrader converted from AT-7519.Cyclin K degrader 1 has weak degrading activity against Cyclin K but does not result in a sustained decrease in degradation affinity.Cyclin K degrader 1 is a degrader converted from AT-7519.</p>
    Formula:C23H17Cl2N5O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:466.32

    Ref: TM-T83652

  • (±)-Enitociclib
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    (±)-Enitociclib

    CAS:
    <p>(±)-Enitociclib ((±)-BAY-1251152) is a racemic mixture of BAY-1251152. BAY-1251152 is highly selective inhibitor of PTEF/CDK9.</p>
    Formula:C19H18F2N4O2S
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:404.43

    Ref: TM-T13467

  • Samuraciclib hydrochloride
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    Samuraciclib hydrochloride

    CAS:
    <p>Samuraciclib HCl is an oral CDK7 inhibitor (IC50: 41 nM), 45-230x selective over CDK1/2/5/9, inhibiting breast cancer growth (GI50: 0.2-0.3 μM).</p>
    Formula:C22H31ClN6O
    Purity:98.99% - 99.8%
    Color and Shape:Solid
    Molecular weight:430.97

    Ref: TM-T10898

  • (R)​-​CR8
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    (R)​-​CR8

    CAS:
    <p>(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.</p>
    Formula:C24H29N7O
    Purity:98.41%
    Color and Shape:Solid
    Molecular weight:431.53

    Ref: TM-T12617L

  • Ca2+ channel agonist 1
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    Ca2+ channel agonist 1

    CAS:
    <p>Ca2+ channel agonist 1 activates N-type Ca2+ channels and inhibits Cdk2 (EC50: 14.23 μM/3.34 μM) for motor nerve issues.</p>
    Formula:C19H26N6O
    Purity:97.71%
    Color and Shape:Solid
    Molecular weight:354.45

    Ref: TM-T10659

  • hSMG-1 inhibitor 11j
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    hSMG-1 inhibitor 11j

    CAS:
    <p>hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, &gt;455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.</p>
    Formula:C27H28ClN7O3S
    Purity:99.22% - 99.65%
    Color and Shape:Solid
    Molecular weight:566.07

    Ref: TM-T8884

  • Avotaciclib
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    Avotaciclib

    CAS:
    <p>Avotaciclib (BEY1107) is a potent and orally active cyclin dependent kinase 1 (CDK1) inhibitor.Avotaciclib can be used to study locally advanced or metastatic</p>
    Formula:C13H11N7O
    Purity:98.02%
    Color and Shape:Solid
    Molecular weight:281.27

    Ref: TM-T39403

  • XPW1
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    XPW1

    CAS:
    <p>XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.</p>
    Formula:C36H39ClFN7O2
    Purity:98.08%
    Color and Shape:Soild
    Molecular weight:656.19

    Ref: TM-T77810

  • NVP-2
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    NVP-2

    CAS:
    <p>NVP-2 selectively inhibits CDK9 (IC50: 0.514 nM), prompts apoptosis, and affects other CDKs (IC50: 0.584-0.706 μM).</p>
    Formula:C27H37ClN6O2
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:513.07

    Ref: TM-T16363

  • CDKI-73
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    CDKI-73

    CAS:
    <p>CDKI-73: strong CDK9 blocker, Ki 4 nM, kills CLL cells selectively, aids cisplatin.</p>
    Formula:C15H15FN6O2S2
    Purity:98.11%
    Color and Shape:Solid
    Molecular weight:394.45

    Ref: TM-T14919

  • CDK4/6-IN-2
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    CDK4/6-IN-2

    CAS:
    <p>CDK4/6-IN-2 是一种CDK4和CDK6抑制剂，IC50分别为 2.7 和 16 nM。</p>
    Formula:C27H32F2N8
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:506.59

    Ref: TM-T10736

  • Ribociclib succinate
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    Ribociclib succinate

    CAS:
    <p>Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).</p>
    Formula:C27H36N8O5
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:552.63

    Ref: TM-T15732

  • CDK2-IN-4
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    CDK2-IN-4

    CAS:
    <p>CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.</p>
    Formula:C23H18N6O2S
    Purity:97.24% - 99.10%
    Color and Shape:Solid
    Molecular weight:442.49

    Ref: TM-T14916

  • Amantadine hydrochloride
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    Amantadine hydrochloride

    CAS:
    <p>Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.</p>
    Formula:C10H18ClN
    Purity:99.98%
    Color and Shape:Solid Crystalline
    Molecular weight:187.71

    Ref: TM-T1406

  • Cirtuvivint
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    Cirtuvivint

    CAS:
    <p>Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.</p>
    Formula:C24H25N7O
    Purity:99.46% - >99.99%
    Color and Shape:Solid
    Molecular weight:427.5

    Ref: TM-T39608

  • BRD6989
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    BRD6989

    CAS:
    <p>BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.</p>
    Formula:C16H16N4
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:264.33

    Ref: TM-T14778

  • Lerociclib dihydrochloride
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    Lerociclib dihydrochloride

    CAS:
    <p>Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/</p>
    Formula:C26H36Cl2N8O
    Purity:97.4%
    Color and Shape:Solid
    Molecular weight:547.52

    Ref: TM-T11345L

  • NU6140
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    NU6140

    CAS:
    <p>NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).</p>
    Formula:C23H30N6O2
    Purity:98.33%
    Color and Shape:Solid
    Molecular weight:422.52

    Ref: TM-T16359